Disrupted functional connectome in a rodent model of autism during social isolation by Robert Gergely Kemecsei, Robert Gergely Kemecsei, Szizel Dániel-Papp, David Barnabas Balazs, Estifanos Ghebrihiwet Tewelde, Andras Csillag, Gergely Zachar

“…Control animals exhibited elevated c-Fos expression in the regions central to the mesolimbic reward system (MRS), social brain network (SBN), and stress-related networks, with the interpeduncular nucleus (IPN) at the core, compared to VPA-treated animals. Functional network analysis revealed a more widespread but less specific pattern of connectivity in VPA-treated animals. …”
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Association of physical function with masticatory ability and masticatory habits: a cohort study by Moeno Takeshita, Mariko Naito, Rumi Nishimura, Haruka Fukutani, Minami Kondo, Yuko Kurawaki, Sachiko Yamada, Noriyasu Uchibori

“…Abstract Background Few studies have evaluated masticatory ability and habits in relation to physical function. This study aimed to investigate the association of physical function with both masticatory ability and masticatory habits. …”
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Cognitive Rehabilitation Improves Functional Vision Skills in Children with Cerebral Visual Impairment by Zeynep Celik Turan, Esra Aki

“…<b>Results</b>: Statistically significant improvements were observed in GFVAI domains such as light sensitivity, distant visual field, focusing, maintaining focus, and obstacle avoidance (<i>p</i> < 0.05 to <i>p</i> < 0.01). Qualitative analysis also indicated a shift from low/moderate to good/very good performance in most functional vision categories. …”
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Host origin of microbiota drives functional recovery and Clostridioides difficile clearance in mice by Sophie A. Millard, Kimberly C. Vendrov, Vincent B. Young, Anna M. Seekatz

“…We found that a human-derived microbiota was less effective in clearing C. difficile compared to a mouse-derived microbiota, despite recovery of taxonomic diversity, compositional changes, and bacterial functions typically associated with clearance. Metabolomic analysis revealed deficits in secondary metabolites compared to those that received murine FMT, suggesting a functional remodeling between human microbes in their new host environment. …”
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Associations of depressive symptoms with lower extremity function and balance in Korean older adults by Bong Jo Kim, Kyupin Ha, Hyun Soo Kim, Hye Ran Bae, Minkook Son

“…Multivariable-adjusted logistic regression analysis was used to examine the association between depressive symptoms and lower extremity function and balance. …”
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THE SIGNIFICANCE OF FUNCTIONAL AND ETIOLOGICAL DIAGNOSTIC FOR TREATMENT STRATEGY DECISION IN PATIENTS WITH DILATED CARDIOMYOPATHY by Yu. V. Frolova

“…Conclusion. These data indicate that application of complex etiological and functional diagnostics allows us not only to make nosological diagnosis of patients with DCM but also to determine the type of treatment and prognosis.…”
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Structure and function of A41, a vaccinia virus chemokine binding protein. by Mohammad W Bahar, Julia C Kenyon, Mike M Putz, Nicola G A Abrescia, James E Pease, Emma L Wise, David I Stuart, Geoffrey L Smith, Jonathan M Grimes

“…The biological and structural data suggest that A41 functions by forming moderately strong (nM) interactions with certain chemokines, sufficient to interfere with chemokine-glycosaminoglycan interactions at the cell surface (microM-nM) and thereby to destroy the chemokine concentration gradient, but not strong enough to disrupt the (pM) chemokine-chemokine receptor interactions.…”
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

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Altered cerebellar activation patterns in Alzheimer’s disease: An activation likelihood estimation Meta-Analysis by Jessica A. Bernard, Ivan A. Herrejon, Emily An, Yamilet Cina, Sameera Dabbiru, Jack Dempsey, Elise Marrie, Michele Medina, Jessica Praytor

“…We took advantage of activation likelihood estimation (ALE) meta-analysis to investigate overlap in functional activation present in the existing literature. …”
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Research on Food Image Classification Algorithm based on Improved MobileNetV3-Large by HE Wei-chan, YANG Zhi-jing, QIN Jing-hui

“…Subsequently, a multi-task loss function was incorporated to further improve the classification performance by simultaneously optimizing multiple related tasks. …”
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Dynamic human liver proteome atlas reveals functional insights into disease pathways by Lili Niu, Philipp E Geyer, Rajat Gupta, Alberto Santos, Florian Meier, Sophia Doll, Nicolai J Wewer Albrechtsen, Sabine Klein, Cristina Ortiz, Frank E Uschner, Robert Schierwagen, Jonel Trebicka, Matthias Mann

“…Dramatic proteome changes in liver tissue include signatures of hepatic stellate cell activation resembling liver cirrhosis and providing functional insights. We built a web‐based dashboard application for the interactive exploration of our resource ( www.liverproteome.org ).…”
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Serotonin enhances neurogenesis biomarkers, hippocampal volumes, and cognitive functions in Alzheimer’s disease by Ali Azargoonjahromi, For the Alzheimer’s Disease Neuroimaging Initiative

“…Higher serotonin levels were linked to better cognitive function (negative correlation with CDR-SB, r = −0.230, p = 0.024). …”
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MAST Kinases’ Function and Regulation: Insights from Structural Modeling and Disease Mutations by Michael C. Lemke, Nithin R. Avala, Michael T. Rader, Stefan R. Hargett, Daniel S. Lank, Brandon D. Seltzer, Thurl E. Harris

“…<b>Methods</b>: We investigated MAST-lineage kinases using database and sequence analysis. We also estimate the functional consequences of disease point mutations on protein stability by integrating predictive algorithms and AlphaFold. …”
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Some Morpho-Functional Changes of the Left Heart in Patients with Viral Liver Cirrhosis by M V. Chistyakova, A. V. Govorin, N. N. Kushnarenko

“…All patients were evaluated diastolic function of the LV in accordance with the АSЕ/ЕAЕ-2009 and ASE/EACVI-2016 recommendations. …”
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“Holiday heart” syndrome in rats: Features of microcirculation, functional state and anatomy of the heart by S. A. Kryzhanovskii, I. B. Tsorin, E. O. Ionova, M. B. Vititnova, S. A. Simonenko, L. G. Kolik

“…In the remaining animals (n = 10), microcirculation of blood and lymph in the brain and heart was assessed on the 3rd day of alcohol deprivation.Results. Analysis of the obtained data showed that in the conditions of the “Holiday Heart” syndrome model, significant changes occur in the anatomy, functional activity and geometry of the heart: there is a significant thinning of the anterior wall of the left ventricle heart (LV), an increase in systolic and diastolic volumes and sizes of the LV and a significant (p = 0.0018) decrease in its inotropic function. …”
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The strong correlation between visual function improvement and retinal microcirculation enhancement in glaucoma by Ting Wang, Ting Wang, Qiying Ling, Boyu Shen, Xu Jia

“…We measured peripapillary and macular VD, retinal nerve fiber layer (RNFL) thickness, foveal avascular zone (FAZ), and visual field (VF) parameters before treatment, and at 1 week, 1 month, 3 months, and 6 months post-treatment. The data were analyzed using ANOVA and Pearson correlation analysis.ResultsA total of 20 patients were included. …”
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A functionally significant polymorphism in ID3 is associated with human coronary pathology. by Ani Manichaikul, Stephen S Rich, Heather Perry, Joseph Yeboah, Michelle Law, Molly Davis, Matthew Parker, Michael Ragosta, Jessica J Connelly, Coleen A McNamara, Angela M Taylor

“…In the current investigation, we characterize the association between the functionally significant polymorphism in ID3, rs11574, with human coronary pathology.…”
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Association of functional disability with cardiometabolic disease status in a national cohort study by Ping Ni, Fang Wang, Li Liu, Meiling Ge, Xiuying Hu

“…Generalized ordinal logistic regression analysis was employed to investigate the impact of functional disability on CMD status. …”
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Anatomic and Functional Varieties of Labial Frenum in Children During the Mixed Dentition Period by Farida S. Ayupova, Tatyana V. Gayvoronskaya, Sergey N. Alekseenko

“…To study the anatomical and functional varieties of labial frenum and their prevalence in children aged 6–11 years in the territories of the Krasnodar Krai.Materials and methods. …”
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Rules of acupoint and parameter selection for electrostimulation in treatment of functional dyspepsia based on bibliometrics by Dan WANG, Pei-jing RONG

“…Results: A total of 181 eligible articles were screened. Statistical analysis revealed that the most frequently targeted acupoints for electrostimulation in functional dyspepsia (FD) were Zusanli (ST36), Taichong (LR3), and Neiguan (PC6), while the most commonly utilized auricular point was Erjia (CO, concha zone). …”
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