Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants. by April Kaur Randhawa, Muki S Shey, Alana Keyser, Blas Peixoto, Richard D Wells, Marwou de Kock, Lesedi Lerumo, Jane Hughes, Gregory Hussey, Anthony Hawkridge, Gilla Kaplan, Willem A Hanekom, Thomas R Hawn, South African Tuberculosis Vaccine Initiative Team

“…We examined whether functionally defined TLR pathway polymorphisms were associated with T cell cytokine responses in whole blood stimulated ex vivo with BCG 10 weeks after newborn BCG vaccination of South African infants. …”
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Effective antistress ligands lithium new generation by K. S. Ostrenko, V. A. Galochkin, O. A. Gromova, V. V. Rastashanskii, I. Yu. Torshin

“…The analysis of Literature data and results of own researches of the authors give grounds to conclude that higher stress can be achieved by reducing the Level of free radical oxidation, optimization of Lipid-choLesteroL and hormonal status when using anti-stress drugs of new generation, which incLude organic Lithium saLts. …”
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Social networks of educational purpose as a subject of protection in the preparation of specialists of information security by I. D. Rudinskiy, D. Ya. Okolot

“…The paper also describes threats that may arise when using such networks in an educational organization, suggests measures to mitigate risks and discusses functions of information security specialists in ensuring security of social networks used in the educational process. …”
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Improving the efficiency of multimodal transportation of chemical products from the Volgograd region to the near and far abroad by A. V. Kulikov, P. A. Pavlov, A. A. Kulikov

“…The paper uses methods of statistical and economic analysis of data on the functioning of the chemical industry in the region. …”
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POLYMORPHISM OF THE TP53 GENE IN PATIENTS WITH GASTRIC CANCER IN PROSPECTIVE AND CLINICAL CASE-CONTROL STUDIES by A. V. Belkovets, S. A. Kurilovich, V. N. Maksimov, Yu. I. Ragino, L. V. Scherbakova, O. V. Cheremisina, N. V. Cherdyntseva, M. V. Parulikova, M. I. Voevoda

“…Background. A functionally significant TP53Arg72Pro polymorphism can contribute to the development of gastric cancer (GC).The aim: to study the associations of genotypes and alleles of the TP53Arg72Pro 4 polymorphism with GC and biomarkers of gastric ucosal atrophy in population-based prospective and case-control clinical trials among the population of Siberia.Material and methods. …”
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Preliminary evaluation of a gamified smartphone intervention (O2O-PEP) for enhancing HIV post-exposure prophylaxis uptake in men who have sex with men: pilot feasibility study by Tianyu Cui, Tianying Li, Luyao Gong, Kexiang Wang, Qianqian Luo

“…Regarding the SUS score, 89.5% of participants rated the mini-app within the acceptable usability range (≥ 50), indicating that the majority found the mini-app to be user-friendly. Qualitative analysis of follow-up assessments identified areas where O2O-PEP needed to be improved to enhance user engagement, including a desire to additional functions of psychological and sexual transmitted diseases counseling. …”
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SPHERICAL MICROPARTICLES FROM GOLD–BEARING QUARTZ VEINS OF THE IROKINDA DEPOSIT, WESTERN TRANSBAIKALIA by A. V. Tatarinov, L. I. Yalovik, V. A. Vanin

“…This mechanism, with the exception of the origin of the melt (in this case, of the friction type) seems to most closely correspond to the actual data.  The spheroids are likely to have formed in the pre-ore stage of formation of the quartz veins.The high-temperature metal spherical microparticles revealed in our study can be regarded as specific indicators showing conditions in which the ore-forming system of the dynamo-metamorphic type was functioning to produce gold mineralization on the Irokinda deposit. …”
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Trends and Characteristics of the Migration From Ukraine to Poland: The Aspect of Rural Areas and Conclusion for State Migration Policy by Taras Vasyltsiv, Ruslan Lupak, Olha Levytska

“…The problems and risks for the functioning and development of rural areas of Poland during the strengthening of emigration attitudes and internal mobility of the population are identified. …”
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MiR-195 Inhibits Tumor Growth and Metastasis in Papillary Thyroid Carcinoma Cell Lines by Targeting CCND1 and FGF2 by Yali Yin, Shubin Hong, Shuang Yu, Yanrui Huang, Shuwei Chen, Yujie Liu, Quan Zhang, Yanbing Li, Haipeng Xiao

“…MicroRNA (miRNA) dysregulation was commonly seen in papillary thyroid carcinoma (PTC), and miR-195 was verified to be downregulated in PTC by the large data set analysis from The Cancer Genome Atlas (TCGA). …”
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Traditional Agroforestry Models Based on Local Knowledge in the Mount Mutis-Timau Highlands,Timor Island, Indonesia by Fransiskus Xaverius Dako, Yudhistira A.N.R. Ora, Fabianus Ranta, Yudhistira A.N.R. Ora, Yakub Benu, Blasius Paga, Fredik S. Aramak, Eko Pujiono

“…Willd, Citrus reticulata, Persea americana, Artocarpus heterophyllus, and Mangifera indica) to increase income and ecological functions, and forestry crops (Casuarina junghuhniana, Eucalyptus urophylla, Tectona grandis L.f, and Gmelina arborea), which provide both economic and ecological benefits. …”
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Medial plantar flap for reconstruction of heel defects after resection of acral lentiginous melanoma: A series of seven cases by Giulia Godoy Takahashi, Renan Diego Américo Ribeiro, Vitor Penteado Figueiredo Pagotto, Caio Augusto Lima de Araújo, Fábio de Freitas Busnardo, Rolf Gemperli

“…The tissues on the sole of the foot have unique characteristics essential for maintaining the limbs functionality. The heel has the most significant weight support and is subjected to the entire soles greatest impact. …”
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The long non-coding RNA MALAT1 promotes the migration and invasion of hepatocellular carcinoma by sponging miR-204 and releasing SIRT1 by Zhouhua Hou, Xuwen Xu, Ledu Zhou, Xiaoyu Fu, Shuhui Tao, Jiebin Zhou, Deming Tan, Shuiping Liu

“…Functionally, wound-healing and transwell assays revealed that microRNA-204 significantly inhibited the migration and invasion of hepatocellular carcinoma cells. …”
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Epigenetic Regulation of IL-17-Induced Chemokines in Lung Epithelial Cells by Jiadi Luo, Xiaojing An, Yong Yao, Carla Erb, Annabel Ferguson, Jay K. Kolls, Songqing Fan, Kong Chen

“…Epithelial cells are known to have barrier functions in multiple organs and regulate innate immune responses. …”
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Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway by Manzila Kuerbanjiang, Lei Gu, Chunjie Xu, Wen Ting Xu, Siyuan Wen, Hanbing Xue, Qing Xu

“…Here, we found that MPC2 expression was decreased in CRC samples. According to the analysis on our TMA data, lower expression of MPC2 is correlated with a higher incidence of distant metastasis and lymph node invasion, bigger tumor size, low survival rate of patients, and advanced T stages. …”
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Microstructure, electrical properties, bioactivity, biocompatibility and osteogenic differentiation ability of bio-piezocomposite fabricated by hydroxyapatite and (Ba,Ca)(Ti,Sn)O3-... by Geng Tang, Hong Yang, Bingqing Zhao, Dunying Wang, Fangfang Zeng, Qibin Liu

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Healthcare workers' knowledge and attitudes regarding artificial intelligence adoption in healthcare: A cross-sectional study by Moustaq Karim Khan Rony, Khadiza Akter, Latifun Nesa, Md Tawhidul Islam, Fateha Tuj Johra, Fazila Akter, Muhammad Join Uddin, Jeni Begum, Md. Abdun Noor, Sumon Ahmad, Sabren Mukta Tanha, Most. Tahmina Khatun, Shuvashish Das Bala, Mst. Rina Parvin

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Clinical and laboratory significance of soluble claudin-5 and VEGF in ovarian cancer by N. E. Kushlinskii, S. E. Kulikova, F. A. Gugnin, S. Yu. Nezhdanova, A. N. Gratchev, D. O. Utkin, D. A. Tsekatunov, I. B. Ryzhavskaya, D. N. Kushlinskiy, E. S. Gershtein, I. S. Stilidi

“…Claudin 5 and VEGF levels in serum were measured prior to treatment using Human CLDN5 (Claudin 5) ELISA Kit (Elabscience, China) and Human VEGF Immunoassay (Quantikine®, R&D Systems, uSA) in accordance with the manufacturer’s instructions. Statistical analysis of the obtained data was performed using the GraphPad Prizm v. 10 software. …”
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Multiomics Assessment of the Gut Microbiome in Rare Hyperoxaluric Conditions by Nadim Zaidan, Chan Wang, Ze Chen, John C. Lieske, Dawn Milliner, Barbara Seide, Melody Ho, Huilin Li, Kelly V. Ruggles, Frank Modersitzki, David S. Goldfarb, Martin Blaser, Lama Nazzal

“…Metagenomic (MTG) and metatranscriptomic (MTT) data were processed through our bioinformatics pipelines, and microbiome diversity, differential abundance, and networks were subject to statistical analysis in relationship with oxalate levels. …”
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Detrimental impact on work productivity in patients with glaucoma: a systematic review by Hamza Inayat, Mura Abdul-Nabi, Bernice Leung, Jason Jiang, Sara Robertson, Monali S. Malvankar-Mehta

“…The Modified Downs and Black Checklist was used to evaluate study quality and thematic analysis was used to analyze data. Results: 17 studies met the inclusion criteria. …”
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Insulator BEAF32 regulates expression of tissue-specific genes and piRNA source loci in Drosophila ovaries by Anastasia A. Kobelyatskaya, Valeria Morgunova, Aleksey Kalinkin, Anna A. Shchukina, Olesya Sokolova, Dmitry A. Kwon, Sergei Funikov, Alla Kalmykova

“…Abstract Background Insulators are the multifunctional DNA binding proteins that perform architectural functions and regulate gene transcription. Although insulators have a well-established role in genome organization, it is still unclear how insulator proteins affect the control of tissue-specific processes. …”
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