Adipose-Derived Mesenchymal Stem Cells Accelerate Diabetic Foot Ulcer Healing by Promoting Macrophage M2 Polarization Through Downregulation of EREG and CSTA by Cao J, Zhang X, Li Z, Zhang S, Guo L, Liu Z, An W, Xu L, Li L, Long X, Yang Y

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Combined Application of High-Throughput Sequencing and Metabolomics to Evaluate the Microbial Mechanisms of Plant-Growth-Promoting Bacteria in Enhancing the Remediation of Cd-Conta... by Shan-Shan Gao, Ying-Jun Zhang, Yang Shao, B. Larry Li, Han Liu, Yu-Ying Li, Xue-Min Ren, Zhao-Jin Chen

“…High-throughput sequencing and metabolomics were used to determine the effects of inoculation on the soil bacterial community composition and microbial metabolic functions associated with hybrid Pennisetum. The results suggest that mutation of <i>Brevibacillus</i> sp. …”
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Identification of a PANoptosis-related long noncoding rna risk signature for prognosis and immunology in colon adenocarcinoma by Yuekai Cui, Jie Mei, Shengsheng Zhao, Bingzi Zhu, Jianhua Lu, Hongzheng Li, Binglong Bai, Weijian Sun, Wenyu Jin, Xueqiong Zhu, Shangrui Rao, Yongdong Yi

“…Specifically, in terms of functionality, AP003555.1 was found to be highly expressed in colon cancer tissue and promoted viability and proliferation while suppressing the apoptosis of colon cancer cells. …”
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Identification of aging-related biomarkers and immune infiltration analysis in renal stones by integrated bioinformatics analysis by Yuanzhao Wang, Nana Chen, Bangqiu Zhang, Pingping Zhuang, Bingtao Tan, Changlong Cai, Niancai He, Hao Nie, Songtao Xiang, Chiwei Chen

“…This study aims to identify potential aging-related biomarkers for RS, explore the functions of aging-associated genes, and investigate the immunological microenvironment in RS. …”
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Multi-omics and experimental validation studies reveal key biomarkers of cellular senescence in diabetic retinopathy by Jinju Li, Hao Yang, Yixuan Lin, Zhaohui Fang

“…Single-cell sequencing and gene set enrichment analysis (GSEA) were employed to determine the cellular location and biological functions of DR-CS key biomarkers, and animal experiments further validated these biomarkers. …”
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Assessing the suitability of the Langevin equation for analyzing measured data through downsampling by Pyei Phyo Lin, Matthias Wächter, Joachim Peinke, M Reza Rahimi Tabar

“…For real-world data that lack Markov properties, we estimate the functions and parameters using the generalized Langevin equation, which incorporates a memory kernel to account for non-Markovian dynamics.…”
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Chitosan-TPP Nanogels for Ocular Delivery of Folic Acid: Release Profile, Corneal Permeation, and Mucoadhesion Assessment by Sebastián G. Bruno, Sofía M. Martínez, Camila Costa Gobbato, Daniela A. Quinteros, Agustina Alaimo, Oscar E. Pérez

“…<b>Background</b>: Folic acid (FA) is essential for cellular functions but has limited ocular bioavailability, restricting its therapeutic effectiveness. …”
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An Analysis of the Gene Expression Associated with Lymph Node Metastasis in Colorectal Cancer by Hongjie Yang, Jiafei Liu, Peishi Jiang, Peng Li, Yuanda Zhou, Zhichun Zhang, Qingsheng Zeng, Min Wang, Luciena Xiao Xiao, Xipeng Zhang, Yi Sun, Siwei Zhu

“…The data sets of CRC patients were collected through the Cancer Gene Atlas database; the differentially expressed genes (DEGs) associated with CRC lymph node metastasis were screened; a protein–protein interaction (PPI) network was constructed; the top 20 hub genes were selected; the Gene Ontology functions and the Kyoto Encyclopedia of Genes and Genomes pathways were enriched and analyzed. …”
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Electronic nose and machine learning for modern meat inspection by Ivan Shtepliuk, Guillem Domènech-Gil, Viktor Almqvist, Arja Helena Kautto, Ivar Vågsholm, Sofia Boqvist, Jens Eriksson, Donatella Puglisi

“…We employed a metal-oxide based gas sensor array of commercially available chemoresistive sensors, functioning as an electronic nose, to differentiate between various categories of 100 pig meat samples collected at a slaughterhouse based on their odor characteristics, including a urine-like smell and post-mortem aging. …”
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Single-cell transcriptomics identify a chemotherapy-resistance related cluster overexpressed CLIC3 in ovarian cancer by Zhefeng Li, Jie Li, Yue Li, Junjie Yi, Xiaoting Zhao, Wentao Yue

“…Using GSVA and cell communication analysis, we explored the unique biological functions and communication characteristics of this resistant subcluster. …”
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Correlation between the use of dried Toad skin-radix clematidis and the development of intestinal dysbiosis and colorectal cancer by Xue-yan Wang, Li-jun Pan, Bing Yang, Yang Liu, Dong-xin Tang

“…On the other hand, the drug repairs certain functions of the microbiota. After the drug enters the intestine, it exerts a positive regulatory effect on the dysbiosis of the intestinal microbiota in rats, partially improving the dysbiosis caused by antibiotics, restoring the balance of CD3+, CD4+, and CD8 + ratios in rats, and partially restoring the anticancer activity of drug-containing plasma. …”
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DNA-Containing Extracellular Structures of Tumor Cells Inhibit the Formation of Neutrophil Extracellular Traps <i>in vitro</i> by A. N. Kazimirskii, J. M. Salmasi, G. V. Poryadin, M. I. Panina, A. E. Kim, A. G. Chakhalian, O. O. Turishcheva

“…Platelets were removed using differential centrifugation. Isolated neutrophils in RPMI-1640 medium were used in short-term culture experiments. …”
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The retrospection of Ukrainian human geography: attempt of the development periodization by Yaroslav Oliynyk, Serhii Shevchuk

“…The study is devoted to thorough justification of a new periodization model of human geography development in Ukraine on the base of objective functioning regularities of science. The topicality and relevance of the given research for the national science were reasoned in the context of absence of accredited development periodization of Ukrainian human geography. …”
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Exploring common genomic biomarkers to disclose common drugs for the treatment of colorectal cancer and hepatocellular carcinoma with type-2 diabetes through transcriptomics analys... by Sabkat Mahmud, Alvira Ajadee, Arnob Sarker, Reaz Ahmmed, Tasfia Noor, Md Al Amin Pappu, Md Saiful Islam, Md Nurul Haque Mollah

“…Further analysis of these cGBs with GO-terms and KEGG pathways revealed shared pathogenetic mechanisms of three diseases, including specific biological processes, molecular functions, cellular components and signaling pathways. …”
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Visual attention and response time to distinguish athletes from non-athletes: A virtual reality study. by Lucia Imperiali, Stefano Borghi, Sara Bizzozero, Elena Prandoni, Ambra Bisio, Antonio La Torre, Roberto Codella

“…Virtual Reality (VR) technology has emerged as a powerful tool, offering an immersive and controlled scenario for examining cognitive functions. In light of the growing adoption of VR-systems, this study aimed to investigate the differences in visual attention and response time (RT) between athletes and non-athletes utilizing a VR-system and evaluate the discriminatory power of VR assessments towards the two groups. …”
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Deep learning approach for automated hMPV classification by Sivarama Prasad Tera, Ravikumar Chinthaginjala, Irum Shahzadi, Priya Natha, Safia Obaidur Rab

“…To mitigate this, the framework incorporates advanced techniques such as data augmentation, weighted loss functions, and dropout regularization, which help to balance the dataset, improve model robustness, and enhance classification accuracy. …”
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Optical coherence tomography in preclinical diagnosis of optic nerve disk changes after chemotherapy in children with retinoblastoma by S. V. Saakyan, E. B. Myakoshina, V. G. Polyakov, T. L. Ushakova, D. M. Ismailova

“…Preclinical diagnostics of optic disc pathology with the help of OCT allows predicting visual functions in children with RB at its early stages and developing a differentiated approach to the choice of RB treatment.…”
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Oxidative stress gene expression in ulcerative colitis: implications for colon cancer biomarker discovery by Ting Yan, Ting Su, Miaomiao Zhu, Qiyuan Qing, Binjie Huang, Jun Liu, Tenghui Ma

“…Furthermore, we utilized the STRING database and Cytoscape to establish a protein–protein interaction (PPI) network and constructed an mRNA-transcription factor (TF) and mRNA-miRNA interaction networks. The molecular functions and signaling pathways enriched in OXSRDEGs were determined. …”
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The lncRNA MIR181A1HG in extracellular vesicles derived from highly metastatic colorectal cancer cells promotes liver metastasis by remodeling the extracellular matrix and recruiti... by Yichao Gu, Yushuai Mi, Yifan Cao, Kuan Yu, Zihao Zhang, Peng Lian, Dawei Li, Jing Qin, Senlin Zhao

“…Additionally, we verified that HNRNPA2B1 mediated the packaging of MIR181A1HG into CRC cell-derived EVs, which in turn functioned as a ceRNA by sponging miR373-3p to activate HSCs via the TGFβRII/Smad2/3 signaling pathway. …”
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Mathematical modeling of heat and mass transfer processes in a reciprocating engine of a vehicle with a hybrid powertrain by Fedіr Abramchuk, Vitaliy Krivda, Olha Sakno, Valentyna Olishevska, Kostyantyn Kornilenko, Olena Sakno

“…Automotive transport plays a crucial role in the functioning and development of any country's economy. …”
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