Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement by Xiao-Yi Xiong, Xiao-Yi Xiong, Xiao-Yi Xiong, Haicheng Yuan, Ying Mu, Yi He, Fang Xie, Xiao-Shuang Feng, Jia-Xin Xie, Xin-Ru Pan, Yu-Fei Wang, Jian Gong, Xiaoming Zheng, Peng-Fei Wang

“…Both MG and Mo/MΦ experience modification of immune responses after microglial repopulation, with more prominent changes in MG. Gene Ontology (GO) analysis showed that one term directly related to the “immune response” was shared between upregulated genes in Rep-MG and Rep-Mo/MΦ, while the other terms related to immune functions and other biofunctions were different between Rep-MG and Rep-Mo/MΦ, indicative of significantly different immune responses to brain injury between MG and MΦ. …”
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Clinical and genetic parallels in congenital brain lesions without epilepsy by P. L. Sokolov, A. G. Prityko, N. V. Chebanenko, P. A. Romanov

“…The pathogenesis involves genetically determined disorders of cell division and neuroontogenesis (neuronal migration, sprouting, myelination, partly apoptosis), cell metabolism, including those whose disturbance leads to the formation of storage diseases, transmembrane transport, the exchange of neurotransmitters and the functioning of synapses, the formation of and the functioning of the cytoskeleton, as well as the regulation of immunity and oncogenesis. …”
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EarthRanger: An open‐source platform for ecosystem monitoring, research and management by Jake Wall, Jes Lefcourt, Chris Jones, Chris Doehring, Dan O'Neill, Dennis Schneider, Jordan Steward, Joshua Krautwurst, Tiffany Wong, Bruce Jones, Karen Goodfellow, Ted Schmitt, Kathleen Gobush, Iain Douglas‐Hamilton, Frank Pope, Eric Schmidt, Jonathan Palmer, Emma Stokes, Andrea Reid, L. Mark Elbroch, Peter Kulits, Catherine Villeneuve, Victor Matsanza, Geoff Clinning, Jordi vanOort, Kristen Denninger Snyder, Alina Peter Daati, Wesley Gold, Stephen Cunliffe, Batian Craig, Barry Cork, Grant Burden, Marc Goss, Nathan Hahn, Sarah Carroll, Eric Gitonga, Ray Rao, Jared A. Stabach, Frédéric Dulude‐de Broin, Patrick Omondi, George Wittemyer

“…EarthRanger consists of seven main components (Core Server, API, Storage, Gundi, Web App, Mobile App, Ecoscope) that provide functionality for data (i) aggregation & collection, (ii) storage & management, (iii) real‐time and post hoc analysis, (iv) visualisation and (v) dissemination. …”
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Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development by Tingting Zhou, Ningbo Huangfu, Li Wang, Junyu Luo, Jinjie Cui, Xiangzhen Zhu, Sumei Wan, Xueke Gao

“…A total of 31 fatty acids (11 SFAs, 9 MUFAs, 11 PUFAs) were identified by targeted fatty acid detection, exhibiting a notable variation across development notably, PUFAs remained consistently dominant throughout all stages, suggesting their essential role in parasitoid growth. Correlation analysis further indicated that α-ketoglutaric acid and glutamic acid were functionally associated with fatty acids, serving as potential developmental biomarkers.DiscussionThis study presented the first comprehensive metabolomic atlas of L. japonica development, uncovering nutrient allocation strategies that synchronize with its life cycle. …”
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Theaflavins enhances laying hen production performance and egg antioxidant capacity via improving antioxidant status and regulating lipid metabolism by Ling Zhou, Pinyao Zhao, Jinwei Zhang, Jie Zhong, Yulin Rao, Jia Tang, Longsheng Jiang, Fen Chen, Lijuan Chen, Keying Zhang, Weimin Ouyang, Jialong Peng

“…Each treatment consisted of eight replicates of 16 birds, and the experiment lasted for 8 weeks. Data were analyzed using one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test, with quadratic polynomial contrasts applied to evaluate dose-response relationships.ResultsResults showed that TF supplementation quadratically increased (p < 0.05) egg production, egg yolk color, serum total antioxidant capacity (T-AOC), hepatic T-AOC, uterine T-AOC, hepatic superoxide dismutase activity, serum total cholesterol (TC), hepatic TC, hepatic triglycerides, and the expression of antioxidant-related and lipid metabolism-related genes. …”
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A Unified Framework for Fault and Performance Prediction Using Spatio-Temporal Geometric Features Based on STSFE by Dong-Hyun Kang, A-Youn Yang, Jong-Min Lee, Jong-Gu Lee

“…All models employ a multi-branch neural architecture that integrates MLP, CNN, and attention mechanisms, along with customized loss functions designed to enhance sensitivity to tail-zone deviations. …”
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Chest Compression Skill Evaluation System Using Pose Estimation and Web-Based Application by Ryota Watanabe, Jahidul Islam, Xin Zhu, Emiko Kaneko, Ken Iseki, Lei Jing

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Artificial Intelligence in Virtual Screening: Transforming Drug Research and Discovery—A Review by Sayantani Roy, Karuppiah Nagaraj, Amit Mittal, Flora C. Shah, Kaliyaperumal Raja

“…Additionally, CHARMM software was applied for molecular dynamics simulations to calculate empirical energy functions. AI-driven algorithms such as KarmaDock and DeepDock were utilized for large-scale ligand screening and for improving protein–ligand docking accuracy. …”
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Spatiotemporal Coupling of New-Type Urbanization and Ecosystem Services in the Huaihe River Basin, China: Heterogeneity and Regulatory Strategy by Muyi Huang, Qin Guo, Guozhao Zhang, Yuru Tang, Xue Wu

“…In this work, we revealed the evolution mechanism of coupling coordination development degree (CCD) between ESs and new urbanization and its driving factors in the Huaihe River Basin (HRB) from 1980 to 2020 using a combination of the CCD model, Exploratory Spatial Data Analysis (ESDA) method, and GeoDetector model. …”
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Innate lymphoid cells in bone marrow and peripheral blood of healthy individuals and in bone marrow of patients with myelodysplastic syndromes by Laiz C. Bento, Guilherme Martelossi Cebinelli, Nydia Strachman Bacal, Luciana Cavalheiro Marti

“…IntroductionInnate lymphoid cells (ILCs) are a recently characterized subset of lymphocytes with critical effector and regulatory functions. Based on distinct phenotypic markers and cytokine secretion profiles, ILCs are classified into three subtypes: ILC1, ILC2, and ILC3. …”
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Profiles of immune infiltration in colorectal cancer and their clinical significant: A gene expression‐based study by Yongfu Xiong, Kang Wang, He Zhou, Linglong Peng, Wenxian You, Zhongxue Fu

“…However, previous work has not accounted for the diversity of functionally distinct cell types that make up the immune response. …”
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Cortical thickness deviations as biomarker for subtyping and prognosis in pediatric brainstem tumors by Heyuan Jia, Kaikai Wang, Peng Zhang, Mingxin Zhang, Yiying Mai, Congying Chu, Xuntao Yin, Lingzhong Fan, Liwei Zhang

“…Abstract Brainstem tumors exert profound effects on cortical organization and functionality across the whole brain. However, the precise implications of changes in cortical thickness (CTh) for patient stratification and prognostic assessment remain unclear. …”
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The mechanism of body appreciation influencing social anxiety in college students: A moderated mediation model by Jinwei Zhu, Zhenming Jiang, Yan Li, Yani Cai, Jiayu Chen

“…This study examines the impact of body appreciation on social anxiety among college students, focusing on the mediating role of social suspiciousness and the moderating role of self-congruency in the relationship between body appreciation and social suspiciousness. An analysis of data from 1161 questionnaires reveals that body appreciation is a significant negative predictor of social anxiety among college students. …”
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Development of a Multi-Channel Wireless Deep Brain Stimulation and Signal Acquisition System for Neurostimulation and Biomarker Monitoring by Chang-Lin Hu, Guan-Yi Lu, Pei-Ling Kang, Chien-Ju Li, Ming-Jhe Lin, Guan-Lun Li, Fang-Yi Su

“…The MitoPark transgenic mouse model was used to evaluate the effects of subthalamic nucleus (STN)-DBS on motor and cognitive functions in Parkinson’s disease. Behavioral assessments, including the Narrow Beam Walking Test, Open Field Task, and Novel Object Recognition Test, were conducted. …”
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Clinical and cost-effectiveness of teen online problem-solving for adolescents who have survived an acquired brain injury in the UK: protocol for a randomised, controlled feasibili... by Patricia Jane Vickery, Tamsin Ford, Fiona C Warren, Jenny Limond, Shari L. Wade, A Jeffery, Annie Hawton, Janet Smithson, Sarah Haworth, Anna-Lynne Ruth Adlam

“…Improved treatment during the acute phase has led to increased survival rates, although with life-long morbidity in terms of social and emotional functioning. This is the protocol for a feasibility randomised controlled trial with an embedded qualitative study and feasibility economic evaluation. …”
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Alternative splicing dynamics during gastrulation in mouse embryo by Wei Wang, Yu Zhang, Yuanyuan Zhai, Wuritu Yang, Yongqiang Xing

“…Subsequently, the dynamic expression of splicing factors (SFs) during gastrulation was characterized, while the expression patterns and functions of germ layer-specific SFs were identified. …”
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UPBD: Construction and Evaluation Methods of the Underwater Polarization Benchmark Dataset for Complex Scenarios by Haihong Jin, Shangle Yao, Hao Yao, Wenjie Zhang, Zhiguo Fan

“…To address this limitation, we propose the Underwater Polarization Benchmark Dataset (UPBD), which consists of three functionally distinct subsets designed to evaluate different aspects of underwater image restoration. …”
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Land Terminal in Logistic Transport Chain and COVID-19 Pandemic in Poland by Kuśmińska-Fijałkowska Aldona, Łukasik Zbigniew, Kozyra Jacek, Olszańska-Wesoły Sylwia, Krasiuk Daniel

“…It results from the research conducted in the real object and its analysis. COVID-19 pandemic had positive impact on the enterprise, which shows a list of data about the flow of cargos, which has increased during pandemic years in comparison with previous years in the segment of transport of containers, pandemic definitely had impact on interest of the clients in railway transport in the New Silk Road. …”
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Impact of Dietary Phytochemicals on Gut Microbiota and Intestinal Barrier Integrity – Nutritional Interventions and Their Role in Chronic Diseases Prevention by Klaudia Michalak, Kacper Janowski, Emilia Piotrowicz, Sandra Góras

“…Materials and Methods: The analysis was conducted based on data available in studies found in the PubMed database. …”
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Effect of multiorgan abdominal ischemic preconditioning on experimental kidney transplantation by Juan Cruz Abate, Ivana Ivanoff Marinoff, Nathalie Arnal, Mariana Machuca, Rodrigo Papa-Gobbi, Leandro Vecchio, Martín Rumbo, Pablo Stringa, Natalia Raquel Lausada

“…Conclusion: The findings indicated that the MAIP exerts a protective influence on the transplanted kidneys, functioning as an IRI-protective strategy and enhancing the parameters associated with renal graft functionality.…”
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