Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change by Muhammad Abubakkar Azmat, Malaika Zaheer, Muhammad Shaban, Saman Arshad, Muhammad Hasan, Alyan Ashraf, Muhammad Naeem, Aftab Ahmad, Nayla Munawar

“…This process is arbitrated by the conserved machinery of basic autophagy-related genes (ATGs). …”
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Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus. by Elizabeth R Sturgill, Daniel Malouli, Scott G Hansen, Benjamin J Burwitz, Seongkyung Seo, Christine L Schneider, Jennie L Womack, Marieke C Verweij, Abigail B Ventura, Amruta Bhusari, Krystal M Jeffries, Alfred W Legasse, Michael K Axthelm, Amy W Hudson, Jonah B Sacha, Louis J Picker, Klaus Früh

“…However, infection can be rescued by replacing Rh159 with HCMV UL16 suggesting that Rh159 and UL16 perform similar functions in vivo. We therefore conclude that cytomegaloviral interference with NK cell activation is essential to establish but not to maintain chronic infection.…”
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Context-dependent autophagy in cancer: deciphering cytoprotective vs. cytotoxic roles and therapeutic modulation strategies by Samer Osama Kostandy, Salwa Aburageh Abuiessa, Mai Mostafa Helmy, Maged Wasfy Helmy

“…<p>Autophagy is a highly conserved cellular process activated when cells are exposed to stress. …”
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Local and global sensitivity analysis of key durability parameters of concrete under chloride environment by Lingjie Wu, Chengjian Yu, Fenfei Shi, Xuping Ni

“…Results demonstrate that parameter distribution functions and coefficients of variation (COV) significantly alter sensitivity outcomes, with parameter interactions amplifying or mitigating individual effects. …”
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GPR139 agonist and antagonist differentially regulate retrieval and consolidation of fear memory in the zebrafish by Nisa Roy, Satoshi Ogawa, Sachiko Tsuda, Ishwar S. Parhar

“…G protein-coupled receptor 139 (GPR139), a highly conserved orphan receptor, is predominantly expressed in the habenula of vertebrate species. …”
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Genome-wide identification and expression analysis of growth-regulating factor (GRF) and GRF-interacting factor (GIF) gene families in Castanea mollissima by WANG Xiangyu, TIAN Yujuan, LI Yun, WANG Dongsheng, WANG Xuan, GUO Chunlei, LIU Jing, ZHANG Hai’e, ZHANG Jingzheng, YU Liyang

“…In this study, the Chinese chestnut GRF and GIF gene families were studied to provide a theoretical basis for analyzing the potential functions of GRF and GIF genes in Chinese chestnut development and response to environmental stresses. …”
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Can Historical Environments Rival Natural Environments? An Empirical Study on the Impact of Campus Environment Types on College Students’ Mental Health by Chuqi Zhong, Ruiqi Zhang, Shaoying Lu, Hao Zeng, Wei Gao

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Glutathione S-transferase in mediating adaptive responses of oats (Avena sativa) to osmotic and cadmium stress: genome-wide analysis by Chenbiao Xu, Lyu Jiang, Aixue Li, Jie Meng, Ping Yun, Jianfang Li, Changbin Liu, Yang Chen, Han Zhang, Hassan Ahmed Ibraheem Ahmed, Quan Gao, Lana Shabala, Sergey Shabala, Bin Luo, Peichen Hou

“…Phylogenetic analysis revealed that AsGSTs exhibit significant similarity to corresponding GST categories in Arabidopsis thaliana and Oryza sativa, indicating a possible common ancestor. Gene structure and conserved motif analysis demonstrated that AsGST genes within the same subfamily shares similarities in the number and positioning of exons and introns, as well as in motif composition, suggesting that these genes may perform analogous biological functions in A. sativa. …”
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Automobile Paint Reducer Induced Acute Kidney Injury by Muzamil Latief, Zhahid Hassan, Mohd Latief Wani, Farhat Abbas, Summyia Farooq

“…All the patients eventually recovered their kidney functions and were doing well during their follow-up. …”
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In Silico identification and characterization of SOS gene family in soybean: Potential of calcium in salinity stress mitigation. by Anam Hameed, M Asaf Khan, M Hammad Nadeem Tahir, Madeeha Shahzad Lodhi, Saima Muzammil, Muhammad Shafiq, Tsanko Gechev, Muhammad Faisal

“…Further phylogeny and in silico analyses showed that GmSOS orthologs contain similar gene structures, close evolutionary relationship, and same conserved motifs, reinforcing that GmSOSs belong to SOS family and they share many common features with orthologs from other species thus may perform similar functions. …”
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Impact of Shari’ah and Corporate Governance on Islamic Banks Performance: Evidence from Pakistan by Asia Rani, Samina Bibi, Syed Burhan Gilani, Junaid Shahid

“…Findings: The conclusion of the study establishes that Shari’ah governance factors especially the functioning of Shari’ah boards have bigger impact toward financial performance of Islamic banks than corporate governance factors. …”
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Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling. by Mei Li, Xiaoyan Hu, Xinxin Hu, Fuhua Gao, Ying Cui, Xiaoqing Wei, Yuanhua Qin, Xiaohua An, Ying Zhao, Ying Gao

“…However, the expression and biological functions of PHB1/PHB2 in atherosclerosis (AS) remain unclear. …”
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Intravitreal Ranibizumab for Treatment of Posttraumatic Choroidal Neovascularization: a Case Report by A. N. Kulikov, A. Yu. Kuznetsova, N. A. Nekrash, D. S. Maltsev

“…Despite the favorable result of treatment, further monitoring of the patient is necessary, since the long-term prospects for maintaining the achieved high visual functions remain unclear due to the insufficient experience in treating patients with this pathology according to the literature.…”
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Information and Life: Towards a Biological Understanding of Informational Phenomena by Pedro C. Marijuán

“…Thus, the new knowledge gained on the functionality and “existential flow” of the phenotypic molecular elements (basically the production and degradation of constituent enzymes and proteins—the transient proteome of the cell), which is intimately coupled with the intrinsic dynamics of the “DNA world” and with the communicational events stemming from the cell environment, could represent a microcosm for the whole in-formation phenomena. …”
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Telmisartan Modulates Glial Activation: In Vitro and In Vivo Studies. by Nofar Torika, Keren Asraf, Abraham Danon, Ron N Apte, Sigal Fleisher-Berkovich

“…The circulating renin-angiotensin system (RAS), including the biologically active angiotensin II, is a fundamental regulatory mechanism of blood pressure conserved through evolution. Angiotensin II components of the RAS have also been identified in the brain. …”
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The pasture-type approach for mountain pasture description and management by Giovanni Argenti, Giampiero Lombardi

“…The pasture-type approach may play an important role in defining the management of mountain and marginal environments where grazing pressure reduction remarkably affects the agro-ecosystems functions (production, landscape, wildlife, recreation, etc.). …”
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Long-Term Persistence in Observed Temperature and Precipitation Series by Huayu Zhong, Yiping Guo

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Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells. by Lara Wohlbold, Karl A Merrick, Saurav De, Ramon Amat, Jun Hyun Kim, Stéphane Larochelle, Jasmina J Allen, Chao Zhang, Kevan M Shokat, John H J Petrini, Robert P Fisher

“…It remains difficult, however, to assign precise functions to specific CDKs in protecting genomic integrity. …”
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Implementation of a wireless sensor network for irrigation management in drip irrigation systems by Mehmet Kamil Meriç

“…The hardware and software designs of the soil moisture monitoring and valve control nodes were created, including the selection of components, specific functionalities of software algorithms, and communication protocols used for data transmission. …”
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Development of KCC2 therapeutics to treat neurological disorders by Shilpa D. Kadam, Shane V. Hegarty

“…This causes neuronal hyperexcitability, disinhibition within neuron circuits, and disrupted neurological functions. More recently, KCC2 was identified as a genetically-validated target for epilepsy, intellectual disability, and autism spectrum disorder, and pathogenic mutations in human SLC12A5 gene were linked to psychiatric/mood disorders. …”
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