Functional circuits of LYL1 controlled by supraphysiological androgen in prostate cancer cells to regulate cell senescence by Mehdi Heidari Horestani, Katrin Schindler, Aria Baniahmad

“…Regulatory feedback loops were identified by rescue experiments. Functional analysis revealed that KD of BHLHE40 reduces whereas LYL1 KD enhances p27kip1 levels. …”
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Evaluation of the polymorphism of the GDF9 and BMP15 genes and their relationship with the reproductive functions of sheep of different breeds by Z. K. Gadzhiev, E. S. Surzhikova, D. D. Evlagina, A. I. Surov, S. N. Shumaenko

“…The genetic structure of genes has been studied by methods of genetic and statistical analysis of the data obtained.Conclusion. The genetic structure of sheep populations of different breeds bred in the foothills of the Republic of Dagestan and the arid region of Stavropol Territory was studied for the first time. …”
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Altered Small-World Networks in First-Episode Schizophrenia Patients during Cool Executive Function Task by Zongya Zhao, Yaqing Cheng, Zhenxin Li, Yi Yu

“…Brain functional connectivity between all pairs of EEG channels was constructed based on mutual information (MI) analysis. …”
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Clinical and Functional Characterization of Novel AGL Variants in Two Families with Glycogen Storage Disease Type III by Tingting Yu, Hao Fu, Aoyu Yang, Yan Liang

“…The pathogenicity of the novel variants was furthermore assessed through bioinformatics analysis and cellular functional validation experiments. …”
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TNF signaling mediates cellular immune function and promotes malaria parasite killing in the mosquito Anopheles gambiae. by George-Rafael Samantsidis, Hyeogsun Kwon, Megan Wendland, Catherine Fonder, Ryan C Smith

“…Through gene expression analysis, RNAi, and in vivo injection of recombinant TNF-α, we provide direct evidence for the requirement of TNF signaling in regulating mosquito immune cell function by promoting granulocyte midgut attachment, increased granulocyte abundance, and oenocytoid rupture. …”
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Validation of skeletal muscle cis-regulatory module predictions reveals nucleotide composition bias in functional enhancers. by Andrew T Kwon, Alice Yi Chou, David J Arenillas, Wyeth W Wasserman

“…Comparison with recent MyoD and histone modification ChIP-Seq data supports the validity of the functional regions.…”
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Perfusion Deficits and Functional Connectivity Alterations in Memory-Related Regions of Patients with Post-Traumatic Stress Disorder. by Yang Liu, Baojuan Li, Na Feng, Huangsheng Pu, Xi Zhang, Hongbing Lu, Hong Yin

“…By using altered CBF regions as regions-of-interest, seed-based functional connectivity analysis was then performed. …”
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The Ability of AST-120 to Lower the Serum Indoxyl Sulfate Level Improves Renal Outcomes and the Lipid Profile in Diabetic and Nondiabetic Animal Models of Chronic Kidney Disease: A... by Hande O. Altunkaynak, Eda Karaismailoglu, Ziad A. Massy

“…However, it is not known whether AST-120 influences lipid abnormalities as well as renal function in patients with CKD and diabetes. The objective of the present meta-analysis was to evaluate the efficacy of AST-120 treatment in CKD using data from preclinical studies. …”
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Syntactic Complexity and Communicative Moves of Applied Linguistics Research Article Abstracts: A Function first Approach by Rajab Esfandiari, Mohammad Ahmadi, Aynur Ismayilli Karakoç

“…SPSS (version 25) was run for the analysis of data. Results of one-way MANOVA (multivariate analysis of variance) and Chi-square tests revealed significant variations among rhetorical moves in terms of clausal and phrasal complexity measures. …”
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Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy. by Rita Mendes de Almeida, Joana Tavares, Sandra Martins, Teresa Carvalho, Francisco J Enguita, Dulce Brito, Maria Carmo-Fonseca, Luís Rocha Lopes

“…<h4>Conclusion</h4>This study provides a framework for scrutinizing variation along the complete intronic sequence of HCM-associated genes and prioritizing candidates for mechanistic and functional analysis. Our data suggest that deep intronic variation contributes to HCM phenotype.…”
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About the use of omega-electroencephalography to estmate functional and metabolic state of nervous tissue of the brain during hyperventilation by S. E. Murik

“…Adaptation to  hypoxia and  ischemia,  modeled  using replication-based HVT,  and  improvement  of brain  resistance  to these  unfavorable  factors  manifested  themselves first in a short-term  electropositive deviation of DCPL at the start  of the test followed by DCPL positivation  reduction and then in complete substitution of electronegative response  to  positive  shift in DCPL (about  0.5 mV) during  the test.Conclusion. The analysis of concomitant changes in DCPL and EEG during and after hyperventilation and literature data  analysis suggests that  HVT  was initially  responded  to  by depolarization in neocortical nerve  cells, combined  with  intensification  of  neuronal  activity. …”
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Clinical trajectories of hand function impairment in systemic sclerosis: an unmet clinical need across disease subsets by Lorraine Green, Ariane L Herrick, Michelle Wilson, Francesco Del Galdo, Enrico De Lorenzis, Philip Helliwell, Benazir Saleem, Emma Derrett-Smith, Begonya Alcacer-Pitarch, Karen Douglas, Vishal Kakkar, Chris Denton, Theresa Barnes, Stefano Di Donato, Muhammad Nisar, Catherine Morley

“…The analysis of factors associated with hand function worsening supports the involvement of both inflammation, vascular and fibrotic processes in hand involvement, making it a hallmark clinical manifestation of SSc. …”
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Impact of remdesivir on liver function: A comparative study of diabetic and non-diabetic COVID-19 patients by Zahra Zarei, Elham Nejadsadeghi, Seyedeh Leila Dehghani, Fateme Dadgar

“…Liver function tests measured key enzymes and substances, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and total bilirubin, and data analysis was performed using SPSS (Confidence Interval = 0.95, p ≤ 0.05). …”
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Cross-sectional associations between multiple plasma heavy metals and lung function among elderly Chinese by Junpu Yu, Rongxuan Zhang, Aimin Yang, Jingli Yang, Yiwen Zhang, Rongjie Wu, Fanhui Luo, Huiling Luo, Rentong Chen, Bin Luo, Li Ma

“…Abstract Environmental exposure to heavy metals may adversely affect lung function particularly in the elderly. However, limited data are available directly evaluating the relationship of heavy metal exposures with lung function in Chinese elderly. …”
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The glucose-to-potassium ratio: a predictor of poor functional outcomes in stroke patients receiving thrombolytic therapy by Dong Zhang, Ruinan Ma, Xiaoyan Qin, Zhizhang Li, Xiaoguang Zhang, Ying Ding, Yunqi Hu, Yunhua Yue

“…The study explores the relationship between admission GPR and 90-day functional outcomes in AIS patients undergoing IVT treatment.MethodsA retrospective analysis included 649 AIS patients undergoing IVT between May 2016 and December 2023. …”
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Pulmonary function in type 2 diabetes mellitus patients: a case-control study in southern Iran by Samrad Mehrabi, Ehsan Alishapour, Mahmood Soveid

“…FVC, FEV1, and FEV1/FVC were measured. The pulmonary function data were compared between groups through a one-way analysis of variance and independent t-test. …”
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Penerapan Quality Function Deployment (QFD) pada Pengembangan Produk Sabun di UKM Kota Batam by Welly Sugianto, Rony Prasetyo

“…The method used is quality function deployment (QFD). The purpose of this study is to design a quality soap product in accordance with customer expectations. …”
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Functional control of the technical condition method for aircraft control system sensors under complete parametric uncertainty by J. V. Bondarenko, E. Yu. Zybin

“…This paper expands the application of the well-known nonparametric failure detection criterion, based on the analysis of the linear dependence of the input-output data Hankel matrix columns and solution of the sensor failures localizing problem. …”
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PSYCHOPHYSIOLOGIC AND IMMUNOLOGIC CHARACTERISTICS IN PATIENTS WITH BRONCHIAL ASTHMA AND IN HEALTHY MEN WITH DIFFERENT FUNCTIONAL ASYMMETRY OF THE HEMISPHERES OF THE BRAIN by A. V. Smyk, T. Ya. Abramova, I. G. Solovjeva, V. M. Nepomnyashchikh, V. S. Trufakin, V. S. Kozhevnikov

“…On the basis of the analysis of own and literary data, proved the interaction psychophysiologic and immunologic parameters in healthy people and in patients with bronchial asthma. …”
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Altered neural oscillation patterns and functional connectivity in postherpetic neuralgia: evidence from resting-state EEG by Fei Gao, Mengru Wang, Huibin Jia, Georgi V. Georgiev, Yi Feng, Wenxia Li

“…Overall, 21 patients with PHN and 17 healthy controls participated in this study. Resting-state EEG data were collected and analyzed. Power spectrum density analysis was conducted to compare frequency band activity, and correlation analyses were used to examine associations between EEG power and psychological symptoms. …”
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