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15001
Impact of the alkaline volatile trimethylamine on the physiology of Streptomyces venezuelae: an integrated transcriptomic and metabolomics study
Published 2025-07-01“…ABSTRACT Streptomyces bacteria use volatile compounds for a range of functions, including communication and to kill competing species. …”
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15002
Exercise-related immune gene signature for hepatocellular carcinoma: machine learning and multi-omics analysis
Published 2025-06-01“…Furthermore, we conducted molecular subtyping, qRT-PCR, biological functions, immune infiltration, drug sensitivity, and single cell analyses on EIGPS.ResultsUsing WGCNA, differential gene expression analysis, and CIBERSORT, 59 EIGs were identified, of which 54 were associated with prognosis. …”
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15003
Modern View on the Etiology and Methods of Treatment of Bruxism: а Review
Published 2024-12-01“…Timely diagnosis and treatment of bruxism is an urgent problem of modern medicine, which is associated with the multifactorial nature of this disease, which determines the use of a differentiated approach to the treatment of bruxism, in order to normalize the functions of the dental system and the psychoemotional state of patients.…”
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15004
Identification and Experimental Validation of Biomarkers Related to MiR-125a-5p in Chronic Obstructive Pulmonary Disease
Published 2025-03-01“…Enrichment analysis showed their roles in various cellular functions. In addition, significant associations were identified between 9 distinct cells and biomarkers. …”
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15005
Integrative analysis of signaling and metabolic pathways, immune infiltration patterns, and machine learning-based diagnostic model construction in major depressive disorder
Published 2025-04-01“…GSVA and immune infiltration results indicate that patients with MDD exhibit differences from normal individuals in various aspects, including biological processes, signaling pathways, metabolic processes, and immune cells. To investigate the functions and biological significance of differentially expressed genes in MDD patients, we performed GO and KEGG enrichment analyses on the differentially expressed genes from five databases (GSE98793, GSE32280, GSE38206, GSE39653, and GSE52790). …”
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15006
Transcriptomic and Proteomic Analyses of the Liver and Ileum Identify Key Genes and Pathways Associated with Low and High Groups of Social Genetic Effect of Residual Feed Intake
Published 2025-05-01“…They consumed less overall feed but had a higher intake per visit. Differentially expressed genes and proteins were identified in the liver and ileum and were associated with processes such as mitochondrial functions, oxidative phosphorylation, and cholesterol metabolism. …”
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15007
Impact of Intrauterine Insults on Fetal and Postnatal Cerebellar Development in Humans and Rodents
Published 2024-11-01“…Moreover, as postnatal functionality of the cerebellum is multifaceted, enveloping sensorimotor, cognitive, and emotional domains, prenatal disruptions in cerebellar development can result in a large variety of neurological and mental health disorders. …”
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15008
Rapid diagnosis of latent and active pulmonary tuberculosis by autofluorescence spectroscopy of blood plasma combined with artificial neural network algorithm
Published 2024-12-01“…By optimizing the ANN structure and activation functions, the ANN three-classification model achieves average classification accuracy of 96.3 %, and the accuracy of healthy persons, latent TB infections and active TB patients are 100 %, 83.3 % and 97.5 %, respectively, which is much better than the results of traditional Principal component analysis (PCA) and Linear discriminant analysis (LDA) method. …”
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15009
Integrative Transcriptomic and Biochemical Analysis Reveals Key HSP20/Alpha-Crystallin Genes Associated with Heat Tolerance in Rice
Published 2025-07-01“…These genes play essential roles in protein stabilization, folding, and preventing aggregation, critical functions for maintaining protein balance under stress conditions. …”
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15010
Spatiotemporal Coupling of New-Type Urbanization and Ecosystem Services in the Huaihe River Basin, China: Heterogeneity and Regulatory Strategy
Published 2025-01-01“…These research findings offer valuable decision-making support for the differentiated regulation of ecosystem functions and promotion of high-quality urbanization development in the HRB.…”
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15011
An Earlier Predictive Rollover Index Designed for Bus Rollover Detection and Prevention
Published 2018-01-01“…As vehicle rollovers annually cause a great deal of traffic-related deaths, an increasing number of vehicles are being equipped with rollover prevention systems with the aim of avoiding such accidents. To improve the functionality of active rollover prevention systems, this study provided a potential enhanced method with the intention to predict the tendency of the lateral load transfer ratio (LTR), which is the most common rollover index. …”
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15012
Cyclic surfaces accompanying non-ruled quadrics of rotation
Published 2023-09-01“…In the examples of shaping, the original rectilinear axis of a non-linear quadric of revolution and its generating line, a second-order curve, are functionally interchanged: the secondorder curve becomes the rotation axis, and the rectilinear axis becomes the generatrix. …”
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15013
Single-cell transcriptomics and tissue metabolomics uncover mechanisms underlying wooden breast disease in broilers
Published 2024-12-01“…Additionally, we found six key differential metabolites across 22 pathways. When WB occurs, myocytes and endothelial cells undergo apoptosis, macrophages are activated and exert immune functions, satellite cells participate in muscle rebuilding and repair, and the content of metabolites undergoes significant changes. …”
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15014
Two dimensional proteomic analyses revealed salinity and drought tolerance related protein alterations in two gamma-induced soybean mutants
Published 2025-05-01“…Identified proteins, which presented differential expressions under both stress conditions, were clustered under 13 distinct groups based on their cellular functions. …”
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15015
Particle track imaging simulation and expected outcomes of the Grid-based energetic neutral atom imager (GENA) for the Queqiao-2 mission
Published 2025-08-01“…In this study, a new set of response functions was developed for the instrument's collimation system design to simulate measurement outcomes. …”
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15016
Monitoring Diversity Profiles of Forested Landscapes in the Mediterranean Spain: Their Contribution to Local and Regional Vascular Plant Diversity
Published 2024-10-01“…Biodiversity monitoring is key for understanding the delivery of ecosystem functions and services. Mediterranean forests and woodlands harbor many characteristic species of the Mediterranean vascular flora, and hence, they are a good surrogate for detecting changes in biodiversity linked to global change. …”
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15017
Bioremediation potential of low-brominated polybrominated diphenyl by the phyllospheric Wickerhamomyces anomalus
Published 2025-07-01“…The aim of this research was to study the functions of overexpressing heterologous yeast genes in plants. …”
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15018
Dysregulation of autophagy during photoaging reduce oxidative stress and inflammatory damage caused by UV
Published 2025-05-01“…Central to this review is the discussion of autophagy’s protective functions, such as the clearance of damaged organelles and proteins, and its role in maintaining genomic integrity. …”
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15019
Decoding G-Quadruplexes Sequence in <i>Vitis vinifera</i>: Regulatory Region Enrichment, Drought Stress Adaptation, and Sugar–Acid Metabolism Modulation
Published 2025-04-01“…Here, we comprehensively examined the prevalence and functions of G-quadruplexes in <i>Vitis vinifera</i>. …”
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15020
Echinocandin Adaptation in <i>Candida albicans</i> Is Accompanied by Altered Chromatin Accessibility at Gene Promoters and by Cell Wall Remodeling
Published 2025-02-01“…We also find that chromatin changes are often associated with differentially expressed genes including genes with functions relevant to the ECN-adapted phenotype, such as cell wall biosynthesis. …”
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