Interictal functional connectivity of human epileptic networks assessed by intracerebral EEG and BOLD signal fluctuations. by Gaelle Bettus, Jean-Philippe Ranjeva, Fabrice Wendling, Christian G Bénar, Sylviane Confort-Gouny, Jean Régis, Patrick Chauvel, Patrick J Cozzone, Louis Lemieux, Fabrice Bartolomei, Maxime Guye

“…We quantified functional connectivity using non-linear measures of cross-correlation between signals obtained from intracerebral EEG (iEEG) and resting-state functional MRI (fMRI) in 5 patients suffering from intractable temporal lobe epilepsy (TLE). …”
Get full text

Preparation and Characterization of Functionalized Cellulose Nanomaterials (CNMs) for Pb(II) Ions Removal from Wastewater by Hizkeal Tsade, Sisay Tadesse Anshebo, Fedlu Kedir Sabir

Get full text

Mature murine supraspinatus tendons demonstrate regional differences in multiscale structure, function and gene expression. by Michael S DiStefano, Stephanie N Weiss, Courtney A Nuss, Rebecca L Betts, Biao Han, Andrew F Kuntz, Louis J Soslowsky

“…Therefore, the purpose of this study was to elucidate site-specific hierarchical structure, function, and gene expression differences in mouse supraspinatus tendons. …”
Get full text

GeneCOCOA: Detecting context-specific functions of individual genes using co-expression data. by Simonida Zehr, Sebastian Wolf, Thomas Oellerich, Matthias S Leisegang, Ralf P Brandes, Marcel H Schulz, Timothy Warwick

“…This approach does not cater to analyses focused on a single gene-of-interest, particularly when the gene lacks prior functional characterization. To address this, we formulated GeneCOCOA, a method which utilizes context-specific gene co-expression and curated functional gene sets, but focuses on a user-supplied gene-of-interest (GOI). …”
Get full text

Slice holomorphic functions in the unit ball: boundedness of $L$-index in a direction and related properties by A. I. Bandura, T. M. Salo, O. B. Skaskiv

“…It is criterion useful in applications to differential equations. We introduce a concept of function having bounded value $L$-distribution in direction for the slice holomorphic functions in the unit ball. …”
Get full text

Characteristics of hypertension and its impact on cognitive functions in older adults: a cross-sectional study by Nivedita Parandiyal, Porimita Chutia, Shashank Saurabh Sinha, Pratyaksha Pandit, Naif Ali Majrashi, Naseem Qureshi, Shailendra Mohan Tripathi, Shailendra Mohan Tripathi

“…Among the individual cognitive domains, a significant difference was observed in attention and fluency domains of cognitive function based on HTN status (p > 0.05) but differential effect on cognitive domains was not seen with the duration of HTN. …”
Get full text

IAPP blocks anti-breast cancer function of CD8+T cells via targeting cuproptosis by Dandan Guo, Dandan Guo, Zhijian Huang, Qianqian Wang, Qianqian Wang, Wei Chen, Wei Chen, Yu Huang, Yu Huang, Xinhao Sun, Jian Chen, Shuying Feng, Shuying Feng

“…Thereby downregulation of IAPP reduced cuprotosis of CD8+T or Her2-CAR-T cells to promote the anti-BRCA function both in vitro and in vivo.ConclusionOur research had clarified the function and mechanism of IAPP in CD8+T cells, providing new ideas for improving the diagnosis and treatment of BRCA.…”
Get full text

RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification. by Aneeshkumar G Arimbasseri, Nathan H Blewett, James R Iben, Tek N Lamichhane, Vera Cherkasova, Markus Hafner, Richard J Maraia

Get full text

Expansins in Salt and Drought Stress Adaptation: From Genome-Wide Identification to Functional Characterisation in Crops by Siarhei A. Dabravolski, Stanislav V. Isayenkov

“…This manuscript explores the functions of expansins in salt and drought stress responses across multiple plant species, highlighting their involvement in cell wall loosening, transcriptional regulation, ion and osmotic homeostasis, and phytohormone signalling. …”
Get full text

The RhoGEF trio functions in sculpting class specific dendrite morphogenesis in Drosophila sensory neurons. by Srividya Chandramouli Iyer, Dennis Wang, Dennis Wang, Eswar Prasad R Iyer, Sarah A Trunnell, Ramakrishna Meduri, Riaz Shinwari, Mikolaj J Sulkowski, Daniel N Cox

“…Trio is expressed in all da neuron subclasses and loss-of-function analyses indicate that Trio functions cell-autonomously in promoting dendritic branching, field coverage, and refining dendritic outgrowth in various da neuron subtypes. …”
Get full text

Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer by Guojing Zhang, Xiaoyan Wu, Hongmin Fu, Daqing Sun

Get full text

Opinion dynamics of leaders and followers with multi-criteria influence functions for urban transport project application by Julius Selle, Rica Villarosa, Charldy Wenceslao, Dharyll Prince Abellana, Rhoda Namoco, John Kevin Padro, Lanndon Ocampo

Get full text

Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences. by Lingyu Zhan, Jiajin Li, Brandon Jew, Jae Hoon Sul

“…Careful examination using NFTs revealed one significantly associated gene, ANKRD13D. To identify functional associations, we integrated bulk RNA-Seq data from over 600 brain tissues and found two endocytic expression genes (eGenes), HLA-A and SLC26A7, that displayed significant influences on their gene expressions. …”
Get full text

Seminal plasma proteomics of asymptomatic COVID-19 patients reveals disruption of male reproductive function by Jialyu Huang, Yufang Su, Jiawei Wang, Zheng Fang, Yiwei Zhang, Hong Chen, Xinxia Wan, Yuanhuan Xiong, Ning Song, Houyang Chen, Xingwu Wu

“…Abstract Background A considerable proportion of males suffer from asymptomatic SARS-CoV-2 infection, while the effect on reproductive function and underlying pathomechanisms remain unclear. …”
Get full text

Function-preserving Surgical Management of Benign Peripheral Nerve Sheath Tumours: A Case Series by Ansar Pullampara Pookunju, Aisel Paul, Mariya Jacob, Manoj Parameswaran

“…Peripheral Nerve Sheath Tumours (PNSTs) present a unique surgical challenge, requiring a balance between complete tumour removal and preservation of neurological function. Function-preserving excision techniques offer promising solutions, but their implementation demands careful evaluation and surgical expertise. …”
Get full text

A systematic review and functional in-silico analysis of genes and variants associated with amyotrophic lateral sclerosis by Carlos A. Arreola-Aldape, Carlos A. Arreola-Aldape, Carlos A. Arreola-Aldape, Jose A. Moran-Guerrero, Jose A. Moran-Guerrero, Guillermo K. Pons-Monnier, Guillermo K. Pons-Monnier, Rogelio E. Flores-Salcido, Rogelio E. Flores-Salcido, Emmanuel Martinez-Ledesma, Emmanuel Martinez-Ledesma, Luis M. Ruiz-Manriquez, Luis M. Ruiz-Manriquez, K. Rebeca Razo-Alvarez, K. Rebeca Razo-Alvarez, Daniela Mares-Custodio, Daniela Mares-Custodio, Pablo J. Avalos-Montes, Pablo J. Avalos-Montes, Jose A. Figueroa-Sanchez, Jose A. Figueroa-Sanchez, Rocio Ortiz-Lopez, Rocio Ortiz-Lopez, Rocio Ortiz-Lopez, Hector R. Martínez, Hector R. Martínez, Raquel Cuevas-Diaz Duran, Raquel Cuevas-Diaz Duran

Get full text

Effect of curcumin incorporation on the structural and functional properties of oleogels structured with rice bran or carnauba wax by Md Jannatul Ferdaus, Jabarius Allah Malik Jones, Roberta Claro da Silva

“…These findings demonstrate that oleogels can function as structurally stable carriers for curcumin while maintaining desirable physical properties for food applications. …”
Get full text

Compositional and functional gut microbiota alterations in mild cognitive impairment: links to Alzheimer’s disease pathology by Kang-Chen Fan, Chen-Ching Lin, Yen-Ling Chiu, Seong-Ho Koh, Yi-Chien Liu, Yi-Fang Chuang

“…Notably, species within the same genera, such as Bacteroides and Ruminococcus, showed opposing effects, while Akkermansia muciniphila correlated with reduced amyloid burden, suggesting a protective role. Functional profiling revealed microbial pathways contributing to energy metabolism and neuroinflammation, mediating the relationship between gut microbes and brain health. …”
Get full text

The association between physical activity and lung function in adolescents: a cross-sectional NHANES study by Xiaoyuan Chen, Jinhai Ma, Linghua Dong, Yan Chen, Keke Chen

“…Linear regression analyses were employed to examine the relationship between PA duration and lung function, adjusting for potential confounders. The sample was stratified by intensity of PA (low, moderate, and high) to assess differential impacts on lung function.ResultsThe analysis revealed significant improvements in lung function with increased PA duration, with high-intensity PA showing the most pronounced effects. …”
Get full text

The effects of dietary fat on gut microbial composition and function in a mouse model of ovarian cancer by Mariam M. AlHilli, Naseer Sangwan, Alex Myers, Surabhi Tewari, Daniel J. Lindner, Gail A. M. Cresci, Ofer Reizes

“…Stool samples were collected at the time of euthanasia and analyzed by 16SrRNA sequencing and shotgun metagenomic sequencing was performed to identify differential microbial taxonomic composition and metabolic function. …”
Get full text