Can patient self-evaluation of functional status be used for evaluation of impairment of motor function in Guillain-Barré syndrome? Mapping clinician- and patient-reported outcomes... by Antoine Regnault, Angély Loubert, Stéphane Quéré, Qun Lin, Glen Frick, Hirokazu Ishida, Yuko Abeta, Helene Chevrou-Severac

“…Evaluation of the R-ODS threshold that could approximate the functional motor symptom categories based on HFGS (score of 0 or 1) revealed a range of values from 60 to 80. …”
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Correction: Nakkala et al. Differential Regulation of DC Function, Adaptive Immunity, and MyD88 Dependence by Two Squalene Emulsion-Based Vaccine Adjuvants.... by Jayachandra Reddy Nakkala, Yibo Li, Labone Akter, Xinliang Kang, Xinyuan Chen

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The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster. by Shuwa Xu, Nathaniel Hafer, Blessing Agunwamba, Paul Schedl

“…Here we show that orb2 is also expressed in the adult male germline and that it has essential functions in programming the progression of spermatogenesis from meiosis through differentiation. …”
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Fear perception as a function of hemisphere- and time-specific dynamics in the medial temporal lobes by Enya M. Weidner, Lea Marie Reisch, Malena Mielke, Christian G. Bien, Johanna Kissler

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Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. by Qingsong Li, Shan Bian, Janet Hong, Yoko Kawase-Koga, Edwin Zhu, Yongri Zheng, Lizhuang Yang, Tao Sun

“…The adult hippocampus consists of the dentate gyrus (DG) and the CA1, CA2 and CA3 regions and is essential for learning and memory functions. During embryonic development, hippocampal neurons are derived from hippocampal neuroepithelial cells and dentate granular progenitors. …”
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Physiological criteria of functional fitness and determinants of physical work capacity of highly skilled wrestlers by Oleksandr Pryimakov, Sergii Iermakov, Jerzy Eider, Stanislav Prysiazhniuk, Natalija Mazurok

“…The objective of the work is to study the key factors of highly skilled wrestler fitness structure determining the level of their functional state and physical work capacity at the stage of maximum realization of individual capacities. …”
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Functional disorders of the gastrointestinal tract in children of different age groups (a literature review) by S. M. Nedelska, I. V. Samokhin, O. V. Kriazhev, D. O. Yartseva, T. H. Bessikalo, L. I. Kliatska

“…This requires a physician at various levels of medical care to provide timely diagnosis, differential diagnosis between organic gastrointestinal diseases, and timely correction of functional disorders.…”
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STRUCTURAL AND FUNCTIONAL ENAMEL RESISTANCE (TER-TEST) IN CHILDREN WHO ARE STUDYING IN BOARDING SCHOOL by О. Narepekha, Т. Lisak

“…To estimate the structural and functional resistance of enamel in children of boarding schools. …”
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Single-Cell Landscape and a Macrophage Subset Enhancing Brown Adipocyte Function in Diabetes by Junfei Gu, Jiajia Jin, Xiaoyu Ren, Xinjie Zhang, Jiaxuan Li, Xiaowei Wang, Shucui Zhang, Xianlun Yin, Qunye Zhang, Zhe Wang

“…A novel Rarres2+macrophage subset promoted the differentiation and metabolic function of brown adipocytes via adipose-immune crosstalk. …”
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LINC00673 binds with leptin to regulate osteogenic function in periodontal ligament stem cells by Yang Yang, Peng Yang, Yuxing Zhang, Zhaoyan Wu, Xuxia Wang, Jun Zhang

“…Results As predicted, miR-188-3p interacts with LINC00673 directly, and miR-188-3p overexpression increases osteogenic differentiation. However, overexpression of LINC00673 reversed this effect, suggesting that LINC00673 functions as a competing endogenous RNA for miR-188-3p. …”
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Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos. by Kathryn S McClelland, Elanor N Wainwright, Josephine Bowles, Peter Koopman

“…We also generated a novel double knockdown of Gli1 and Gli2, revealing defects in Leydig cell differentiation in the fetal testis. Finally, we gained insight into the roles of Adamts19 and Ctrb1, genes of unknown function in sex determination and gonadal development. …”
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Modulation of intracellular kinase signaling to improve TIL stemness and function for adoptive cell therapy by Hao Feng, Ling Qiu, Zixiao Shi, Yao Sheng, Peipei Zhao, Di Zhou, Fei Li, Hailin Yu, Yanan You, Hui Wang, Ming Li, Shurong Zhu, Yan Du, Jun Cui, Jingwei Sun, Yarong Liu, Hua Jiang, Xin Wu

“…This calls for a robust expansion process to produce a large number of cells for clinical usage while at the same time maintaining favorable anti‐tumor function and memory phenotype. Previous studies showed that the PI3K‐AKT signaling pathway plays a key role in the regulation of T cell activation, differentiation and memory formation. …”
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Transcriptional and Genomic Targets of Neural Stem Cells for Functional Recovery after Hemorrhagic Stroke by Le Zhang, Wenjing Tao, Hua Feng, Yujie Chen

“…However, due to the complexity of NSCs and their microenvironment, current strategies cannot satisfactorily enhance functional recovery after hemorrhagic stroke. It is well known that transcriptional and genomic pathways play important roles in ensuring the normal functions of NSCs, including proliferation, migration, differentiation, and neural reconnection. …”
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Biological Functionalities of Transglutaminase 2 and the Possibility of Its Compensation by Other Members of the Transglutaminase Family by Benedict Onyekachi Odii, Peter Coussons

“…It is a unique member of the transglutaminase family owing to its specialized biochemical, structural and functional elements, ubiquitous tissue distribution and subcellular localization, and substrate specificity. …”
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Transcriptional landscape of small non-coding RNAs reveals diversity of categories and functions in molluscs by Songqian Huang, Kazutoshi Yoshitake, Shigeharu Kinoshita, Shuichi Asakawa

“…To unravel the small RNA (sRNA) expression patterns and genomic function in molluscs, we generated a comprehensive sRNA dataset by sRNA sequencing (sRNA-seq) of eight mollusc species. …”
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Unlocking the life code: a review of SnoRNA functional diversity and disease relevance by Yinghui Li, Xinzhe Chen, Shudan Xiao, Haoxuan Wang, Bo Li, MeiHua Zhang, Kun Wang

“…They are widely involved in post-transcriptional modifications of ribosomal RNAs, including methylation and pseudouridylation, precisely regulating the process of ribosome biogenesis, ensuring the integrity of ribosome structure and function, and thereby guaranteeing the accuracy and efficiency of protein synthesis. snoRNAs not only maintain cell growth, proliferation, and differentiation under normal physiological conditions but also have abnormal expression closely associated with various diseases, such as cancer, cardiovascular diseases and neurodegenerative diseases. …”
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Induction of Functional Hair-Cell-Like Cells from Mouse Cochlear Multipotent Cells by Quanwen Liu, Yi Shen, Jiarong Chen, Jie Ding, Zihua Tang, Cui Zhang, Jianling Chen, Liang Li, Ping Chen, Jinfu Wang

“…The results suggested that the hair-cell-like cells derived from inner ear multipotent cells were functional following differentiation in an enabling environment.…”
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The characteristics and functional significance of disulfidptosis-related genes in head and neck squamous cell carcinoma by Haiqian Zhu, Chifeng Zhao, Haoran Zhu, Xuhui Xu, Conglin Hu, Zhenxing Zhang

“…Nevertheless, the characteristics and functional significance of disulfidptosis-related genes in head and neck squamous cell carcinoma (HNSCC) are still largely unknown. …”
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Type I collagen secreted in white matter lesions inhibits remyelination and functional recovery by Reiji Yamazaki, Morio Azuma, Yasuyuki Osanai, Tom Kouki, Takeshi Inagaki, Akiyoshi Kakita, Masaki Takao, Nobuhiko Ohno

“…In the current study, we demonstrated that collagen fibres accumulated in the demyelinated lesions of multiple sclerosis patients (age range 23–80 years) and white matter lesions of stroke patients (age range 80–87 years), suggesting that the accumulation of collagen fibres correlates with remyelination failure in these lesions. To investigate the function of collagen fibres in the white matter lesions, we generated two types of white matter injury in mice. …”
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Multi-function of adipose-derived stem cells on gut disorder: from bench to bedside by Jiatong Zhao, Shuzi Xin, Xiaohui Liu, Weikai Shi, Boya Wang, Hongli Wang, Yi Wang, Rongxuan Hua, Yize Li, Lei Gao, Xin Lu, Jingdong Xu

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