Senkyunolide H reverses depression-induced breast cancer progression by regulating CXCR2 by Yingchao Wu, Jiaqi Cui, Liushan Chen, Jieting Chen, Junfeng Huang, Congwen Yang, Yuqi Liang, Qianjun Chen, Qian Zuo

“…Methods Transcriptomic analysis was conducted to identify and functionally annotate genes with differential expression in breast cancer patients exhibiting depressive symptoms. …”
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Method of investigating thermal fluctuation processes in problems of diagnostics and prediction of insulating materials by Marina N. Dubyago, Nikolay K. Poluyanovich, Vyacheslav Kh. Pshikhopov

“…At that, different charging modes of operation and functions of the cable current variation are investigated. …”
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PathNetDRP: a novel biomarker discovery framework using pathway and protein–protein interaction networks for immune checkpoint inhibitor response prediction by Dohee Lee, Jaegyoon Ahn, Jonghwan Choi

“…Given these limitations, we developed PathNetDRP, a framework that integrates biological pathways, protein-protein interaction networks, and machine learning to identify functionally relevant biomarkers for ICI response prediction. …”
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Bioinformatics analysis and preliminary validation of autophagy-related genes in asthma disease by Bo Sun, Huiman Huang, Ran An, Bing Wei, Xiaozhe Yue

“…The present study provides a new insight that autophagy dysregulation exists in asthma and may be involved in the etiology of asthma by participating in multiple pathways and biological functions. Autophagy-related genes in asthma may be valuable biomarkers for diagnosis and prognosis, and they may be developed as clinical therapeutic targets in the future.…”
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Bridge Damage Localization Through Response Reconstruction with Multiple BP-ANNs Under Vehicular Loading by Xuzhao Lu, Chenxi Wei, Limin Sun, Wei Zhang

“…Compared to existing research, our method does not necessitate prior knowledge of factors such as mode shape functions, traffic conditions, or the constraint of inspecting with a single vehicle. …”
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Single-cell transcriptome atlas reveals mitophagy dynamics in acute chemical injury model and the role of MSCs transplantation by Sang Luo, Fang Wu, Xiaojun Yang

“…Abstract Background and purpose Mitochondrial autophagy, also referred to as mitophagy, clears damaged mitochondria and has dual functions in disease development and liver homeostasis in response to liver pathologies. …”
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An ultrasensitive electrochemical immunosensor for CA72-4 based on a signal amplification strategy of MoS2 nanoflower-supported Au nanoparticles by Qinghua Yan, Ruixue Wu, Hongli Chen, Wenbin Nan

“…Modification of noble metal nanoparticles on transition metal dichalcogenides can significantly enhance functions, such as electron transport. Molybdenum disulfide gold nanoparticles nanocomposites (MoS2-Au NPs) were prepared in this study and a series of characterization studies were carried out. …”
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Mutation- and Transcription-Driven Omic Burden of Daptomycin/Dalbavancin-R and Glycopeptide-RS Fitness Costs in High-Risk MRSA: A Nexus in Antimicrobial Resistance Mechanisms—Genom... by Eleonora Chines, Gaia Vertillo Aluisio, Maria Lina Mezzatesta, Maria Santagati, Viviana Cafiso

“…Results: Moderate impact nsSNPs were identified in EGs related to vital cellular functions and VGs. Comparative EG transcriptomics revealed differential expressions and key dysregulations—via asRNAs—prevalently affecting the protein synthesis and cell-envelope EG clusters, as well as the VG cluster. …”
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Gyro-System for Guidance with Magnetically Suspended Gyroscope, Using Control Laws Based on Dynamic Inversion by Romulus Lungu, Constantin-Adrian Mihai, Alexandru-Nicolae Tudosie

“…For this purpose, a differential geometry method, based on the use of the output vector’s gradient with respect to the nonlinear state functions, i.e., based on Lie derivatives, is used. …”
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Differences of interference myogram patterns from forearm muscles at different variants of the hand grip by E. A. Eliseichev, A. A. Tyaptin, R. M. Zhilin, P. S. Vorobyev, I. S. Blinov

“…Most modern bioprostheses use two sensors located on the flexor and extensor muscles of the hand and fingers to register muscle activity, which severely limits the functionality of the device and complicates switching between grips. …”
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TEMPERATURE DISTRIBUTION IN MULTILAYER METAL-CERAMIC COATINGS UNDER NONSTATIONARY THERMAL EFFECTS by V. M. Samoilenko, Y. V. Petrov, O. A. Ratenko

“…Making calculations according to the proposed method it is possible to predict the performance of turbine blades, having the information about the intensity of phase transformations in the alloy and the temperature transitions in the process of gas turbine engine functioning (using the data of the on-board parameters monitoring and recording systems).…”
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Existence and Uniqueness of Fixed-Point Results in Non-Solid <i>C</i>^⋆-Algebra-Valued Bipolar <i>b</i>-Metric Spaces by Annel Thembinkosi Bokodisa, Maggie Aphane

“…We define and analyze <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>(</mo><msub><mi>F</mi><mi mathvariant="script">H</mi></msub><mo>−</mo><msub><mi>G</mi><mi mathvariant="script">H</mi></msub><mo>)</mo></mrow></semantics></math></inline-formula>-contractions, utilizing positive monotone functions to extend classical contraction principles. …”
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Intervention of machine learning in bladder cancer research using multi-omics datasets: systematic review on biomarker identification by Blessy Kiruba, P. S. Athul Narayan, Badhari Raj, S. Rohieth Raj, Sam George Mathew, Sudhakaran Sajitha Lulu, Vino Sundararajan

“…Integrated models combining computational techniques with large multi-omics datasets have gained significant attention, enabling the identification of significant BC biomarkers that include genes coding for diverse cellular functions, differentially expressed genes, proteins, and metabolites. …”
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On the conundrum of cognitive impairment due to depressive disorder in older patients. by Claudia E Lanza, Karolina Sejunaite, Charlotte Steindel, Ingo Scholz, Matthias W Riepe

“…With case-control matching of HC and DD-BM- we find that executive functions are impaired in about one out of three and delayed recall in about two out of three patients with DD.…”
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A scoping review of measurement of violence against women and disability. by Sarah R Meyer, Heidi Stöckl, Cecilia Vorfeld, Kaloyan Kamenov, Claudia García-Moreno

“…In terms of measurement of disability, we found that amongst the included manuscripts and reports, n = 75 utilized measures of functioning limitations (n = 20 of these were Washington Group questions), n = 15 utilized a single question approach and n = 67 defined participants in the research as having a disability based on a diagnosis or self-report of a health condition or impairment.…”
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Change in the plasma proteome associated with canine cognitive dysfunction syndrome (CCDS) in Thailand by Sataporn Phochantachinda, Boonrat Chantong, Onrapak Reamtong, Duangthip Chatchaisak

“…The nano-LC-MS/MS data revealed that the predictive underlying mechanism of CCDS was the co-occurrence of inflammation-mediated acute phase response proteins and complement and coagulation cascades that partly functioned by apolipoproteins and lipid metabolism. …”
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DEHP-Induced Glioblastoma in Zebrafish Is Associated with Circadian Dysregulation of PER3 by Shuhui Men, Jiayun Xu, Zhanhong Yang, Zhenguang Yan

“…Long-term exposure to DEHP can cause endocrine disruption and interfere with the organism’s normal functioning. In order to explore the potential effects of DEHP on the development of biological brain tissues, this study used bioinformatics analysis to confirm the diagnostic and prognostic value of PER3 in gliomas and further validated the neurotoxicity of DEHP using methods such as behavioral experiments and molecular biology in zebrafish. …”
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Cognitive decline gap between male and female in Indian context: Examining the contribution of underlying factors using non-linear decomposition analysis by Subhadeep Saha, Priya Das, Tanu Das, Partha Das, Tamal Basu Roy

“…It is an alarming issue with the increasing age of individuals and sometimes it hinders the smooth functioning of daily activities in life. Affirmations from both developed and developing countries manifest that older people are at risk of cognitive decline; however, the study about male-female differential remained scanty. …”
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The nucleoid protein Dps binds genomic DNA of Escherichia coli in a non-random manner. by S S Antipov, M N Tutukina, E V Preobrazhenskaya, F A Kondrashov, M V Patrushev, S V Toshchakov, I Dominova, U S Shvyreva, V V Vrublevskaya, O S Morenkov, N A Sukharicheva, V V Panyukov, O N Ozoline

“…Dps is a multifunctional homododecameric protein that oxidizes Fe2+ ions accumulating them in the form of Fe2O3 within its protein cavity, interacts with DNA tightly condensing bacterial nucleoid upon starvation and performs some other functions. During the last two decades from discovery of this protein, its ferroxidase activity became rather well studied, but the mechanism of Dps interaction with DNA still remains enigmatic. …”
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Mapping Hsp104 interactions using cross‐linking mass spectrometry by Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak

“…Recent cryo‐EM structures of AAA+ molecular machines have uncovered nuanced changes in their conformation that underlie their specialized functions. Structural knowledge of these molecular machines in complex with substrates begins to explain their mechanism of activity. …”
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