Frailty and Mortality Risk Among Dogs with Extreme Longevity: Development and Predictive Validity of a Clinical Frailty Index in the Exceptional Aging in Rottweilers Study by David J. Waters, Aimee H. Maras, Rong Fu, Andres E. Carrillo, Emily C. Chiang, Cheri L. Suckow

“…Frailty refers to a state of increased vulnerability to mortality and other adverse outcomes as a consequence of age-related decline in physiologic reserve and function. Comparative biomedical scientists are relied upon to innovate approaches to enhance understanding of the similarities and differences between humans and other animal species that can impact healthy aging. …”
Get full text

Persistent thrombocytopaenia as an independent risk factor for 28-day mortality and multiorgan failure in exertional heatstroke: a retrospective study of 217 patients by Li Zhong, Yan Liu, Conglin Wang, Zheying Liu, Lei Su, Zhifeng Liu, Ming Wu

“…Nonsurvivors presented significantly worse liver/kidney function, coagulopathy (DIC incidence: 89.5% vs. 26.8%, p < 0.001), and AKI incidence (100% vs. 38.4%, p < 0.01). …”
Get full text

Outcomes of Early Weightbearing Following Open Reduction and Internal Fixation of Unstable Ankle Fractures in a Geriatric Population by Valerie Carbajal MD, Daniel Choi MD, Brent Kokobun MD, Arash Aminian MD, David Lee MD, Thomas Harris MD

“…There has been a growing trend towards early weightbearing due to its advantages in rehabilitation and return to function. Even so, a survey study revealed that physicians tend to increase the non-weightbearing period for their geriatric population. …”
Get full text

Heterogeneity of autoimmune diabetes mellitus in adults: real-world clinical practice by N. V. Rusyaeva, I. V. Kononenko, O. K. Vikulova, O. M. Smirnova, M. V. Shestakova

“…To investigate the heterogeneity of autoimmune diabetes mellitus (DM) in adults and identify factors associated with delayed initiation of insulin therapy in real-world clinical practice.MATERIALS AND METHODS. A retrospective analysis was conducted on clinical and laboratory data from 717 patients with DM onset after the age of 18 who were tested for antibodies against β-cell antigens (GAD, IA-2, ICA, ZnT8, insulin) at the National Medical Research Center for Endocrinology (NMRCE) between 2017 and 2022. …”
Get full text

PO70 | Clinical safety and monitoring of apixaban combined with tacrolimus and everolimus in kidney transplant patients: a prospective study

“…In one patient (Pt.1), measurements were taken during both 5 mg and 2.5 mg treatment periods. Data collected also included demographic and clinical information, indications for anticoagulation, tacrolimus and everolimus plasma concentrations, average tacrolimus and everolimus plasma concentrations over the last year, hemoglobin levels, renal function, and the safety profile (major/minor bleeding, cardioembolism, or VTE). …”
Get full text

Women-specific reference ranges for serum TSH in Liguria: the impact of age and year of collection in a single-center cross-sectional study by Massimo Giusti, Marilena Sidoti

“…Abstract Background TSH is the first-line test of thyroid function, and the normal TSH references provided by manufacturers are generally used in diagnoses. …”
Get full text

Prediction of 12-month exacerbation-related readmission in hospitalized patients with COPD: a single-center study in China by Cong Zhang, Wenhao Ling, He Pan, Hongxia Tan, Li He

“…Abstract Background Patients with chronic obstructive pulmonary disease (COPD) who are hospitalized multiple times for exacerbations face substantially worse clinical outcomes, including higher mortality, faster lung function decline, and reduced quality of life. Identifying these high-risk individuals is essential for early intervention and improved disease management. …”
Get full text

Enhancing Predictive Tools for Skeletal Growth and Craniofacial Morphology in Syndromic Craniosynostosis: A Focus on Cranial Base Variables by Lantian Zheng, Norli Anida Abdullah, Norlisah Mohd Ramli, Nur Anisah Mohamed, Mohamad Norikmal Fazli Hisam, Firdaus Hariri

“…<b>Background/Objectives</b>: Patients with syndromic craniosynostosis (SC) pose a significant challenge for post-operational outcomes due to the variability in craniofacial deformities and gain-of-function characteristics. This study aims to develop validated predictive tools using stable cranial base variables to predict changes in the midfacial region and explore the craniofacial morphology among patients with SC. …”
Get full text

A study on land use change simulation based on PLUS model and the U-net structure: A case study of Jilin Province by Jiafu Liu, Xiangli Kong, Yue Zhu, Baihao Zhang

“…The U-Net model, which utilizes convolutional neural networks to extract multi-scale spatial features and addresses the class imbalance issue with the OHEM-Dice composite function, significantly enhances the prediction accuracy of nonlinear dynamics. …”
Get full text

Community structure and diversity of myxobacteria in soils from Inner Mongolia, China by Zhihua Wu, Zhihua Wu, Songyuan Li, Xuehan Wang, Xuehan Wang, Huirong Liu

“…The completion of this work can provide basic data for the in-depth study of myxobacteria in the soil.…”
Get full text

Hypoxic Conditioning in Rehabilitation and Secondary Prevention Programs in Cardiac Patients with Multimorbidity: a Review by Nadezhda P. Lyamina, Galina K. Spirina, Oleg S. Glazachev

“…CONCLUSION. The data presented may recommend hypoxic conditioning technologies for wider implementation in cardiac rehabilitation programs for patients with multimorbid pathologies.…”
Get full text

Dynamic calculation of heat-flow coupled mine ventilation network with introduction of air volume fluctuation factor by Tong JIA, Heng MA, Ke GAO

“…The dynamic calculation for the fluctuating ventilation network facilitates precise quantitative mapping of the ventilation network state through real-time analysis of the coupling effect between the mine environment and ventilation variables, establishing a data foundation and optimized pathway for subsequent intelligent quantitative decision-making to enhance the adaptive adaptability and intrinsic precision of intelligent ventilation control.…”
Get full text

‘‘Practices and factors affecting on-site medical equipment maintenance at Wau Teaching Hospital, South Sudan’’ by Natale Massimino Ucin, Manassé Nimpagaritse, Shital Mahindra Maru, Mulatedzi Makhado, Shiferaw Mitiku Tebeka

“…An exploratory factor analysis was performed to test the inter-relationship between variables, Bartlett’s test of sphericity(p = 0,000) indicated a significant correlation, The Kaiser-Meyer- Olkin measure of sample adequacy was 0.800, and this value indicated the appropriateness of the data. …”
Get full text

Hepatoprotective Effect of Corm of Ensete ventricosum (Welw.) Cheesman Extract against Isoniazid and Rifampicin Induced Hepatotoxicity in Swiss Albino Mice by Abebe Dukessa Dubiwak, Tesaka Wondimnew Damtew, Mengistu Welde Senbetu, Delenasaw Yewhalaw, Tsegaye Girma Asere, Gebi Nemo, Minale Fekadie Baye

“…Data were entered into EpiData version 3.1 subsequently exported to SPSS version 25 for analysis by using one-way ANOVA. …”
Get full text

Clinical implications of intra-fraction CBCT image guidance in DIBH radiotherapy for left-sided breast cancer by BAO Zhengmin, LI Qianyong, LU Xiaoteng, YANG Yanju

“…Patients with satisfactory cardiopulmonary function and stable DIBH compliance were included. …”
Get full text

Real-time mobile broadband quality of service prediction using AI-driven customer-centric approach by Ayokunle A. Akinlabi, Folasade M. Dahunsi, Jide J. Popoola, Lawrence B. Okegbemi

“…The highlighted gap can be addressed by machine learning (ML), as it has been effectively used in the past to support the analysis and knowledge discovery of communication systems’ traffic data through identification of intricate and hidden patterns. …”
Get full text

Research on overburden movement laws and spontaneous combustion “three zones” of composite goaf in shallow buried depth and stereo-intersected coal seam group by Dianfu CHEN, Quan NI, Bing WU, Yang LI

“…Simulation results were validated using surface subsidence data, and the Fluent software was utilized to refine the delineation of the spontaneous combustion “three zones” in the composite goaf by incorporating an oxygen consumption function. …”
Get full text

Impact of Makarasana on Cardiovascular Parameters: A Prospective Interventional Study by Meenu Dahiya, Deepti Dwivedi, Nimarpreet Kaur, Pushpa Lamba, Sunil Chamola

“…Introduction: Makarasana, a yogic posture also known as the crocodile pose on elbows, is a gentle backbend practised in yoga for its potential physiological benefits, including enhanced breathing, digestive function and purported effects on spiritual and emotional wellbeing. …”
Get full text

Long‐Term Course of Depression After Stroke and Risk Factors for Symptoms With Poor Progression: A Population‐Based Study by Lu Liu, Iain J. Marshall, Ajay Bhalla, Xianqi Li, Salma Ayis, Charles D. A. Wolfe, Yanzhong Wang, Matthew D. L. O'Connell

“…Multinomial logistic regression examined associations between baseline factors, changes in function, and recurrent or persistent depression. Results The analysis comprised 1724 participants (mean age, 65.5 years; men, 55.9%, White race, 65.2%). …”
Get full text

Magnetic resonance imaging for noninvasive assessment of renal fat deposition and hypoxia in diabetic kidney disease by Jian Liu, Daoyu Yang, Chong Tian, Rui Lv, Rongpin Wang, Xianchun Zeng

Get full text