Cerebrolysin: spectrum of activity and research data by N. D. Bukreeva, E. A. Rakityanskaya

Get full text

Real-World Effectiveness of Triple Extrafine Fixed-Dose Combination with Beclomethasone/Formoterol/Glycopyrronium on Symptoms and Lung Function in COPD: A Systematic Review and Met... by Rogliani P, Manzetti GM, Cazzola M, Calzetta L

“…Further research should explore long-term outcomes and investigate specific patient subgroups to optimize individualized treatment approaches.Keywords: COPD, symptoms, lung function, real-world evidence, meta-analysis…”
Get full text

Efficacy of Virtual Reality–Based Interventions on Cognitive Function in Patients With Neuropsychiatric Disorders: Systematic Review and Meta-Analysis of Randomized Controlled Tria... by Qiujing Du, Yuhan Wei, Yuexuan Ma, Changqing Liu, Shanshan Du, Qi Zhang, Xiaotong Gong, Jiaju Yang, Qijie Li, Ka Li

“…ObjectiveThis meta-analysis aims to evaluate the efficacy of VR-based interventions on cognitive function in patients with neuropsychiatric disorders by synthesizing data from randomized controlled trials (RCTs). …”
Get full text

Technological functionality and system architecture of mobile health interventions for diabetes management: a systematic review and meta-analysis of randomized controlled trials by Xinran Yu, Yifeng Wang, Zhengyang Liu, Euitay Jung

“…The quality assessment results indicated that most studies performed well in the completeness of outcome data and selective reporting.DiscussionThis meta-analysis confirms that mobile health applications with practical technological functionalities and system architectures are beneficial in managing diabetes. …”
Get full text

Cognitive functioning and work-related outcomes of non-central nervous system cancer survivors: protocol for a systematic review with meta-analysis by Sofia Fernandes, Ana F Oliveira, Juliana D Reis, Ana Torres, Isabel M Santos, Diane Von Ah

“…Two independent reviewers will assess studies for inclusion and extract data from each article using a standardised form. …”
Get full text

Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pte... by José Cristian Vidal-Quist, Félix Ortego, Bart N. Lambrecht, Stephane Rombauts, Pedro Hernández-Crespo

“…DEG data, combined with network clustering and functional enrichment analysis, highlighted distinct genes and biological processes for each stage and sex: females showed upregulation of genes related to cell division and oogenesis, with vitellogenins among the most abundant transcripts; males exhibited increased expression of genes encoding putative seminal fluid proteins (e.g. endopeptidases, serpins, antimicrobial peptides), and those involved in reproductive regulation (e.g. testis-specific serine kinases); while juveniles displayed enhanced expression of genes related to energy metabolism and growth. …”
Get full text

Changes in brain functional connectivity and clinical correlations in neuromyelitis optica spectrum disorder: a longitudinal resting-state fMRI study by Jiyuan Wang, Jing Huang, Xiong Kang, Huiqing Dong, Jie Lu

“…We identified resting-state networks (RSNs) using independent component analysis (ICA). Functional connectivity (FC) was analyzed both within RSNs and between region-of-interest seeds and whole-brain voxels. …”
Get full text

Impact of Warmed Irrigation Fluid During Shoulder Arthroscopy on Patient Temperature, Recovery, and Cognitive Function: A Prospective Analysis of Influencing Factors by Jingfeng Liu, Xiaohong Huang, Xiaowei Xu, Yanyan Song, Jie Chen, Pei Yu, Tingjun Ye, Yin Zhang, Dahang Zhao, Gen Li, Lei Wang, Ying Wang, Zhenjin Ju, Chengyu Zhuang

“…Results Analysis of the data from the 85 shoulder arthroscopy patients indicated that warming the irrigation fluid effectively prevented a decrease in core body temperature (nasopharyngeal and rectal temperatures), with significant differences observed at 120 min (nasopharyngeal temperature) and 105 min (rectal temperature). …”
Get full text

Disease-Resistance Functional Analysis and Screening of Interacting Proteins of ZmCpn60-3, a Chaperonin 60 Protein from Maize by Bo Su, Lixue Mao, Huiping Wu, Xinru Yu, Chongyu Bian, Shanshan Xie, Temoor Ahmed, Hubiao Jiang, Ting Ding

“…However, little is known about the function of maize chaperonin 60 protein. In the study, a gene encoding the chaperonin 60 proteins was cloned from the maize inbred line B73, and named <i>ZmCpn60-3</i>. …”
Get full text

Systemic S100A8/A9 in patients with moderate to severe acute ischemic stroke: Exploratory analysis of inflammation and functional outcome by Christoph Vollmuth, Felipe A. Montellano, Cornelia Fiessler, Fabian Essig, Christian Hametner, Alexander M. Kollikowski, Vivian Vogt, Mirko Pham, Peter U. Heuschmann, Karl Georg Haeusler, Guido Stoll, Hermann Neugebauer, Michael K. Schuhmann

Get full text

Rates of visual field change and functional progression in glaucoma following trabecular microbypass implantation of iStent technologies: a meta-analysis by Kevin Gillmann, Dana M Hornbeak

“…The aim of this meta-analysis is to determine the long-term effect of iStent technology implantation on glaucoma functional progression.Methods Electronic medical literature databases were searched to identify studies reporting on iStent technologies. …”
Get full text

Efficacy of respiratory muscle training in improving pulmonary function and survival in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis by María Jesús Benzo-Iglesias, Patricia Rocamora-Pérez, María de los Ángeles Valverde-Martínez, Amelia Victoria García-Luengo, Pedro Miguel Benzo-Iglesias, Remedios López-Liria

“…Design: A systematic review and meta-analysis of randomized controlled trials. Data sources and methods: Articles published in PubMed, PEDro, Scopus, and Web of Science databases up to July 2024. …”
Get full text

Multilevel and multidimensional features of socioeconomic status and cognitive function in older adulthood: a cross-sectional analysis of the IGNITE studyResearch in context by Jermon A. Drake, Lu Wan, Chaeryon Kang, Peter J. Gianaros, Patricio Solis-Urra, Haiqing Huang, Rebecca Reed, Charles H. Hillman, Eric D. Vidoni, Jeffrey M. Burns, Arthur F. Kramer, Edward McAuley, George Grove, Kirk I. Erickson, Lauren E. Oberlin

Get full text

Potential locations for non-invasive brain stimulation in treating ADHD: Results from a cross-dataset validation of functional connectivity analysis by Yue Yang, Sitong Yuan, Huize Lin, Yi Han, Binlong Zhang, Jinna Yu

“…Subsequently, functional connectivity (FC) analysis was performed using resting-state fMRI data from two independent databases comprising 116 patients with ADHD. …”
Get full text

Interval walking training as a potential contributor to motor function improvement in adults with type 2 diabetes mellitus: a retrospective analysis by Masanori Yamazaki, Manami Hosokawa, Kohei Kitajima, Mitsuhisa Komatsu

“…AimIn adults with type 2 diabetes mellitus (T2DM), hyperglycemia and related complications may impair skeletal muscle mass (SMM) and quality, leading to reduced motor function. This study aimed to evaluate the effects of interval walking training (IWT) on three motor function indicators: peak vertical ground reaction force normalized by body weight (F/w), rate of force development normalized by body weight (RFD/w), and balance index score (BIS).MethodsThis retrospective analysis utilized data from a previous pilot trial of IWT. …”
Get full text

Pathways between childhood trauma, clinical symptoms, and functioning in new-onset psychosis: novel insights from a network analysis approach by Dimitrios Kiakos, Luis Alameda, Ines Lepreux, Caroline Conchon, Livia Alerci, Marianna Gorgellino, Nadir Mebdouhi, Teya Petrova, Philippe Golay, Lilith Abrahamyan Empson, Philippe Conus, Sandra Vieira

“…Data from early assessments (2 and 6 months after admission) were used for analysis. …”
Get full text

Single versus double tendon transfer for improving shoulder function in brachial plexus birth palsy: a meta-analysis of comparative studies by Ahmed O. Sabry, Mohamed K. A. Genedy, Yara Kassem, Marwa El-Difrawy, Reem Shalata, Maziad Hennidi, Farah A. R. Salama, Badr Ali Mohammed Badr, Mohamed Abdel-Wahed

“…Conclusion In conclusion, our meta-analysis suggests that both single and double tendon transfers achieve comparable functional outcomes. …”
Get full text

Limited and inconclusive effects of computer-based neurocognitive training on PTSD, comorbid depression and executive functioning: a systematic review and meta-analysis by Patric Muschner, Lena Goldschmidt, Luisa Sophie Gröning, Gerd-Dieter Willmund, Martina Piefke

“…While computer-based neurocognitive training (c-bnt) has shown benefits in primary depression, its efficacy for PTSD remains unclear. This meta-analysis evaluated the impact of c-bnt on PTSD severity, comorbid depression, and neurocognitive functions. …”
Get full text

Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis by Meng Ren, Jingjing Xu, Wenjing Wang, Lexian Shen, Chaojie Wang, Haoyang Liu, Lu Chen, Chanjing Liu, Yongheng Tang, Jiening Wang, Tiantian Liu

“…ABSTRACT Background Non‐invasive brain stimulation (NIBS) has attracted significant attention as it has been proven to be effective in facilitating upper limb motor recovery in patients with stroke. This meta‐analysis evaluates the efficacy of dual‐site non‐invasive brain stimulation (DS‐NIBS) in improving upper extremity motor function after stroke. …”
Get full text

Analysis of the Clinical Efficacy of Interlock Detachable Coil Interventional Embolization on Pelvic Congestion Syndrome and Ovarian Reserve Function: A Retrospective Study by Wang P, Zheng XL, Wang YH, Tao Y, Wang WC

“…Moreover, the clinical efficacy and long-term changes in ovarian reserve functions were analyzed. For the comparison of measurement data before and after treatment within the group, paired - sample t - test was used for analysis. …”
Get full text