Isoliensinine Induces Ferroptosis in Urothelial Carcinoma Cells via the PI3K/AKT/HIF-1α Axis: Molecular Evidence from Next-Generation Sequencing by Yun-Chen Li, Hsuan-En Huang, Chia-Ying Yu, Ya-Chuan Chang, Shu-Yu Lin, Shao-Chuan Wang, Wen-Wei Sung

“…RNA sequencing analysis, performed to explain the underlying mechanisms, revealed a significant regulation of cell functions, including apoptosis, the cell cycle, hypoxia-inducible factor 1 (HIF-1) signaling, tumor necrosis factor (TNF) signaling, and ferroptosis. …”
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Floods’ Impact on Cities’ Critical Infrastructure: A Case Study on Dubai by Diaa Addeen Abuhani, Raghad Aldamani, Imran Zualkernan, Reem Alali, Himanshu Grover

“…Critical infrastructure is defined as the core health, safety, and security facilities that maintain key social functions at the time of an emergency. With the weather instability driven by the effects of climate change, many normally dry lands are facing an increase in rainfall-induced floods. …”
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Melatonin in the regulation of human life and its role in development pathology by A. V. Shilova, N. I. Ananyeva, N. Yu. Safonova, L. V. Lukina

“…The aim of our study was to research the literature data available for analysis of the melatonin role in the neurological and mental disorders origin. …”
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The smart city concept as a method of building urban resilience to threats: Evidence from Poland by Wioletta Sylwia Wereda, Natalia Moch, Andrzej Skwarski

“…Quantitative and qualitative research methods were used in the research process. The data for the analysis were obtained using a diagnostic survey (CAWI and CATI methods) using the questionnaire survey technique. …”
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Screening of native wild Salvia nemorosa populations for chemical compositions, antioxidant activity and UHPLC-HRMS profiling by Raheleh Moshari-Nasirkandi, Abolfazl Alirezalu, Hamid Reza Mohammaddoust Chamanabad, Jussara Amato, Hadi Alipour, Ali Asghari, Atefeh Moshari-Nasirkandi

“…Data analysis indicated that the quality and quantity of the chemical compounds, as well as their antioxidant functions, varied depending on habitat diversity. …”
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Franciscan Convent of the Virgin Mary in Solivar – its History and Book Culture / Františkánsky konvent Panny Márie v Solivare – jeho história a knižná kultúra by BALOGA, Martin, Miroslav Huťka

“…The journeys of the preserved books from their creator to their owner present the functioning of the book trade in Hungary and highlight the possibilities of replenishing the library. …”
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Bioinformatics reveal macrophages marker genes signature in breast cancer to predict prognosis by Ying Li, Xin Zhao, Qiang Liu, Yujie Liu

“…This study aims to develop a prognostic macrophage marker genes signature (MMGS).Methods Single cell RNA sequence data analysis was performed to identify macrophage marker genes in breast cancer. …”
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Metabolomic liquid biopsy dynamics predict early-stage HCC and actionable candidates of human hepatocarcinogenesis by Kornelius Schulze, Tim Daniel Rose, Lorenz Adlung, Manuela Peschka, Francesca Pagani, Joao Gorgulho, Thorben W. Fründt, Ismail Labgaa, Philipp K. Haber, Carolin Zimpel, Darko Castven, Arndt Weinmann, Teresa Garzia-Lezana, Moritz Waldmann, Thomas Renné, Hannah Voß, Manuela Moritz, Dorian Orlikowski, Hartmut Schlüter, Jan Baumbach, Myron Schwartz, Ansgar W. Lohse, Samuel Huber, Bruno Sangro, Rocio I.R. Macias, Laura Izquierdo-Sanchez, Jesus M. Banales, Henning Wege, Jens U. Marquardt, Augusto Villanueva, Josch Konstantin Pauling, Johann von Felden

“…In vitro knockdown confirmed a functional role in proliferation and migration, as exemplified for PYCR2. …”
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PCI-DB: a novel primary tissue immunopeptidome database to guide next-generation peptide-based immunotherapy development by Sven Nahnsen, Hans-Georg Rammensee, Cécile Gouttefangeas, Jonas S Heitmann, Juliane S Walz, Jens Bauer, Marcel Wacker, Annika Nelde, Jonas Scheid, Steffen Lemke, Marissa L Dubbelaar, Patrick Zimmermann, Naomi Hoenisch Gravel, Susanne Jung, Anna Dengler, Yacine Maringer, Sven Fillinger, Tatjana Bilich

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Molecular characterization and mapping of Fgf21 gene in a foodfish species asian seabass. by Le Wang, Jun Hong Xia, Xiao Jun Liu, Peng Liu, Zi Yi Wan, Gen Hua Yue

“…Exogenous recombinant FGF21 significantly suppressed the appetite of Asian seabass. Our data suggest that Fgf21 plays a role in energy regulation and acute phase response in Asian seabass, and may have different functions in fish and mammals. …”
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Exploring the Potential Regulatory Mechanisms of Mitophagy in Ischemic Cardiomyopathy by Li Z, Kong J, Xi S, Jin Z, Yang F, Zhu Z, Liu L

“…However, it is still uncertain how mitophagy related genes (MRGs) may affect the diagnosis of ICM.Patients and Methods: Data were obtained from public databases. Subsequently, mitochondria autophagy score-related genes (MSRGs) were obtained through Weighted Gene Co-expression Network Analysis (WGCNA). …”
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Quality of Life of Long-Term Hemodialysis Patients by A. E. Khrulev, E. S. Kudryavtseva, P. A. Egorova, A. D. Rodionova, S. N. Sorokoumova, O. V. Suvorova

“…A trend towards inter-group difference was also discovered as regards the scales of vitality (VT) (53.7±19.5 vs. 61.0±19.4), social functioning (SF) (72.5±18.0 vs. 79.5±23.5). Multiple regression analysis established inverse relationship between the patient’s physical health component (PH) and age (rs=-0.317, P<0.05).Conclusion. …”
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Technical note: High-frequency, multi-elemental stream water monitoring – experiences, feedbacks and suggestions from 7 years of running three French field laboratories (Riverlabs... by N. Brekenfeld, S. Cotel, M. Faucheux, C. Fourtet, Y. Hamon, P. Petitjean, A. Blanchouin, C. Bouillis, M.-C. Pierret, H. Henine, A.-C. Pierson-Wickmann, S. Guillon, P. Floury, O. Fovet

“…The critical aspects discussed here relate to (1) supply of the field laboratory – basic functioning of the pumping, filtration and analytical systems; (2) data quality control and assurance via maintenance services and operations; (3) data harmonization and coordination of the laboratory components; and (4) team structure, skills and organization. …”
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Transmitted Light Measurement to Determine the Local Structural Characteristics of Paperboard: Grammage, Thickness, and Fiber Orientation by Cedric W. Sanjon, Yuchen Leng, Marek Hauptmann, Peter Groche, Jens-Peter Majschak

“…Various distribution functions are compared, and the Pearson Type 3, log-normal, and gamma distributions are found to most accurately describe the grammage, thickness, and fiber orientation distributions. …”
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Understanding turnover in healthcare and welfare sectors of high-income countries: an umbrella review by Herlinde Wynendaele, Els Clays, Ellen Peeters, Yannai DeJonghe, Ann Van Hecke, Jeroen Trybou

“…Study quality was evaluated using AMSTAR 2, and a Corrected Covered Area analysis was conducted. Results The analysis included 37 studies with a total of 511 primary studies. …”
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Association Between Depressive Symptoms and Comorbidities Among Elderly Diabetic Individuals in China by Luyao Qiao, Xin Pan, Tianpei Li, Shouqin Yi, Zhenyu Tang

“…Our study aimed to investigate this relationship among elderly Chinese diabetic patients. Methods Data from the China Health and Retirement Longitudinal Study (CHARLS) in 2020 were utilized for the cross‐sectional analysis. …”
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PATHWAYS TO ENHANCING THE EFFICIENCY OF BUSINESS MANAGEMENT MECHANISMS IN HEALTHCARE by Nataliia Letunovska, Liliia Khomenko, Yevhen Chvankin

“…The development of proposals also incorporated comparative analysis data and the experience of leading countries in the field of blood donation, which made it possible to integrate best international practices into the national context. …”
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Effect of nano curcumin administration on IL-6 expression in placental organs and fetal weight exposed to stress during pregnancy in mice by Viski Fitri Hendrawan, Yudit Oktanella, Habib Syaiful Arif Tuska, Intan Firdha Olien Noor Al Ichsan

“…Giving nanocurcumin, which functions as an anti-inflammatory and antioxidant, is expected to reduce cortisol levels which increase during pregnancy. …”
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Photophysical Properties of 1,3-Diphenylisobenzofuran as a Sensitizer and Its Reaction with O₂ by Ștefan Stan, João P. Prates Ramalho, Alexandru Holca, Vasile Chiș

“…TD-DFT calculations have been performed using several density functionals and the 6-311+G(2d,p) basis set to calculate absorption/emission wavelengths, oscillator strengths, transition dipole moments, and radiative lifetimes. …”
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Society and Orthodox Church in the rear province during World War I (based on materials of the city of Tsaritsyn, Saratov Governorate) by Irina Litvinova, Olga Redkina

“…The authors have carried out documentary analysis of archival sources and printed materials by means of the method of collecting factual data contained in documents; the documents themselves served as the main source of information. …”
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