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14021
Design of current differential protection system for distribution network based on 5G wireless communication
Published 2025-01-01“…According to the differential protection action criterion calculated by digital signal processing (DSP) controller, the differential protection of distribution network current and related automation functions are completed. The timing module receives Beidou/GPS satellite timing to assist the synchronous sampling of the differential protection modules on both sides of the substation and the switching post. 5G central processing element (CPE) communication module uses 5G wireless communication network to realize data transmission and transmission through the centralized cross domain mapping network architecture in the network slice. …”
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14022
Uricase-Expressing Engineered Macrophages Alleviate Murine Hyperuricemia
Published 2024-11-01“…Serum uric acid and bio-indicators for renal and hepatic functions were detected by an automatic biochemical analyzer; inflammatory cytokines were determined by ELISA; the livers and kidneys of the mice were sectioned for histological examination. …”
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14023
Flu‐CED: A comparative transcriptomics database of influenza virus‐infected human and animal models
Published 2024-12-01“…Using integrated and processed transcriptomic data, we established a user‐friendly website for realizing the integration, online retrieval, visualization, and exploration of gene expression of influenza virus infection in different species and the biological functions involved in differential genes. Flu‐CED can quickly query single and multi‐gene expression profiles, combining different experimental conditions for comparative transcriptome analysis, identifying differentially expressed genes (DEGs) between comparison groups, and conveniently finding DEGs. …”
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14024
Identification of Nuclear Localization Sequence (NLS) Sites in R2R3-MYB Transcription Factor Involved in Anther Development
Published 2025-03-01“…These findings suggest that the NLS at AAs 18–22 is sufficient for nuclear localization. To confirm the NLS functions in vivo, we constructed the vectors including the <i>MS188</i> gene without the NLS sites, which failed to complement the male sterile phenotype of <i>ms188</i>. …”
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14025
Exosomes derived from syncytia induced by SARS-2-S promote the proliferation and metastasis of hepatocellular carcinoma cells
Published 2025-01-01“…Differentially expressed proteins in syncytia-derived exosomes (Syn-Exos) and their functions was analyzed by Proteomic sequencing. Syn-Exo-mediated promotion of hepatocellular carcinoma cells was measured by CCK-8 and Transwell migration assays. …”
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14026
Portable devices for periodic monitoring of bioelectrical impedance along meridian pathways in healthy individuals
Published 2025-01-01“…From a bioelectrical standpoint, this study provides empirical support for the potential existence and functionality of meridians and collaterals, offering a scientific perspective that complements ancient TCM principles.…”
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14027
Some issues of local drinking water supply of the population during martial law (using the example of Ukrainian cities with a population of over 100 thousand people). Part 2
Published 2025-06-01“…The long period of military action in Ukraine has revealed a number of problems associated with the stable functioning of a modern centralized water supply system in emergency situations. …”
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14028
USP14 promotes osteoarthritis progression by deubiquitinating FZD8 to activate the Wnt/β-catenin signaling pathway
Published 2025-05-01“…In this study, we aimed to explore the functions of ubiquitin specific peptidase 14 (USP14) in OA development. …”
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14029
Multiple analytical perspectives of mitochondrial genes in the context of preeclampsia: potential diagnostic markers
Published 2025-07-01“…GO and KEGG analysis were performed to elucidate the functions of the MMRDEGs. A diagnostic model using Random Forest and logistic regression was validated by ROC curve analysis. mRNA expressions of OCRL, TPI1, GAPDH, and LDHA were quantified via qPCR. …”
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14030
FimC binds to the promoter region of agn43 to modulate autoaggregation
Published 2025-05-01“…It also highlights the importance of fimC in the biofilm formation and adhesion ability of APEC, which provides new insights into the functions of the fimbrial chaperone protein FimC.…”
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14031
Identification of matrix stiffness-related molecular subtypes in HCC via integrating multi-omics analysis and machine learning algorithms
Published 2025-07-01“…Distinct immune and mutation landscape characteristics were observed between patients categorized into high and low matrix stiffness groups. PPARG functioned in tumorigenesis through HSC activation and immune suppression. …”
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14032
The stress regulator FgWhi2 and phosphatase FgPsr1 play crucial roles in the regulation of secondary metabolite biosynthesis and the response to fungicides in Fusarium graminearum
Published 2025-08-01“…In this study, we identified homologous genes of WHI2 and PSR1 in F. graminearum and evaluated their functions by constructing deletion mutants. By comparing the responses of the mutants to different stressors, we found that FgWHI2 and FgPSR1 were involved in responding to osmotic, cell wall and cell membrane stresses, while also affecting the sexual and asexual reproduction in F. graminearum. …”
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14033
Mitochondria transplanted adipose-derived stem cells/decellularized adipose tissue hydrogel for adipose tissue regeneration
Published 2025-10-01“…Nevertheless, the therapeutic potential is constrained by the suboptimal functionality of ADSCs, due to the donor health status, long-term culture, and the post-transplantation environment in vivo. …”
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14034
Particle Size Inversion Based on <i>L</i><sub>1,∞</sub>-Constrained Regularization Model in Dynamic Light Scattering
Published 2024-11-01“…Dynamic light scattering (DLS) is a highly efficient approach for extracting particle size distributions (PSDs) from autocorrelation functions (ACFs) to measure nanoparticle particles. …”
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14035
Deciphering organic substrate impacts in Anammox systems: A machine learning driven framework for predictive classification and process mechanism analysis
Published 2025-08-01“…In summary, machine learning framework effectively integrates and optimizes the regulation of material stoichiometry, environmental parameters, and microbial functionality, thereby advancing the development of energy-efficient nitrogen removal technologies and enhancing the evaluation system for wastewater treatment processes.…”
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14036
Metal–organic nanostructures based on sono/chemo-nanodynamic synergy of TixOy/Ru reaction units: for ultrasound-induced dynamic cancer therapy
Published 2025-07-01“…In this study, we innovatively designed a multifunctional metal–organic nanosheet (TiZrRu-MON) by hydrothermal coordination of [Ru(bpy)₃]2⁺ photosensitizing units with TiZr-O clusters, while incorporating Fe3⁺ to construct a cascade catalytic system. Experimental results demonstrated that: (1) Fe3⁺ lattice doping significantly enhanced charge carrier mobility and ultrasound-triggered 1O₂ quantum yield via the formation charge transfer channels; (2) The acidic tumor microenvironment activated Fe3⁺-mediated Fenton reactions, establishing a positive feedback loop with SDT to synergistically amplify ROS generation; (3) Hyaluronic acid functionalization improved nanosheet internalization in HepG2 tumor cells through CD44 receptor-mediated endocytosis. …”
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14037
KnowVID-19: A Knowledge-Based System to Extract Targeted COVID-19 Information from Online Medical Repositories
Published 2024-11-01“…The system utilizes various open-source machine learning tools, such as GROBID, S2ORC, and BioC to streamline the processes of data extraction and data mining. Central to the functionality of KnowVID-19 is its keyword-based text classification process, which plays a pivotal role in organizing and categorizing the extracted information. …”
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14038
Advancements in chondrocyte 3-dimensional embedded culture: Implications for tissue engineering and regenerative medicine
Published 2025-04-01“…However, in 2D culture, chondrocytes tend to lose their distinctive phenotypes and functionalities after serial passage, thereby limiting their efficacy for tissue engineering purposes.The mechanism of dedifferentiation in 2D culture can be attributed to various factors, including abnormal nuclear strength, stress-induced mitochondrial impairment, chromatin remodeling, ERK-1/2 and the p38/mitogen-activated protein kinase (MAPK) signaling pathway. …”
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14039
Deletion of the transcription factor ATF4 in a model of clear cell renal cell carcinoma
Published 2025-08-01“…Additionally, we reported that ATF4 (activating transcription factor 4), a transcription factor, and its target genes were highly expressed both in human ccRCCs and in TRACK PT cells. To delineate the functions of ATF4 in ccRCC we have now generated TRACK mice in which the ATF4 gene is specifically deleted in PT cells (GCREA∆T). …”
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14040
CME Velocity Field Calculation Model Based on an Unsupervised Transformer Optical Flow Network
Published 2024-01-01“…Therefore, we apply fluid motion–based loss functions to analyze the motion of high-energy particles more effectively, addressing the problem of CME motion field extraction. …”
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