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4441
Investigating the role and mechanisms of bisphenol compounds in premature ovarian insufficiency using computational biology and bioinformatics
Published 2025-02-01“…Premature Ovarian Insufficiency refers to the premature decline in ovarian function before the age of 40, resulting in menstrual irregularities or complete cessation of menstruation, and affecting fertility. …”
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4442
Neural operators for hydrodynamic modeling of underground gas storage facilities
Published 2024-12-01“…One of the most promising approaches involves the construction of neural operators, i.e., a generalization of neural networks to approximate mappings between functional spaces. …”
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4443
A Dissipative Particle Dynamics Study on the Formation of the Water-In-Petroleum Emulsion: The Contribution of the Oil
Published 2025-05-01“…In this study, the formation and stabilization mechanisms of water-in-oil HIPEs were investigated using a multiscale modeling approach that combines dissipative particle dynamics (DPD), molecular dynamics (MD), and density functional theory (DFT). Fourteen oil types and six polyaromatic emulsifiers with varying side-chain configurations and polar functional groups were modeled. …”
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4444
FIRST TIME EXPERIMENTAL IMPLANTING OF LOCALLY DEVELOPED LEFT ATRIUM OCCLUDERS
Published 2016-12-01“…The experience of occluder preclinical test showed its construction and functional effectiveness for the aim of further usage in patients with high risk of cardioembolic strokes due to LAA thrombosis. …”
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4445
CRISPR/Cas9-based discovery of ccRCC therapeutic opportunities through molecular mechanism and immune microenvironment analysis
Published 2025-07-01“…Initial screening identified 11 candidate genes through differential expression analysis and CRISPR functional validation. Using LASSO and Cox regression, we selected five key genes (GGT6, HAO2, SLPI, MELK, and EIF4A1) for model construction. …”
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4446
Design of a public health emergency equipment system for bioterrorism events in public places based on literature review, scenario analysis and Delphi consultation
Published 2024-10-01“…The coordination coefficients of the expert opinions were 0.226 and 0.258, respectively (both P < 0.001), indicating a good degree of coordination among the expert opinions. Ultimately, 32 functional units were constructed, including five aspects: investigation, testing, decontamination, protection, and treatment, and a health emergency equipment system for major public bioterrorism events was constructed, consisting of 162 units/sets of instruments or equipment. …”
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4447
Comprehensive analysis of IRF8-related genes and immune characteristics in lupus nephritis
Published 2024-12-01“…Objective: We aimed to explore gene networks and potential biomarkers for LN by analyzing the GSE32591 and GSE113342 datasets from the Gene Expression Omnibus database, focusing on IRF8 and IRF8-related genes.MethodsWe used differential expression analysis, functional enrichment, protein-protein interaction (PPI) network construction, and the CIBERSORT algorithm for immune infiltration assessment. …”
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4448
Development of an evaluation list for older adult community-based rehabilitation needs through a Delphi method
Published 2024-10-01“…The International Classification of Functioning, Disability, and Health (ICF) was used to construct a first draft of the assessment list. …”
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4449
Theory of Nonlocal Point Transformations in General Relativity
Published 2016-01-01“…A discussion of the functional setting customarily adopted in General Relativity (GR) is proposed. …”
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4450
Experiences of teaching innovation for the consolidation of a R&D&I culture
Published 2017-06-01“…The project was developed in six phases, with 60 work teams, obtaining 60 functional prototypes, distributed in the following categories: 8 Agroindustry and food Service, 8 APPS and Software development, 8 Biotechnology, 15 Energies for the future, 7 of social innovation, 7 of new materials for construction, and 7 of Robotic. …”
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4451
Using GNN property predictors as molecule generators
Published 2025-05-01“…We demonstrate the application of this method by generating molecules with specific energy gaps verified with density functional theory (DFT) and with specific octanol-water partition coefficients (logP). …”
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4452
Pore structure characterization of porous building material by X-ray computed tomography (XCT) and X-ray microscopy (XRM)
Published 2025-02-01“… The pore structure of porous building materials, with pore elements ranging from nanometer to millimeter scale, often is a crucial factor that impacts the material’s functional properties. This paper extensively characterizes the pore structure of ceramic brick, a commonly applied porous building material. …”
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4453
Web-search and address distribution of information on the basis of modeling of verbal associations
Published 2019-09-01“…A mathematical model is proposed for the processes of websites scanning and addressing (selective) distribution of the text information found after the request of users in the form of their information profiles, i. e. accumulated archives of relevant Internet publications. The functional components of such an information system are three subsystems: the subsystem of texts indexing, user archives and short messages; web page scanning subsystem; the subsystem of address distribution of texts and short messages to users. …”
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4454
Computer‐aided rational design of the phosphotransferase system for enhanced glucose uptake in Escherichia coli
Published 2008-01-01“…Assuming that the PTS aims at controlling the glucose uptake rate, the PTS was decomposed into hierarchical modules, functional and flux modules, and the effect of changes in gene expression on the glucose uptake rate was simulated to make a rational strategy of how the gene regulatory network is engineered. …”
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4455
A regional design method for Chinese traditional dwellings using the WSR system approach
Published 2025-06-01“…By combining vernacular design elements with contemporary construction techniques, the project emphasizes the coexistence of cultural continuity and functional upgrades. …”
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4456
L’autoconfrontation croisée comme instrument d’action au travers du dialogue
Published 2010-09-01“…We also make the assumption of cross-functional relationships between dialogue and action. …”
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4457
Identification of STAT3 signaling as a shared pathogenic signature in systemic lupus erythematosus, chronic obstructive pulmonary disease, and asthma
Published 2025-07-01“…Functional enrichment analysis of the shared PPI network of SLE, COPD, and asthma revealed involvement of the shared DEGs in the activation of innate immunity in conjunction with the dysregulation of adaptive immunity, specifically the differentiation of Th1, Th2, and Th17 cells. …”
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4458
The Role of Street Art in Artistic Design Citizen Experience in the City
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4459
Evaluation of Positioning Accuracy Using Smartphone RGB and LiDAR Sensors with the viDoc RTK Rover
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4460
Development of Optimal Size Range of Modules for Driving of Automatic Sliding Doors
Published 2025-04-01“…To solve the problem, a developed approach is used, composed of several stages: determining the main parameter of the product; market demand study; selection of an optimality criterion—the total costs for production and operation; determining the functional dependence between the costs and the influencing factors; and building a mathematical model of the problem. …”
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