A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference. by Philippa M Beard, Samantha J Griffiths, Orland Gonzalez, Ismar R Haga, Tali Pechenick Jowers, Danielle K Reynolds, Jan Wildenhain, Hille Tekotte, Manfred Auer, Mike Tyers, Peter Ghazal, Ralf Zimmer, Jürgen Haas

“…In addition, functional and pathway analysis of the entire screen was carried out to highlight cellular mechanisms involved in VACV replication. …”
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Counterfactual explanations of tree based ensemble models for brain disease analysis with structure function coupling by Shaolong Wei, Zhen Gao, Hongcheng Yao, Xiaoyu Qi, Mingliang Wang, Jiashuang Huang

“…Specifically, we first construct SC and FC matrices from preprocessed diffusion-weighted DTI and resting-state functional fMRI data. Then, we quantify the SC-FC coupling strength of each region and convert it into feature vectors. …”
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Functional Diagnostic System for Multichannel Mine Lifting Machine Working in Factor Cluster Analysis Mode by Zimovets V. I., Shamatrin S. V., Olada D. E., Kalashnykova N. I.

“…In the article, information synthesis of FDS is performed within the framework of information-extreme intellectual data analysis technology, which is based on maximizing the information capacity of the system in the process of machine learning. …”
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Spatial, Functional, and Constructive Analysis of the Water Resource at the Archaeological Center of Tipon, Cusco, Peru, 2023 by Doris Esenarro, Jorge Lescano, Brenda Chalco, Nicole Tapia, Jesica Vilchez Cairo, Carlos Vargas Beltran, Cecilia Arriola, Rosa Ruiz Reyes

“…The methodology employed consists of a site study analysis, considering data on terrain, environment, climate, and water flow in the spatial, functional, and constructive aspects, supported by digital tools (Google Earth Pro 2024, AutoCAD 2024, SketchUP 2024, Sun Path 3D 2024, Photoshop 2024, and Twinmotion 2024). …”
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Acupuncture for post-cesarean pain and gastrointestinal function recovery: a meta-analysis and systematic review by Hejing Liu, Kehan Xing, Cai Liao, Jiapei Wang, Chenglin Tang, Siqin Huang

“…Data analysis was conducted using Stata 15.ResultA total of 26 studies involving 2,641 patients were included. …”
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Association between improved erectile function and dietary patterns: a systematic review and meta-analysis by Bin Yang, Chao Wei, Yu-Cong Zhang, De-Lin Ma, Jian Bai, Zhuo Liu, Xia-Ming Liu, Ji-Hong Liu, Xiao-Yi Yuan, Wei-Min Yao

“…The data compiled included author details; publication dates, countries, treatments, patient numbers, ages, follow-ups, and clinical trial outcomes, such as ED cases, odds ratios (ORs), confidence intervals (CIs), and International Index of Erectile Function-5 (IIEF-5) scores with means and standard deviations. …”
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Assessing the Clinical and Functional Status of COPD Patients Using Speech Analysis During and After Exacerbation by Mayr W, Triantafyllopoulos A, Batliner A, Schuller BW, Berghaus TM

“…CAT scores correlated with reading rhythm, and BORG scales with stability in articulation. Pulmonary function testing (PFT) correlated with speech pause rate and speech rhythm variability.Conclusion: Speech analysis may be a viable technology for classifying COPD status, opening up new opportunities for remote disease monitoring.Keywords: COPD, pathological speech, feature interpretation, personalization, digital health…”
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Analysis of risk factors related to thyroid function abnormality caused by programmed death-1 inhibitors by Lihong WANG, Huiyang SONG, Shufei ZANG, ling YE, Xuefei DANG

“…MethodsA retrospective analysis was conducted on the clinical data and biochemical indicators of 669 patients with malignant tumors who received PD-1 inhibitor therapy. …”
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Analysis of functional outcomes and complications of tibial bone defects treated with Ilizarov bone transport technique by Yaxin Zhang, Jidong Wang, Baoliang Jiao, Dongwei Feng, Zhaowei Li

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Surgical Management of Septic Arthritis of the Wrist: An Analysis of Short- and Long-Term Functional and Clinical Outcomes by Yonca Steubing, Felix Reinkemeier, Flemming Puscz, Sonja Verena Schmidt, Jannik Hinzmann, Marcus Lehnhardt, Mehran Dadras

“…Clinical outcomes were assessed through total active range of motion (TROM), grip strength, and patient-reported hand function using the DASH questionnaire. Data analysis examined correlations between comorbidities, surgical interventions and long-term outcomes. …”
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Imu-based kinematic analysis to enhance upper limb motor function assessment in neuromuscular diseases by Alessandra Favata, Roger Gallart-Agut, Luc van Noort, Jesica Exposito-Escudero, Julita Medina-Cantillo, Carme Torras, Daniel Natera-de Benito, Josep M. Font-Llagunes, Rosa Pàmies-Vilà

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Race, diabetes, and cognitive function: a cross-sectional analysis of intersecting disparities in the NHANES cohort by Lingling Wang, Qin Zhou, Yushuang Yin, Wenqi Zhang, Chen Wang, Guanwen Lin, Duozhi Wu, Zhihua Wang

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Functional immune profiling of hyper- and hypo-inflammatory subphenotypes of critical illness: a secondary analysis by E. Scott Halstead, E. Scott Halstead, E. Scott Halstead, Daniel J. McKeone, Daniel J. McKeone, Abigail M. Samuelsen, Shouhao Zhou, Anthony S. Bonavia, Anthony S. Bonavia, Anthony S. Bonavia

“…We recently investigated the association of organ dysfunction with ex vivo immune profiling in sixty (60) critically ill adult patients with sepsis. In this secondary analysis we measured cytokine biomarkers with an automated, microfluidic immunoassay device (Ella™) and sought to investigate the functional immune profiles of patients in the hyper/hypo-inflammatory subphenotype groups.MethodsSubjects were consecutively identified adults, older than 18 years, and enrolled within 48 hours of sepsis onset. …”
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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions by Kyle D. Gromer, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Colin Shearn, Swati Antala, Swati Antala, Joshua B. Wechsler, Carla M. Cuda, Cara L. Mack, Ronald J. Sokol, William J. Janssen, Richard M. Green, Harris Perlman, Deborah R. Winter, Sarah A. Taylor, Sarah A. Taylor

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Identification, Characterization, Expression Profiling and Functional Analysis of Tobacco <i>CalS</i> Gene Family by Hong Wang, He Meng, Xiaohan Qi, Yi Pan, Bailu Ji, Liuying Wen, Yanjun Zan, Huan Si, Yuanying Wang, Dan Liu, Aiguo Yang, Zhengwen Liu, Lirui Cheng

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Social Activity and Cognitive Functioning Over Time: A Coordinated Analysis of Four Longitudinal Studies by Cassandra L. Brown, Laura E. Gibbons, Robert F. Kennison, Annie Robitaille, Magnus Lindwall, Meghan B. Mitchell, Steven D. Shirk, Alireza Atri, Cynthia R. Cimino, Andreana Benitez, Stuart W. S. MacDonald, Elizabeth M. Zelinski, Sherry L. Willis, K. Warner Schaie, Boo Johansson, Roger A. Dixon, Dan M. Mungas, Scott M. Hofer, Andrea M. Piccinin

“…The current study sought to clarify the relationship between social activity and cognitive function over time using a coordinated data analysis approach across four longitudinal studies. …”
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The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis by Longyao Ma, Longyao Ma, Qiuying Tao, Qiuying Tao, Jinghan Dang, Jinghan Dang, Jieping Sun, Jieping Sun, Xiaoyu Niu, Xiaoyu Niu, Mengzhe Zhang, Mengzhe Zhang, Yimeng Kang, Yimeng Kang, Weijian Wang, Weijian Wang, Jingliang Cheng, Jingliang Cheng, Yong Zhang, Yong Zhang

“…Consequently, it is important to utilize relevant coordinate data for a comprehensive meta-analysis to identify the shared patterns of structural, functional, and multimodal alternations in TUD.MethodThe present study conducted a systematic retrieval of studies published on PubMed, Web of Science, and Scopus from January 1, 2010, to December 12, 2023, to identify studies on voxel-based morphometry (VBM) and resting-state functional magnetic resonance imaging (rs-fMRI) for TUD. …”
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A Comparison of Approaches for Segmenting the Reaching and Targeting Motion Primitives in Functional Upper Extremity Reaching Tasks by Kyle L. Jackson, Zoran Duric, Susannah M. Engdahl, Anthony C. Santago, Siddhartha Sikdar, Lynn H. Gerber

“…There is growing interest in the kinematic analysis of human functional upper extremity movement (FUEM) for applications such as health monitoring and rehabilitation. …”
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Machine learning-guided construction of an analytic kinetic energy functional for orbital free density functional theory by Sergei Manzhos, Johann Lüder, Pavlo Golub, Manabu Ihara

“…Machine learning (ML) of kinetic energy functionals (KEF) for orbital-free density functional theory (DFT) holds the promise of addressing an important bottleneck in large-scale ab initio materials modeling where sufficiently accurate analytic KEFs are lacking. …”
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Functional near⁃infrared spectroscopy of brain network functional connectivity in patients with post⁃stroke cognitive impairment by WANG Xinyu*，LIU Yanling，LIU Jiaqi，GAO Yunhan，JIN Yan，ZHU Chongtian

“…Objective To explore the similarities and differences of resting brain functional connectivity（FC）between patients with post-stroke cognitive impairment（PSCI）and healthy adults by functional near-infrared spectroscopy（fNIRS）.Methods A total of 40 PSCI patients hospitalized in the Rehabilitation Medicine Department of Linyi People’s Hospital from July 2023 to August 2024 and 20 healthy adults recruited from society were prospectively and randomly selected.fNIRS was used to detect the hemodynamic data of resting frontal lobe，parietal lobe and occipital lobe for 5 min in 20PSCI patients with left hemisphere stroke（LHS group），20 PSCI patients with right hemisphere stroke（RHS group）and20 healthy controls（control group）. …”
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