Use of a Designed Peptide Library to Screen for Binders to a Particular DNA G-Quadruplex Sequence by Keita Kobayashi, Noriko Matsui, Kenji Usui

“…We demonstrated a method to screen for binders to a particular G-quadruplex sequence using easily designed short peptides consisting of naturally occurring amino acids and mining of binding data using statistical methods such as hierarchical clustering analysis (HCA). …”
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Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding by Luiz Ladeira, Anouk Verhoeven, Jonas van Ertvelde, Jian Jiang, Alessio Gamba, Julen Sanz-Serrano, Tamara Vanhaecke, Harm J. Heusinkveld, Ramiro Jover, Mathieu Vinken, Liesbet Geris, Liesbet Geris, Liesbet Geris, Bernard Staumont

“…In this study, we introduce two Liver Physiological Maps (PMs); comprehensive and machine-readable graphical representations of the intricate mechanisms governing two major liver functions.MethodsTwo PMs were developed through manual literature curation, integrating data from established pathway resources and domain expert knowledge. …”
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Challenges issues and future recommendations of deep learning techniques for SARS-CoV-2 detection utilising X-ray and CT images: a comprehensive review by Md Shofiqul Islam, Fahmid Al Farid, F. M. Javed Mehedi Shamrat, Md Nahidul Islam, Mamunur Rashid, Bifta Sama Bari, Junaidi Abdullah, Muhammad Nazrul Islam, Md Akhtaruzzaman, Muhammad Nomani Kabir, Sarina Mansor, Hezerul Abdul Karim

“…According to the taxonomy, each deep learning model is discussed, encompassing its core functionality and a critical assessment of its suitability for imaging-based SARS-CoV-2 detection. …”
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STRUCTURE OF PERIODONTAL TISSUE DISEASES IN WORKERS OF AGRICULTURAL PRODUCTION IN THE OPEN AND COVERED SOIL by V.T. Dyryk

“…Thus, as a result of the analysis of structure of periodontal disease depending on experience, in working in the conditions of contact with pesticides, on the closed soil investigated: • it is lower frequency of occurrence of intact periodontium all analtube intervals than in working of open soil and not contacting with pesticides; • it is lower frequency of occurrence of the initial forms of the inflammation of periodontal tissues (2,2 times) relatively to the obtained data in persons of the main group and the comparison group (1.3 times); • it is lower the incidence of primary generalized forms of periodontitis in relation to data of the comparison group (1.4 times) for the same number examined, compared with the values of the core group; • large frequency of occurrence of advanced forms of generalized periodontitis: in 1.6 times more than obtained data in the main group and in 3.3 times more than obtained data in the comparison group. …”
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Active learning for advanced biodegradable film design by Yi Gao, Chengcheng Liu, Yang Zhao, Peng Zhao, Feihui Chen, Qinghai Li, Yanguo Zhang, Bin Yang, Hui Zhou

“…Through six iterations with 186 data points for three-target optimization and seven iterations with 166 data points for two-target modeling, a data-driven platform was established to accurately predict CMC film properties based on composition and autonomously identify optimal formulations for specific performance targets. …”
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Identification of core noncoding RNA-associated competing endogenous RNA networks in renal fibrosis via whole-transcriptome sequencing by Yizhen Chen, Meng Cheng, Rong Dai, Weili Wang, Yonghao Sang, Liuting Wei, Yilin Gao, Wei Zhang, Yiping Wang, Lei Zhang

“…Core ceRNA axes were validated with dual-luciferase assay, RNA fluorescence in situ hybridization, western blot, immunofluorescence, and immunohistochemistry. Enrichment analysis was performed to explore potential functions.Results Sequencing analysis revealed significant dysregulation of ncRNAs in all models compared to the normal group. …”
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Recent Advances in Vitamin E TPGS-Based Organic Nanocarriers for Enhancing the Oral Bioavailability of Active Compounds: A Systematic Review by Chee Ning Wong, Siew-Keah Lee, Yang Mooi Lim, Shi-Bing Yang, Yik-Ling Chew, Ang-Lim Chua, Kai Bin Liew

“…<b>Inclusion criteria:</b> Full-text articles published in English and relevant to TPGS, which featured organic materials, utilized an oral administration route, and included pharmacokinetic study, were included to the final review. <b>Data extraction and analysis:</b> Data selection was conducted by two review authors and subsequently approved by all other authors through a consensus process. …”
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AI in Medical Questionnaires: Innovations, Diagnosis, and Implications by Xuexing Luo, Yiyuan Li, Jing Xu, Zhong Zheng, Fangtian Ying, Guanghui Huang

“…AI technology has now been shown to have great promise in improving diagnostic accuracy, assisting clinical decision-making, and simplifying questionnaire development and data analysis. To systematically assess the value of AI in medical questionnaires, this study searched 5 databases (PubMed, Embase, Cochrane Library, Web of Science, and China National Knowledge Infrastructure) for the period from database inception to September 2024. …”
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Sex differences in cardiorespiratory control under hypoxia: the roles of oxygen desaturation and hypoxic exposure time by André Luiz Musmanno Branco Oliveira, Gabriel Dias Rodrigues, Gabriel Dias Rodrigues, Bruno Moreira Silva, Philippe de Azeredo Rohan, Pedro Paulo da Silva Soares

“…IntroductionMales and females differ anatomically and functionally in cardiorespiratory regulation, with males tending to experience greater oxygen desaturation under hypoxia. …”
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Design and Development of Information Content of an Open Online School for Foreign Citizens in Russian by N. I. Gorodetskaya, I. E. Belotserkovskaya, T. V. Tumanova, N. B. Sherbakova

“…It is possible to judge the relevance of this resource on the basis of the statistical data obtained about the participants of online courses and the analysis of their reflexive reviews.Conclusion. …”
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Assessment of awareness about epilepsy amongst students of the volgograd state medical university and estimation of epilepsy stigmatization by O. V. Belyaev, E. A. Zharkina, T. I. Konovalova

“…A total of 508 students of medical and pediatric faculties of the VolSMU participated in the anonymous survey. Statistical data analysis was performed using Microsoft Excel. …”
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IDENTIFICATION OF FAULT CONTINUITY AND HOT WATER RESERVOIR USE SCHLUMBERGER CONFIGURATION RESISTIVITY METHOD IN CANGAR by Dhony Widyasandy, Aulia K Nugraha, Husni Cahyadi Kurniawan, Ahmad Luthfin

“…Data acquisition is carried out using 3 tracks with 10 sounding points. …”
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Modern health care priorities for workers of nuclear and radiation dangerous industry by I. R. Syomin, A. A. Vasilyev, I. Yu. Trufanova, I. I. Kurbat, Z. M. Bulasheva, T. A. Starodumova

“…There has been made an analysis of medical statistics data of the Central health department No 81 for the period of 1951-2001 and of results of psychophysiologic examination of workers in SCC nuclear- and radiation-hazardous areas. …”
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The agricultural and historical origin of an urban green infrastructure: Madrid-Río by Iván González-Truco, Eva J. Rodríguez-Romero, Rocío Santo-Tomás-Muro, Benito Jiménez-Alcalá

“…The methodology used combines the analysis of historical cartography, with historical data and own analytical planimetry. …”
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Z-scores outperform similar methods for analyzing CRISPR paralog synthetic lethality screens by Juihsuan Chou, Nazanin Esmaeili Anvar, Reem Elghaish, Junjie Chen, Traver Hart

“…Abstract Genetic screens offer a promising strategy for identifying tumor-specific therapeutic targets, but single-gene knockout screens often miss functionally redundant paralogs. Multiplex Cas9 and Cas12a CRISPR systems have been deployed to assay genetic interactions, but analysis pipelines vary considerably. …”
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Colder environments are associated with a greater cancer incidence in the female population of the United States by Ankit Sharma, Tanu Sharma, Mahaveer S Panwar, Devesh Sharma, Rashmi Bundel, Ryan T Hamilton, James A Radosevich, Chandi C Mandal

“…Similarly, environmental temperature modulates many biological functions. To study the effect of environment temperature on cancer incidence, the US population was selected. …”
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Liver-expressed antimicrobial peptide 2 is a hepatokine regulated by ghrelin, nutrients, and body weight by Md Nurul Islam, Hiroki Nabekura, Hiroaki Ueno, Takahiro Nishida, Atsushi Nanashima, Hideyuki Sakoda, Weidong Zhang, Masamitsu Nakazato

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Can education heal? Staff and students exploring reparative pedagogies in the context of institutional harms in higher education by Havva Görkem Altunbas, Xiaoyan Guo, Yuncong Liu, Helen Knowler, Tor Wright

“…Reckoning with historic and contemporary harms in educational contexts is under-theorised in learning development literature. Situating our analysis within what ​Zembylas (2015)​ and others have called the ‘affective turn’, we follow ​Sriprakash’s (2023)​ theorising of the reparative functions of education exploring the ways that reparative pedagogies can be harnessed, particularly by those higher education institutions that have acknowledged histories and legacies of harm. …”
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Assessing the Effect of SNPs on Litter Traits in Pigs by Lyubov V. Getmantseva, Siroj Yu Bakoev, Varvara S. Shevtsova, Anatoly Yu Kolosov, Neckruz F. Bakoev, Maria A. Kolosova

“…In general, the data obtained help to explain the genetic mechanisms of reproductive traits.…”
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T cell‐expressed Ift88 is required for proper thymocyte differentiation in mice by Sarah J. Miller, Nancy M. Gonzalez, Morgan E. Smith, Mandy J. Croyle, Bradley K. Yoder, Kurt A. Zimmerman

“…Abstract Intraflagellar transport protein 88 (Ift88) is required for the formation of cilia in the thymus and non‐ciliary dependent functions including T cell immune synapse formation. …”
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