Hepatic irradiation persistently eliminates liver resident NK cells. by Ryosuke Nakano, Masahiro Ohira, Takuya Yano, Yuki Imaoka, Yuka Tanaka, Hideki Ohdan

“…The aim of this study was therefore to investigate how hepatic irradiation influences the functions and characteristics of liver resident NK cells. …”
Get full text

Characteristics and significance of γδ T cells in colorectal cancer by Henna Karjalainen, Jouni Härkönen, Päivi Sirniö, Hanna Elomaa, Ville K. Äijälä, Meeri Kastinen, Vilja V. Tapiainen, Sara A. Väyrynen, Maarit Ahtiainen, Olli Helminen, Erkki-Ville Wirta, Jukka Rintala, Sanna Meriläinen, Juha Saarnio, Tero Rautio, Toni T. Seppälä, Jan Böhm, Jukka-Pekka Mecklin, Anne Tuomisto, Markus J. Mäkinen, Juha P. Väyrynen

“…Their role in cancer remains controversial, since both anti- and protumor functions have been reported. We aimed to shed light on the distinct characteristics of γδ T cells in colorectal cancer (CRC). …”
Get full text

THE INFLUENCE OF CRYOCORSERVED PLACENTA ON THE DYNAMICS OF CHANGES IN CLINICAL INDICATORS IN THE TREATMENT OF PATIENTS WITH PHLEGMONS OF JAW-FACIAL LOCALITIS by V.O. Lychman, K.P. Lokes, D.S. Avetikov, N.V. Gorlach, O.O. Goncharenko, Yu.R. Sharay

“…Circadian clocks affect a wide range of biological processes, including neuronal, endocrine, metabolic, and behavioral functions. One of the key factors influencing behavioral patterns is the chronotype, which is defined as the human circadian typology and is a behavioral manifestation of the human internal circadian clock system that can be assessed using several methodologies that classify people into morning or evening chronotypes[1]. …”
Get full text

Análisis espacial de datos para clasificar Musáceas en zonas Bananeras no tradicionales del Ecuador by Patricia Gómez, Omar Ruíz Barzola, Hernán Garcés, Esther Lilia Peralta García

“…Data were collected in 2009, the sectors where the observations were obtained are: Pallatanga, Bucay, Loja and Zaruma. …”
Get full text

Análisis espacial de datos para clasificar Musáceas en zonas Bananeras no tradicionales del Ecuador by Patricia Gómez, Omar Ruíz Barzola, Hernán Garcés, Esther Lilia Peralta García

“…Data were collected in 2009, the sectors where the observations were obtained are: Pallatanga, Bucay, Loja and Zaruma. …”
Get full text

Análisis espacial de datos para clasificar Musáceas en zonas Bananeras no tradicionales del Ecuador by Patricia Gómez, Omar Ruíz Barzola, Hernán Garcés, Esther Lilia Peralta García

“…Data were collected in 2009, the sectors where the observations were obtained are: Pallatanga, Bucay, Loja and Zaruma. …”
Get full text

Flistory and prospects of development of methods of osteosynthesis and osteosynthesis of the humerus diaphysis by K. I. Khorak, P. G. Kogan, A. R. Lyakh, D. V. Stafeev

“…In the process of writing the article, the analysis of data from literary sources published in the period from 2016 to 2023 was carried out.Results. …”
Get full text

Orchestrators of innovation networks in the city level: the case of Pacto Alegre by Julhete Mignoni, Bruno Anicet Bittencourt, Silvio Bitencourt da Silva, Aurora Carneiro Zen

“…First, the authors identified a role not discussed in the literature, here called the communicator. In the case analysis, the authors observed the communicator role through functions performed by a media partner of the innovation network and by a group of civil society engaged in the city's causes. …”
Get full text

The mediating role of entrepreneurial attitude with entrepreneurial education and self-efficacy on students' entrepreneurial mindset by davoud tahmasebzadeh sheikhlar, mahdiye ruhi, amin parvari

“…Participants were asked to answer the items using a 5-point Likert scale from 1 indicating "strongly disagree" to 5 indicating "strongly agree". The analysis data of this research is in two parts, descriptive and inferential, using SPSS26 software, and in order to test the hypotheses, structural equation modeling using partial least squares method is used using SmartPLS software. …”
Get full text

Prediction of Soil Carbon Sequestration in Rangelands Regarding the Depth and Elevation of Sample Locations using Adaptive Neuro-Fuzzy Inference System (ANFIS) (Case Study: Lar Wat... by zeinab jafarian, zhila ghorbani

“…This system is based on the combination of three components: membership functions of input and output variables (fuzzification), fuzzy rules (rule base), mechanism inference (a combination of rules with fuzzy input), output characteristics, and results of the system (de-fuzzification). …”
Get full text

HIF‐1α‐induced long noncoding RNA LINC02776 promotes drug resistance of ovarian cancer by increasing polyADP‐ribosylation by Yangjun Wu, Yu Zeng, Yong Wu, Xinyu Ha, Zheng Feng, Chaohua Liu, Ziqi Liu, Jiajia Wang, Xingzhu Ju, Shenglin Huang, Linhui Liang, Bin Zheng, Lulu Yang, Jun Wang, Xiaohua Wu, Shengli Li, Hao Wen

“…Methods We performed transcriptome‐wide analysis by RNA sequencing (RNA‐seq) data of platinum‐resistant and ‐sensitive OC tissues. …”
Get full text

Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and 5x-FAD mice by Dilpreet Kour, Dilpreet Kour, Parul Khajuria, Parul Khajuria, Kuhu Sharma, Kuhu Sharma, Alpa Sharma, Alpa Sharma, Ankita Sharma, Ankita Sharma, Syed Mudassir Ali, Priya Wazir, P. Ramajayan, P. Ramajayan, Sanghapal D. Sawant, Sanghapal D. Sawant, Sanghapal D. Sawant, Utpal Nandi, Utpal Nandi, Zabeer Ahmed, Zabeer Ahmed, Ajay Kumar, Ajay Kumar

“…Two months of treatment of 5x-FAD mice with IBC at 25 and 50 mg/kg significantly improved cognitive functions, as evidenced by enhanced memory and motor performance in behavioral tests. …”
Get full text

Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening by Diego Benítez, Jaime Franco, Florencia Sardi, Alejandro Leyva, Rosario Durán, Gahee Choi, Gyongseon Yang, Taehee Kim, Namyoul Kim, Jinyeong Heo, Kideok Kim, Honggun Lee, Inhee Choi, Constantin Radu, David Shum, Joo Hwan No, Marcelo A. Comini

“…Trypanothione synthetase (TryS) catalyses the synthesis of N1,N8-bis(glutathionyl)spermidine (trypanothione), which is the main low molecular mass thiol supporting several redox functions in trypanosomatids. TryS attracts attention as molecular target for drug development against pathogens causing severe and fatal diseases in mammals. …”
Get full text

Integrating network pharmacology, molecular docking and non-targeted serum metabolomics to illustrate pharmacodynamic ingredients and pharmacologic mechanism of Haizao Yuhu Decocti... by Wenbin Huang, Xiaoju Liu, Xingjia Li, Ruixiang Zhang, Guofang Chen, Guofang Chen, Xiaodong Mao, Shuhang Xu, Chao Liu, Chao Liu

“…They were mainly enriched in the biological processes of positive regulation of gene expression, positive regulation of MAPK cascade, signal transduction, protein phosphorylation, negative regulation of apoptotic process, positive regulation of protein kinase B signaling and positive regulation of MAP kinase activity; and molecular functions of identical protein binding, protein serine/threonine/tyrosine kinase activity, protein kinase activity, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding and protein binding. …”
Get full text

Matrix stiffness-dependent PD-L2 deficiency improves SMYD3/xCT-mediated ferroptosis and the efficacy of anti-PD-1 in HCC by Shunxi Wang, Xiaoxue Yuan, Zetao Yang, Xuan Zhang, Zhiling Xu, Li Yang, Xian Yang, Wei Zhou, Wanqian Liu

“…Results: Here, we revealed that matrix stiffness-induced PD-L2 functions as a suppressor of xCT-mediated ferroptosis to promote cancer growth and sorafenib resistance in patients with HCC. …”
Get full text

Multispacecraft Observations of the 27 Day Periodicity in Galactic Protons from 2018 to 2019 by S. Amoroso, M. Babu, S. Bartocci, R. Battiston, S. Beolè, W. J. Burger, D. Campana, P. Cipollone, L. Conti, A. Contin, M. Cristoforetti, C. De Donato, C. De Santis, A. Di Luca, F. M. Follega, G. Gebbia, R. Iuppa, A. Lega, M. Lolli, M. Martucci, G. Masciantonio, M. Mergè, M. Mese, C. Neubüser, R. Nicolaidis, F. Nozzoli, A. Oliva, G. Osteria, F. Palma, B. Panico, F. Perfetto, A. Perinelli, P. Picozza, S. Pietroni, M. Pozzato, E. Ricci, L. Ricci, M. Ricci, S. B. Ricciarini, Z. Sahnoun, U. Savino, V. Scotti, M. Sorbara, A. Sotgiu, R. Sparvoli, P. Ubertini, V. Vilona, S. Zoffoli, P. Zuccon, M. Boezio, R. Munini, O. P. M. Aslam, X. Luo, D. C. Ndiitwani, M. D. Ngobeni, M. Piersanti, M. S. Potgieter, I. I. Ramokgaba

“…Using a time-frequency analysis, we confirm a slight energy dependence for the power of the ∼27 day variation as a function of time, with the periodicity maximum occurring earlier for HEPD-01 than for high-energy data from AMS-02. …”
Get full text

Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis by Jiayu Cao, Yuhui Yang, Xi Liu, Yang Huang, Qianqian Xie, Aliaksei Kadushkin, Mikhail Nedelko, Di Wu, Noel J. Aquilina, Xuehua Li, Xiaoming Cai, Ruibin Li

“…Random forest classification was employed for analyzing in chemico, in vitro and in vivo data to identify predictive descriptors. Results The nano-bio interactions induced diverse changes in the 4 characteristics of MeONPs and had variable effects on the 14 cellular functions, which were quantitatively evaluated in chemico and in vitro. …”
Get full text

Abstract 203: Predicting Outcomes After Mechanical Thrombectomy: Early vs Delayed Neurological Improvement in the SELECT Database by K. Rose Duncan, Deep Pujara, Amrou Sarraj

“…Introduction Understanding of patient benefit and improvement following mechanical thrombectomy in ischemic stroke has made tremendous strides in recent years, however clinicians still struggle to accurately predict patient outcomes and long‐term neurological functioning following large vessel occlusion and endovascular therapy. …”
Get full text

Occurrence of Alternaria Toxins, Ochratoxin A and Aflatoxins B1 in Green Arabic Coffee (Coffea arabica) in Saudi Arabia: Risk Assessment on HepG-2 Cell Line and Male Albino Rats by Ahmed Hashim Almusallam, Ahmed Mahmoud Ismail

“…This work could help fill in data gaps and enhance risk assessment for human health by addressing some of the possible risks associated with Alternaria toxins…”
Get full text

The Relationship Between Psychosocial Factors and Response to Epidural Steroid Injection for Chronic Lumbosacral Radicular Pain: A Prospective Pilot Study by Stensland M, Sanford E, Houle TT, McGeary C, Cobos BA, Lugosi S, Lehman L, Nabity PS, Covell C, Fitzgerald E, Mojallal M, Reed DE, Pangarkar S, Eapen BC, Nanda U, McCormick ZL, McGeary D

“…The primary outcome was pain intensity (numeric rating scale 0– 10). Data were analyzed using principal component analysis and generalized linear mixed-effects modeling.Results: A total of 40 patients (age 52 ± 13.05) participated in this study. …”
Get full text