GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…Further analyses, including GO and KEGG pathway enrichment, protein-protein interaction (PPI) network construction, hub gene identification, as well as miRNA and transcription factor prediction and drug candidate screening, were conducted. …”
Get full text

Downregulation of hsa-miR-135b-5p Inhibits Cell Proliferation, Migration, and Invasion in Colon Adenocarcinoma by Yunxin Zhang, Wentao Zhang, Wenlong Xia, Junwei Xia, Haishan Zhang

“…Therefore, downregulation of hsa-miR-135b-5p inhibits cell proliferation, migration, and invasion in COAD, and carcinogenesis may function by targeting FOXN2, NSA2, MYCBP, DIRAS2, DESI1, and RAB33B.…”
Get full text

Simulation of potential suitable areas and analysis of natural reserves for four species of Taxus in southern China by Yuchen Zhou, Yuchen Zhou, Juhua Hu, Guanhong Xie, Yakui Shao, Mu Liu

“…The model’s accuracy was validated using the Area Under the Receiver Operating Characteristic Curve (AUC) to compare the effect of different function models on prediction accuracy.ResultsThe results showed that the AUC values for all four yew species exceeded 0.9, indicating a high level of reliability in the model predictions. …”
Get full text

Acoustical modelling of the surface sources – IV. Interpolation model, axisymmetric problem by A. BRAŃSKI

“…In the paper, the quadratic shape function were applied to construct an interpolation model of a plane axisymmetric source. …”
Get full text

Deficiency of myeloid NPC1 exacerbates liver injury and fibrosis by impairing macrophage efferocytosis by Dongwei Guan, Pengju Huang, Xinlei Liu, Qing Li, Xiaoxun Zhang, Nan Liu, Yong Wang, Ying Wan, Jin Chai, Shiying Cai, Rui Chen, Zhijia Ye

“…Myeloid cell-specific Npc1 knockout mice were constructed to determine the functional role of macrophage NPC1 in liver injury. …”
Get full text

Cancer cell membrane-coated siRNA-Decorated Au/MnO2 nanosensitizers for synergistically enhanced radio-immunotherapy of breast cancer by Diyu Wang, Subin Lin, Tuanwei Li, Xiaohu Yang, Xiang Zhong, Qian Chen, Guoqin Jiang, Chunyan Li

“…In the integrated nanosensitizer, the cancer cell membrane (CM) derived from 4T1 breast cancer cells is utilized for targeted functionality, while Au/MnO2 is designed to improve X-ray absorption and alleviate tumor hypoxia. …”
Get full text

Bioinformatics-Based Identification of CircRNA-MicroRNA-mRNA Network for Calcific Aortic Valve Disease by Linghong Song, Yubing Wang, Yufei Feng, Hao Peng, Chengyan Wang, Juncang Duan, Kejian Liu, Xihua Shen, Wenyi Gu, Yan Qi, Shan Jin, Lijuan Pang

“…Based on the online website prediction function, the common mRNAs (FmRNAs) for constructing circRNA-miRNA-mRNA networks were identified. …”
Get full text

Colloquial Emotive Lexicon of Russian in Aspect of Polyparadigmality: Lexicographic Perspective (Thesaurus Dictionary “Emotion Alphabet”) by L. G. Babenko, V. V. Danilova

“…This allows for presenting colloquial emotive lexicon as an overlapping set of various groups of lexemes: denotative-ideographic, cognitive-derivational, semantic-functional, and functional-stylistic. Trends and cognitive strategies in the formation of this set are identified in comparison with literary language. …”
Get full text

Boredom and curiosity: the hunger and the appetite for information by Johannes P.-H. Seiler, Ohad Dan

“…Boredom and curiosity are common everyday states that drive individuals to seek information. Due to their functional relatedness, it is not trivial to distinguish whether an action, for instance in the context of a behavioral experiment, is driven by boredom or curiosity. …”
Get full text

Neuroscience applied to learning alphabetic principles: new proposals by Leonor Scliar-Cabral

“…    This study reviews recent data on functional illiteracy and advances on neuroscience about the reading process. alarming figures on functional illiteracy will be presented with examples of UK and brazil. …”
Get full text

UFO: A tool for unifying biomedical ontology-based semantic similarity calculation, enrichment analysis and visualization. by Duc-Hau Le

“…Moreover, UFO can visualize structural relationships between ontology terms, annotating relationships between entities and terms, and functional similarity between entities. Finally, we demonstrated the ability of UFO through some case studies on finding the best semantic similarity measures for assessing the similarity between human disease phenotypes, constructing biomedical entity functional similarity networks for predicting disease-associated biomarkers, and performing enrichment analysis on a set of similar phenotypes.…”
Get full text

The Heat Equation Solution Near the Interface Between Two Media by Natalia T. Levashova, Olga A. Nikolaeva

“…A function  with this feature  can be a solution to the problem for the heat equation  with a discontinuous thermal diffusivity and discontinuous function  describing  heat  sources.  …”
Get full text

A New Global Optimization Algorithm for Solving a Class of Nonconvex Programming Problems by Xue-Gang Zhou, Bing-Yuan Cao

“…Firstly, a two-part parametric linearization method is adopted to construct the underestimator of objective and constraint functions, by utilizing a transformation and a parametric linear upper bounding function (LUBF) and a linear lower bounding function (LLBF) of a natural logarithm function and an exponential function with e as the base, respectively. …”
Get full text

Study on the Macromesoscopic Yield Criterion of Concrete Material by Xia XiaoZhou, Zhang Qing, Jiang Qun, Xiao JianQiang

“…In order to solve the nonderivability on the yield boundary, the function approximation series has been constructed to substitute for the energy density support function. …”
Get full text

Metagenomic analysis revealing the metabolic role of microbial communities in the free amino acid biosynthesis of Monascus rice vinegar during fermentation by Hang Gao, Jian Zhang, Li Liu, Lijun Fu, Yan Zhao, Germán Mazza, Xin Zhang

“…The results revealed that 5 functional genera were closely involved in FAA biosynthesis. …”
Get full text

Multi-omics investigation reveals unique markers in Klebsiella pneumoniae compared to closely related species by Lena-Sophie Swiatek, Kristin Surmann, Elias Eger, Justus U. Müller, Manuela Gesell Salazar, Stefan E. Heiden, Guido Werner, Nils-Olaf Hübner, Jürgen A. Bohnert, Karsten Becker, Uwe Völker, Michael Schwabe, Katharina Schaufler, Katharina Schaufler

Get full text

Failure Assessment for the High-Strength Pipelines with Constant-Depth Circumferential Surface Cracks by X. Liu, Z. X. Lu, Y. Chen, Y. L. Sui, L. H. Dai

“…The values of elastic influence functions for stress intensity factor and plastic influence functions for fully plastic J-integral estimation are derived in tabulated forms through a series of three-dimensional finite element calculations for different crack geometries and material properties. …”
Get full text

Psychometric properties of the exercise self-efficacy scale in patients with chronic obstructive pulmonary disease. by Cristina Sacristán-Galisteo, Tamara Del Corral, Ibai López-de-Uralde-Villanueva, M Carmen Gómez, Patricia Martín-Casas

“…The secondary objective was to evaluate the relationship between self-efficacy, functional exercise capacity, health-related quality of life and psychological state in the same population.…”
Get full text

Identified a novel prognostic model of HCC basing on virus signature for guiding immunotherapy by Shizhuan Huang, Dehai Wu, Guanqun Liao, Ming Liang, Yaohui Zhang, Haotian Wu, Daowei Tang, Dixiang Wen, Bo Jiang, Shan Yu, Sheng Tai

“…Microbiome and RNA sequencing data and clinical information were obtained from The Cancer Genome Atlas, and viruses with prognostic value were identified (Deltabaculovirus, Sicinivirus, and Cytomegalovirus) to construct the prognostic model. Correlation analyses were performed to evaluate the predictive function of the viral signature. …”
Get full text

Randomised control trial of virtual reality in cognitive rehabilitation: effectiveness and near-transfer effect for stroke patients by Jovita Janavičiūtė-Pužauskė, Raimonda Petrolienė, Loreta Zajančkauskaitė-Staskevičienė, Andrius Paulauskas, Liuda Šinkariova

“…Evaluations were performed before (at the beginning of rehabilitation for control group) and after the intervention (two weeks after pre-test for control group). The target functions included the changes in short-term visual memory, visual-spatial attention, attention-orientation, while near transfer effect included the changes in visuo-construction abilities, task switching, verbal memory, verbal fluency, language, visuo-spatial abilities, general cognitive function. …”
Get full text