Ginsenoside-Enriched Extract from Black Ginseng Anti-Fatigue Effects by Improving Antioxidant Capacity and Mitochondrial Function by Shunji Ge, Jiating Li, Xueyue Tai, Kuo Wang, Liyan Huang, Weixin Su, Guoqi Zhang, Bao Zhong, Fenglin Li

“…Additionally, gene expression analysis showed significant upregulation of key antioxidant and mitochondrial function genes, including those encoding cationic amino acid transporter 2, stearoyl-CoA desaturase-2, nuclear respiratory factor 1, nuclear factor erythroid 2-related factor 2, mitochondrial transcription factor A, cytochrome c oxidase II, and NADH–ubiquinone oxidoreductase core subunit 1, particularly in the HBG group, indicating enhanced antioxidant capacity and improved mitochondrial function. …”
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Effect of nano-hydroxyapatite filling on masticatory function and gingival sulcular fluid inflammatory factor levels in periapical inflammation by Honghui Xie, Aihong Tan, Zhijian Su, Chao Pan, Shuangjiang Li, Haibo Xiao

“…These include the promotion of recovery of masticatory function, the regulation of inflammatory factor expression in gingival sulcular fluid, and the enhancement of clinical efficacy and filling effect. …”
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Design of a Robust Flow Cytometric Approach for Phenotypical and Functional Analysis of Human Monocyte Subsets in Health and Disease by Talia Ahrazoglu, Jennifer Isabel Kluczny, Patricia Kleimann, Lisa-Marie Irschfeld, Fabian Theodor Nienhaus, Florian Bönner, Norbert Gerdes, Sebastian Temme

“…Human monocytes can be subdivided into phenotypically and functionally different classical, intermediate and non-classical monocytes according to the cell surface expression of CD14 and CD16. …”
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Functional Characterization of Grapevine <i>VviMYC4</i> in Regulating Drought Tolerance by Mediating Flavonol Biosynthesis by Yiting Tan, Wenjuan Wang, Wenbo Tian, Beibei Wang, Qifeng Zhao, Jinjun Liang, Wei Zhao, Pengfei Wen

“…Phylogenetic analysis confirmed its homology with the grapevine VviMYC2 and similarity in function. The expression of <i>VviMYC4</i> in ‘Cabernet Sauvignon’ grapevine seedling leaves increased initially and then decreased during prolonged drought stress. …”
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Functional Characterization of Dual-Initiation Codon-Derived V2 Proteins in Tomato Yellow Leaf Curl Virus by Zhiyuan Wang, Pan Gong, Siwen Zhao, Fangfang Li, Xueping Zhou

“…Mutant viruses declined progressively in tomato, indicating host defense clearance. Heterologous co-expression of both isoforms via potato virus X induced systemic necrosis in <i>N. benthamiana</i>, demonstrating functional synergy between isoforms. …”
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Surface Functionalized Polyhydroxyalkanoate Nanoparticles via SpyTag–SpyCatcher System for Targeted Breast Cancer Treatment by Jin Young Heo, Min Kyung Sung, Seonhye Jang, Hansol Kim, Youngdo Jeong, Dong-Jin Jang, Sang-Jae Lee, Seong-Bo Kim, Sung Tae Kim

“…Dual-functionalized NPs exhibited synergistic or attenuated effects based on the HER2 expression levels, highlighting the critical role of ligand composition in targeted delivery. …”
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Characterization and functional evaluation of goat PDX1 regulatory modules through comparative analysis of conserved interspecies homologs by Naeimeh Rezaei, Kianoush Dormiani, Abbas Kiani-Esfahani, Somayeh Mirdamadian, Mohsen Rahmani, Farnoosh Jafarpour, Mohammad Hossein Nasr-Esfahani

“…Abstract PDX1 is a crucial transcription factor in pancreas development and mature β-cell function. However, the regulation of PDX1 expression in larger animals mirroring human pancreas morphogenesis and endocrine maturation remains poorly understood. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…Results Here, we show that enhancer mutation of MEF2C reduces own gene expression and consequently impairs mitochondrial function in motor neurons. …”
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New insights into the function and mechanisms of piRNA PMLCPIR in promoting PM2.5-induced lung cancer by Lin Xu, Wanli Ma, Xiaoyu Huo, Jiao Luo, Ruoxi Li, Xiaoxiao Zhu, Xiangbin Kong, Kunming Zhao, Yuan Jin, Meihua Zhang, Xianshu Li, Ling Wang, Wei Han, Dianke Yu

“…However, their biological function and mechanism in PM2.5-induced lung cancer have not been thoroughly investigated. …”
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Exploring the therapeutic potential of Danggui Shaoyao San in nephrotic syndrome: Impact on skin sodium content and renal function by Qingzhen Xiang, Lianghou Ni, Zaiping Xu, Xiaowen Ma, Yunlai Wang, Zihua Xuan, Fan Xu

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Cardiac function of colorectal cancer mice is remotely controlled by gut microbiota: regulating serum metabolites and myocardial cytokines by Zhan-Kui Gao, Chao-Yuan Fan, Bo-Wen Zhang, Jia-Xin Geng, Xing Han, Dan-Qi Xu, Muhammad Arshad, Hao-Xuan Sun, Jiong-Yi Li, Xiangyuan Jin, Xiao-Qin Mu

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Genome‐wide identification of WOX family members in rose and functional analysis of RcWUS1 in embryogenic transformation by Xue Bai, Qi Fu, Weikun Jing, Hao Zhang, Hongying Jian, Xianqin Qiu, Hongjie Li, Qigang Wang, Shunting Yang, Yiping Zhang, Huichun Wang, Lihua Wang, Kaixue Tang, Ying Bao, Huijun Yan

“…Here, we analyzed WOX family genes of three Rosa species and explored their potential functions in Rosa. A total of 351 WOX genes were identified from Rosa chinensis ‘Old Blush’ (208), Rosa wichuraiana ‘Basye's Thornless’ (21) and Rosa rugosa (122). …”
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Docosahexaenoic Acid Supplementation in Postnatal Growth Restricted Rats Does Not Normalize Lung Function or PPARγ Activity by Adrienne J. Cohen, Wesley R. Chidester, Daniel T. Wray, Nicolette Jessen, Aimee Jones, Cheylah Bitsui, James Zhao, J. Alan Maschek, James E. Cox, Camilia R. Martin, Lisa A. Joss-Moore

“…We previously developed a rat model of postnatal growth restriction (PGR) in which pups have impaired lung function and altered PPARγ activity. Here, we use our PGR rat model to assess the effects of DHA supplementation on lung outcomes. …”
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Effect and Mechanism of Yisui Fuyongtang (YSFYT) Decoction on Cognitive Function and Synaptic Plasticity in Rats with Vascular Cognitive Impairment by Tingliang Gong, Zhaoliang Luo, Li Huang, Caixian Xiao, Junlu Yi, Junfeng Yan, Qian Chen, Weihong Li, Wenqiang Tao

“…Clinical medications have found that Yisui Fuyongtang (YSFYT) Decoction is effective in improving neurological signs and learning-memory functions in patients who develop white matter lesions and whole brain atrophy. …”
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Identification and functional characteristics of IL-8 and its potential receptor CXCR1/2 in Siberian hybrid sturgeon by Shiyong Yang, Rong Wei, Xinrui Lyu, Yujie Lv, Yang Xiao, Jiayun Wu, Xiaogang Du, Yunkun Li

“…Their molecular features, tissue distribution and immune function were analyzed. The CDS length of IL-8 and the receptor genes was 288 bp, 1,135 bp, 1,135 bp, 1,061 bp, and 1,078 bp, respectively. …”
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Disrupted functional connectivity between visual and emotional networks in psychosis risk syndromes through representational similarity analysis by Xi Ruan, Lang Zhang, Mingjun Duan, Dezhong Yao, Dezhong Yao, Cheng Luo, Cheng Luo, Cheng Luo, Hui He

“…Each subject underwent task-based functional magnetic resonance imaging (fMRI), which included steady-state visual evoked potentials (SSVEP) and expression matching tasks. …”
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Establishment of an infectious clone of the porcine transmissible gastroenteritis virus and a study on the location and function of accessory protein 3 by Zhenye Hao, Zhenye Hao, Lifei Liu, Lifei Liu, Shuai Wang, Shuai Wang, Yanping Jiang, Yanping Jiang, Jiaxuan Li, Jiaxuan Li, Wen Cui, Wen Cui, Li Wang, Li Wang, Yijing Li, Yijing Li

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The function of CD164 in breast cancer and its possibility as a molecular biomarker: bioinformatics analysis and experimental validation by Mengxin Li, Juanjuan Mao, Guang Wang, Jiasi Chen, Jinghui Hong, Xue Wang, Baoling Liang, Dong Song

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Exploration of the mechanism underlying the impact of artificial light on guinea pig ovarian function via proteomics and acetylation analyses by Jiayu Shi, Yuliang Wang, Linfang Li, Ruxin Wang, Yao Peng, Tingting Zhou, Donglai Hu, Jie Chen, Yong Tan

“…Objective: This study aims to explore the effects of artificial light on ovarian function in female guinea pigs and the possible mechanism. …”
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Identification of functional SNP associated with sperm quality in porcine ANXA5 that contributes to the growth of immature Sertoli cell by Mingyang Han, Diwen Yao, Yuyang Song, Yuhang Liu, Zhihua Chen, Jialian Li, Fenge Li, Xiuqin Yang, Lihe Dai, Buyue Niu

“…The aim of this study was to explore the effect of ANXA5 in the growth of swine Sertoli cells and identify its functional variations. Firstly, the expression of porcine ANXA5 in different tissues was detected by semi-quantitative RT-PCR and its effect on the proliferation of Sertoli cells was evaluated by CCK8, EdU, flow cytometry analyses and qRT-PCR. …”
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