MASP1 in stomach adenocarcinoma: linking diagnosis, prognosis, and tumor immunity by Chuyu Xiao, Fuyang Hong, Guanzi Chen, Wenli Xu, Yusheng Jie

“…Enrichment analyses were conducted to elucidate the functions and pathways associated with MASP1. The relationship between MASP1 expression and tumor immune infiltration was analyzed using single-sample Gene Set Enrichment Analysis (ssGSEA), Cell-type Identification By Estimating Relative Subsets Of RNA Transcripts (CIBERSORT), Estimation of STromal and Immune cells in MAlignant Tumor tissues using Expression data (ESTIMATE), and Spearman correlation methods. …”
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Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning by Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang

“…Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) and gene set enrichment analysis (GSEA) were conducted to explore the biological functions of these genes. LASSO regression and SVM algorithms were employed to identify hub genes. …”
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Translation, cultural adaptation and validation of the Danish version of the haematological malignancy patient-reported outcome measure (HM-PRO) by Sam Salek, Sören Möller, Niels Abildgaard, Tine Rosenberg, Maria Torp Larsen, Peter Asdahl, Kasper Kofod Pedersen, Marie Therese Lassen, Christen Lykkegaard Andersen, Lene Kongsgaard Nielsen

“…Construct validity, internal consistency, dimensionality, item response theory (IRT) and differential item functioning were investigated. Results 295 patients were included for psychometric evaluation; confirmatory factor and bifactor analyses for both HM-PRO parts provided good evidence to support the suggested factor structure (Cronbach’s-α Part-A = 0.81, Part-B = 0.84; Part-A CFA CFI = 0.922, TLI = 0.912; bi-factor CFI = 0.989, TLI = 0.978). …”
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Identification and Characterization of SQUAMOSA Promoter Binding Protein-like Transcription Factor Family Members in <i>Zanthoxylum bungeanum</i> and Their Expression Profiles in R... by Shengshu Wang, Weiming Hu, Xueli Zhang, Yulin Liu, Fen Liu

“…This study will help us gain a deeper understanding of the functions of <i>ZbSPLs</i> and lay a genetic foundation for future breeding of high-quality, highly abiotic resistant varieties of <i>Z. bungeanum</i>.…”
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A Novel Putative Role of TNK1 in Atherosclerotic Inflammation Implicating the Tyk2/STAT1 Pathway by Mei-Hua Bao, Qiao-Li Lv, Hai-Gang Li, Yi-Wen Zhang, Bao-Feng Xu, Bin-Sheng He

“…The present study was to investigate the anti-inflammatory functions and mechanisms of TNK1 in atherosclerosis. …”
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Typical Forms of Plans for Certain Investigative (Search) Actions by O. O. Khan

“…Carrying out a search in the presence of the searched person may include the following elements: a) search situation; b) versions explaining the situation; c) tasks on the situation; d) tactics; e) sequence of search actions; e) distribution of functions of search participants.…”
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Integrated bioinformatics and experiment validation reveal cuproptosis-related biomarkers and therapeutic targets in sepsis-induced myocardial dysfunction by Xuemei Shi, Zhonghan Yan, Ruilin Ding, Fenfen Xia, Yan Du, Xiaojie Wang, Qing Peng

“…Gene Set Enrichment Analysis (GSEA) and single-sample GSEA (ssGSEA) were performed to assess biological functions and immune cell infiltration, respectively. ceRNA and transcription factor networks were constructed to explore gene regulatory mechanisms, while consensus clustering was employed to define cuproptosis-related subtypes. …”
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Analysis of production and financial potential as a basis for developing a strategy for modernizing the Russian economy by Ljudmila I. Rozanova, Sergei V. Tishkov

“…The availability of borrowed capital for the modernization of production systems is differentiated in a spatial aspect. The functioning institutions of the financial market also do not ensure equal access to credit resources for small and medium-sized businesses.The scientific novelty of this study is that the authors identified the main problems of the process of modernization and implementation of innovative developments in the context of high levels of depreciation of production systems and inadequate investment resources. …”
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Machine learning identification of key genes in cardioembolic stroke and atherosclerosis: their association with pan-cancer and immune cells by Tianxiang Zhang, Chunhui Yuan, Mo Chen, Jinjiang Liu, Wei Shao, Ning Cheng

“…A study was conducted to examine differentially expressed genes (DEGs) in healthy individuals and patients diagnosed with CS and AS. …”
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Identification of a Prognosis-Related Risk Signature for Bladder Cancer to Predict Survival and Immune Landscapes by Linhui Wang, Yutao Wang, Jianfeng Wang, Luanfeng Li, Jianbin Bi

“…The potential biological functions of the selected genes were analyzed using CIBERSORT and ESTIMATE algorithms. …”
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Combination of RNA-sequencing data analysis, network pharmacology, molecular docking techniques to investigate the mechanism of Prunella vulgaris L. in the treatment of non-small c... by Yanggang Dan, Yangli Jin, Jing Wang, Lu Wang, Dawei Zheng

“…These “drug-disease” common targets were associated with 100 GO items, including 41 biological processes, 16 cellular components, and 43 molecular functions. KEGG enrichment analysis identified 14 signaling pathways. …”
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Investigates the Role of PANoptosis in Idiopathic Pulmonary Fibrosis and Potential Therapeutic Targets by Xiang Y, Huang G, Luo C, Jiang J, Zhang T, Zeng Q, Zhou F, Du D

“…Exploring potential biological functions and immune cell infiltration abundance through GO/KEGG enrichment analysis and Immune infiltration analysis. …”
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Exome analysis reveals species divergence in TYR and identifies species genetic markers in five endemic Macaca species on Sulawesi Island by Xiaochan Yan, Nami Arakawa, Kanthi Arum Widayati, Laurentia Henrieta Permita Sari Purba, Fahri Fahri, Bambang Suryobroto, Yohey Terai, Hiroo Imai

“…This study aims to investigate highly divergent regions that might contribute to the distinct genetic and phenotypic characteristics differentiating the five Sulawesi macaque species. Additionally, it explores how these genetic differences influence biological functions, and identifies species-specific genetic markers for species identification and conservation. …”
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Giant transposons promote strain heterogeneity in a major fungal pathogen by Emile Gluck-Thaler, Adrian Forsythe, Charles Puerner, Cecilia Gutierrez-Perez, Jason E. Stajich, Daniel Croll, Robert A. Cramer, Aaron A. Vogan

“…Starship-mobilized genes encode diverse functions, including known biofilm-related virulence factors and biosynthetic gene clusters, and many are differentially expressed during infection and antifungal exposure in a strain-specific manner. …”
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Longitudinal Network Relationships Between Symptoms of Deviant Peer Affiliation and Internet Gaming Disorder in Adolescents: Prospective Cohort Study by Tingting Gao, Fengtong Qian, Rui Li, Yimeng Lyu, Yingying Su

“…Targeted interventions could disrupt the cycle of maladaptive behavior by focusing on improving both peer and social functioning during critical developmental periods, ultimately preventing the exacerbation of these behavioral issues over time.…”
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Pan-cancer analysis of GJB5 as a novel prognostic and immunological biomarker by Xiaojuan Yang, Xunjie Cao, Qing Zhu, Hong Wu

“…Abstract Gap junction protein B5 (GJB5, also known as Connexin 31.1) has recently been reported to be downregulated in several cancer types, where it functions primarily as a tumor suppressor in cancers such as melanoma and non-small cell lung cancer (NSCLC). …”
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Transcriptome and Physiological Analysis Reveals the Mechanism of Abscisic Acid in Regulating Cadmium Uptake and Accumulation in the Hyperaccumulator <i>Phytolacca acinosa</i> Roxb... by Qin Xie, Wenting Xu, Qing Wang, Feihong Yao, Yachao Jiang, Haijia Cao, Wanhuang Lin

“…This study identified 5788 differentially expressed genes (DEGs) (2541 up-regulated and 3247 down-regulated). …”
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Effects of <i>Lactiplantibacillus-plantarum</i>-ZG7-Fermented Feed on Laying-Hen Productivity and Intestinal Health by Zhaolong Li, Wenjing Liu, Huini Wu, Song Peng, Mengshi Zhao, Fengqiang Lin, Lu Zhao

“…The downregulated metabolites were functionally linked to ABC transporters and neuroactive ligand–receptor interactions. …”
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Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis by Zhenwei Xie, Cheng Feng, Yude Hong, Libo Chen, Mingyong Li, Weiming Deng

“…In this study, we identified several key genes associated with the prognosis of ccRCC by using integrated bioinformatics.MethodsTwo ccRCC expression profiles were downloaded from Gene Expression Omnibus and one dataset was gained from The Cancer Genome Atlas The Robust Rank Aggregation method was used to analyze the three datasets to gain integrated differentially expressed genes The Gene Ontology and KEGG analysis were performed to explore the potential functions of DEGs. …”
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ANTINOMY OF THE MODERN AVERAGE PROFESSIONAL EDUCATION by A. A. Listvin

“…The inefficiency of the concept of one-leveled SPE and its non-competitiveness against the background of development of an applied bachelor degree at the higher school is shown. It is offered to differentiate programs of basic level for training of skilled workers and the program of the increased level for training of specialists of an average link (technicians, technologists) on the basis of basic level for forming of a single system of continuous professional training and effective functioning of regional systems of professional education. …”
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