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16921
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16922
METTL3-mediated m<sup>6</sup>A modification of pri-miRNA-31 promotes hypertrophic scar progression
Published 2025-03-01“…Aberrant m<sup>6</sup>A modification patterns have been identified in HS; however, the expression of the methyltransferase, along with its function and molecular mechanisms in HS, remains unclear. …”
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16923
Elevated Ambient Temperature Associated With Increased Cardiovascular Disease–Risk Among Patients on Hemodialysis
Published 2024-10-01“…Methods: We conducted a retrospective analysis from 2011 to 2016 in the contiguous United States during warmer months among eligible patients on dialysis who were identified in the United States Renal Data System (USRDS). …”
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16924
Application of the implementation research logic model for evaluating a framework for disseminating arthritis-appropriate evidence-based interventions
Published 2025-08-01“…This study follows the implementation of the Framework through key stages: screening, brief advice and counseling, referral to hub, AAEBI selection and participation, outcomes measurement, and feedback of data to the clinic. This paper offers a practical example of the iterative process we used to make decisions for the evaluation, how the IRLM is used to guide decision-making and analysis, and the methods of our evaluation plan.…”
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16925
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16926
Dynamic shifts in trophoblast nucleos(t)ide metabolism, transport, and adenosine signaling during gestation and preterm birth
Published 2025-08-01“…Pearson’s correlation analysis revealed strong gene-metabolite and gene-gene associations, highlighting an integrated metabolic network regulating placental function. …”
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16927
Efficacy and safety of left bundle branch area pacing versus right ventricular apex pacing in patients with atrioventricular block: study protocol for a randomised controlled trial
Published 2021-06-01“…Therefore, the current study intends to address the paucity in RCT data evaluating LBBaP versus RVAP in AVB patients.Analysis and methods This study is a single-centre, randomised controlled superiority trial to be conducted at the Cardiac Centre of Beijing Anzhen Hospital. …”
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16928
Ultradeep N-glycoproteome atlas of mouse reveals spatiotemporal signatures of brain aging and neurodegenerative diseases
Published 2025-07-01“…Furthermore, the region-resolved brain N-glycoproteomes for Alzheimer’s Diseases, Parkinson Disease and aging mice reveal the spatiotemporal signatures and distinct pathological functions of the N-glycoproteins. A comprehensive database resource of experimental N-glycoproteomic data from this study and previous literatures is further established. …”
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16929
RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response
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16930
Contributions of contrast-enhanced ultrasound (CEUS) to a fetal–placental circulation study (EVUPACUS): a protocol for a prospective comparative study in a population of women unde...
Published 2025-08-01“…The statistical analysis will include descriptive analysis for all study patients, with quantitative data described by means±SDs, medians, IQRs, and extreme values and qualitative data reported as counts and percentages. …”
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16931
Legal and technological obstacles on the road to creating the 3D cadastre in Poland
Published 2018-09-01“…The last stage of the research work was an analysis of the compliance of spatial data, in terms of the consistency of objects registered in various databases of geodetic character. …”
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16932
Assessing barriers and opportunities for the improvement of laboratory performance and robust surveillance of antimicrobial resistance in Nigeria– a quantitative study
Published 2025-04-01“…Methods A cross-sectional study design utilising structured questionnaire administered online via Qualtrics and reported in accordance with strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Data analysis involved descriptive and inferential statistics as well as bivariate and multivariate logistics to test predictive analysis of relationship between variables. …”
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16933
Effectiveness of a school-based high-intensity interval training intervention in adolescents: study protocol of the PRO-HIIT cluster randomised controlled trial
Published 2024-10-01“…Therefore, a PRO-HIIT intervention will be conducted to evaluate the effectiveness of a 12-week school-based HIIT intervention on cardiorespiratory fitness, physical activity, body composition, muscular strength, bone health, cognitive function, wellbeing and academic performance among 12–13-year-olds.Methods and analysisEight classes of year 7 students (12–13-year-olds) from a secondary school in Ningbo, China, will be recruited and randomly allocated into an intervention or control group. …”
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16934
End-stage renal disease after renal cancer surgery: risk factors and overall survival
Published 2024-05-01“…Efforts to spare renal function, including nephron-sparing surgery and active surveillance in appropriate cases, are highly relevant to reduce the development of severe kidney dysfunction. …”
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16935
Influence of Ordinary Cigarettes and Their Substitute IQOS<sup>®</sup> on Secretory Immunoglobulin A in Unstimulated Saliva
Published 2025-06-01“…Smoking is known to negatively affect immune function, but data on the impact of heated tobacco products such as IQOS<sup>®</sup> on sIgA levels are limited. …”
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16936
Hemorrhagic disease of the newborn: modern approaches to diagnosis, prevention and treatment
Published 2023-10-01“…The incidence of hemorrhagic disease of the newborn varies in different regions of the world, in Russia, according to the literature data, it ranges from 0.25 to 1.7%. Hemorrhagic disease of the newborn is characterized by the development of bleeding and hemorrhage, which negatively affect the function and further development of a number of organs and systems of the child, especially the central nervous system and the gastrointestinal tract. …”
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16937
Social Determinants of Health‐Related Outcomes in an Intervention Following Initial Implantable Cardioverter‐Defibrillator Implantation
Published 2025-05-01“…Methods This secondary analysis used data from a comparative effectiveness randomized controlled trial of a post‐ICD patient intervention. …”
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16938
Frequency of synaptic antigen-specific CD4+ T cells in dementia is age-dependent but not correlated with cognitive impairment
Published 2025-06-01“…We investigated TH cell frequencies and phenotypes after antigen-reactive T cell enrichment (ARTE) using three important synaptic antigens known to play a role in cognitive function, N-Methyl-D-Aspartate receptor (NMDAR), Leucine-rich, glioma inactivated 1 (LGI1) and metabotropic glutamate receptor 5 (mGluR5). …”
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16939
Deciphering the causal landscape: genetic insights into sporadic vestibular schwannoma risk factors through Mendelian Randomization
Published 2024-12-01“…Abstract Background Sporadic vestibular schwannoma, a benign tumor affecting the vestibulocochlear nerve, poses significant health challenges due to its impact on hearing, balance, and facial nerve function. Despite known associations with genetic mutations and environmental factors, the causality between potential risk factors and sporadic vestibular schwannoma remains underexplored. …”
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16940
Divergent effects of monomethyl branched-chain fatty acids on energy metabolism and insulin signaling in human myotubes
Published 2025-03-01“…Branched-chain fatty acids (BCFAs) are predominantly saturated fatty acids with one or more methyl branches on the carbon chain, typically found in dairy products and measured in micromolar concentrations in human plasma. The biological function of BCFAs in humans remains ill-defined, but a relationship between circulating BCFAs and cardiometabolic health has been suggested. …”
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