Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity by Leonore Raudszus, Farbod Bahreini, Susanne Allan, Kai-Uwe Kalies, Charles C. Caldwell, Kathrin Kalies

“…However, recent evidence highlights a phenotypic and functional heterogeneity of neutrophils that extends well beyond their traditional - potentially harmful- role as first responders. …”
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Dicer deficiency affects microglial function during demyelination and impairs remyelination by Ajai Tripathi, Nagendra Kumar Rai, Aaron Perles, Haley Courtney, Claire Jones, Adya Sapra, Jason Plemel, Ranjan Dutta

“…Here, we investigate the role of Dicer1, a critical enzyme in microRNA biogenesis, in affecting microglial function, demyelination, and remyelination. Loss of Dicer1 in microglia resulted in amplified inflammatory responses, defective myelin debris clearance, and disruption of metabolic homeostasis, leading to exacerbated demyelination and delayed remyelination. …”
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The regulatory role of placental extracellular vesicle on trophoblast and endothelial cell functions by Kunfeng Bai, Kunfeng Bai, Xintong Li, Yanjie Guo, Ye Shang, Leqian Lin, Philip C. N. Chiu, Philip C. N. Chiu, Cheuk-Lun Lee

“…This study aims to isolate placental EVs (pEVs) from placental explant to examine their regulatory roles on EVT and endothelial cell functions. pEVs were successfully isolated from ex vivo cultured placental explant, which were capable to be internalized by EVTs and endothelial cells. pEVs stimulated the differentiation of trophoblast stem cells (TSCs) and enhanced the migration and invasion abilities of EVTs via CD147 receptor. …”
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The Functions and Mechanisms of the Cohesin Complex in Regulating the Fate Determinations of Stem Cells by Jianghong Xiang, Yihan Lai, Zuping He

“…Variants in the subunit components of the cohesin complex and proteins’ modifications further confer functional plasticity, and its mutations can lead to abnormal stem cell functions and are correlated with diseases including cancers. …”
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Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets by Reham Hassan Mekky, Mohammed E. Abo‐El Fetoh, Safaa A. Faheem, Abdullah F. Radwan, Mariam H. Fawzy, Aya M. Mustafa, Mohamed A. Said, Daniela Calina, Javad Sharifi‐Rad, William C. Cho

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Phenotypic, Functional, and Safety Control at Preimplantation Phase of MSC-Based Therapy by Wioletta Lech, Anna Figiel-Dabrowska, Anna Sarnowska, Katarzyna Drela, Patrycja Obtulowicz, Bartlomiej Henryk Noszczyk, Leonora Buzanska, Krystyna Domanska-Janik

“…Thus, in this paper we highlight the urgent necessity to develop the more sensitive and selective methods for prediction and control cells fate and functioning during the time of growth in vitro.…”
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THE FUNCTIONAL EFFECTIVENESS OF A CELL-ENGINEERED CONSTRUCT FOR THE REGENERATION OF ARTICULAR CARTILAGE by V. I. Sevastianov, G. A. Dukhina, A. M. Grigoriev, N. V. Perova, L. A. Kirsanova, N. N. Skaletskiy, D. G. Akhaladze, S. V. Gautier

“…The aim of this study is an analysis of the functional effectiveness of a biomedical cell product consisting of a biopolymer microheterogeneous collagen-containing hydrogel (BMCH), human adipose-derived mesenchymal stromal cells (hADMSCs), and chondrogenic induction medium in the regeneration of articular cartilage. …”
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Functional Characteristics of Multipotent Mesenchymal Stromal Cells from Pituitary Adenomas by Kaspars Megnis, Ilona Mandrika, Ramona Petrovska, Janis Stukens, Vita Rovite, Inga Balcere, Laima Sabine Jansone, Raitis Peculis, Valdis Pirags, Janis Klovins

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The The impact of vitamin D on muscle function and bone health in postmenopausal women by Katarzyna Agopsowicz, Katarzyna Blicharz, Anna Bieniasz, Michalina Piwowar, Anna Zdziebło, Martyna Biernacka, Dominika Stolarczyk, Katarzyna Zdziebło, Piotr Mojżesz, Igor Biernacki

“…Recent studies have identified vitamin D receptors (VDR) in human muscle tissue, supporting the hypothesis that vitamin D contributes to muscle cell proliferation, differentiation, and function (Iolascon G et al. 2018). …”
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Radiation decreases bronchial epithelial progenitor function as assessed by organoid formation by Merian E. Kuipers, Dennis K. Ninaber, Krista C.J. van Doorn-Wink, Annelies M. Slats, Pieter S. Hiemstra

“…Since these effects are incompletely understood, the aim of the present study was to evaluate the effect of ionizing radiation (IR) on cultured well-differentiated primary bronchial epithelial cells (PBEC) with a focus on cytotoxicity, barrier formation, inflammation and epithelial progenitor function. …”
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Experimental study of Rac1 regulating osteoclast function in hypoxic environment by GU Jiahong, TIAN Yuanye, KANG Feiwu

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The dimethyloxalylglycine-functionalized nanofibers for in situ regeneration of infected developing dental roots by Yeon Jee Yoo, Eun-Hye Lee, Jieun Bae, Woo Jin Kim, Chan Ho Park, Shin Hye Chung, Won Jun Shon, WooCheol Lee, Kyung Mi Woo

“…This study explores the potential of poly(ε-caprolactone) fibers (PCLF) functionalized with a hypoxia-inducible factor 1-alpha (HIF-1α) stabilizing small molecule dimethyloxalylglycine (DMOG) for in situ regeneration in the context of dental root repair in developing immature teeth. …”
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Exploring the Functionality of the Krüppel-like Factors in Kidney Development, Metabolism, and Diseases by Itzel S. Salmon-Cabrales, David A. de la Garza-Kalife, Gabriel García-González, Ana E. Estrada-Rodríguez, Marco Antonio Jiménez-Gutiérrez, Michelle G. Santoyo-Suárez, Oscar Rodríguez-Núñez, Elsa N. Garza-Treviño, Diego F. Benítez-Chao, Gerardo R. Padilla-Rivas, Jose Francisco Islas

“…This process involves various biological mechanisms, in which the Krüppel-like factors (KLFs), a family of transcription factors, are essential for regulating development, differentiation, proliferation, and cellular apoptosis. …”
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Extracellular Matrix Signaling Cues: Biological Functions, Diseases, and Therapeutic Targets by Tian Zhao, Ye Huang, Jingfei Zhu, Yujie Qin, Hao Wu, Jiaxuan Yu, Qianwen Zhai, Shun Li, Xiang Qin, Dengfeng Wang, Tingting Li, Yiyao Liu

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Solvability of Infinite Systems of Third Order Differential Equations in a Sequence Space $n ( \phi)$ via Measures of Non-Compactness by Santosh Kumar, Pendo Malaki, Mohammad Mursaleen

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Second Order Equations in Functional Spaces: Qualitative and Discrete Well-Posedness by A. Ashyralyev, J. Pastor, S. Piskarev, H. A. Yurtsever

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Certain Families of Analytic Functions Characterized by p,q-Difference Operator by Rashid Murtaza, null Adnan, Amna Aziz, Abdulaziz H. Alghtani, Ilyas Khan, Mulugeta Andualem

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Certain Properties of Extended Mittag-Leffler-Type Function of Arbitrary Order by Maged Bin-Saad, Jihad Younis

“…Furthermore, we establish fractional integral and differential perators associated with this extended Mittag-Leffler type function. …”
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A study of generalized Mittag-Leffler-type function of arbitrary order by Bin-Saad Maged, Younis Jihad

“…Further, for this generalized Mittag-Leffler-type function of arbitrary order, we create fractional integral and differential operators. …”
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Constructions of the Soluble Potentials for the Nonrelativistic Quantum System by Means of the Heun Functions by Shishan Dong, G. Yáñez-Navarro, M. A. Mercado Sanchez, C. Mejía-García, Guo-Hua Sun, Shi-Hai Dong

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