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5461
Silencing RPL11 attenuates acute kidney injury by suppressing tubular apoptosis and macrophage-driven inflammation
Published 2025-08-01“…Technologies such as Western blotting, qPCR, and IVS fluorescence imaging ensure the successful construction of cell and animal models. Functional testing includes CCK-8, EdU assay, flow cytometry, TUNEL assay, qPCR, ELISA, and histopathological techniques to evaluate cell proliferation, apoptosis, and inflammatory cytokine levels.ResultsRPL11 was identified as the core gene with AKI-specific upregulation in proximal tubules. …”
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5462
Identification of key LncRNAs and mRNAs in fat deposition of Saba pigs based on comparative analysis of transcriptomics
Published 2024-12-01“…We employed cis-regulatory analysis to explore the function of LncRNAs. Gene Ontology (GO) enrichment revealed pathways and enzyme activity-related terms, indicating that LncRNAs may modulate gene expression to influence biological processes. …”
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5463
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5464
Soils of the Settlements of the Yamal Region (Russia): Morphology, Diversity, and Their Environmental Role
Published 2025-08-01“…Surprisingly, the forms of urban soil formation in the Arctic are very diversified in terms of morphology, as well as in the ecological functions performed by soils. The urbanization of past decades has drastically changed the local soil cover.…”
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5465
Analysis of Offshore Pile–Soil Interaction Using Artificial Neural Network
Published 2025-05-01“…Traditional p-y curve methods, with simplified fitting functions, inadequately capture the complex pile–soil behaviors, limiting predictive accuracy and model uncertainty quantification. …”
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5466
GBsim: A Robust GCN-BERT Approach for Cross-Architecture Binary Code Similarity Analysis
Published 2025-04-01“…Nevertheless, practical deployments in mission-critical scenarios such as binary code similarity detection face two fundamental obstacles: first, the inherent noise in graph construction processes exemplified by incomplete control flow edges during binary function recovery; second, the substantial distribution discrepancies caused by cross-architecture instruction set variations. …”
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5467
Improved Quantum Query Upper Bounds Based on Classical Decision Trees
Published 2025-06-01“…We also show a polynomial separation between rank and randomized rank for the complete binary AND-OR tree. Beigi and Taghavi constructed span programs and dual adversary solutions for Boolean functions given classical decision trees computing them and an assignment of non-negative weights to its edges. …”
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5468
The method of determining the forces in the tendon apparatus of human fingers
Published 2023-09-01“…Being one of the most functionally loaded systems, the human hand and its anatomical structures are damaged quite often. …”
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5469
Stress strain state of double-layered ferrocement shells under the fire condition
Published 2022-05-01“…The physically nonlinear problem reduces to the sequential solution of elastic problems for a structure whose physicomechanical parameters are functions of the x, y, z coordinates. The solution is carried out by the finite element method in combination with the Newton-Raphson method. …”
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5470
Development of an interactive biosensing application for assessing finger dexterity
Published 2025-02-01“…Data were collected for the dominant hand from a large cohort of healthy volunteers to establish population norms values. Results The construction of the application involved a comprehensive, multi-stage process designed to ensure functionality, user-friendliness, and cross-platform compatibility using the Flutter framework by Google with specific adaptations for Android and iOS. …”
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5471
Sistemnyy podkhod k postroeniyu ontologii dlya avtomatizatsii sostavleniya raspisaniya mnogourovnevogo vuza
Published 2025-12-01“…The construction of a university class schedule is one of the NP-complete problems. …”
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5472
Istanbul Residents’ Aesthetic and Architectural Concerns Regarding the Establishment of Municipalities in the City: The Opinions of Ahmed Lütfi Efendi
Published 2022-01-01“…The Ottoman Empire maintained this identity by preserving the old structures, using them with different functions, and establishing new buildings, giving the city an Islamic identity in time. …”
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5473
Spatial Analysis of Physical Quality of Rural Housing in Iran
Published 2015-09-01“…Housing enjoys a multilateral functioning in the rural system. One of the aspects highlighted by planning system is the renewal and rehabilitation of housing. …”
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5474
Asymmetric synthesis of allylic sulfonamides with axially and central chirality via palladium-catalyzed of atroposelective N-allylic alkylation
Published 2025-05-01“…Axially chiral anilide compounds are an emerging but scarcely investigated class of stereogenic molecules with potential applications as chiral catalysts, biologically active scaffolds and functional materials. Compared to the C–C axially chiral molecules, the synthesis of axially chiral anilide compounds is a challenge owing to the lower rotation barriers. …”
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5475
Over 100 years of longitudinal connectivity changes from the perspective of a migratory fish species
Published 2025-06-01“…For this purpose, a graph theoretic approach is deployed that integrates structural and functional aspects, illustrating connectivity changes from the perspective of a characteristic migratory fish species Chondrostoma nasus (Linnaeus 1758). …”
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5476
Réseaux sociaux en ligne et espace distancié d'apprentissage – Quelle transférabilité ?
Published 2012-06-01“…The creation of a synergy between e-learning and the Web using existing social networks would seem to be increasingly plausible with the development of Web 2.0 functionalities. The paper analyses two attempts at such a transfer, showing to what extent practicability can be dependent on the context of emergence and how transferability is dependent upon a built-in "continuum" of interpretation, taking reusability into account. …”
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5478
Thermal Performances of UHMWPE/BN Composites Obtained from Different Blending Methods
Published 2019-01-01“…Moreover, the thermal stability of composites by SM is improved with the increment of BN content, which is better than that of samples by MM, probably resulting from the barrier function of the segregated structure.…”
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5479
Stereodivergent synthesis of benzylic alcohol derivatives enabled by Pd/Cu co-catalyzed asymmetric benzylic substitution reaction
Published 2025-07-01“…Furthermore, density functional theory (DFT) calculations reveal that the stereochemical outcome of the reaction is governed by the nucleophilic attack on the key η³-oxybenzyl-Pd intermediate.…”
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5480
Triclosan exposure potentiates ischemic stroke risk: Multi-omics integration and molecular docking unveil neurotoxic mechanisms
Published 2025-09-01“…A predictive model for TCS-associated IS risk was developed, complemented by mechanistic insights through the construction of miRNA-TF-mRNA regulatory networks and GeneMANIA functional prediction maps. …”
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