Development of nanofiber facial mask inspired by the multi-function of dried ginger (Zingiberis Rhizoma) essential oil by Yiwen Hao, Xia Lin, Wenwen Liu, Tinghongyang Jiang, Xing Zhang, Shasha Yang, You Huang, Wenjing Lai, Chaomei Fu, Zhen Zhang

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IL-10 Dampens the Th1 and Tc Activation through Modulating DC Functions in BCG Vaccination by Hui Xu, Yanjuan Jia, Yonghong Li, Chaojun Wei, Wanxia Wang, Rui Guo, Jing Jia, Yu Wu, Zhenhao Li, Zhenhong Wei, Xiaoming Qi, Yuanting Li, Xiaoling Gao

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Archaeal LOV domains from Lake Diamante: first functional characterization of a halo-adapted photoreceptor by Lorena Valle, Lorena Valle, Yonathan J. Coronel, Yonathan J. Coronel, Guillermina E. Bravo, Joaquín A. Díaz, Virginia Helena Albarracín, Virginia Helena Albarracín, María E. Farías, Inés Abatedaga

“…Importantly, ALovD-1 exhibited remarkable halophilic characteristics, maintaining photocycling functionality at salt concentrations as high as 3 M monovalent salts. …”
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Functional exhaustion of CD4⁺T cells in HIV/HCV coinfected HAART-treated patients by V. V. Vlasova, L. B. Korolevskaya, O. A. Loginova, N. G. Shmagel, E. V. Saidakova

“…These data suggest that HCV coinfection leads to pronounced functional exhaustion of CD4+T cells and may aggravate the course of HIVinfection in patients receiving HAART.…”
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Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control by Mary Philip, Mary K Washington, Joseph T Roland, Carlos R Detrés Román, Megan M Erwin, Michael W Rudloff, Frank Revetta, Kristen A Murray, Natalie R Favret, Jessica J Roetman

“…We assessed the immunophenotype (CD44, PD1, TCF1, and TOX expression) and function (TNFα and IFNγ cytokine production) of tumor/TAG-specific CD8 T cells in mice with early and late liver lesions by flow cytometry. …”
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Cadmium targeting transcription factor EB to inhibit autophagy-lysosome function contributes to acute kidney injury by Peng-Fei Dong, Tian-Bin Liu, Kai Chen, Dan Li, Yue Li, Cai-Yu Lian, Zhen-Yong Wang, Lin Wang

“…Objectives: Transcription factor EB (TFEB) is a critical transcription regulator that modulates autophagy-lysosome function, but its role in Cd-induced AKI is yet to be elucidated. …”
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Evaluation of the efficacy of Tai Chi on the cognitive function of patients with mild cognitive dysfunction and research on its mechanism by Lin Lin, Lin Lin, Yao-Xi He, Quan Wen, Jia-Yang Liu, Yu Dai, Yu-Zhe Fei, Hang Li, Chang-Qing Li, Huan Zhou, Huan Zhou

“…This enhancement may be attributed to an increased expression of serum BDNF.DiscussionIn conclusion, our study underscores the potential of Tai Chi in ameliorating cognitive function among elderly patients with mild cognitive impairment, thereby offering significant implications for clinical prevention and treatment strategies targeting this condition.…”
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The cell adhesion molecule CD44 acts as a modulator of 5-HT7 receptor functions by Saskia Borsdorf, Andre Zeug, Yuxin Wu, Elena Mitroshina, Maria Vedunova, Supriya A. Gaitonde, Michel Bouvier, Michael C. Wehr, Josephine Labus, Evgeni Ponimaskin

“…However, the functional consequences of this interaction on 5-HT7R-mediated signaling remained enigmatic. …”
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Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement by Xin Zhang, Chao Yang, Chengle Zhang, Junqiang Wu, Xiang Zhang, Jiayang Gao, Xuejie Wang, Leung Ting Chan, Yiren Zhou, Yujun Chen, Sindy Sing Ting Tam, Shuhang Chen, Yuqian Ma, Wing-Ho Yung, Liting Duan, Liwen Jiang, Yiwen Wang, Kai Liu

“…Abstract Mechanisms underlying functional axonal rewiring after adult mammalian central nervous system (CNS) injuries remain unclear partially due to limited models. …”
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Regulation of Isoleucine on Colonic Barrier Function in Rotavirus-Infected Weanling Piglets and Analysis of Gut Microbiota and Metabolomics by Changsheng Jiang, Weiying Chen, Yanan Yang, Xiaojin Li, Mengmeng Jin, Ahmed H. Ghonaim, Shenghe Li, Man Ren

“…This study aimed to assess the impact of isoleucine supplementation in feed on colonic barrier function, colonic microbiota, and metabolism in RV-infected weanling piglets. …”
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Oryzalin-Induced polyploidy enhances natural metabolite accumulation and functional bioactivities in novel Callisia fragrans genotype by Neha Gupta, Soham Bhattacharya, Jana Žiarovská, Adrish Dutta, Veronika Fialková, Silvia Farkasová, Anna Mascellani Bergo, Jaroslav Havlik, Jan Tauchen, Pavel Novy, Klára Urbanová, Luigi Milella, Eloy Fernández-Cusimamani

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Father’s adolescent body silhouette is associated with offspring asthma, lung function and BMI through DNA methylation by Negusse Tadesse Kitaba, Toril Mørkve Østergaard, Marianne Lønnebotn, Simone Accordini, Francisco Gómez Real, Andrei Malinovschi, Anna Oudin, Bryndis Benediktsdottir, Francisco Javier Callejas González, Leopoldo Palacios Gómez, Mathias Holm, Nils Oskar Jõgi, Shyamali C. Dharmage, Svein Magne Skulstad, Vivi Schlünssen, Cecilie Svanes, John W. Holloway

“…Abstract Boys’ pubertal overweight associates with future offspring’s asthma and low lung function. To identify how paternal overweight is associated with offspring’s DNA methylation (DNAm), we conducted an epigenome-wide association study of father’s body silhouette (FBS) at three timepoints (age 8, voice break and 30) and change in FBS between these times, with offspring DNAm, in the RHINESSA cohort (N = 339). …”
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Mechanism of intestinal flora affecting SLC2A9 transport function to promote the formation of hyperuricemia by Ying Ying, Yi Zhang, Jing Sun, Yong Chen, Huaxiang Wu

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Administration of the KCa channel activator SKA-31 improves endothelial function in the aorta of atherosclerosis-prone mice by O. Daniel Vera, Ramesh C. Mishra, Rayan Khaddaj-Mallat, Liam Hamm, Barak Almarzouq, Yong-Xiang Chen, Darrell D. Belke, Latika Singh, Heike Wulff, Andrew P. Braun, Andrew P. Braun

“…Fatty plaque formation, tissue collagen, α-smooth muscle actin and resident macrophages in the aortic sinus were also unaltered by either treatment vs. vehicle treated Apoe−/− HFD mice.ConclusionOur data show that prolonged administration of the KCa channel activator SKA-31 improved endothelial function without modifying fatty plaque formation in the aorta of Apoe−/− mice.…”
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Functional analysis of the xyloglucan endotransglycosylase/hydrolase gene MdXTH2 in apple fruit firmness formation by Li Liu, Yifeng Feng, Ziqi Han, Yaxiao Song, Jianhua Guo, Jing Yu, Zidun Wang, Hui Wang, Hua Gao, Yazhou Yang, Yuanji Wang, Zhengyang Zhao

“…Here, we identified the gene MdXTH2 by integrating metabolomic and transcriptomic data, and analyzed its function and molecular mechanism in the formation of apple fruit firmness. …”
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HONORING WAR VETERANS AS A COMPONENT OF THE IMPLEMENTATION OF THE SOCIO-ECONOMIC FUNCTION OF THE STATE: ADMINISTRATIVE-LEGAL ASPECT by Liudmyla Sylenko, Serhii Sivkov, Denys Komarnytskyi

“… The article examines the issue of honoring war veterans as an important element of the implementation of the socio-economic function of the state in the conditions of a special period. …”
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Functional characterization of SIZ1 homologs reveals reduced TSWV susceptibility of mutant Nicotiana benthamiana lines by Jelli Venkatesh, Seo-Young Lee, Ghimire Sunita, Jin-Kyung Kwon, Joung-Ho Lee, Byoung-Cheorl Kang

“…Despite considerable research efforts, the specific function of SIZ1 in plants remains largely unknown. …”
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Synergistic effects of alginate oligosaccharide and cyanidin-3-O-glucoside on the amelioration of intestinal barrier function in mice by Jie Li, Yuanjie Guo, Liyuan Ma, Yixiang Liu, Chao Zou, Huiying Kuang, Bing Han, Yingliang Xiao, Yanbo Wang

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Beclin 1 of megakaryocytic lineage cells is locally dispensable for platelet hemostasis but functions distally in bone homeostasis by Lei Li, Chen Zhao, Ruizhi Zhang, Wen Wei, Bowen Liu, Jin Dong, Xueqin Gao, Di Zhang, Xueqing Wang, Meilin Lu, Yumu Zhang, Yao Yu, Na Yuan, Youjia Xu, Jianrong Wang, Yixuan Fang

“…In addition, metformin treatment, which induces SHBG expression, reduced FT and normalized bone mass in Becn1 f/f;Pf4-iCre mice. …”
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Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets by Jie Chong, Jie Chong, Yongming Zhou, Zhi Li, Xiaokai Li, Jinwei Zhang, Jinwei Zhang, Haoran Cao, Jideng Ma, Liangpeng Ge, Liangpeng Ge, Hang Zhong, Hang Zhong, Jing Sun, Jing Sun

“…These findings demonstrate that HDCA exerts microbiota-dependent effects on growth performance, intestinal barrier function, and bile acid metabolism in piglets. Although 0.2 mg/mL HDCA treatment suppressed body weight gain, it potentially enhanced intestinal barrier integrity by activating the TGR5 signaling pathway and increasing the abundance of beneficial bacteria such as Lactobacillus. …”
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