Diversity and distribution of nitrifying bacteria play an important role in the nitrogen cycle in mangrove sediments by A. Mubaraq, M. Sembiring, E. Widiastuti, E. Fachrial, B. Utomo, M. Turjaman, F. Sidik, Y.I. Ulumuddin, V.B. Arifanti, E.S. Siregar, T. Kajita, S. Proches, M. Basyuni

“…The primary objective of this study is to provide comprehensive analysis of nitrifying bacteria in mangrove sediments by conducting a systematic review. …”
Get full text

Single-cell sequencing on PBMCs from patients with HA and HB with inhibitors reveals different immune responses to FVIII and FIX by Enhao Li, Zekun Li, Jinzeng Wang, Haoyang Wu, Yilun Xue, Can Lou, Zhenping Chen, Feng Liu, Wenman Wu, Qiulan Ding, Runhui Wu, Xuefeng Wang, Jing Dai

“…After quality control, a total of 75 051 cells were clustered into 19 subsets. Transcriptome analysis revealed differences in the composition of lymphocyte subsets and the functional status of immune cells between the HA and HB groups. …”
Get full text

TLR3-overexpressing umbilical cord mesenchymal stromal cells suppress immune responses to attenuate high-risk corneal transplantation rejection by Yaqi Cheng, Huaxin Chen, Simin Gu, Weihua Li, Huan Yu, Jianqiang Zhang, Huini Zhang, Jiayi Lin, Haocheng Zhu, Youyu Liu, Wenqiong Li, Ting Fu, Haoyu Zeng, Tao Wang, Shiqi Ling

“…Increased numbers of Tregs and decreased numbers of Th17 cells were observed in UC-MSC-treated corneas. An analysis of the GSE68610 dataset revealed that TLR3 expression was upregulated in cytokine-activated UC-MSCs, suggesting that TLR3 is a potential regulator of the immunosuppression function of UC-MSCs. …”
Get full text

Factors associated with the intermediate probability of heart failure with preserved ejection fraction on the H₂FPEF score in asymptomatic patients in rotation work cond... by A. S. Vetoshkin, N. P. Shurkevich, A. A. Simonyan, L. I. Gapon, M. A. Kareva

“…SF-36 questionnaire revealed intergroup differences only on the role functioning scale (p=0,013) with lower values in group 2. …”
Get full text

The SIRT1 activator SRT2104 exerts exercise mimetic effects and promotes Duchenne muscular dystrophy recovery by Matteo Giovarelli, Silvia Zecchini, Silvia Rosanna Casati, Laura Lociuro, Oriola Gjana, Luca Mollica, Elena Pisanu, Harcel Djaya Mbissam, Ornella Cappellari, Chiara De Santis, Alessandro Arcari, Anne Bigot, Giuditta Clerici, Elisabetta Catalani, Simona Del Quondam, Annapaola Andolfo, Clarissa Braccia, Maria Grazia Cattaneo, Cristina Banfi, Dario Brunetti, Emanuele Mocciaro, Annamaria De Luca, Emilio Clementi, Davide Cervia, Cristiana Perrotta, Clara De Palma

Get full text

Financial Toxicity and Kidney Disease in Children and Adults: A Scoping Review by Siligato R, Gembillo G, De Giorgi A, Di Maria A, Scichilone LM, Capone M, Vinci FM, Nicoletti S, Bondanelli M, Malaventura C, Storari A, Santoro D, Dionisi S, Fabbian F

“…Health care professionals need to improve their knowledge about the relationship between FT and renal disease; there is a paucity of data regarding the effects of FT on different outcomes, although this nonmedical risk factor can negatively influence kidney health and quality of life. …”
Get full text

Mutations in ampD cause hyperproduction of AmpC and CmcB β-lactamases and high resistance to β-lactam antibiotics in Chromobacterium violaceum by Luís Gustavo Laranjeiro, Carlos Eduardo M. Neme, Maristela Previato-Mello, Bianca B. Batista, Isabel Henriques, José F. da Silva Neto

“…Remarkably, AmpD1 possesses a unique N-terminal acetyltransferase domain, suggesting a distinct functional mechanism for this enzyme. Our work offers an explanation for the limited effectiveness of many β-lactams in treating C. violaceum infections. …”
Get full text

Postoperative Sore Throat After Tracheal Intubation: An Updated Narrative Review and Call for Action by Chen Z, Zuo Z, Zhang L, Gong M, Ye Y, Jin Y, Zhao X

“…Two groups of reviewers independently performed data search and cleaning after standard training. …”
Get full text

Epidemiological aspects of nephrolithiasis and chronic diseases of the cardiovascular system combination by R. V. Royuk, S. K. Yarovoy, N. A. Guseva, Sh. L. Voskanyan, V. V. Royuk, D. B. Rodin

“…The obtained data was analyzed using descriptive statistics methods.Results. …”
Get full text

Incidence, causes and prognostic outcomes of acute coma: a nationwide population-based retrospective cohort study in Taiwan by Chih-Ching Liu, Chih-Yuan Lin, Yue-Chune Lee, Jen-Feng Liang, Mingche Tsai, Meng-Ling Chang

“…Secondary outcomes assessed were reversible coma, hospitalisation rates, 30-day mortality, 1-year medical utilisation and long-term functional outcomes. Cox regression models identified factors influencing long-term mortality.Results The overall event rate for acute coma was 4.23 per 1000 ED visits, and the incidence rate was 0.93 per 1000 person-years. …”
Get full text

Novel post-translational modification learning signature reveals B4GALT2 as an immune exclusion regulator in lung adenocarcinoma by Ge Zhang, Zhenfa Zhang, Lianmin Zhang, Guangyao Zhou, Pengpeng Zhang, Dingli Wang, Shuai Jiang

“…Significantly, suppression of B4GALT2 was found to enhance CD8+ T lymphocyte populations and their functional status, thereby potentiating anti-programmed cell death protein 1 immunotherapeutic efficacy in animal studies. …”
Get full text

Analysing the contribution of trees and green spaces to household nutrition security in eThekwini, KwaZulu-Natal, South Africa by Qhelile Ntombikayise Bhebhe, Qhelile Ntombikayise Bhebhe, Muthulisi Siwela, Temitope O. Ojo, Temitope O. Ojo, Simphiwe Innocentia Hlatshwayo, Simphiwe Innocentia Hlatshwayo, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi, Rob Slotow, Mjabuliseni S. C. Ngidi, Mjabuliseni S. C. Ngidi, Mjabuliseni S. C. Ngidi

Get full text

The Influence of Zero‐Profile Implant Selection on the Outcomes of Anterior Cervical Discectomy and Fusion by Xing‐Jin Wang, Jun‐Bo He, Ting‐Kui Wu, Bei‐Yu Wang, Xin Rong, Quan Gong, Hao Liu

“…In addition, radiographical analysis encompassed cervical lordosis (CL), functional spinal unit (FSU) angle, range of motion (ROM) of the total cervical spine and the FSU, anterior and posterior FSU height, C1–C7 sagittal vertical axis (SVA), C2–C7 SVA, the center of gravity of the head (CGH)‐C7 SVA as well as T1 slope (T1S) measurements. …”
Get full text

CO13 | Genetic background in hypercholesterolemic patients framing cardiovascular risk

“…Among adults, LDL-cholesterol levels were comparable between LDLR-positive and LDLR-negative group, whereas in younger subjects significantly higher LDL-cholesterol levels were observed among LDLR-positive.As concerns DLCN score, performed in adult population, significantly higher values in subjects carrying LDLR mutation were found. Conclusions: Present data suggest the involvement of multiple loci beyond LDLR gene in the modulation of lipid profile, as well as cardiovascular risk.Nevertheless, the expansion of genetic analysis to a largest cohort might allow a better comprehension of the role of further major/modifier genes, as well as of accumulation of common small- effect LDL-C raising alleles in determining LDL-C levels and cardiovascular events. …”
Get full text

Novel pyrochlores in the Bi2O3–MgO–Ta2O5 (BMT) system: Synthesis optimisation, phase equilibria and dielectric properties by K.B. Tan, P.Y. Tan, Y. Feng, C.C. Khaw, V. Raman, H.C. Ananda Murthy, R. Balachandran, S.K. Chen, O.J. Lee, K.Y. Chan, D. Zhou, M. Lu

Get full text

The role of fruit trees in reducing food insecurity and improving nutrition security of rural households: A case study of the KwaZulu-Natal province, South Africa by Fortunate Nosisa Zaca, Unity Chipfupa, Temitope Oluwaseun Ojo, Lavhelesani Rodney Managa, Tafadzwanashe Mabhaudhi, Rob Slotow, Mjabuliseni Simon Cloapas Ngidi

Get full text

THE ROLE AND SIGNIFICANCE OF COSTEN’S SYNDROME IN DYSFUNCTIONAL CONDITIONS OF THE TEMPOROMANDIBULAR JOINTS by V.F. Makeev, U.D. Telishevska, O.D. Telishevska, M.Yu. Mykhailevych

“…A child who begins to hold the head, the functional activity of the extensors and flexors of the neck gradually increases synchronously with the muscles of the floor of the mouth and masticatory muscles, combining their activity around the virtual axis of the paired temporomandibular joint. …”
Get full text

LEO or LEO baby within enterprise overlapping stents combined with coil embolization treatment for ruptured vertebrobasilar artery dissecting aneurysms by Zengbao Wu, Minghui Zhou, Ali Abdi Maalim, Yang Han, Xiao Guo, Cao Chen, Ting Lei, Kai Shu, Mingxin Zhu

“…Patient characteristics, clinical outcomes, and radiological results were thoroughly reviewed. Functional data were evaluated using the modified Rankin scale (mRS). …”
Get full text

Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations by Dan Li, Jianying Li, Donald J. Johann, Daniel Butler, Guangchun Chen, Jonathan Foox, Binsheng Gong, Wendell Jones, David P. Kreil, Rebecca Kusko, Paweł P. Łabaj, Anne Bergstrom Lucas, Christopher E. Mason, Christopher Mozsary, Natalia Novoradovskaya, Carlos Pabón-Peña, Bohu Pan, Todd A. Richmond, Roberta Maestro, Sayed Mohammad Ebrahim Sahraeian, Andreas Scherer, Hagen U. Tilgner, James C. Willey, Pierre R. Bushel, Joshua Xu

Get full text

PULMONARY-RENAL SYNDROME: DIFFICULTIES OF DIFFERENTIAL DIAGNOSIS by D. Yu. Andriyashkina, N. A. Demidova, N. A. Shostak, N. A. Tutaev, A. D. Ershov, D. K. Dudin

“…Chronic heart failure 2А, functional class IV. Mixed anemia (iron-deficient, chronic disease), severe. …”
Get full text