Nuclear receptor signaling regulates compartmentalized phosphatidylcholine remodeling to facilitate thermosensitive lipid droplet fusion by Qi Li, Xiaofang Zhou, Xiaocong Zhang, Chuqi Zhang, Shaobing O. Zhang

“…How the phospholipid monolayer membrane of LD functions in fusion, however, is poorly understood. …”
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Bacteriome Diversity of Soil Islands Associated With Bromeliads From Ironstone Outcrops in the Brazilian Pantanal by Fernanda M. R. Godoy, Gecele M. Paggi, Aline P. Lorenz, Jeferson V. Ramos, Daniel G. Franco, Fernando M. L. Calarge, Nayara F. L. Garcia, Marcus V. S. Urquiza, Jolimar A. Schiavo, Nalvo F. Almeida, Marivaine S. Brasil

“…Knowledge about the diversity and distribution of microorganisms in natural environments is essential for understanding the dominant microbial groups and predicting their ecological functions. This study is aimed at describing the bacteriome diversity in soils associated with bromeliads in the Brazilian Pantanal region, utilizing genomic approaches. …”
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Y-box Protein-1 Regulates the Expression of Collagen I in Hepatic Progenitor Cells via PDGFR-β/ERK/p90RSK Signalling by Fei Li, Zhenzeng Ma, Heng Liu, Qidi Zhang, Xiaobo Cai, Ying Qu, Mingyi Xu, Lungen Lu

“…This study aims to explore the functions of YB-1 in hepatic progenitor cells (HPCs). …”
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Harnessing protein language model for structure-based discovery of highly efficient and robust PET hydrolases by Banghao Wu, Bozitao Zhong, Lirong Zheng, Runye Huang, Shifeng Jiang, Mingchen Li, Liang Hong, Pan Tan

“…X-ray crystallography and molecular dynamics simulations show that KbPETase possesses a conserved catalytic domain and enhanced intramolecular interactions, underpinning its improved functionality and thermostability. …”
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Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites by Lucía Amado, Louis Percifull, Rico Franzkoch, Vico Flatemersch, Eleni Joana Brüggemann, Olympia Ekaterini Psathaki, Maya Schuldiner, Maria Bohnert, Margret H. Bülow, Ayelén González Montoro

“…Abstract Peroxisomes are ubiquitous organelles that mediate central metabolic functions, such as fatty acid β-oxidation, as well as diverse tissue- and organism-specific processes. …”
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Nerve growth factor: what can surgeons and oncologists learn from a neurological and psychological biomarker? by Fei Xiong, Ben-li Xiao, Qi Wang, Kun Liu, Hong-wei Wu, Chao Jing, Kui-nan Tong, Zhong-tao Zhang, Wei Guo

“…Main text This review compares mechanistic insights and therapeutic advancements regarding NGF signalling in neurological/psychological disorders with discoveries in oncological contexts. Functioning as a dual biomarker for neural integrity and pathological progression, NGF primarily exerts its effects via an interaction with the high-affinity tyrosine kinase receptor. …”
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Designs of NKG2D-based immunotherapeutics for cancer by Jianfeng Han, Youwei Wang, Godfrey Chi-Fung Chan, Godfrey Chi-Fung Chan, Wing Keung Chan

“…Despite being genomically conserved between human and mouse, NKG2D transcripts have splice variants that can differentiate the two. hNKG2D or mNKG2D (both long and short transcripts) interacts with DAP10 only in human but DAP10/12 in mouse, switching on different effector functions such as IFN-γ production and cytotoxicity. …”
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Femoral Neck Fractures in Elderly Patients: Dual Mobility Cup Arthroplasty or Hemiarthroplasty? A Narrative Review of the Literature by Calogero Cicio, Gianluca Testa, Giancarlo Salvo, Benedetta Liguori, Andrea Vescio, Vito Pavone, Marco Sapienza

“…While hemiarthroplasty has long been the standard treatment, total hip arthroplasty (THA) is increasingly favored for more active or functionally demanding patients. Among the surgical options, dual mobility THA (DM-THA) stands out for its potential to significantly reduce postoperative complications, particularly dislocations, when compared to both conventional THA and hemiarthroplasty. …”
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Genome-wide identification, characterization and expression pattern analysis of the VDAC gene family reveals likely roles in rapid shoot growth and abiotic stress in Moso bamboo ((... by Zhen Yu, Sijia Cai, Xueyun Xuan, Shiying Su, Jiaqi Tan, Zhijun Zhang

“…This study provides a theoretical basis for exploring the functions of VDACs in bamboo plants and screening candidate genes related to rapid growth and stress tolerance.…”
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A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A by Ibrahim M. Sabbarini, Dvir Reif, Kibum Park, Alexander J. McQuown, Anjali R. Nelliat, Charlotte Trejtnar, Volker Dötsch, Eugene I. Shakhnovich, Andrew W. Murray, Vladimir Denic

“…Proteomics and biochemical reconstitution reveal that Ypl225w functions as a co-translational chaperone by forming dual interactions with the eEF1A G domain nascent chain and the UBA domain of ribosome-bound nascent polypeptide-associated complex (NAC). …”
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Springtail diversity in South Africa by Charlene Janion, Anne Bedos, Jan Bengtsson, Louis Deharveng, Bettine Jansen van Vuuren, Hans Petter Leinaas, Amy Liu, Anna Malmström, David Porco, Steven Chown

“…Despite their significance in soil ecosystems and their use for investigations of soil ecosystem functioning and in bioindication elsewhere, springtails (Collembola) have not been well investigated in South Africa. …”
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Nuclear basket nucleoporin MoNup50 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae by Ying-Ying Cai, Xue-Ming Zhu, Muhammad Noman, Jing Wang, Zhong-Na Hao, Yan-Li Wang, Lin Li, Xiao-Hong Liu, Jian-Ping Lu, Jiao-Yu Wang, Fu-Cheng Lin

“…In this study, we functionally characterized MoNup50, a nuclear pore-associated protein. …”
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Exploring the influence of natural features on soil mesofaunal communities in agricultural landscapes through DNA metabarcoding by Angeli Sahdra, Angeli Sahdra, Monica R. Young, Lori A. Phillips, Niloofar Alavi, David R. Lapen, Jeremy T. Kerr, Marla D. Schwarzfeld

“…Agricultural activities can physically and chemically influence soil mesofauna communities, thereby impacting the ecosystem services they provide. Conserving natural features in agricultural environments is well known to support biodiversity and associated ecosystem services, yet soil mesofauna communities and their functions in such features require further study. …”
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Molecular Insights into the Role of the MET30 Protein and Its WD40 Domain in <i>Colletotrichum gloeosporioides</i> Growth and Virulence by Fei Wu, Qianlong Sun, Longhui Huang, Sizhen Liu, Yue Chen, Xin Zhang, Chenggang Li, Sheng Guo, Xinqiu Tan

“…In this study, we focused on the MET30 protein and its key WD40 domain, with an emphasis on its role in the biological functions of <i>C. gloeosporioides</i>. Bioinformatics analysis revealed that the MET30 protein contains a conserved F-box domain and multiple WD40 repeats, which interact with other proteins to participate in various cellular processes, including nutrient acquisition, stress responses, and pathogenicity. …”
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The Female Athlete Triad: A Metabolic Phenomenon by Anne B. Loucks

“…Energy availability is the amount of dietary energy remaining after exercise training for all other physiological functions each day.  The specific kind of reproductive dysfunctions caused by low energy availability are functional hypothalamic menstrual disorders.  …”
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Phylogenetic Relationships of Three Ramaria Species Based on Mitochondrial Genome Analysis by Xianyi Wang, Zhongyao Guo, Jiawei Tao, Gongyou Zhang, Guoyu Wang, Yaping Wang, Yaohang Long, Hongmei Liu

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Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins by Madushi Wanaguru, Kate N. Bishop

“…The p12 protein has N- and C-terminal domains (NTD and CTD) that are required for steps leading up to integration, but the molecular details of their functions remain poorly characterised. Using the prototypic gammaretrovirus, murine leukemia virus (MLV) as a model, we recently showed that the NTD of p12 directly binds to and stabilises the capsid (CA) lattice of the viral core. …”
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Recruitment of Polo kinase to the spindle midzone during cytokinesis requires the Feo/Klp3A complex. by Pier Paolo D'Avino, Vincent Archambault, Marcin R Przewloka, Wei Zhang, Kathryn S Lilley, Ernest Laue, David M Glover

“…Their roles during cytokinesis, however, are not well understood because the requirement of these kinases during early stages of mitosis complicates the study of their functions after anaphase onset.<h4>Methodology/principal findings</h4>We used time-lapse microscopy to analyze the dynamics of Polo::GFP in Drosophila tissue culture cells during mitosis. …”
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Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. by Hemant Bengani, Shweta Mendiratta, Jayant Maini, Dasari Vasanthi, Hina Sultana, Mohsen Ghasemi, Jasmine Ahluwalia, Sowmya Ramachandran, Rakesh K Mishra, Vani Brahmachari

“…Taken together, our results strongly suggest that PRE-PIK3C2B functions as a site of interaction for polycomb proteins.…”
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Development and Notch signaling requirements of the zebrafish choroid plexus. by Brent R Bill, Darius Balciunas, Joshua A McCarra, Eric D Young, Toua Xiong, Ashley M Spahn, Marta Garcia-Lecea, Vladimir Korzh, Stephen C Ekker, Lisa A Schimmenti

“…The CP has two primary functions, 1) to produce and regulate components of the cerebral spinal fluid, and 2) to inhibit entry into the brain of exogenous substances. …”
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