Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms by Xu Cui, Houlin Ji, Shengyang Guo, Ju Liu, Linyuan Zhang, Yongwei Jia, Yin Cui, Xiaoxiao Zhou

“…ObjectiveTo construct a diagnostic model of osteoarthritis related to methylation genes using machine learning algorithms, and analyze its prognostic value and biological functions.MethodsThe GSE 63695 and GSE162484 datasets including human osteoarthritis (OA) and normal samples were downloaded from the GEO datasets. …”
Get full text

Ethnic differences in CKD progression among people with type 2 diabetes and rapid eGFR decline: A secondary data analysis by Thamer Alobaid, Matthew D. L. O’Connell, Janaka Karalliedde, Salma Ayis

Get full text

Association between overactive bladder and female sexual frequency: a cross-sectional analysis of the National Health and nutrition examination survey data by Bo Zhang, Yi Gu, Yuanyuan Li, Yiming Chen, Xingliang Feng

“…Results A total of 5590 women aged 20–59 were eligible in the final analysis from 2007 to 2016 NHANES. 30.43% of participants (n = 1701) were identified as FSD reporting sexual frequency of 0–11 times/year, while 69.57% of participants (n = 3889) were identified as normal female sexual function reporting sexual frequency > 11 times/year. …”
Get full text

Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…We asked all researchers to share the data they had originally collected with us and combined results using a network meta-analysis. …”
Get full text

Comparative analysis of the frequency of comorbid diseases in axial psoriatic arthritis and other variants of axial spondyloarthritis. Data from a hospital cohort by A. A. Yanushonite, Yu. L. Korsakova, T. V. Korotaeva, E. E. Gubar, E. Yu. Loginova, M. M. Urumova, A. E. Dimitreva, S. I. Glukhova

“…The Cumulative Illness Rating Scale (CIRS), Charlson comorbidity index (CCI) and the weighted version of Functional Comorbidity Index (w-FCI) were used to assess comorbidity.Results and discussion. …”
Get full text

Gait analysis and knee kinematics before surgery, 6 and 18 months after high tibial osteotomy by A. P. Prizov, N. V. Zagorodniy, A. M. Vostrikov, D. V. Skvortsov, G. A. Ayrapetov, F. L. Lazko, A. A. Akhpashev, A. V. Altukhova

Get full text

Prognostic significance of right ventricular dysfunction in heart failure with preserved ejection fraction: a meta-analysis of reconstructed time-to-event data by Roozbeh Narimani-Javid, Mehrdad Mahalleh, Kiyarash Behboodi, Kasra Izadpanahi, Alireza Arzhangzadeh, Reza Nikfar, Seyed Ali Hosseini, Ehsan Amini-Salehi, Sasan Shafiei, Hamed Vahidi, Kaveh Hosseini, Hamidreza Soleimani

“…RVD was defined as the deviation of at least one measurement of RV function from the recommended normal range based on modality and the normal ranges established in each study. …”
Get full text

Human brain single-cell data reveal shared synaptic dysfunction and immune abnormality in epilepsy and Alzheimer′s disease by YU Xiaolin, ZHANG Erning, SHA Longze

“…Methods The single-cell transcriptome sequencing data of brain tissue from AD and epilepsy patients were collected from gene expression omnibus (GEO) database followed by cell clustering, differential expression analysis and gene ontology (GO)functional enrichment analysis using R-based tools such as Seurat and cluster Profiler and video electroencephalogram (vEEG) monitoring and Western blot experiments. …”
Get full text

IoT-Driven Intelligent Curing of Face Slab Concrete in Rockfill Dams Based on Integrated Multi-Source Monitoring by Yihong Zhou, Yuanyuan Fang, Zhipeng Liang, Dongfeng Li, Chunju Zhao, Huawei Zhou, Fang Wang, Lei Lei, Rui Wang, Dehang Kong, Tianbai Pei, Luyao Zhou

“…This platform integrates essential functions such as two-way communication with gateway devices, data processing and analysis, system visualization, and intelligent curing control. …”
Get full text

MINN: A metabolic-informed neural network for integrating omics data into genome-scale metabolic modeling by Gabriele Tazza, Francesco Moro, Dario Ruggeri, Bas Teusink, László Vidács

“…The understanding of cellular behavior relies on the integration of metabolism and its regulation. Multi-omics data provide a detailed snapshot of the molecular processes underpinning cellular functions and their regulation, describing the current state of the cell. …”
Get full text

Time Series Forecasting for Air Quality with Structured and Unstructured Data Using Artificial Neural Networks by Kenneth Chan, Paul Matthews, Kamran Munir

Get full text

Comprehensive examination of resting state fMRI connectomics yields new insights into brain function deficits in Gulf War illness after accounting for heterogeneity in brain impair... by Guangming Yang, Robert W. Haley, Ying Guo, Kaundinya S. Gopinath

“…It does so by breaking down GWI into three main syndrome variants (GWS1, GWS2, and GWS3) based on factor analysis of symptoms presented by GWI veterans. Resting state fMRI (rsfMRI) is a uniquely useful brain imaging technique in that in a 10-min fMRI scan it can probe numerous brain function domains simultaneously. …”
Get full text

COMPUTATIONAL AND ANALYTICAL MODELS FOR EQUATIONS OF PARABOLIC TYPE WITH APPROXIMATE DATA ON THE BASIS OF METHODS OF APPLIED HARMONIC ANALYSIS AND VARIATIONAL METHOD OF WEIGHTED RE... by Igor Eduardovich Naats, Victoria Igorevna Naats, Roman Andreyevich Ryskalenko

“…It is assumed that the mathematical model requires attracting approximately given initial data or semiempirical functions for their determination. …”
Get full text

Features of Recruitment: Intelligent Text Analysis of Resume and Vacancies by Irina L. Sizova

“…It is found that the labor market functions under conditions of bounded rationality. …”
Get full text

Stability analysis and security control of nonlinear singular semi-Markov jump systems by Yang Song, Beiyan Yang, Jimin Wang

Get full text

COMPARISON OF GENERAL CLINICAL DATA FROM TWO INDEPENDENT REGISTERS AMONG MALE SUBJECTS IN ONE AREA TASHKENT CITY by G. A. Nagaeva, R. S. Mamutov

Get full text

Enhanced flux potential analysis links changes in enzyme expression to metabolic flux by Xuhang Li, Albertha J M Walhout, L Safak Yilmaz

“…Applied to human data, eFPA consistently predicts tissue metabolic function using either proteomic or transcriptomic data. …”
Get full text

Single Joint Hybrid Assistive Limb (HAL-SJ) robotic exoskeleton therapy in improving functional outcomes among workers with wrist fractures: Study protocol for a randomized control... by Eng Wah Tan, Siaw Chui Chai, Yoshiyuki Sankai, Masahiro Shingu, Nor Afifi Razaob, Hafez Hussain

“…<h4>Results</h4>Participants recruitment and data collection are in progress.<h4>Discussion</h4>Wrist fractures can produce some residual disability and pain that may impact the functionality of a person. …”
Get full text

Identification of spastic ataxia-related proteins via comparative proteomic analysis of the cerebellum of conditional Ankfy1 knockout mice by Rong Fu, Man Ding, Tong Yin, Linlin Zheng, Yue Liu, Hang Yu, Rumeng Zhou, Zuneng Lu

“…Enrichment analyses of these DEPs based on the Gene Ontology (GO), Orthologous Groups of Proteins (COG), and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases revealed functional clusters associated with neuronal cell morphogenesis, extracellular structures, regulation of Rho-GTPase, calcium signaling pathway, etc. …”
Get full text

The Trans-Urals in S.U. Remezov’s Atlases: Systematization of Settlement Patterns and Functional Purpose of Maps based on the Initial Development of the Tobol-Irtysh Region at the ... by Vladimir M. Kostomarov, Kirill Y. Krestyannikov, Vladislava O. Isaeva, Darya V. Kozlova

“…His world-renowned works are often used as sources for various studies of Siberia of the Petrine era; however, comparative analyses of geographical and source study potential are rarely conducted, as existing methods of source analysis generally rely on historical approaches. In our study we attempted to approach the typology and functional purpose of Remezov’s maps through the lens of analyzing geographical and historical data contained within them. …”
Get full text