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  1. 6401

    Metallothionein as an Anti-Inflammatory Mediator by Ken-ichiro Inoue, Hirohisa Takano, Akinori Shimada, Masahiko Satoh

    Published 2009-01-01
    “…The integration of knowledge concerning the regulation of MT, a highly conserved, low molecular weight, cystein-rich metalloprotein, on its proposed functions is necessary to clarify how MT affects cellular processes. …”
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    Article
  2. 6402

    The 40S ribosomal protein SA-2 inhibits citrus yellow vein clearing virus infection in Eureka lemon via activating jasmonic acid and photosynthetic pathways by Ping Liao, Mengyang Huangfu, Dongdong Ding, Xue Dan, Li Chen, Binghai Lou, Yan Zhou

    Published 2025-02-01
    “…Abstract The 40S ribosomal protein SA (RPSA) functions as an important regulatory factor in plant resistance to abiotic stresses. …”
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    Article
  3. 6403

    The immunopeptidome of colon cancer cells treated with topoisomerase inhibiting drug reveals differential as well as common endogenous protein sampling and display of MHC I-associa... by Deepa Bedi, Mohammed Hassan, Alehegne Yirsaw, Biba Vikas, Pran Datta, Temesgen Samuel

    Published 2025-12-01
    “…Additionally, clustering analysis revealed a set of peptides with uniquely conserved residues displayed only in treated MSS SW620 cells. …”
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  4. 6404

    NF-κB signaling driven by oncogenic Ras contributes to tumorigenesis in a Drosophila carcinoma model. by Caroline Dillard, José Teles-Reis, Ashish Jain, Marina Gonçalves Antunes, Paula Ruiz-Duran, Yanyan Qi, Roland Le Borgne, Heinrich Jasper, Tor Erik Rusten

    Published 2025-04-01
    “…Using a well-studied cooperative RasV12-driven epithelial-derived tumor model, we here describe functions of Toll-NF-κB signaling in malignant RasV12, scrib- tumors. …”
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    Article
  5. 6405

    Genome-wide analysis of human disease alleles reveals that their locations are correlated in paralogous proteins. by Mark Yandell, Barry Moore, Fidel Salas, Chris Mungall, Andrew MacBride, Charles White, Martin G Reese

    Published 2008-11-01
    “…The millions of mutations and polymorphisms that occur in human populations are potential predictors of disease, of our reactions to drugs, of predisposition to microbial infections, and of age-related conditions such as impaired brain and cardiovascular functions. However, predicting the phenotypic consequences and eventual clinical significance of a sequence variant is not an easy task. …”
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    Article
  6. 6406

    DDX21 Is a Potential Biomarker for Predicting Recurrence and Prognosis in Hepatocellular Carcinoma by Chengjie Ji, Qing Zhong, Huilan Su, Xiaoli Xue, Renxiang Yang, Na Li

    Published 2025-01-01
    “…DEAD-box helicase 21 (DDX21) is a conserved Asp-Glu-Ala-Asp (DEAD) box RNA helicase with multiple functions that is involved in various cellular processes and diseases. …”
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    Article
  7. 6407

    Prioritizing urban diplomacy policy in Mashhad; From goal setting to policy making by hossein mehrabanifar, Edris Ramooz

    Published 2023-11-01
    “…Among the cities of Iran, Mashhad, with its cultural-religious background and distinct geographical location, has multiple functions and opportunities in urban diplomacy, which makes it necessary to have targeted urban policy making in this region. …”
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    Article
  8. 6408

    The Role Played by Folklore in Raising up an African Child by Nontokozo Gladys Mdhluli

    Published 2025-06-01
    “…This study adds to the body of knowledge by demonstrating the diverse functions of folklore in society, not only as a holdover from the past, but as a dynamic, ever-evolving mode of cultural expression that still shapes ethics, behaviour, and identity formation.…”
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  9. 6409

    A Chronological Review of the Expansion of the Museum’s Role in Relation to Spatial Changes by Jun-Young Heo, Jae Hong Lee

    Published 2025-06-01
    “…Then, the spatial changes were categorized regarding functions and characteristics. Through an in-depth investigation of a literature review and case studies, the findings suggest that museums had been understood as a place for collecting, exhibiting, and enjoying materials. …”
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    Article
  10. 6410

    Genome-Wide Identification of <i>G3BP</i> Family in U’s Triangle <i>Brassica</i> Species and Analysis of Its Expression in <i>B. napus</i> by Alain Tseke Inkabanga, Qiheng Zhang, Shanshan Wang, Yanni Li, Jingyi Chen, Li Huang, Xiang Li, Zihan Deng, Xiao Yang, Mengxin Luo, Lingxia Peng, Keran Ren, Yourong Chai, Yufei Xue

    Published 2025-07-01
    “…The RasGAP SH3 domain binding protein (G3BP) is a highly conserved family of proteins in eukaryotic organisms that coordinates signal transduction and post-transcriptional gene regulation and functions in the formation of stress granules. …”
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    Article
  11. 6411

    Identification of the Cinnamyl Alcohol Dehydrogenase Gene Family in <i>Brassica</i> U-Triangle Species and Its Potential Roles in Response to Abiotic Stress and Regulation of Seed... by Yiwei Liu, Ziwuyun Weng, Yuanyuan Liu, Mengjiao Tian, Yaping Yang, Nian Pan, Mengzhen Zhang, Huiyan Zhao, Hai Du, Nengwen Yin, Cunmin Qu, Huafang Wan

    Published 2025-04-01
    “…Cinnamyl alcohol dehydrogenase (CAD) is essential for lignin precursor synthesis and responses to various abiotic stresses in plants. However, the functions of CAD in <i>Brassica</i> species, especially in <i>Brassica napus</i>, remain poorly characterized. …”
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    Article
  12. 6412

    Multi-fold increase in rainforest tipping risk beyond 1.5–2&thinsp;°C warming by C. Singh, C. Singh, C. Singh, R. van der Ent, I. Fetzer, I. Fetzer, I. Fetzer, L. Wang-Erlandsson, L. Wang-Erlandsson, L. Wang-Erlandsson

    Published 2024-12-01
    “…When this root zone soil moisture is inadequate to sustain a forest ecosystem, they transition to a savanna-like state, losing their native structure and functions. Yet the influence of climate change on ecosystem's root zone soil moisture storage and the impact on rainforest ecosystems remain uncertain. …”
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    Article
  13. 6413

    Adrenal mass: Unusual presentation and outcome by Raghu Sampally Ramareddy, Anand Alladi

    Published 2017-01-01
    “…Aim: Adrenal mass may be functioning or nonfunctioning with varied clinical presentations. …”
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  14. 6414

    Altering mammalian transcription networking with ADAADi: An inhibitor of ATP-dependent chromatin remodeling. by Radhakrishnan Rakesh, Upasana Bedi Chanana, Saddam Hussain, Soni Sharma, Kaveri Goel, Deepa Bisht, Ketki Patne, Pynskhem Bok Swer, Joel W Hockensmith, Rohini Muthuswami

    Published 2021-01-01
    “…Using HeLa and DU145 cells as model system we have explored the effect of ADAADi on cellular functions. We show that the transcriptional network of a cell type is altered when treated with sub-lethal concentration of ADAADi. …”
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    Article
  15. 6415

    Complex Analysis of the Sustainability of the Organization: Methodology and Technology of Standardization by Elena B. Gerasimova

    Published 2018-04-01
    “…In a stagnant national economy for enterprises and organizations becomes important to conserve resources, increase efficiency. One of the ways of increasing quality of activity of the economic entity is the streamlining (standardization) of the analytical procedures. …”
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  16. 6416

    Clinical Outcomes After Standard Discectomy and Microdiscectomy for Lumbar Disc Herniation: A Single-Center Study by Mladen Ovcharov

    Published 2020-09-01
    “…In most cases, surgery quickly relieves pain symptoms, all along with the restoration of patient functions. The optimal surgical technique for LDH is theoretically controversial. …”
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  17. 6417

    Mover is a homomeric phospho-protein present on synaptic vesicles. by Saheeb Ahmed, Nina Wittenmayer, Thomas Kremer, Jan Hoeber, Asha Kiran Akula, Henning Urlaub, Markus Islinger, Joachim Kirsch, Camin Dean, Thomas Dresbach

    Published 2013-01-01
    “…With remarkably few exceptions, the molecules mediating synaptic vesicle exocytosis at active zones are structurally and functionally conserved between vertebrates and invertebrates. …”
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  18. 6418

    Elevated ambient temperature reduces fat storage through the FoxO-mediated insulin signaling pathway. by Tucker Hopkins, Cole Ragsdale, Jin Seo

    Published 2025-01-01
    “…The Forkhead box O (FoxO) protein functions as a key downstream signaling molecule in this pathway, mediating the inhibitory effects of insulin signaling. …”
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  19. 6419

    Hidden Adler zeros and soft theorems for inflationary perturbations by Zong-Zhe Du

    Published 2025-03-01
    “…Abstract We derive soft theorems for on-shell scattering amplitudes from non-linearly realised global space-time symmetries, arising from the flat space and decoupling limits of the effective field theories (EFTs) of inflation, while taking particular care of on-shell limits, soft limits, time-ordered correlations, momentum derivatives, energy-momentum conserving delta functions and iε prescriptions. Intriguingly, contrary to common belief, we find with a preferred soft hierarchy among the soft momentum q, on-shell residue p a 0 $$ {p}_a^0 $$ ± E a , and ε, the soft theorems do not have dependence on unconstrained off-shell interactions, even in the presence of cubic vertices. …”
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  20. 6420

    Identification of a large anion channel required for digestive vacuole acidification and amino acid export in Plasmodium falciparum. by Gagandeep S Saggu, Jinfeng Shao, Mansoor A Siddiqui, Maria Traver, Tatiane Macedo-Silva, Joseph Brzostowski, Sanjay A Desai

    Published 2025-05-01
    “…We propose that BVAC functions to maintain electroneutrality during H+ uptake, allowing DV acidification and efficient hemoglobin digestion. …”
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