GLN2 as a key biomarker and therapeutic target: evidence from a comprehensive pan-cancer study using molecular, functional, and bioinformatic analyses by Shuang Gao, Lei Zhang, Guoping Sun

“…Conclusion Comprehensive bioinformatics analysis of GNL2 in pan-cancer tissues, combined with experimental validation, elucidated the pan-cancer expression pattern of GNL2, determined its diagnostic and prognostic value, and explored the biological functions of GNL2. …”
Get full text

Association between creatinine clearance and mortality in Chinese patients with osteoporotic fractures: a retrospective cohort study by Ming Su, Ming Su, Peng Zhou, Peng Zhou, Min-zhe Xu, Min-zhe Xu, Ya-qin Gong, Ya-qin Gong, Jian Jin, Wen-bin Hu, Ke Lu, Ke Lu, Chong Li, Chong Li, Yi Yin, Yi Yin

“…BackgroundCreatinine clearance (CCR) is a vital biomarker for evaluating renal function, indicating the efficiency of the kidneys in filtering blood waste. …”
Get full text

SOX11 and GLIS2: Novel Biomarkers for Understanding the Progression of Oral Leukoplakia by Yi Li, Zhencun Tang, Chenliang Xiao, Jun Su, Lijia He, Wenyun Zhang

Get full text

Optimasi Algoritma Support Vector Machine Berbasis Kernel Radial Basis Function (RBF) Menggunakan Metode Particle Swarm Optimization Untuk Analisis Sentimen by Cucun Very Angkoso, Khozainul Asror, Ari Kusumaningsih, Andi Kurniawan Nugroho

“…Penelitian ini bertujuan mengevaluasi efektivitas algoritma Particle Swarm Optimization (PSO) dalam meningkatkan akurasi analisis sentimen pada algoritma Support Vector Machine (SVM) dengan kernel Radial Basis Function (RBF). Data ulasan dikumpulkan melalui web scraping dari komentar di Google Play untuk tiga aplikasi Fintech, yaitu Flip, Neobank, dan Bank Jago. …”
Get full text

Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers by Aketilieke Nusufujiang, Mulalibieke Heizhati, Nanfang Li, Ling Yao, Wenbo Yang, Hui Wang, Mei Li, Lin Gan, Adalaiti Maitituersun, Miaomiao Liu, Qiaolifanayi Nuermaimaiti, Li Cai, Xiayire Aierken, Xiufang Li, Qin Luo, Jing Hong

“…BackgroundAldosterone is the effector hormone in the renin angiotensin aldosterone system and existing data suggest aldosterone affect cognitive function. …”
Get full text

Assessing urban spatial vitality in post-port areas: a multimodal data analysis of Shanghai, Liverpool, and Marseille by Chen Zeng, Tianchen DAI, Feng Wang, Jiangyue Wu

Get full text

Testicular appendix (hydatid of Morgagni) torsion in adult urological management: evaluation of treatment outcomes by I. S. Shormanov, D. N. Shedrov, D. Y. Garova, A. I. Ryzhkov

“…Scrotal ultrasound (US) and Doppler US of testicular vessels were compared, endocrine status (levels of total testosterone, luteinising hormone, follicle-stimulating hormone) and reproductive function were studied based on the results of semen analysis and MAR-test.Results. …”
Get full text

The First Saint Petersburg Regional Inflammatory Bowel Diseases Registry on the Basis of the Regional Health Information System: Principles of Functioning, Testing Results, Plan of... by Yu. P. Uspenskiy, A. M. Sarana, L. N. Melentyeva, A. V. Yazenok, S. V. Petrov, Yu. A. Fominykh, S. V. Ivanov, A. V. Shotik, A. M. Segal, T. V. Gorbacheva, S. D. Plotnikova, K. V. Dronov

“…Saint Petersburg IBD Registry operates on the basis of the Saint Petersburg Medical Center of Information and Analysis within the framework of the Regional Medical Data Collection System of the Russian state information system “Regional Fragment of the Unified State Information System in the Healthcare Branch”. …”
Get full text

SpecDis: Value Added Distance Catalog for 4 Million Stars from DESI Year-1 Data by Songting Li, Wenting Wang, Sergey E. Koposov, Ting S. Li, Youjia Wu, Monica Valluri, Joan Najita, Carlos Allende Prieto, Amanda Byström, Christopher J. Manser, Jiaxin Han, Carles G. Palau, Hao Yang, Andrew P. Cooper, Namitha Kizhuprakkat, Alexander H. Riley, Leandro Beraldo e Silva, Jessica Nicole Aguilar, Steven Ahlen, David Bianchi, David Brooks, Todd Claybaugh, Axel de la Macorra, John Della Costa, Arjun Dey, Peter Doel, Jaime E. Forero-Romero, Enrique Gaztañaga, Satya Gontcho A Gontcho, Gaston Gutierrez, Klaus Honscheid, Mustapha Ishak, Stephanie Juneau, Robert Kehoe, Theodore Kisner, Anthony Kremin, Martin Landriau, Laurent Le Guillou, Michael Levi, Marc Manera, Aaron Meisner, Ramon Miquel, John Moustakas, Nathalie Palanque-Delabrouille, Will Percival, Claire Poppett, Francisco Prada, Ignasi Pérez-Ràfols, Graziano Rossi, Eusebio Sanchez, David Schlegel, Michael Schubnell, Hee-Jong Seo, Joseph Harry Silber, David Sprayberry, Gregory Tarlé, Benjamin Alan Weaver, Rongpu Zhou, Hu Zou

“…To build up an unbiased training sample, we do not apply selections on parallax error or signal-to-noise (S/N) of the stellar spectra, and instead, we incorporate parallax error into the loss function. Moreover, we employ principal component analysis to reduce the noise and dimensionality of stellar spectra. …”
Get full text

Expression and clinical significance of FANCI gene in pan-cancer: a comprehensive analysis based on multi-omics data by Yunzheng Zhao, Yunzheng Zhao, Qingyu Li, Qingyu Li, Jiajun Li, Jiajun Li, YiFeng Cui, YiFeng Cui, Zhaoyang Lu, Zhaoyang Lu

“…This investigation seeks to clarify the expression profiles, prognostic relevance, and diagnostic capabilities of FANCI across multiple malignancies, along with its links to immune cell infiltration, genetic alterations, protein-protein interactions, and functional roles.MethodsBy utilizing data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases, we conducted a comprehensive analysis of FANCI mRNA expression using R software and visualized the results with the ggplot2 package. …”
Get full text

Post-Coronavirus Disease 2019 (COVID-19) Liver Injury in Pregnant Women: A Retrospective Cohort Study by Yannan Gu, Ying Xing, Jing Zhu, Li Zeng, Xiaohong Hu

“…This study aimed to describe the incidence of abnormal liver function tests (LFTs) in post-COVID-19 pregnant women, and to explore characteristics of pregnant women with abnormal LFTs. …”
Get full text

Multimodal Classification of Alzheimer’s Disease Using Longitudinal Data Analysis and Hypergraph Regularized Multi-Task Feature Selection by Shuaiqun Wang, Huan Zhang, Wei Kong

“…Alzheimer’s disease, an irreversible neurodegenerative disorder, manifests through the progressive deterioration of memory and cognitive functions. While magnetic resonance imaging has become an indispensable neuroimaging modality for Alzheimer’s disease diagnosis and monitoring, current diagnostic paradigms predominantly rely on single-time-point data analysis, neglecting the inherent longitudinal nature of neuroimaging applications. …”
Get full text

Orofacial functions with emphasis on breathing and chewing patterns in individuals with and without molar incisor hypomineralisation: observational study protocol conducted in a de... by Ana Paula Taboada Sobral, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori, Amanda Rafaelly Honório Mandetta, Cinthya Cosme Gutierrez Duran, Caroline Diniz Pagani Vieira Ribeiro, Fabiana Car Pernomiam, Caroline Cristina Batista Camargo, Iara Maria Freitas Romano

“…For normally distributed data, analysis of variance and Tukey’s post hoc test will be used. …”
Get full text

Effectiveness of predictive scoring systems in predicting mortality in relation to baseline kidney function in adult intensive care unit patients: a systematic review protocol by Greg Knoll, Ayub Akbari, Risa Shorr, Edward G Clark, Gregory L Hundemer, Amos Buh, Hajar El Wadia, Abdulghani Omar Kabli, Marisha Karim, Nandini Biyani, Inok Lee

“…All data that will be included in the analysis will be publicly available and will be included in the final manuscript. …”
Get full text

Changes in the labor market with the introduction of scientific and technological innovations into the economy (foreign and domestic experience) by V. V. Erokhin

Get full text

Effects of external Chinese herbal therapy combined with pulse electromagnetic field on older adults with knee osteoarthritis: study protocol for a randomized controlled trial by Xiang Li, Foxiao Li, An Yu, Qi Bu, Ruirui Wang, Lijing Li, Wei Zhang, Lei Yang

“…The study findings will not only inform clinical practice by offering data-driven recommendations but also enrich the scientific discourse on the complex interplay between inflammation, pain, and function in KOA.Clinical trial registrationChinese clinical trial registry platform: www.chictr.org.cn (no. …”
Get full text

Effect of gadopentetate dimeglumine on T1 signal intensity in dentate nucleus from patients with mild renal dysfunction by SONG Li, SHEN Ya-qi, MA Li-ya, LI Zhen, HU Dao-yu, ZHANG Jing, XU Chu-ou

“…Methods Retrospective analysis was performed on 59 cases of clinical and imaging data from three or more MR enhanced scans in our hospital, measuring the average signal intensity of right dentate nucleus and right frontal white matter. …”
Get full text

Prognostic value of the Naples Prognostic Score in adult chronic obstructive pulmonary disease: NHANES 2005–2018 by Yue Kang, Yue Kang, Yingjian Tan, Yongxin Tie, Yujing Zhang, Chenyu Cui, Yuanyuan Zhao

“…We used weighted logistic regression to assess whether the NPS and COPD had a relationship, as well as its association with lung function. Subgroup analysis was used to detect the interaction. …”
Get full text

Ensemble learning techniques reveals multidimensional EEG feature alterations in pediatric schizophrenia by Ying Mao, Ying Mao, Fang Wang, Shan Wang, Zhaowei Wang, Gang Li, Xuchen Qi, Xuchen Qi, Yu Sun, Yu Sun

“…Schizophrenia (SCZ) is a severe mental disorder that impairs brain function and daily life, while its early and objective diagnosis remains a major clinical challenge due to the reliance on subjective assessments. …”
Get full text

A MODELING OF A DAMPING OF THE SLOW MAGNETOACOUSTIC WAVES IN A HIGHTEMPERATURE PLASMA by S. B. Derteev, G. A. Mankaeva, M. E. Sapraliev, A. K. Baltykov, D. B. Bembitov

“…Linear analysis still uses a simplified local representation of the plasma radiative loss function as a degree of temperature [1], which, in our opinion, leads to large errors in the results. …”
Get full text