Well-posedness of the difference schemes of the high order of accuracy for elliptic equations

“…In the present paper we consider the high order of accuracy two-step difference schemes generated by an exact difference scheme or by Taylor's decomposition on three points for the approximate solutions of this differential equation. The well-posedness of these difference schemes in the difference analogy of the smooth functions is obtained. …”
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Methods for Applying Matrices when Creating Models of Group Pursuit by A. A. Dubanov

“…The listed processes were illustrated by functions in the given coordinate systems and animation. …”
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Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study by Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari

“…Abstract Background MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally and show differential expression in various tissues with aging phenotypes. …”
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Activated cancer-associated fibroblasts correlate with poor survival and decreased lymphocyte infiltration in infiltrative type distal cholangiocarcinoma by Dae Hyun Lim, Yung-Kyun Noh, Byoung Kwan Son, Dong-Hoon Kim, Kyueng-Whan Min, Seoung Wan Chae, Hyung Suk Kim, Mi Jung Kwon, Jung Soo Pyo, Yoonhyeong Byun

“…The presence of aCAFs significantly correlated with poor survival, advanced T and N stages, infiltrative growth pattern, lymphatic/perineural/adjacent organ invasion, and decreased tumor-infiltrating lymphocytes. aCAFs-related genes were associated with immune system functions, G protein-coupled receptor signaling, and metabolic conditions (diabetes, obesity, and abnormal C-peptide levels). …”
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Exploration of the mechanism of 5-Methylcytosine promoting the progression of hepatocellular carcinoma by Qiyao Zhang, Zhen Cao, Yuting He, Ziwen Liu, Wenzhi Guo

“…5-Methylcytosine (m5C) is a ubiquitous RNA modification that is closely related to various cellular functions. However, no studies have comprehensively demonstrated the role of m5C in hepatocellular carcinoma (HCC) progression. …”
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Effects of Rumen-Protected Methionine on Meat Quality, Fatty Acid Composition, Volatile Flavor Compounds and Transcriptomics of <i>Longissimus lumborum</i> of Yak (<i>Bos grunniens... by Xia Wu, Zizhen Zuo, Jiajia Li, Jianhui Fu, Jincheng Zhong, Hui Wang, Haitao Shi, Yanling Huang, Haibo Wang

“…Gene ontology enrichment analysis revealed significant differentially expressed genes enrichment in biological processes, cellular components, and molecular functions across RPM5, RPM10, and RPM15 groups compared to the CON. …”
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Validity of the test for attentional performance in neurological post-COVID condition by Susan Seibert, Irina Eckert, Catherine N. Widmann, Taraneh Ebrahimi, Fabian Bösl, Christiana Franke, Harald Prüss, Joachim L. Schultze, Gabor C. Petzold, Omid Shirvani

“…Abstract Neurological post-COVID condition (PCC) often involves attentional deficits that impact daily functioning. Traditional paper-based tests, like the Trail-Making Test (TMT), may inadequately capture these impairments due to their short duration and dependence on numerical and alphabetic sequencing. …”
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Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure by Linna Zhao, Juanjuan Zhang, Juanjuan Zhang, Qiuhang Song, Cheng Dai, Yiping Qin, Aiying Li, Aiying Li

“…The predictive model based on these four DRGs effectively differentiated between HF patients and healthy individuals, which was validated in the experiment. …”
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Dynamic deployment of H2A.Z positive nucleosome mediated transcriptomic plasticity within vascular smooth muscle cell by Chao Yu, Jiaxin Huang, Yan Wang, Jia Song, Wei Shen

“…Abstract Background To maintain homeostasis in the mature human body, certain differentiated cells adopted high plasticity to refine their cellular functions. …”
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Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33 by Katelyn E. Connelly, Katherine Hullin, Ehssan Abdolalizadeh, Jun Zhong, Daina Eiser, Aidan O’Brien, Irene Collins, Sudipto Das, Gerard Duncan, Pancreatic Cancer Cohort Consortium, Pancreatic Cancer Case-Control Consortium, Stephen J. Chanock, Rachael Z. Stolzenberg-Solomon, Alison P. Klein, Brian M. Wolpin, Jason W. Hoskins, Thorkell Andresson, Jill P. Smith, Laufey T. Amundadottir

“…Here, we fine-map and functionally characterize a common PDAC risk signal at chr1p36.33 (tagged by rs13303010) identified through a genome wide association study (GWAS). …”
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Immune Basis of Therapeutic Effects of <i>Solanum tuberosum</i> L. Polysaccharide on Chronic Peptic Ulcer Healing by Evgenii Generalov, Denis Laryushkin, Kristina Kritskaya, Nina Kulchenko, Arkady Sinitsyn, Leonid Yakovenko, Liubov Generalova, Nikolay Belostotsky

“…<b>Conclusions</b>: Intravenous administration of STP leads to the restoration of functionality and effective tissue regeneration. The antiulcer activity of STP is based on the regulation of the pro- and anti-inflammatory balance.…”
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Mathematical modeling of sorption isotherms and the thermodynamic properties of vacuum-dried and freeze-dried Barhi dates by Mohamed Fikry, Saleh Al-Ghamdi, Bandar Alfaifi, Mansour N. Ibrahim, Nashi Alqahtani, Muhammad Umar, Kitipong Assatarakul

“…These thermodynamic parameters were effectively modeled as functions of Xe, indicating that both adsorption and desorption were nonspontaneous processes. …”
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Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity by Ying Zhang, Aiting Wang, Wei Zhao, Jia’an Qin, Yu Zhang, Bing Liu, Chengcheng Yao, Jianglan Long, Mingxia Yuan, Dan Yan

“…In conclusion, we demonstrated that upregulated SIgA, which could be regulated by succinate, was functionally involved in metformin response through its influence on immune cell-mediated inflammation and insulin resistance. …”
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Single cell atlas of canine natural killer cells identifies distinct circulating and tissue resident gene profiles by Aryana M. Razmara, Marshall Lammers, Sean J. Judge, William J. Murphy, Cameron E. Gaskill, William T.N. Culp, Alicia A. Gingrich, Zachary S. Morris, Robert B. Rebhun, C. Titus Brown, David M. Vail, Michael S. Kent, Robert J. Canter

“…IntroductionNatural killer (NK) cells in mice and humans are key effectors of the innate immune system with complex immunoregulatory functions, and diverse subsets have been identified with distinct characteristics and roles. …”
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Metabolomics analysis of extracellular vesicles derived from bovine colostrum and mature milk by Sitong Zhang, Xipeng Sun, Yameng Zhang, Rong Huang, Wenyou Situ, Huaxi Yi, Lingjun Tong

“…This study aims to explore the metabolomic profiles of C-mEVs and M-mEVs to uncover their molecular characteristics and potential biological functions. The mEVs were purified from both bovine colostrum and mature milk using ultracentrifugation combined with size exclusion chromatography. …”
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A Transition to Discharge Program for the Reduction of Early Readmission in a Mental Health Inpatient Unit: Study Protocol by Vera Carbonell-Aranda, Yaiza García-Illanes, María Traverso-Rodríguez, Antonio Bordallo-Aragón, Berta Moreno-Kustner, José Guzmán-Parra, Jesús Herrera-Imbroda

“…Success will also be measured through pre- and post-assessments of the recovery, functionality, subjective well-being, social support, and treatment satisfaction of those participating in the psychotherapeutic group. …”
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Effects of Pregelatinization on the Physicochemical Properties of Corn Grits and the Quality of Cooked Waxy Corn Wrapped in Plant Leaves by Yi Wang, Ruixuan Li, Yijiao Yan, Wanyi Niu, Yue Wang, Mingyi Shen, Ruifang Wang, Li Cheng

“…The findings demonstrate that pregelatinization optimizes starch functionality, mitigates retrogradation, and improves the overall quality of traditional corn-based foods, providing a practical approach for industrial applications.…”
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The path to teaching Excellence: Examining self-efficacy of pre-service teachers during school internship programs in Indonesia by Opik Abdurrahman Taufik, Soeharto Soeharto, Abdul Kadir Ahmad, Suprapto, Sumarni, Nunu Ahmad An-Nahidl, Onok Yayang Pamungkas, Siti Mariah, Dinar Westri Andini, Pramudya Cahyandaru

“…Findings also reveal that the Instructional Self-Efficacy (ISE) domain showed the highest self-efficacy scores, while the Efficacy in Creating a Positive School Atmosphere (ECPSA) domain recorded the lowest. Additionally, Differential Item Functioning (DIF) analysis revealed negligible gender bias for most items, with one item (ECPSA5) demonstrating moderate to large DIF. …”
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What about the donor site morbidity – how invasive is the free latissimus dorsi flap? by Nikolaus Wachtel, Riccardo E. Giunta, Marc Hellweg, Maximilian Hirschmann, Constanze Kuhlmann, Nicholas Moellhoff, Denis Ehrl

“…Moreover, LDM flap harvest caused a significant reduction in strength in the glenohumeral joint in all functions of the LDM that were assessed, ranging from 9.0% to 13.8%. …”
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Exosomes derived from apical papilla stem cells improve NASH by regulating fatty acid metabolism and reducing inflammation by Yifei Nie, Wenqing Meng, Duanqin Liu, Ziqing Yang, Wenhao Wang, Huiping Ren, Kai Mao, Weipeng Lan, Chuanhua Li, Zhifeng Wang, Jing Lan

“…Exosomes derived from stem cells have emerged as safer alternatives that retain comparable physiological functions. This study explores the therapeutic potential of exosomes sourced from SCAPs in the treatment of non-alcoholic steatohepatitis (NASH). …”
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