Landscape Scene Sequences of Park View Elements Facilitate Walking, Jogging, and Running: Evidence from 3 Parks in Shanghai by Nan Wang, Qiongruo Wang, Weixuan Wei, Guanpeng Liu, Ming Liu

“…This study breaks through the limitations of traditional subjective evaluations by coupling objective physiological data with spatial elements, offering novel insights for optimizing the exercise functionality of urban green spaces.…”
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Sex‐dependent and sex‐independent regulatory systems of size variation in natural populations by Hirokazu Okada, Ryohei Yagi, Vincent Gardeux, Bart Deplancke, Ernst Hafen

“…In contrast, we find that between‐line size variation is largely regulated by genes with a diverse range of cellular functions, most of which have never been implicated in growth. …”
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Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice by Jenny Chen, Phoebe R Richardson, Christopher Kirby, Sean R Eddy, Hopi E Hoekstra

“…We identify four cell types that are differentially abundant across species, two of which may account for species differences in parental care behavior based on known functions of these cell types. …”
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CARD8 inflammasome activation during HIV-1 cell-to-cell transmission by Jessie Kulsuptrakul, Michael Emerman, Patrick S Mitchell

“…CARD8 harbors a motif in its N-terminus that functions as a HIV protease substrate mimic, permitting innate immune recognition of HIV-1 protease activity, which when cleaved by HIV protease triggers CARD8 inflammasome activation. …”
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Tailoring Silk Sericin Grafting: Comparing One‐Step and Two‐Step Approaches for PNIPAM/PAMPS Block Nanoparticles by Ionut‐Cristian Radu, Derniza‐Elena Cozorici, Erika Blanzeanu, Andreea Vadureanu, Cristina Stavarache, Eugenia Tanasa, Horia Iovu, Catalin Zaharia

“…The integration of synthetic polymers with natural proteins such as silk sericin enhances the functionality and stability of these nanocarriers, making them suitable for targeted and controlled drug release. …”
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Tracking the genome-wide occupancy of Arabidopsis LEAFY COTYLEDON1 in endosperm development by Jingpu Song, Xin Xie, Ioannis Mavraganis, Bianyun Yu, Wenyun Shen, Hui Yang, Daoquan Xiang, Yangdou Wei, Yuhai Cui, Jitao Zou

“…LEC1 expression in the endosperm is detectable within a day after fertilization, yet its specific regulatory networks and developmental functions in this tissue remain unclear. To address this, we employed a modified INTACT system to isolate endosperm nuclei and performed ChIP-seq to map the genome-wide binding profile of LEC1 in developing endosperm. …”
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Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization by Megan V Cannon, Herman HW Silljé, Jürgen WA Sijbesma, Inge Vreeswijk‐Baudoin, Jolita Ciapaite, Bart van der Sluis, Jan van Deursen, Gustavo JJ Silva, Leon J de Windt, Jan‐Åke Gustafsson, Pim van der Harst, Wiek H van Gilst, Rudolf A de Boer

“…Functionally, LXRα overexpression in isolated cardiomyocytes and murine hearts markedly enhanced the capacity for myocardial glucose uptake following hypertrophic stress. …”
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Understanding the role of sex on outcomes for the cancer patient undergoing treatment with immune checkpoint inhibitors: a scoping review protocol by Grace Lu-Yao, Jennifer M Johnson, Amy L Shaver, Nikita Nikita, Swapnil Sharma, Daniel S Lefler, Atrayee Basu-Mallick, Meghan L Butryn

“…Sex plays an important role in both the development of cancer as well as the functioning of the immune system. Though a difference in response to immune therapy is emerging between men and women it is unclear how this difference affects cancer outcomes and what the potential underlying mechanisms are for those effects. …”
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Radiation-induced effects on commercial 3D printing materials exposed to high x-ray doses by L Sostero, M Ferrari, D Pagano, S Pandini, C Pasini, A Boukenter, A Morana, S Girard

“…This adaptable technique has garnered considerable interest for the development of components functioning under severe radiation environments, including particle accelerators and nuclear reactors. …”
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RBPMS inhibits bladder cancer metastasis by downregulating MYC pathway through alternative splicing of ANKRD10 by Jingtian Yu, Liang Chen, Gang Wang, Kaiyu Qian, Hong Weng, Zhonghua Yang, Hang Zheng, Mengxin Lu

“…RBPMS depletion in BLCA cells resulted in AS of ANKRD10 and increased ANKRD10-2 expression. ANKRD10-2 functioned as a transcriptional co-activator of MYC proteins, thereby augmenting their transcriptional activity. …”
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Genomic Landscape and Potential Regulation of RNA Editing in Drug Resistance by Xu Zhou, Ramkrishna Mitra, Fei Hou, Shunheng Zhou, Lihong Wang, Wei Jiang

“…In addition, it is determined that the functions of genes enriched with DESs are associated with drug resistance, such as apoptosis, drug metabolism, and DNA synthesis involved in DNA repair. …”
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Analysis of the development of a vocational educational institutions network in the Sverdlovsk region in the 1920s–1950s by means of using database technology and GIS by S. L. Razinkov

“…The evolution of the regional network of vocational educational institutions is analyzed mainly in five time points: 1) 1922–1923 — the beginning of the formation of the Soviet model of vocational education; 2) 1932–1933 — an intensive expansion of the departmental network of vocational education institutions during; 3) 1940 – early 1941 — the creation of a system of State labor reserves as a single nationwide system for the training of qualified workers; 4) 1948 — the functioning of the network of educational institutions at the maximum level of quantitative indicators as a result of its extensive development; 5) 1958 — reforming the system of vocational education in order to differentiate and deepen the level of training of workers. …”
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Alginate Oligosaccharide Coordinately Modulates Endogenous Phytohormone Profiles to Enhance Tomato Growth by Yun Li, Jianxia Wang, Kai Fan, Lingru Guo, Leiping Hou, Yanxiu Miao, Meihua Sun, Yaling Li, Longqiang Bai

“…Alginate oligosaccharides (AOSs) have been shown to be effective in enhancing crop growth. However, their functions in horticulture crops and growth-promoting mechanisms remain insufficiently characterized. …”
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Strategies to Improve Hydrolysis Efficiency of Fish Skin Collagen: Study on ACE Inhibitory Activity and Fibroblast Proliferation Activity by Cuihua Chang, Yuzhou Ma, Yanjun Yang, Yujie Su, Luping Gu, Junhua Li

“…Collagen peptides play a crucial role in promoting skin elasticity and enhancing joint health, with potential functions to be explored. Enzyme hydrolysis is crucial for the molecular weight and sequence of peptides, influencing the bio-activity. …”
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Global retention models in reversed-phase liquid chromatography. A tutorial by P. Peiró-Vila, J.R. Torres-Lapasió, M.C. García-Alvarez-Coque

“…To illustrate its practical application, an example is presented involving a large set of diverse compounds, using a MATLAB set of functions created for this tutorial to showcase the implementation of global retention modelling.…”
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Cross-cultural measurement invariance of the BFI-15p in university students from Argentina, Spain, and Peru by César Merino-Soto, Sergio Dominguez-Lara, Lucas Marcelo Rodriguez, Guillermo M. Chans, Manuel Marti-Vilar

“…Omega reliability varied across country groups but was predominantly acceptable for three-item subscales (approximately 0.60). Differential item functioning (DIF) by sex within each country was predominantly negligible. …”
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Designs of NKG2D-based immunotherapeutics for cancer by Jianfeng Han, Youwei Wang, Godfrey Chi-Fung Chan, Godfrey Chi-Fung Chan, Wing Keung Chan

“…Despite being genomically conserved between human and mouse, NKG2D transcripts have splice variants that can differentiate the two. hNKG2D or mNKG2D (both long and short transcripts) interacts with DAP10 only in human but DAP10/12 in mouse, switching on different effector functions such as IFN-γ production and cytotoxicity. …”
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Evaluating Problematic Smartphone Use Among Chinese Primary School Students Using SABAS: An IRT and Network Analysis by Siyang Liu, Qian Chen, Jiayang Li, Yimeng Zhu, Xiaorong Guo, Xin Zhao

“…SABAS was assessed using Item Response Theory (IRT) for factor structure, item parameters, cut‐off scores, and reliability, while Differential Item Functioning (DIF) detected gender biases. …”
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Solving Continuous Models with Dependent Uncertainty: A Computational Approach by J.-C. Cortés, J.-V. Romero, M.-D. Roselló, Francisco-J. Santonja, Rafael-J. Villanueva

“…Theoretically, Galerkin projection-based methods take advantage of orthogonality with the aim of simplifying the involved computations when solving r.o.d.e.’s, which means to compute both the solution and its main statistical functions such as the expectation and the standard deviation. …”
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A Chatbot-Based Version of the World Health Organization–Validated Self-Help Plus Intervention for Stress Management: Co-Design and Usability Testing by Valentina Fietta, Silvia Rizzi, Chiara De Luca, Lorenzo Gios, Maria Chiara Pavesi, Silvia Gabrielli, Merylin Monaro, Stefano Forti

“…Prototypes were evaluated by 13 domain experts from diverse sectors and 15 participants from the target groups to assess usability, attractiveness, and functionality through semantic differential scales, the User Version of the Mobile Application Rating Scale questionnaire, and semistructured interviews. …”
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