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1401
Identification, expression profiling and potential functional roles of nuclear receptors in the social aphid Pseudoregma bambucicola
Published 2025-05-01“…In insects, NRs not only govern essential physiological functions including metabolism, development, and reproduction, but also play pivotal roles in regulating caste differentiation and division of labor within social insect colonies. …”
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Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript.
Published 2010-05-01“…However, despite the widespread expression of key markers such as Oct4 and the appearance of a characteristic undifferentiated morphology, functional ES cells may represent only a small fraction of the cultures grown under self-renewing conditions. …”
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1404
Genomic Analysis of Indel and SV Reveals Functional and Adaptive Signatures in Hubei Indigenous Cattle Breeds
Published 2025-06-01“…This study investigates the distribution and functional impact of insertions and deletions in five Hubei indigenous cattle breeds. …”
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1405
Functionalized GelMA/CMCS Composite Hydrogel Incorporating Magnesium Phosphate Cement for Bone Regeneration
Published 2025-01-01“…This study aims to develop a functionalized GelMA/CMCS composite hydrogel incorporating magnesium phosphate cement (MPC) for enhanced bone regeneration. …”
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1406
Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions
Published 2025-05-01“…Summary: Adequate sleep (AS) is vital for physiological functions, yet a third of US adults sleep less than recommended. …”
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The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A
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1409
Multiple strategies association revealed functional candidate FASN gene for fatty acid composition in cattle
Published 2025-02-01“…We investigated potential functional candidate genes for FA in beef cattle by integrating genomic and transcriptomic dataset through multiple strategies. …”
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1410
Osteogenic and Antibacterial Response of Levofloxacin-Loaded Mesoporous Nanoparticles Functionalized with <i>N</i>-Acetylcysteine
Published 2025-04-01“…<b>Methods</b>: MBGN of composition 82.5 SiO<sub>2</sub>—17.5 CaO have been synthesized, loaded with levofloxacin, and functionalized with NAC (MBGN-L-NAC). The antimicrobial activity against mature <i>S. aureus</i> biofilms and bioactivity of the nanosystem have been evaluated, as well as its biocompatibility and ability to promote murine pre-osteoblastic MC3T3-E1 differentiation. …”
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1411
Dietary Branched‐Chain Amino Acids Modify Postinfarct Cardiac Remodeling and Function in the Murine Heart
Published 2025-02-01“…The low BCAA diet preserved stroke volume and cardiac output after MI, whereas the high BCAA diet promoted progressive decreases in cardiac function. Although BCAAs were required for myofibroblast differentiation in vitro, cardiac fibrosis, scar collagen topography, and cardiomyocyte cross‐sectional area were not different between the dietary groups; however, male mice fed the high BCAA diet had longer cardiomyocytes and higher capillary density compared with the low BCAA group. …”
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1412
Postoperative evaluation of visual and cognitive functions following cataract surgery in patients with age-related cataracts: a prospective longitudinal study
Published 2025-01-01“…IntroductionCataracts are associated with a decline in both cognitive and visual functions. This study examines postoperative changes in cognitive and visual functions in patients with age-related cataracts, focusing on the differential effects of unilateral and bilateral cataract surgeries on these functions. …”
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Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response.
Published 2015-01-01“…The coxsackie- and adenovirus receptor (CXADR) is a member of the immunoglobulin protein superfamily, present in various epithelial cells including glomerular epithelial cells. Beside its known function as a virus receptor, it also constitutes an integral part of cell-junctions. …”
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Altered Disrupted-in-Schizophrenia-1 Function Affects the Development of Cortical Parvalbumin Interneurons by an Indirect Mechanism.
Published 2016-01-01“…Here, the effects of two loss-of-function point mutations in the mouse Disc1 sequence (Q31L and L100P) on cortical inhibitory interneurons were investigated. …”
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Aquaporin Channels in Skin Physiology and Aging Pathophysiology: Investigating Their Role in Skin Function and the Hallmarks of Aging
Published 2024-10-01“…AQPs, primarily known for facilitating water transport, are significant for normal skin functions, including hydration and the movement of molecules like glycerol and hydrogen peroxide, which influence various cellular processes and functions. …”
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Human stem cell-derived neurons: a system to study human tau function and dysfunction.
Published 2010-11-01“…We found that the shortest 3 repeat tau isoform, similarly to human brain, is the first to be expressed during neuronal differentiation while the other 5 tau isoforms are expressed later. …”
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MODULATION OF FUNCTIONAL MACROPHAGE ACTIVITY BY HLDF6 PEPTIDE UPON ADDING OPIATE RECEPTOR AGONISTS
Published 2014-07-01“…Abstract.The effect of a hexamer fragment of the peptide differentiation factor of the HL–60 cell line, HLDF6, on functional activity of C57Bl/6 mouse macrophages upon adding selective agonists of μ–, δ– and κ–type opiate receptors (DAGO, DADLE and Dynorphin (1–13) has been studied in the cell culture. …”
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Effects of Human Umbilical Cord Mesenchymal Stem Cells on Human Trophoblast Cell Functions In Vitro
Published 2016-01-01“…Few treatments exist, however, that target improving trophoblast cell function. Human umbilical cord mesenchymal stem cells (hUCMSCs) are capable of self-renewing, can undergo multilineage differentiation, and have homing abilities; in addition, they have immunomodulatory effects and paracrine properties and thus are a prospective source for cell therapy. …”
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Hermetia illucens Protein Conjugated with Glucose via Maillard Reaction: Antioxidant and Techno-Functional Properties
Published 2021-01-01“…The food industry is considering novel sources of proteins with enhanced functionalities to meet the increasing demand and population growth. …”
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