Effects of Internet Cognitive Behavioral Therapy for Insomnia and Internet Sleep Hygiene Education on Sleep Quality and Executive Function Among Medical Students in Malaysia: Proto... by Vijandran Mariappan, Firdaus Mukhtar

“…Data analysis will be performed by August 2025 and the research will be completed by December 2025. …”
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Assessment of Diastolic Function during the transitional period and infancy using Serial Echocardiography in a tertiary neonatal unit (DiFuSE): a longitudinal prospective observati... by Daragh Finn, Vicki Livingstone, Eugene Dempsey, Neidin Bussmann, Iyshwarya Stapleton

“…While a number of studies recently have assessed cardiac function in the newborn, there is a dearth of data on diastolic function in the neonatal period during transition and into infancy. …”
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Thermal Carbonization of Biomass Wood Dust and Algae Wastes via Microwave-Assisted H3PO4: Desirability Function and Statistical Optimization for Methylene Blue Dye Removal Authors by Raja Razuan Raja Deris, Hazierul F. Awang, Muhammad Hakim Azman, Intan Nur Hidayah Abdul Rashid, Ahmad Hapiz, Ruihong Wu, Abdallah Reghioua, Zaher Mundher Yaseen, Lee D. Wilson

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Using functional near-infrared spectroscopy to study effects of virtual reality intervention for adolescents with depression in a clinical setting in China: study protocol for a pr... by Yan Zhang, Lijun Wang, Dongsheng Zhou, Xiaofang Ye, Kunqiang Yu, Shaochang Wu, Shiqiao Lv, Linhui Liu, Xiuxiu Zheng, Ruomei Jin, Guoqing Min

“…This study first aims to evaluate the effectiveness of VR intervention on adolescent depression symptoms, and second, to determine the intervention’s underlying mechanism of effect using functional near-infrared spectroscopy (fNIRS).Methods and analysis This is a single-centre, prospective, randomised controlled clinical trial. …”
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Genome-Wide Identification of Heavy Metal ATPase Family in <i>Aegilops tauschii</i> and Functional Verification of <i>AetHMA4</i> and <i>AetHMA8</i> by Xiaolin Liang, Xiaofang Zhang, Yibo Li, Yifan Ding, Hongying Li, Ziyuan Hao, Ning Wang, Xiaojiao Han

“…This study provides experimental data regarding the function of the <i>AetHMA</i> gene in the transport, regulation, and detoxification of heavy metal elements in <i>A. tauschii</i>.…”
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Granulomatous lymphocytic interstitial lung disease in common variable immune deficiency: an in-depth clinical, immunological, functional and radiological exploration with a focus... by Mattia Moratti, Mattia Moratti, Gioacchino Schifino, Francesco Baccelli, Francesco Baccelli, Simona Ferrari, Elisabetta Magrini, Mirna Bassi, Aldo Guerrieri, Maurizio Zompatori, Marcello Lanari, Marcello Lanari, Francesca Conti, Francesca Conti

“…Current management strategies for GLILD rely on expert opinion due to a lack of randomized controlled trials (RCTs).ObjectivesThis study aims to provide a comprehensive immunophenotypical characterization of CVID patients with and without GLILD, investigate predictive biomarkers for GLILD development, and explore therapeutic strategies, particularly during concomitant SARS-CoV-2 and chronic cytomegalovirus (CMV) infections.SourcesPrimary data were collected from a cohort of 25 patients with CVID who underwent high-resolution computed tomography (HRCT), immunophenotyping, and serum immunoglobulin analysis at diagnosis and after immunoglobulin replacement therapy. …”
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Cognitive function and associations with demographic, socioeconomic, health and behavioural factors among older adult men and women in rural Bangladesh: a population-based cross-se... by Edward Fottrell, Harry Costello, Naveed Ahmed, Carina King, Sanjit Kumer Shaha, Tasmin Nahar, Malini Pires, Andrew Copas, Hassan Haghparast-Bidgoli, Joanna Morrison, Abdul Kuddus, Kishwar Azad

“…Empirical population-based studies of cognitive function and its association with demographic, socioeconomic, health and behavioural factors among older adults in low-resource setting are rare. …”
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Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids o... by Kayla A Boortz, Kristen E Syring, Lynley D Pound, Yingda Wang, James K Oeser, Richard M O'Brien

“…This study describes a functional analysis of 22 non-synonymous G6PC2 SNPs, that alter amino acids that are conserved in human G6PC1, mouse G6pc1 and mouse G6pc2, with the goal of identifying variants that potentially affect G6PC2 activity/expression. …”
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Chemoproteomic analysis of the pharmacological properties of vitamin В12 derivatives by I. Yu. Torshin, O. A. Gromova, I. A. Dereven’kov, L. A. Maiorova

“…Using the method of chemoinformational (chemoproteomic) analysis, implemented within the framework of algebraic recognition theory and topological data analysis, the constants of half-maximal inhibitory concentration (IC50) and half-maximal effective concentration (EC50) of human proteome proteins were assessed.Results. …”
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Real-world utilization of aromatase inhibitors, tamoxifen, and ovarian function suppression in premenopausal patients with early hormone receptor-positive, HER2-negative breast can... by Volkmar Müller, Manuel Hörner, Marc Thill, Maggie Banys-Paluchowski, Sabine Schmatloch, Peter A. Fasching, Nadia Harbeck, Dagmar Langanke, Sabrina Uhrig, Lothar Häberle, Dorothea Fischer, Alexander Hein, Tanja N. Fehm, Chloë Goossens, Jürgen Terhaag, Uwe Heilenkötter, Peter Dall, Christian Rudlowski, Rachel Wuerstlein, Mustafa Aydogdu, Mignon-Denise Keyver-Paik, Carolin Hammerle, Natalija Deuerling, Elmar Stickeler, Bahriye Aktas, Erik Belleville, Martin Thoma, Nina Ditsch, Yasmin Baila, Christian Roos, Christian Mann, Caterina Iuliano, Sara Y. Brucker, Andreas Schneeweiss, Andreas D. Hartkopf

“…Background: The optimal adjuvant endocrine treatment in premenopausal patients with hormone receptor-positive, HER2-negative (HRpos/HER2neg) early breast cancer (eBC) remains debated, particularly the choice between aromatase inhibitors plus ovarian function suppression (AI + OFS) or tamoxifen (TAM) with or without additional OFS. …”
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The topology of representational geometry by Shael Brown, Reza Farivar

“…This new method could be used in conjunction with regular RSA in order to make distinct, complementary inferences about neural function.…”
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STANet: A Novel Spatio-Temporal Aggregation Network for Depression Classification with Small and Unbalanced FMRI Data by Wei Zhang, Weiming Zeng, Hongyu Chen, Jie Liu, Hongjie Yan, Kaile Zhang, Ran Tao, Wai Ting Siok, Nizhuan Wang

“…STANet comprises the following steps: (1) Aggregate spatio-temporal information via independent component analysis (ICA). (2) Utilize multi-scale deep convolution to capture detailed features. (3) Balance data using the synthetic minority over-sampling technique (SMOTE) to generate new samples for minority classes. (4) Employ the attention-Fourier gate recurrent unit (AFGRU) classifier to capture long-term dependencies, with an adaptive weight assignment mechanism to enhance model generalization. …”
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Comparison of preference-based health-related quality of life measures for chronic neck pain: a pooled analysis of data from three RCTs by Eun-Jung Kim, In-Hyuk Ha, Yoon Jae Lee, Dongwoo Nam, Yeon Cheol Park, Seong Min Lee, Soo-Jin Kim

“…Objectives This study aimed to identify a preference-based health-related quality of life (HRQOL) measure that best reflects disease-specific features in patients with neck pain by comparing the characteristics of the instruments.Design Pooled data from three multicentre randomised controlled clinical trials (RCTs) on neck pain were included for analysis in this study.Setting All three RCTs were conducted between 2017 and 2020 in Korea, and patients were recruited from four hospitals and one university teaching hospital.Participants In total, 313 patients with neck pain were included in the three RCTs.Primary and secondary outcome measures A correlation analysis was conducted using Spearman’s correlation coefficients between preference-based HRQOL scores (EuroQol-5 Dimension 5 Levels (EQ-5D-5L) and Short-Form 6-Dimension version 1 (SF-6Dv1)) and the disease-specific measures for pain and function (Numerical Rating Scale (NRS), Visual Analogue Scale (VAS), Neck Disability Index (NDI) and Northwick Park Questionnaire).Results Spearman’s correlation analyses (p value &lt;0.01 for all) showed that EQ-5D-5L exhibited slightly stronger negative correlations with pain-related measures (VAS: −0.277, NRS: −0.262) compared with SF-6Dv1 (VAS: −0.207, NRS: −0.182). …”
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A Cost-Benefit Analysis of the Installation of an Automatic Incident Detection System in Vilnius by Aldona Jarašūnienė, Marta Novikova

“…A well-functioning transport network is a key element of a successful economy. …”
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Possible mechanisms of hypercholesterolemia and clinico-prognostic effects of lipid-lowering therapy in patients with coronary heart disease. (Literature review and original data a... by A. P. Vasilyev, N. N. Streltsova, M. A. Sekisova, Yu. N. Senatorov, I. A. Maltseva

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The Sensitivity Analysis of Whitecapping Dissipation Term for Calibration of SWAN Model Forced with ERA5 Winds in the Gulf of Oman by Amir Siahsarani, Majid Azadi, Behzad Layeghi, Davoud Babazadeh

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Identification of DCAF5 as a novel cancer prognostic and immunotherapy biomarker through pan-cancer analysis and renal clear cell carcinoma clinical data validation by Huaqing Yan, Liqi Zhang, Fan Xu, Tieding Chen, Rubing Li

“…This highlights its potential as a dual-functional biomarker for prognosis and immunotherapy personalization, particularly in SMARCB1-deficient malignancies.…”
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Electrolyte imbalance and liver function test abnormalities among pregnant women with hyperemesis gravidarum at Wag-himra zone public hospitals, Northeast Ethiopia, 2023: a compara... by Abebaw Worede, Teshiwal Deress, Habtamu Wondifraw, Getnet Fetene, Alemseged Berie

“…Blood samples were taken to determine liver function tests and electrolyte levels. Statistical analysis was performed using a one-way ANOVA with a Tuckey post hoc test, Kruskal-Wallis with a Mann–Whitney U test, and binary logistic regression analysis. …”
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The 4th Dimension in Animal Movement: The Effect of Temporal Resolution and Landscape Configuration in Habitat‐Selection Analyses by Johannes Signer, Cédric Scherer, Viktoriia Radchuk, Carolin Scholz, Florian Jeltsch, Stephanie Kramer‐Schadt

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Suppression of additive periodic low-frequency interference on eddy current defectograms by Leonid Y. Bystrov, Artemy N. Gladkov, Egor V. Kuzmin

“…Eddy current flaw detection is one of the popular methods of non-destructive rail testing. The data (defectograms) obtained from eddy current flaw detectors during rail testing are produced in large volume and therefore need in efficient automatic analysis. …”
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