RNA-sequencing studies suggest that microRNAs and alternative splicing of pre-mRNAs modulate immune and inflammatory responses in Holstein cattle infected with Mycobacterium avium... by Gerard Badia-Bringué, Marta Alonso-Hearn

“…Nevertheless, interest in AS is growing, driven by its recognized role in tissue-specific functions and disease mechanisms. Recent findings have revealed distinct miRNAs and AS profiles in MAP-infected cattle compared to uninfected cows, indicating that post-transcriptional regulatory mechanisms are altered during MAP infection. …”
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The Linker Histone H1.2 Is an Intermediate in the Apoptotic Response to Cytokine Deprivation in T-Effectors by Megha Garg, Lakshmi R. Perumalsamy, G. V. Shivashankar, Apurva Sarin

“…These data suggest that metabolic stressors may impinge on H1.2 dynamics favoring its activity at the mitochondrion, thereby functioning as a molecular switch for T-effector apoptosis.…”
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Studies on a direct shoot regeneration system of Citrus sinensis L. Osbeck with a high frequency in vitro by CHEN Da-ming, XU Chang-jie, ZHANG Shang-long

“…Transgenic plants appear to be a new way to citrus improvement and a powerful tool for studying gene functions. The establishment of an efficient in vitro plant regeneration system suitable for genetic transformation is the first step in this approach. …”
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URDU-CONDITIONS, TERMS, RULES AND JURISDICTIONS OF THE OMBUDSMAN IN THE LIGHT OF ISLAMIC LAW by Irfan ullah, Sajid Mahmood

“…The history of the concept and functions of accountability from Banu Abbas to Khilafat e Usmania and to Mughal dynasty has also been highlighted. …”
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The role of the vagus nerve in emotional burnout by P. I. Petrov

“…Porges considers the vagus nerve as two structurally and functionally separate branches – ventral and dorsal. …”
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Exploration of common pathogenic genes between cerebral amyloid angiopathy and insomnia based on bioinformatics and experimental validation by Xin-Yu Li, Kun Li, Yi-Han Wei, Wen-Kai Yu, Jing-Hao Wu, Kai Gao, Wen-Jun He, Peng-Peng Niu, Chan Zhang, Yu-Nan Cheng, Yu-Sheng Li

“…We explored the biological functions of these genes through immune cell infiltration, metabolic and Hallmark pathway analyses, and clinical correlation analysis. …”
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Exploring radiation resistance-related genes in pancreatic cancer and their impact on patient prognosis and treatment by Dong Dai, Dong Dai, Sen Wang, Jiaze Li, Yu Zhao

“…The obtained differentially expressed genes were enriched by GO and KEGG to reveal their biological functions. …”
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MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension. by Priyanka Nandakumar, Adrienne Tin, Megan L Grove, Jianzhong Ma, Eric Boerwinkle, Josef Coresh, Aravinda Chakravarti

“…Most of the significant miRNAs were downregulated and have critical roles in immune cell functions. Future studies are needed to replicate our findings and determine whether the downregulation of these miRNAs in immune cells may influence CKD progression or complications.…”
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Flu‐CED: A comparative transcriptomics database of influenza virus‐infected human and animal models by Yue Wu, Jue Wang, Jing Xue, Zhiguang Xiang, Jianguo Guo, Lingjun Zhan, Qiang Wei, Qi Kong

“…Using integrated and processed transcriptomic data, we established a user‐friendly website for realizing the integration, online retrieval, visualization, and exploration of gene expression of influenza virus infection in different species and the biological functions involved in differential genes. Flu‐CED can quickly query single and multi‐gene expression profiles, combining different experimental conditions for comparative transcriptome analysis, identifying differentially expressed genes (DEGs) between comparison groups, and conveniently finding DEGs. …”
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Integrated analysis of electrical stimulation effects on Pseudomonas aeruginosa PAO1 inoculated denitrifying community: targeted and untargeted metabolomic analysis of phenazine bi... by Li Wu, Li Wu, Yong Liu, Yong Liu, Jianping Deng, Jianping Deng, Shuanglin Gui, Shuanglin Gui, Hanbing Nie, Hanbing Nie

“…Untargeted metabolomic analysis demonstrated significant alterations in bacterial metabolic activity under electrical stimulation, identifying 140 differential metabolites. Among these, indole, a signaling molecule with QS-like functionality, exhibited the highest VIP score as an upregulated metabolite, and another indole derivative, brassicanal A, was also elevated. …”
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Analysis of Coupled and Coordinated Development of Cultivated Land Multifunction and Agricultural Mechanization in China by Yuan Qin, Zhongbo Li, Enwei Huang, Dale Lu, Shiming Fang, Xin Duan, Lulu Gao, Yinuo Zhao, Hanzhe Kang, Zixuan Liu, Zhen Yang

“…The CLM level in western regions was significantly lower than in eastern and central regions, with regional differences in AM development gradually expanding. (2) Driving factors of coupled and coordinated development varied significantly across regions: eastern regions were primarily driven by technological innovation, central regions were influenced by production efficiency and social security, and western regions were mainly constrained by ecological functions. (3) Natural conditions such as cultivated land area, quality, and land flatness significantly impact the coordinated development of AM and CLM. …”
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Transcriptome analysis reveals the candidate genes associated with skin color variation in Luciobarbus capito by Longwu Geng, Xinchi Shang, Haijun Wei, Guangxiang Tong, Wei Xu, Youyi Kuang

“…Among the DEGs, six genes (ywhae, c3, cdk4, mt-atp6, rhoa, and tuba1) were associated with melanin synthesis and transport, functioning through the PI3K/Akt and cAMP signaling pathways. …”
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The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism by Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi

“…After crossing the two strains together, we induced conditional cell death by doxycycline to construct a mouse model of liver fibrosis. We analyzed differentially expressed genes by RNA sequencing and explored their biological functions. …”
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The Problem of the Reliability of Bending Models for Composite Plates of Medium Thickness by Shvabyuk V. I., Rotko S. V., Ribeiro L. F., Kuts N. H., Zakharchuk V. I., Shvabyuk V. V.

“…Therefore, to provide guaranteed accuracy of the results, some researchers of these problems have introduced such a concept as “energy consistency” between the functions of representation of the displacement vector components, their number, the order of equations, and the number of boundary conditions. …”
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Specific features of cognitive skill development in athletes of situational sports by Vyacheslav Romanenko, Yrui Tropin, Leonid Podrigalo, Natalya Boychenko, Anatoly Abdula, Nataliia Sereda, Yaroslav Yatsiv

“…Situational sports, including team sports and martial arts, require athletes to demonstrate a high level of executive functions. The development of these functions follows specific patterns influenced by the nature of sports activity. …”
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Opposition-based learning techniques in metaheuristics: classification, comparison, and convergence analysis by Rihab Lakbichi, Farouq Zitouni, Saad Harous, Aridj Ferhat, Abdelhadi Limane, Abdulaziz S. Almazyad, Guojiang Xiong, Ali Wagdy Mohamed

“…The results indicate that quasi-reflection opposition-based learning consistently outperforms other OBL variants, demonstrating superior convergence speed and solution quality across most benchmark functions.…”
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Comparative EEG reveals general and conspecific vocalization sensitivities in evolutionarily distant mammal species by Boglárka Morvai, Marianna Boros, Elodie Ferrando, Lilla Magyari, Attila Andics

“…These findings reveal that general and conspecific vocalization sensitivities are served by evolutionarily conserved, temporally and functionally distinct neural mechanisms.…”
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Proteomic Analysis of <i>Listeria monocytogenes</i> Subjected to Pulsed Magnetic Field by Di Chen, Jingya Qian, Shuhao Huo, Feng Wang, Haile Ma, Shan Liu

“…The disruption of cellular functions and metabolic pathways may contribute to the death of <i>L. monocytogenes</i> under PMF treatment. …”
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Pathological mechanisms and related markers of steroid-induced osteonecrosis of the femoral head by Longyu Li, Shangkun Zhao, Zikuan Leng, Songfeng Chen, Yifang Shi, Lijun Shi, Jinfeng Li, Keya Mao, Hai Tang, Bin Meng, Yisheng Wang, Guowei Shang, Hongjian Liu

“…Additionally, the biological functions of mesenchymal stem cells (MSCs) and exosomes (Exos) in SONFH have attracted increasing attention.Conclusions The pathological mechanisms of SONFH are complex. …”
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A Neural Device Inspired by Neuronal Oscillatory Activity with Intrinsic Perception and Decision‐Making by Congtian Gu, Guoliang Ma, Mengze Zhang, Hu Shen, Liaoyuan Pu, Yanhe Song, Shilong Yan, Dakai Wang, Kaixian Ba, Bin Yu, Zhiwu Han, Luquan Ren

“…This is accomplished using a single interface, which reduces data transmission, simplifies functionality, and eliminates the need for an external power supply. …”
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