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14161
Non-invasive urinary proteomic biomarkers for prognostic assessment in sepsis
Published 2025-07-01“…Nomogram model and ROC curves were constructed to evaluate the predictive efficacy of these identified protein biomarkers. …”
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14162
AI in Medical Questionnaires: Innovations, Diagnosis, and Implications
Published 2025-06-01“… This systematic review aimed to explore the current applications, potential benefits, and issues of artificial intelligence (AI) in medical questionnaires, focusing on its role in 3 main functions: assessment, development, and prediction. …”
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14163
Combination of RNA-sequencing data analysis, network pharmacology, molecular docking techniques to investigate the mechanism of Prunella vulgaris L. in the treatment of non-small c...
Published 2025-05-01“…These “drug-disease” common targets were associated with 100 GO items, including 41 biological processes, 16 cellular components, and 43 molecular functions. KEGG enrichment analysis identified 14 signaling pathways. …”
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14164
Formation of a Generalized System of Indicators of Regional Economic Security
Published 2024-11-01“…The topic of the study is relevant, since the prevention of crisis situations, the organization of stable functioning of regional economies, the development of territories and the growth of the standard of living of the population necessitate constant monitoring of the economic security of the regions of Russia, which is based on the modeling of a system of indicators, because socioeconomic development is a complex system of interconnections, various components of the economy.Data and methods. …”
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14165
“It’s like going through life at a mediocre level”: a qualitative study of the meaning and impact of fatigue in children and young people with sickle cell disease
Published 2025-05-01“…Conclusions Fatigue dominates CYP’s experience of living with SCD, significantly impacting their physical, social and educational functioning and leading to isolation and stigma. Often overlooked in clinical settings, addressing fatigue should be integral to SCD care and research. …”
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14166
Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis
Published 2025-05-01“…In this study, we identified several key genes associated with the prognosis of ccRCC by using integrated bioinformatics.MethodsTwo ccRCC expression profiles were downloaded from Gene Expression Omnibus and one dataset was gained from The Cancer Genome Atlas The Robust Rank Aggregation method was used to analyze the three datasets to gain integrated differentially expressed genes The Gene Ontology and KEGG analysis were performed to explore the potential functions of DEGs. The Search Tool for the Retreival of Interacting Genes/Proteins (STRING) and Cytoscape software were used to construct protein-protein interaction network and module analyses to screen the hub genes. …”
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14167
Intelligent Prediction Platform for Sepsis Risk Based on Real-Time Dynamic Temporal Features: Design Study
Published 2025-05-01“…Three linear parameters (mean, SD, and endpoint value) were calculated to construct the prediction model using multiple ML algorithms. …”
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14168
ENSURING PERSONNEL SECURITY OF INDUSTRIAL ENTERPRISES UNDER CONDITIONS OF ENVIRONMENTAL CONFLICTS
Published 2017-09-01“…Personnel security is considered as a synthetic category of economic theory, personnel management, sociology of management and labor economics, and is defined as the activity to create conditions for the stable functioning and development of an enterprise, which ensures the protection of the interests of the enterprise from the risks and threats associated with its own personnel and the personnel themselves from internal and external threats such as blackmail, revenge on competitors, attacks on the lives and health of employees etc. …”
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14169
Machine learning-based radiomics prognostic model for patients with proximal esophageal cancer after definitive chemoradiotherapy
Published 2024-11-01“…Gene ontology enrichment analysis revealed that lipid metabolism-related functions are potentially crucial in the process by which the radiomics score could stratify patients. …”
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14170
Differential expression of five genes during sclerotium formation of Rhizoctonia solani
Published 2013-01-01“…Obviously, complex metabolism and signal transduction pathways are involved in the cell death and the sclerotium formation, the detailed functions of these five genes in the signal transduction pathways leading to the sclerotium formation are still unclear and need to be studied deeply in the future.…”
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14171
Disentangled similarity graph attention heterogeneous biological memory network for predicting disease-associated miRNAs
Published 2024-12-01“…Additionally, various ablation studies were conducted to validate the contributions of different modules within the framework, and’s encoding statuses and memory units of DiGAMN were visualized to explore the utility and functionality of its modules. Case studies confirmed the effectiveness of DiGAMN’s predictions, identifying several new disease-associated miRNAs. …”
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14172
The predictive value of cerebrospinal fluid tap-test in normal pressure hydrocephalus Valor preditivo da punção liquórica ("tap test") na hidrocefalia de pressão normal
Published 1997-06-01“…Prior to operation a cerebrospinal fluid tap-test (CSF-TT) was performed with measurements of gait pattern and psychometric functions (memory, visuo-motor speed and visuo-constructive skills) before and after the removal of 50 ml CSFby lumbar puncture (LP). …”
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14173
Unveiling purine metabolism dysregulation orchestrated immunosuppression in advanced pancreatic cancer and concentrating on the central role of NT5E
Published 2025-04-01“…The by-products of purine metabolic reprogramming are extensively engaged in tumor immune modulation, influencing the functions and recruitment of immune cells and molding an immune microenvironment that is propitious for tumor growth.MethodsWe harnessed single-cell transcriptomics and spatial transcriptomics to concurrently analyze the purine metabolism (PM) features of the PC microenvironment. …”
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14174
Protocol for a cluster-randomized clinical trial to evaluate the effectiveness of mindfulness-based cognitive therapy for depression, implemented in Vietnamese Buddhist pagoda
Published 2025-05-01“…Mindfulness-based interventions are derived from Buddhist meditation but are secular, focused on enhancing emotional and cognitive functioning rather than spiritual growth. The first study goal was to adapt MBCT for use in Buddhist pagoda in Vietnam, a Southeast Asian low- and middle-income country. …”
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14175
Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity
Published 2025-01-01“…Person misfit did not degrade item measures or model statistics. Differential item functioning (DIF) was noted for the three easiest items on specific days. …”
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14176
Psychometric evaluation of the Chinese version of the Patient Self-Advocacy Scale using classical test theory and item response theory
Published 2025-02-01“…The Wright map showed good matching between item difficulty and person ability. Differential item functioning (DIF) analysis revealed no significant differences across gender. …”
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14177
Combining gene expression microarrays and Mendelian randomization: exploring key immune-related genes in multiple sclerosis
Published 2024-11-01“…GO and KEGG analyses were subsequently performed to elucidate the functions and pathways associated with the IM-DEGs. …”
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14178
Are we working (too) comfortably?: the systematic development of an intervention to support workers to move more while working at home
Published 2025-06-01“…In step 4, the intervention functions and behaviour change technique elements of the BCW were used to accurately and consistently specify the active ingredients of the intervention. …”
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14179
Identification and Validation of Feature Genes Related to Mitochondrial Dysfunction and Oxidative Stress in Ulcerative Colitis
Published 2025-04-01“…Given their close association, it is crucial to clarify the molecular characteristics and biological functions of MD and OS-related genes in UC.Methods: Gene expression profiles, mitochondrial-related genes, and OS-related genes were obtained from the corresponding databases. …”
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14180
Models of symmetric three-layer waveguide structures with graded-index core and nonlinear optical liners
Published 2024-10-01“…The analytical methods of mathematical physics and the theory of special functions applied to nonlinear and waveguide optics are used herein.Results. …”
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