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19921
Epigenetic Mechanisms Affecting the Development of Atherosclerosis: A Narrative Review
Published 2025-03-01“…Macrophages and monocytes, when exposed to inflammatory stimuli, undergo alterations in their genetic and epigenetic profiles, thereby contributing to atherosclerosis progression. Our in silico analysis identified HDAC1, HDAC9, HDAC3, SIRT1, and HDAC6 as key hub genes within a protein-protein interaction network of atherosclerosis-related genes.Conclusion: Understanding epigenetic regulation can provide insights into gene activation related to functions such as inflammation, lipid metabolism, and vascular remodeling, thus influencing atherosclerosis progression. …”
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19922
Urban mobility under armed conflict: shifts in mode preferences and public transport fare behaviors
Published 2025-03-01“…Kharkiv City, the second-largest Ukrainian city, is considered, where residents continue to utilize public transport to fulfill critical daily functions, including commuting to workplaces and procuring essential goods. …”
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19923
Cardiovascular and respiratory response to ascent of the Damavand summit by classic method in elite climbers
Published 2023-07-01“…BP, HR and lung volumes were measured in basic (2000 M), BC (3100 m) the first day, C1 (3650 m) the first day, BC (3100 m) the second day after the one-night stopover, C1 (3650 m) the second day, C2 (4100 m) the second day, C2 (4100 M) third day after the one-night stopover, C3 (5000 m) and, peak (5671 m). Data were compared by repeated measures test at the significant level of P≤0.05 and Bonferroni post hoc test.Results: The results of repeated measures analysis were significant for HR, systolic BP, diastolic BP and MVV (P<0.05), but not significant for FVC and FEV1 (P≥0.05). …”
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19924
Associations between parental bonding and health-related quality of life in a clinical sample of youths aged 14–35 years in Singapore
Published 2024-10-01“…Conclusion: Our results suggest that youths who experienced quality care from their mothers exhibit better mental health functioning despite their clinical diagnoses, which suggests that early maternal care exerts an overall long-term protective effect. …”
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19925
Prevalence and predictors of postpartum depression among women attending clinics in Gaborone
Published 2025-07-01“…Background: Untreated postpartum depression (PPD) has the potential to cause significant distress or impairment in functioning with a consequent negative impact on a developing child. …”
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19926
Calculation of the Roadside Clear Zone Width along Highways Based on the Safe Slope
Published 2021-01-01“…Aiming at straight and curved sections, discriminant functions of vehicle rollover and nonrollover are fitted through Bayesian discriminant analysis, and safe slope calculation models for trucks and cars are then constructed. …”
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19927
NexoNet: Blockchain Online Social Media with User-Centric Multiple Incentive Mechanism and PoAP Consensus Mechanism
Published 2024-10-01“…Blockchain online social media (BOSM) seeks to mitigate the drawbacks of traditional centralized OSM by leveraging the decentralized nature of blockchain technology, migrating the functionalities of social media into a decentralized realm, and positioning the users at the core of the OSM ecosystem. …”
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19928
Boosting feature selection efficiency with IMVO: Integrating MVO and mutation-based local search algorithms
Published 2025-06-01“…Feature selection is crucial in machine learning and data mining, significantly impacting model performance and efficiency by reducing dimensionality, mitigating overfitting, and improving interpretability. …”
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19929
Modeling the challenges affecting the internationalization of the Persian Gulf Pro League
Published 2021-11-01“…Materials and Methods: We conducted twenty in-depth interviews with expertise involved in the functioning of the PGPL who were recruited using a convenience sampling method. …”
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19930
EVALUATING THE EFFICACY OF DISCORD-BASED BLENDED LEARNING ON ENGLISH SPEAKING SKILLS AND STUDENT ENGAGEMENT
Published 2024-12-01“…Using a qualitative case study method, the research involves 23 purposively sampled students representing diverse levels of English proficiency. Data is gathered through classroom observations, teacher interviews, and document analysis. …”
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19931
Factors Related to Fatigue among Chronic Kidney Disease Patients on Hemodialysis
Published 2025-04-01“…A total of 164 patients were recruited using convenience sampling, with sample size determined through power analysis. Data were collected using the FACIT-Fatigue Scale, a health literacy questionnaire, and an observation sheet for hemoglobin (Hb), blood pressure, and interdialytic weight gain (IDWG). …”
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19932
Evolución de los planes de estudio de Educación Física y Ciencias de la Actividad Física en la Universidad de León: estudio de un (fra)caso (Evolution of the syllabi in physical ed...
Published 2014-07-01“…Although this is a case study is presented as an example of the transformation of these studies in Spain in the last 25 years. The data analysis can infer on that at this time these studies have undergone a fundamental transformation in the heat of the hegemonic knowledge: the humanistic, social and pedagogical education, has been replaced by maters subject sport competitions the humanistic, social and pedagogical education has been replaced by sports. …”
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19933
Improving the Quality of Reshaped EoL Components by Means of Accurate Metamodels and Evolutionary Algorithms
Published 2024-11-01“…Numerical results were collected in terms of overall strain severity and residual height of the residual marks from the deep-drawn feature at the end of the reshaping step. Data were then fitted by accurate Response Surfaces trained by means of interpolant Radial Basis Functions and anisotropic Kriging algorithms, subsequently used to carry out a virtual optimization managed by multi-objective evolutionary algorithms (MOGA-II and NSGA-II). …”
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19934
A community-engaged model for promoting youth behavioral health equity: voices from Washington State’s Community Prevention and Wellness Initiative
Published 2025-08-01“…Coalition context included knowledge about the community’s demographics and dynamics, community capacity and past coalition functioning, and history. Facilitators of health equity promotion were rooted in relationships and adapting processes to enable community engagement. …”
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19935
Hydrological and morphological features and geoecological condition of the territories of the plains area of the Kuma River valley and their significance in the system of civilizat...
Published 2022-12-01“…The modern meandering belt together with the fields of the older such features create special environment forming conditions for the functioning of the stabilising components of the landscape, floodplain forest being a basic integral factor in the preservation of regional biodiversity. …”
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19936
Prospective association between social engagement and cognitive impairment among middle-aged and older adults: evidence from the China Health and Retirement Longitudinal Study
Published 2020-11-01“…The cognitive functions were tested at baseline, and 2-year and 4-year follow-up visits. …”
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19937
Multi-Frequency Information Flows between Global Commodities and Uncertainties: Evidence from COVID-19 Pandemic
Published 2022-01-01“…Consequently, we utilise the complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) and the Rényi effective transfer entropy techniques to establish the dynamic flow of information. The intrinsic mode functions (IMFs) from the CEEMDAN are carefully extracted into multi-frequencies through cluster analysis to reconstruct the series into high, medium, and low frequencies in addition to the residue. …”
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19938
Genome-wide association study of seed coat color in sesame (Sesamum indicum L.).
Published 2021-01-01“…Sesame seed coat color is related to biochemical functions involved in protein and oil metabolism, and antioxidant content. …”
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19939
An Advanced Generative AI-Based Anomaly Detection in IEC61850-Based Communication Messages in Smart Grids
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19940
Class I PI3K regulatory subunits control differentiation of dendritic cell subsets and regulate Flt3L mediated signal transduction
Published 2022-07-01“…Even though pioneering studies have established indispensable roles for specific catalytic subunits (p110δ and p110γ) in immune cells, functions of the regulatory subunits, particularly of Class I PI3K, within the hematopoietic system remain incompletely understood. …”
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