Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di... by Rui Wang, Jessie P. Bakker, Ronald D. Chervin, Susan L. Garetz, Fauziya Hassan, Stacey L. Ishman, Ron B. Mitchell, Michael G. Morrical, Syed K. Naqvi, Jerilynn Radcliffe, Emily I. Riggan, Carol L. Rosen, Kristie Ross, Michael Rueschman, Ignacio E. Tapia, H. Gerry Taylor, David A. Zopf

“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
Get full text

GULP. II. Hierarchical Distribution and Evolution of Young Stellar Structures in NGC 4449 by Beena Meena, Elena Sabbi, Peter Zeidler, Bruce G. Elmegreen, Jan J. Eldridge, Varun Bajaj, Mario Gennaro, Anna Pasquali, Debra M. Elmegreen, Ralf S. Klessen, Linda J. Smith, Luciana Bianchi, Aida Wofford, Pietro Facchini, John S. Gallagher III, Daniela Calzetti, Eva K. Grebel, Angela Adamo, (GULP)

“…An age-dependent two-point correlation function (TPCF) analysis shows that young stars exhibit a strong hierarchical distribution, with clustering strength decreasing over time. …”
Get full text

BANNER ADVERTISING OF A PHARMACEUTICAL PRODUCT IN UKRAINIAN ONLINE MEDIA by Yevhen Seliukh

“…The main tasks of the research are to conduct a theoretical review of scientific sources, to consider the specifics of banner advertising in the pharmaceutical segment, to perform an experimental analysis of data from a banner campaign promoting an antiviral drug, and to evaluate the effectiveness of a real banner advertising campaign in Ukrainian online media. …”
Get full text

Main trends of the international market of educational services by T. I. Chinaeva

“…The analysis of analytical and statistical information on the processes happening in this area, both at the international level, and in Russia is the basis.In the course of the research the methods of the analytical and logical analysis on the basis of statistical data promoting more detailed studying of dynamic and structural changes of the social and economic phenomena and processes were used.In general for the last 30 years the extent of the international student’s mobility increased more than by 6 times. …”
Get full text

Evidence to shared genetic correlation of ischemic stroke and intracerebral hemorrhage and cardiovascular related traits. by Wei He, Jiajia Shi, Yiming Qian, Tao Fan, Xuehong Cai, Haochang Li, Peng Huang, Qin Shi

“…In addition, we also performed Transcriptome-wide association (TWAS) analysis and fine-mapping for each phenotype to functionally annotate significant loci.…”
Get full text

Exploring the Role of Visual Representation Signals for Interactional Action in Conversation by Arash Gholamy Saleh Abady, Sayyed Mohammad Alavi

“…The main approach to conversation analysis is multimodal analysis, which can be explained by the distinction between the non-verbal and verbal expression in the communicative functions (Haddington & Kääntä, 2011; Streeck et al., 2011). …”
Get full text

Autonomous Vehicle Acceptance in China: TAM-Based Comparison of Civilian and Military Contexts by Dan Wan, Ling Peng

“…Also, a structured questionnaire was designed, with 1004 valid responses received from a sample comprising mainly members of the Chinese public aged 31–50. Data analysis was conducted through reliability and validity tests, correlation analysis, and Structural Equation Modeling (SEM). …”
Get full text

Atypical cancer risk profile in carriers of Italian founder BRCA1 variant p.His1673del: Implications for classification and clinical management by Giovanni Innella, Cristina Fortuno, Laura Caleca, Bing‐Jian Feng, Courtney Carroll, Michael T. Parsons, Sara Miccoli, Marco Montagna, Daniele Calistri, Laura Cortesi, Barbara Pasini, Siranoush Manoukian, Daniela Giachino, Laura Matricardi, Maria Cristina Foti, Valentina Zampiga, Claudia Piombino, Elena Barbieri, Francesca Vignolo Lutati, Jacopo Azzolini, Rita Danesi, Valentina Arcangeli, Sandrine M. Caputo, Nadia Boutry‐Kryza, Vincent Goussot, Susan Hiraki, Marcy Richardson, Hereditary Breast/Ovarian Cancer IOV network (HBOC IOVnet), Simona Ferrari, Paolo Radice, Amanda B. Spurdle, Daniela Turchetti

“…Likelihood‐ratio in favor of pathogenicity was 98898642.82 under assumption of standard BRCA1 breast and ovarian penetrance, and 104240832.84 after excluding breast cancer diagnoses (based on penetrance results). Functional analysis demonstrated that the variant abrogates the BRCA1‐ABRAXAS1 binding, supporting the PS3 code assignment within the ACMG/AMP rule‐based model. …”
Get full text

Left atrial single-cell transcriptomics reveals amphiregulin as a surrogate marker for atrial fibrillation by Yuya Suzuki, Takuo Emoto, Shunsuke Sato, Takeshi Yoshida, Mitsuhiko Shoda, Hiromi Endoh, Manabu Nagao, Tomoyo Hamana, Taishi Inoue, Tomohiro Hayashi, Eriko Nitta, Hiroki Konishi, Kunihiko Kiuchi, Mitsuru Takami, Kimitake Imamura, Masayuki Taniguchi, Masatoshi Inoue, Toshihiro Nakamura, Yusuke Sonoda, Hiroyuki Takahara, Kazutaka Nakasone, Kyoko Yamamoto, Kenichi Tani, Hidehiro Iwai, Yusuke Nakanishi, Shogo Yonehara, Atsushi Murakami, Ryuji Toh, Takenao Ohkawa, Tomoyuki Furuyashiki, Ryo Nitta, Tomoya Yamashita, Ken-ichi Hirata, Koji Fukuzawa

“…This study aims to identify the monocyte–macrophage heterogeneity and interactions of these cells with non-immune cells, and to identify functional biomarkers in patients with AF. Therefore, we assess the single cell landscape of left atria (LA), using a combination of single cell and nucleus RNA-seq. …”
Get full text

Prediction of menstrual recovery patterns in premenopausal women with breast cancer taking tamoxifen after chemotherapy: an ASTRRA Substudy by Young Joo Lee, Woo Chul Noh, Sungchan Gwark, Hyun-Ah Kim, Jai Min Ryu, Seung Il Kim, Eun-Gyeong Lee, Seock-Ah Im, Yongsik Jung, Min Ho Park, Kyong Hwa Park, Su Hwan Kang, Joon Jeong, Eunhwa Park, Sung Yong Kim, Min Hyuk Lee, Lee Su Kim, Woosung Lim, Seonok Kim, Hee Jeong Kim

“…Methods In the ASTRRA trial, patients who resumed ovarian function within 2 years after chemotherapy were randomized to receive tamoxifen for 5 years or OFS with tamoxifen for 2 years. …”
Get full text

CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling by Qun Zhao, Jingyi Wu, Mengyuan Feng, Anjie Zhang, Liwei Fu, Jinglin Chen, Lian Li, Fangzhou Li, Tingting Li, Shu Jin, Shengbao Li, Xianjun Yu

“…Overall, our findings revealed a novel function of CXCL13 in negatively regulating liver regeneration. …”
Get full text

Updated Japanese multicenter registry study evaluates the efficacy and safety of proton beam therapy for treating extrahepatic cholangiocarcinoma by Hideya Yamazaki, Kei Shibuya, Takuya Kimoto, Motohisa Suzuki, Masao Murakami, Kazuki Terashima, Tomoaki Okimoto, Takashi Iizumi, Hideyuki Sakurai, Masaru Wakatsuki, Takashi Ogino, Takeshi Arimura, Masaru Takagi, Masayuki Araya, Takahiro Waki, Sae Matsumoto, Hiroyuki Ogino, Norio Katoh, Takayuki Hashimoto, Hidehiro Hojo, Nobuyoshi Fukumitsu, Takumi Fukumoto, Masayuki Ohtsuka

“…. ≥ 3 cm (p = 0.015); liver function Child–Pugh score normal/A vs. B/C (p < 0.001); and distance of the tumor from the gastrointestinal tract > 2 cm vs. ≤ 2 cm (p = 0.008) in multivariate analysis. …”
Get full text

Genetic interaction between oxidative stress and body mass index in a Spanish population by Francisco Lara-Hernández, Rebeca Melero, María Elena Quiroz-Rodríguez, Celeste Moya-Valera, Mariana de Jesús Gallardo-Espinoza, Luis Álvarez, Ingrid Lizeth Valarezo-Torres, Laisa Briongos-Figuero, Jessica Abadía-Otero, Francisco Javier Mena-Martin, Guillermo Saez, Josep Redon, Juan-Carlos Martín-Escudero, Ana-Bárbara García-García, Guillermo Ayala, Felipe Javier Chaves

Get full text

Utilizing Nanopore direct RNA sequencing of blood from patients with sepsis for discovery of co- and post-transcriptional disease biomarkers by Jingni He, Devika Ganesamoorthy, Jessie J.-Y. Chang, Jianshu Zhang, Sharon L. Trevor, Kristen S. Gibbons, Stephen J. McPherson, Jessica C. Kling, Luregn J. Schlapbach, Antje Blumenthal, Lachlan J. M. Coin, RAPIDS Study Group

“…Gene ontology gene set enrichment analysis of poly(A) tail length revealed enrichment of long tails in mRNA of genes involved in signaling and short tails in oxidoreductase molecular functions. …”
Get full text

Exploring Individuals’ Views and Feedback on a Nutritional Screening Mobile App: Qualitative Focus Group Study by Debra Jones, Anne Marie Sowerbutts, Sorrel Burden

“…MethodsWe performed a qualitative study using deductive and inductive framework analysis. A series of online focus groups (~1 hour each) were conducted, exploring potential users’ views on the app’s content design, functionality, and usefulness, which was set in demonstration mode and not available for direct use with patients. …”
Get full text

The Impact of Parental Support on Adherence to Therapist-Assisted Internet-Delivered Acceptance and Commitment Therapy in Primary Care for Adolescents With Anxiety: Naturalistic 12... by Anna Larsson, Sandra Weineland, Linnea Nissling, Josefine L Lilja

“…Nevertheless, due to a small and gender-biased sample size with a large proportion of dropouts and missing data, a nonrandomized assignment of intervention, and an analysis limited to within group, this study should be considered an explorative evaluation rather than an outcome study.…”
Get full text

The ways to solve digital problems transformations in certain sectors of the economy at the present stage by P. Yu. Chaplinskaya, E. V. Karpichev, G. V. Alekseev

“…The study is based on the analysis of statistical data provided in the materials of Rosstat for the period 2016-2022. …”
Get full text

Translation and psychometric evaluation of the Chinese version of the mathematical resilience scale by Xia Wang, Amalia bt Madihie, San Nah Sze

“…s (2000) guidelines, with validity and reliability assessed through item analysis, reliability analysis, validity analysis, item response theory, and differential item functioning. …”
Get full text

Principle of Thematic Correspondence in Dialogue of Official Letters (on Material of Citizens’ Appeals and Responses to Them) by T. V. Matveeva, M. A. Shirinkina

“…The preliminary stage of the analysis identifies and schematizes the composition of the thematic chains of the initial and response letters; the main stage is related to the comparison of the data obtained. …”
Get full text

The role of information skewness in shaping extremist content: A look at four extremists by Waseem Afzal

“…Six categories of religion, ideology, politics-history, cognition, affection, and conation provided the framework used to analyse and deductively categorise the data using content analysis. The affective lexicon developed by Ortony et al. (1987) was used to identify words belonging to the categories of cognition, affection (emotions and feelings), and conation (behaviour/actions). …”
Get full text