Selectivity towards methyl mercaptan of Pt-PtO functionalized WO3 nanostructures made by flame spray pyrolysis by Kanittha Inyawilert, Matawee Punginsang, Chonlada Dechakiatkrai Theerakarunwong, Anurat Wisitsoraat, Chaikarn Liewhiran

“…This work presented 0–1 wt% Pt-PtO functionalized WO3 nanostructures synthesized by flame spray pyrolysis (FSP) for methyl mercaptan (CH3SH)-sensing applications. …”
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Defining the functional domain of programmed cell death 10 through its interactions with phosphatidylinositol-3,4,5-trisphosphate. by Christopher F Dibble, Jeremy A Horst, Michael H Malone, Kun Park, Brenda Temple, Holly Cheeseman, Justin R Barbaro, Gary L Johnson, Sompop Bencharit

“…Combining computational modeling and biological data, we propose that the CCM protein complex functions in the PI3K signaling pathway through the interaction between PDCD10 and PtdIns(3,4,5)P3.…”
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MiRNAs differentially expressed in vegetative and reproductive organs of Marchantia polymorpha – insights into their expression pattern, gene structures and function by Bharti Aggarwal, Wojciech Maciej Karlowski, Przemyslaw Nuc, Artur Jarmolowski, Zofia Szweykowska-Kulinska, Halina Pietrykowska

“…In the case of one miRNA precursor, we provide evidence that it encodes two functional miRNAs with two independent targets. Overall, our research sheds light on liverwort-specific miRNA gene structure, provides new data on their biogenesis and expression regulation. …”
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Comparison of Left Ventricular Function after His Bundle Pacing vs Left Bundle Branch Area Pacing Implantation by Kurniawan Prakoso, Kevin Wibawa, Giky Karwiky, Mohammad Rizki Akbar, Januar Wibawa Martha, Mohammad Iqbal

“… Background: Right ventricular pacing may lead to deterioration of left ventricular (LV) function. Recent guideline suggests the use of conduction system pacing (CSP) with either his bundle pacing (HBP) or left bundle branch area pacing (LBBAP). …”
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Association of a PAI-1 Gene Polymorphism and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function. by Seong H Cho, Jin-Young Min, Dong Young Kim, Sam S Oh, Dara R Torgerson, Maria Pino-Yanes, Donglei Hu, Saunak Sen, Scott Huntsman, Celeste Eng, Harold J Farber, William Rodriguez-Cintron, Jose R Rodriguez-Santana, Denise Serebrisky, Shannon M Thyne, Luisa N Borrell, L Keoki Williams, William DuPont, Max A Seibold, Esteban G Burchard, Pedro C Avila, Rajesh Kumar

“…<h4>Methods</h4>We included Latino children, adolescents, and young adults aged 8-21 years (1736 subjects with physician-diagnosed asthma and 1747 healthy controls) from five U.S. centers and Puerto Rico after excluding subjects with incomplete clinical or genetic data. We evaluated the independent and joint effects of a PAI-1 gain of function polymorphism and bronchiolitis / Respiratory Syncytial Virus (RSV) or other lower respiratory infections (LRI) within the first 2 years of life on asthma risk, asthma exacerbations and lung function.…”
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How Do Occupational Sedentary Behavior and Occupational Cognitive Complexity Relate to Cognitive Function? A Cross‐Sectional Study by Nabeela Rizvi, Honghuang Lin, Alexa S. Beiser, Nicole L. Spartano

“…Analysis of covariance (ANCOVA) models were used to evaluate the association of occupational sedentary time (independent variable) with cognitive function (dependent variable), including models adjusting for age, sex, leisure time physical activity (LTPA), education, and OCC. …”
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Long-term outcomes after a radioactive iodine treatment for a single autonomous functioning thyroid nodule in Japan by Ai Yoshihara, Jaeduk Yoshimura Noh, Kosuke Inoue, Masakazu Koshibu, Rei Hirose, Masahiro Ichikawa, Nami Suzuki, Masako Matsumoto, Miho Fukushita, Natsuko Watanabe, Kiminori Sugino, Koichi Ito

“…This study provided long-term outcome data regarding nodule volume change and thyroid function in AFTN patients following single fixed-dose RAIT, and it identified risk factors for nodule enlargement and persistent hyperthyroidism after RAIT. …”
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A novel peptide inhibitor of TRPM2 channels improves recovery of memory function following traumatic brain injury by James E. Orfila, Robert M. Dietz, Christian Schroeder, Olivia P. Patsos, Amelia Burch, Kiara E. Bahamonde, Kelley A. Coakley, Danelle J. Carter, Amy C. Clevenger, Tara B. Hendry-Hofer, Tuan D. Le, Joseph K. Maddry, Joseph K. Maddry, Joseph K. Maddry, Steven G. Schauer, Steven G. Schauer, Steven G. Schauer, Vikhyat S. Bebarta, Paco S. Herson

“…However, mice treated with tat-M2NX after TBI exhibited preserved LTP, consistent with the improved memory function observed in our behavioral studies. While this data implicates TRPM2 in brain pathology following TBI, the improvement in memory function without providing histological protection suggests that administration of tatM2NX at an acute time point differentially affects hippocampal regions compared to cortical regions.…”
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Unveiling the Microbial Signatures of Arabica Coffee Cherries: Insights into Ripeness Specific Diversity, Functional Traits, and Implications for Quality and Safety by Gabriela N. Tenea, Victor Cifuentes, Pamela Reyes, Marcelo Cevallos-Vallejos

“…Metagenomic sequencing generated over 416 million high-quality reads, averaging 66 million clean reads per sample and yielding a total of 47 Gbps of data. Analysis revealed distinct differences in species abundance based on the coffee variety and ripening stage. …”
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PRINCIPAL COMPONENT ANALYSIS-VECTOR AUTOREGRESSIVE INTEGRATED (PCA-VARI) MODEL USING DATA MINING APPROACH TO CLIMATE DATA IN THE WEST JAVA REGION by Devi Munandar, Budi Nurani Ruchjana, Atje Setiawan Abdullah

“…The Knowledge Discovery in Database (KDD) method was conducted for empirical analysis. Pre-processing is an analysis of raw climate data. …”
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A Density Functional Theory-Based Particle Swarm Optimization Investigation of Metal Sulfide Phases for Ni-Based Catalysts by Houyu Zhu, Xiaohan Li, Xiaoxin Zhang, Yucheng Fan, Xin Wang, Dongyuan Liu, Zhennan Liu, Xiaoxiao Gong, Wenyue Guo, Hao Ren

“…Under typical reactive adsorption desulfurization conditions, the ab initio thermodynamics analysis indicates that Ni₃S₂ is the most stable sulfide phase, consistent with sulfur K-edge XANES data. …”
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The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells by Shuhd Bin Eshaq, Jalal Taneera, Shabana Anjum, Abdul Khader Mohammed, Mohammad H. Semreen, Karem H. Alzoubi, Mohamed Eladl, Yasser Bustanji, Eman Abu-Gharbieh, Waseem El-Huneidi

“…RNA-seq data analysis confirmed the expression of AHR in human islets, with elevated levels observed in pancreatic islets obtained from diabetic and obese donors compared to non-diabetic or lean donors. …”
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Structural and functional alterations of the hippocampal subfields in T2DM with mild cognitive impairment and insulin resistance: A prospective study by Chen Yang, Huiyan Zhang, Zihan Ma, Yanjun Fan, Yanan Xu, Jian Tan, Jing Tian, Jiancang Cao, Wenwen Zhang, Gang Huang, Lianping Zhao

“…Method A total of 104 T2DM patients were recruited in this prospective study and divided into four groups (T2DM‐MCI‐higherIR, n = 17; T2DM‐MCI‐lowerIR, n = 32; T2DM‐nonMCI‐higherIR, n = 19; T2DM‐nonMCI‐lowerIR, n = 36). Structure and function MRI data were captured. Clinical variables and neuropsychological scores were determined for all participants. …”
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Dynamics of Structural and Functional Changes of Patients with Dry Form Age-related Macular Degeneration after Double Filtration Plasmapheresis by A. A. Volozhev, A. N. Kulikov, A. N. Belskih, D. S. Maltsev, S. E. Bednova, E. N. Nikolaenko

“…To study along with data of OCT, OCT angiography, visometry, microperimetry and electroretinography structural and functional changes in the macular zone in patients with a dry form of age-related macular degeneration after the using of double filtration plasmapheresis.Patients and methods. …”
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Exploring the association between hemoglobin glycation index and cognitive function in older adults with hypertension: a cross-sectional study by Hong Ding, Tingyue Kang, Wenbo Gao, Qi Wang, Shu Liu, Xiaowei Zhang, Jing Yu

“…According to the results from RCS analysis, HGI presented a linear relevance to cognitive function scores in older adults with hypertension. …”
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First trimester thyroid function in pregnant women residing in Saint Petersburg (Russia): reference values and risk of gestational diabetes by Polina V. Popova, Ekaterina S. Shilova, Alexandra S. Tkachuk, Alexandra V. Dronova, Anna D. Anopova, Alla E. Nikolaeva, Elena N. Grineva

“…The association between thyroid function, thyroid autoimmunity and the risk of GDM we estimated. …”
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The landscape in the gut microbiome of long-lived families reveals new insights on longevity and aging – relevant neural and immune function by Jingjing Wang, Jinlong Qie, Danrong Zhu, Xuemei Zhang, Qingqing Zhang, Yuyu Xu, Yipeng Wang, Kai Mi, Yang Pei, Yang Liu, Guozhong Ji, Xingyin Liu

“…Impressively, the associated analysis for gut microbiota with the level of Aβ, BDNF, and inflammatory factors suggests Bifidobacterium pseudocatenulatum could be a particularly beneficial bacteria in the improvement of impaired neural and immune function. …”
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Effects of ginger supplementation in individuals with mild to moderate joint pain I: ratings of pain, functional capacity, and markers of inflammation by Jacob Broeckel, Landry Estes, Megan Leonard, Broderick Dickerson, Drew E. Gonzalez, Martin Purpura, Ralf Jäger, Ryan Sowinski, Christopher J. Rasmussen, Richard B. Kreider

“…Participants were matched by age, sex, and body mass for double-blind and to ingest 125 mg/d of a placebo or ginger (GingerT3®, Specnova LLC, Tysons Corner, Virginia), standardized to contain 10% total gingerols and no more than 3% total shogaols) for 58 days. Data were analyzed using the general linear model (GLM) analysis of variance with repeated measures, mean changes from baseline with 95% confidence intervals, and chi-squared analysis.Results There was evidence that ginger supplementation: 1.) attenuated perceptions of muscle pain in the vastus medialis (Day 2: χ2 p = 0.087); 2.) reported less pain from sitting (Day 2: χ2 p = 0.02), while nocturnal pain (Day 32: χ2 p = 0.075, Day 58: (χ2 p = 0.097), weight bearing pain (Day 32: χ2 p = 0.058), physical functioning of performing heavy duties (Day 32: χ2 p = 0.100), and physical functioning of performing light duties (Day 2: χ2 p = 0.064) on WOMAC questions; 3.) experienced significant reductions in WOMAC overall ratings of pain, stiffness, physical function, and total score values, particularly in 48-hour follow-up measures; 4.) reported less pain during nighttime bed rest (Day 2: χ2 p = 0.065; Day 32: χ2 p = 0.032) and when going up and down stairs (Day 32: χ2 p = 0.097) from the LEQ; and, 5.) promoted significant differences over time and/or between groups in IL-β, IL-5, IL-6, IL-8, INF-γ, TNF-α, and high sensitivity C-reactive Protein at various points during the study.Conclusion Ginger supplementation promotes some favorable effects on exercise-induced perceptions of pain, functional capacity, and inflammatory markers in men and women who have mild to moderate muscle and joint pain.Registered clinical trial #ISRCTN74292348.…”
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The Experience of Observational Departments’ Functioning for Treatment of Patients with Tuberculosis from COVID-19 Contact and Convalescents after COVID-19 by E. M. Bogorodskaya, E. A. Kotova, E. L. Khristoforova, I. V. Nozdrevatykh

“…Results and discussion. The evaluation data on functioning efficacy of observational departments for patients with tuberculosis from COVID-19 contact and convalescent patients with tuberculosis after COVID-19 within the large medical institution hospital of physiatry profile. …”
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Targeting CD96 overcomes PD-1 blockade resistance by enhancing CD8+ TIL function in cervical cancer by Meng Zhang, Guiling Li, Jing Peng, Keqin Hua, Yumeng Wang, Congwen Wang, Junjun Qiu, Xinyu Qu, Chong Lu, Mingxing Zhang, Xingling Qi

“…Treatment with the CD96 blockade significantly enhanced the PD-1 blockade to blunt tumor growth and improve the function of CD8+ TILs in both mouse and CC specimen models.Conclusions Our findings showed that CD96 and PD-1 cooperatively and negatively regulate the function of CD8+ TILs, and CD96 blockade has promise for use in combination with PD-1 blockade for the treatment of CC.…”
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