Adipose Mesenchymal Stem Cell-Derived Exosomes Enhance PC12 Cell Function through the Activation of the PI3K/AKT Pathway by Yong Xie, Yangping Chen, Yuyuan Zhu, Xia Chen, Tiecheng Lin, Dan Zhou

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Comprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination. by Xiaomin Dong, Kenian Chen, Raquel Cuevas-Diaz Duran, Yanan You, Steven A Sloan, Ye Zhang, Shan Zong, Qilin Cao, Ben A Barres, Jia Qian Wu

“…In the present study, we performed ab initio transcriptome reconstruction using eight purified cell populations from mouse cortex and detected more than 5000 lncRNAs. Predicting the functions of lncRNAs using cell-type specific data revealed their potential functional roles in Central Nervous System (CNS) development. …”
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GDF11 restores the impaired function of EPCs-MA by promoting autophagy: GDF11 ameliorates endothelial progenitor cell aging by promoting autophagy by Liu Donghua, Zhang Yang, Liu Xin, Huang Qihe, Zhang Xiaofang, Yang Rui, Zhao Yue, Li Penghui, He Jiayi, Zhang Kexiao, Pan Zhenwei, Liu Huiwen, Yang Baofeng

“…Our study aimed to assess the effects of Growth and differentiation factor 11 (GDF11) on the function of endothelial progenitor cells in middle-age individuals (EPCs-MA) isolated from mouse bone marrow and to explore the mechanistic relationship between GDF11 and age-related ALP impairment.…”
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A Refined Fuzzy MARCOS Approach with Quasi-D-Overlap Functions for Intuitive, Consistent, and Flexible Sensor Selection in IoT-Based Healthcare Systems by Mahmut Baydaş, Safiye Turgay, Mert Kadem Ömeroğlu, Abdulkadir Aydin, Gıyasettin Baydaş, Željko Stević, Enes Emre Başar, Murat İnci, Mehmet Selçuk

“…To overcome these limitations, this study proposes a novel fuzzy decision-making framework by integrating Quasi-D-Overlap functions into the fuzzy MARCOS (Measurement of Alternatives and Ranking According to Compromise Solution) method. …”
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SLC26A4 C.317C > A Variant: Functional Analysis and Patient‐Derived Induced Pluripotent Stem Line Development by Yijing Li, Tao Sun, Sang Hu, Hongen Xu, Teng Zhang, Jinlong Liu, Shuangshuang Lu, Bing Wang, Guo Dan

“…Although missense variants are relatively common, their specific effects on protein function remain unclear. Consequently, there is an urgent need to establish an in vitro system to investigate how these variants impact SLC26A4 protein function. …”
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Next-Generation Biomaterials for Wound Healing: Development and Evaluation of Collagen Scaffolds Functionalized with a Heparan Sulfate Mimic and Fibroblast Growth Factor 2 by Merel Gansevoort, Sabine Wentholt, Gaia Li Vecchi, Marjolein de Vries, Elly M. M. Versteeg, Bouke K. H. L. Boekema, Agnes Choppin, Denis Barritault, Franck Chiappini, Toin H. van Kuppevelt, Willeke F. Daamen

“…We present a novel approach where porous type I collagen scaffolds were covalently functionalized with ReGeneRating Agent (RGTA^®) OTR4120. …”
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Itaconate derivative 4-OI inhibits M1 macrophage polarization and restores its impaired function in immune thrombocytopenia through metabolic reprogramming by Qiang Liu, Anli Liu, Shaoqiu Leng, Xiaoyu Zhang, Xiaolin Wang, Zhang Cheng, Shuwen Wang, Jun Peng, Qi Feng, Sihan Zhou, Xiuyuan Hao

“…Macrophage polarization, antigen-presenting functions, and phagocytic capability were measured via flow cytometry and enzyme-linked immunosorbent assay (ELISA). …”
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Pantoprazole (PPZ) Inhibits RANKL-Induced Osteoclast Formation and Function In Vitro and Prevents Lipopolysaccharide- (LPS-) Induced Inflammatory Calvarial Bone Loss In Vivo by Yu-Xi Li, Fu-Chao Chen, Ting Liu, Zhao-Peng Cai, Keng Chen, Guo-Xue Tang, Jun-Shen Huang, Xiang-Ge Liu, Jia-Jun Huang, Peng Wang, Yu-Wei Liang, Lin Huang

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Bias-Corrected Fixed Item Parameter Calibration, with an Application to PISA Data by Alexander Robitzsch

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Alternative splicing fine-tunes prey shift of Coccinellini lady beetles to non-target insect by Xuefei Tang, Xinhui Xia, Yuqi Liu, Xiyao Hong, Yuhao Huang, Guannan Li, Yuansen Liang, Xueqing Wang, Hong Pang, Yuchen Yang

“…Compared to aphid-feeding, all three lady beetles were subject to substantial splicing changes when preying on mealybugs. Most of these differentially spliced genes (DSGs) were not differentially expressed, and regulated different pathways from differentially expressed genes, indicating the functionally nonredundant role of AS. …”
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Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling by Katherine A. Kentistou, Brandon E. M. Lim, Lena R. Kaisinger, Valgerdur Steinthorsdottir, Luke N. Sharp, Kashyap A. Patel, Vinicius Tragante, Gareth Hawkes, Eugene J. Gardner, Thorhildur Olafsdottir, Andrew R. Wood, Yajie Zhao, Gudmar Thorleifsson, Felix R. Day, Susan E. Ozanne, Andrew T. Hattersley, Stephen O’Rahilly, Kari Stefansson, Ken K. Ong, Robin N. Beaumont, John R. B. Perry, Rachel M. Freathy

“…We highlight the dual role of PPARG (fetal-acting) in adipocyte differentiation and placental angiogenesis. NOS3 (fetal and maternal-acting), NRK (fetal), and ADAMTS8 (maternal-acting) have been implicated in placental function and hypertension. …”
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Monomiality Principle and Eigenfunctions of Differential Operators by Isabel Cação, Paolo E. Ricci

“…We apply the so-called monomiality principle in order to construct eigenfunctions for a wide set of ordinary differential operators, relevant to special functions and polynomials, including Bessel functions and generalized Gould-Hopper polynomials.…”
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Enlarged multicystic ovaries in an infertile woman: Thinking beyond controlled ovarian stimulation by Aishwarya Kapur, G. S. Triveni, Anu Aggarwal, Manju Puri

“…Functional gonadotroph adenoma (FGA) is a rare, slow-growing pituitary tumour which presents in the reproductive age group with abnormal uterine bleeding (AUB), infertility and ovarian hyperstimulation syndrome. …”
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Stability Analysis of Retarded Differential Inclusions by Jiafu Wang, Gui Zhang

“…The purpose of this paper is to establish a result on the stability and asymptotical stability for retarded differential inclusions. Comparing with the previous results, the main result obtained in this paper allows Lyapunov functions to be nonsmooth. …”
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Constipation in Children: Assisting Paediatricians by I. N. Zakharova, N. G Sugyan, I. D. Maykova, I. V. Berezhnaya, I. М. Kolobashkina

“…Only 1.6% of all cases occur due to organic disorders, while the rest are purely functional. The article describes risk factors for juvenile constipation and an algorithm for differential diagnosis of chronic constipation and Hirschprung’s disease. …”
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Comparative analysis of navy bean starch nanoparticles prepared via ultrasound, enzymatic debranching, and their synergistic application by Nora Ali Hassan, Aijun Hu, Ammar B. Altemimi, Jie Zheng, Ran Han, Darya Khan, Mohammad Ali Hesarinejad, Tarek Gamal Abedelmaksoud

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BcACS6 overexpression promotes the accumulation of L-cysteine and L-tyrosine and improves the quality of Wucai by Wenying Zhang, Guoliang Li, Mengnan Xiong, Qiuhong Chen, Xun Gao, Kangkang Wang, Zhengyan Zhao, Lixue Zhou, Youzhi Liu, Jinfeng Hou, Wenjie Wang, Jianqiang Wu, Guohu Chen, Xiaoyan Tang, Lingyun Yuan, Chenggang Wang

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Morpho‐Physiological Traits and Dehydration Tolerance of High‐Altitude Andean Wetland Vegetation in the Chilean Atacama Region by Dariel López, Patricia L. Sáez, Lohengrin A. Cavieres, Fernanda C. Beveridge, Felipe Saavedra‐Mella, León A. Bravo

“…In this study, we characterized the functional trait spectrum of dominant plant species within the Salar de Pedernales, Quebrada Leoncito (Leoncito) and Río Negro HAWAs and explored the relationships between these traits and key environmental variables. …”
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Composition-Differentiation Operator on the Bergman Space by K. O. Aloo, J. O. Bonyo, I. Okello

“…We investigate the properties of composition-differentiation operator Dψ on the Bergman space of the unit disk L2a(D). …”
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Spatial phenotyping of human bronchial airways in obstructive lung disease by Latifa Khalfaoui, Raymond M. Moore, Jose. C. Villasboas, Kaitlyn R. Whitaker, Brenna C. Novotny, Michael A. Thompson, Christina M. Pabelick, Y. S. Prakash

“…Abstract Chronic respiratory diseases such as asthma and COPD involve interactions between multiple resident and immune cell types within bronchial airways, resulting in structural and functional changes. Thus cellular heterogeneity, arrangements and associated neighborhoods as well as interactions between cells and matrices represent intriguing yet challenging areas of study. …”
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