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6401
Metallothionein as an Anti-Inflammatory Mediator
Published 2009-01-01“…The integration of knowledge concerning the regulation of MT, a highly conserved, low molecular weight, cystein-rich metalloprotein, on its proposed functions is necessary to clarify how MT affects cellular processes. …”
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6402
The 40S ribosomal protein SA-2 inhibits citrus yellow vein clearing virus infection in Eureka lemon via activating jasmonic acid and photosynthetic pathways
Published 2025-02-01“…Abstract The 40S ribosomal protein SA (RPSA) functions as an important regulatory factor in plant resistance to abiotic stresses. …”
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6403
The immunopeptidome of colon cancer cells treated with topoisomerase inhibiting drug reveals differential as well as common endogenous protein sampling and display of MHC I-associa...
Published 2025-12-01“…Additionally, clustering analysis revealed a set of peptides with uniquely conserved residues displayed only in treated MSS SW620 cells. …”
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6404
NF-κB signaling driven by oncogenic Ras contributes to tumorigenesis in a Drosophila carcinoma model.
Published 2025-04-01“…Using a well-studied cooperative RasV12-driven epithelial-derived tumor model, we here describe functions of Toll-NF-κB signaling in malignant RasV12, scrib- tumors. …”
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6405
Genome-wide analysis of human disease alleles reveals that their locations are correlated in paralogous proteins.
Published 2008-11-01“…The millions of mutations and polymorphisms that occur in human populations are potential predictors of disease, of our reactions to drugs, of predisposition to microbial infections, and of age-related conditions such as impaired brain and cardiovascular functions. However, predicting the phenotypic consequences and eventual clinical significance of a sequence variant is not an easy task. …”
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6406
DDX21 Is a Potential Biomarker for Predicting Recurrence and Prognosis in Hepatocellular Carcinoma
Published 2025-01-01“…DEAD-box helicase 21 (DDX21) is a conserved Asp-Glu-Ala-Asp (DEAD) box RNA helicase with multiple functions that is involved in various cellular processes and diseases. …”
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6407
Prioritizing urban diplomacy policy in Mashhad; From goal setting to policy making
Published 2023-11-01“…Among the cities of Iran, Mashhad, with its cultural-religious background and distinct geographical location, has multiple functions and opportunities in urban diplomacy, which makes it necessary to have targeted urban policy making in this region. …”
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6408
The Role Played by Folklore in Raising up an African Child
Published 2025-06-01“…This study adds to the body of knowledge by demonstrating the diverse functions of folklore in society, not only as a holdover from the past, but as a dynamic, ever-evolving mode of cultural expression that still shapes ethics, behaviour, and identity formation.…”
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6409
A Chronological Review of the Expansion of the Museum’s Role in Relation to Spatial Changes
Published 2025-06-01“…Then, the spatial changes were categorized regarding functions and characteristics. Through an in-depth investigation of a literature review and case studies, the findings suggest that museums had been understood as a place for collecting, exhibiting, and enjoying materials. …”
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6410
Genome-Wide Identification of <i>G3BP</i> Family in U’s Triangle <i>Brassica</i> Species and Analysis of Its Expression in <i>B. napus</i>
Published 2025-07-01“…The RasGAP SH3 domain binding protein (G3BP) is a highly conserved family of proteins in eukaryotic organisms that coordinates signal transduction and post-transcriptional gene regulation and functions in the formation of stress granules. …”
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6411
Identification of the Cinnamyl Alcohol Dehydrogenase Gene Family in <i>Brassica</i> U-Triangle Species and Its Potential Roles in Response to Abiotic Stress and Regulation of Seed...
Published 2025-04-01“…Cinnamyl alcohol dehydrogenase (CAD) is essential for lignin precursor synthesis and responses to various abiotic stresses in plants. However, the functions of CAD in <i>Brassica</i> species, especially in <i>Brassica napus</i>, remain poorly characterized. …”
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6412
Multi-fold increase in rainforest tipping risk beyond 1.5–2 °C warming
Published 2024-12-01“…When this root zone soil moisture is inadequate to sustain a forest ecosystem, they transition to a savanna-like state, losing their native structure and functions. Yet the influence of climate change on ecosystem's root zone soil moisture storage and the impact on rainforest ecosystems remain uncertain. …”
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6413
Adrenal mass: Unusual presentation and outcome
Published 2017-01-01“…Aim: Adrenal mass may be functioning or nonfunctioning with varied clinical presentations. …”
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6414
Altering mammalian transcription networking with ADAADi: An inhibitor of ATP-dependent chromatin remodeling.
Published 2021-01-01“…Using HeLa and DU145 cells as model system we have explored the effect of ADAADi on cellular functions. We show that the transcriptional network of a cell type is altered when treated with sub-lethal concentration of ADAADi. …”
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6415
Complex Analysis of the Sustainability of the Organization: Methodology and Technology of Standardization
Published 2018-04-01“…In a stagnant national economy for enterprises and organizations becomes important to conserve resources, increase efficiency. One of the ways of increasing quality of activity of the economic entity is the streamlining (standardization) of the analytical procedures. …”
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6416
Clinical Outcomes After Standard Discectomy and Microdiscectomy for Lumbar Disc Herniation: A Single-Center Study
Published 2020-09-01“…In most cases, surgery quickly relieves pain symptoms, all along with the restoration of patient functions. The optimal surgical technique for LDH is theoretically controversial. …”
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6417
Mover is a homomeric phospho-protein present on synaptic vesicles.
Published 2013-01-01“…With remarkably few exceptions, the molecules mediating synaptic vesicle exocytosis at active zones are structurally and functionally conserved between vertebrates and invertebrates. …”
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6418
Elevated ambient temperature reduces fat storage through the FoxO-mediated insulin signaling pathway.
Published 2025-01-01“…The Forkhead box O (FoxO) protein functions as a key downstream signaling molecule in this pathway, mediating the inhibitory effects of insulin signaling. …”
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6419
Hidden Adler zeros and soft theorems for inflationary perturbations
Published 2025-03-01“…Abstract We derive soft theorems for on-shell scattering amplitudes from non-linearly realised global space-time symmetries, arising from the flat space and decoupling limits of the effective field theories (EFTs) of inflation, while taking particular care of on-shell limits, soft limits, time-ordered correlations, momentum derivatives, energy-momentum conserving delta functions and iε prescriptions. Intriguingly, contrary to common belief, we find with a preferred soft hierarchy among the soft momentum q, on-shell residue p a 0 $$ {p}_a^0 $$ ± E a , and ε, the soft theorems do not have dependence on unconstrained off-shell interactions, even in the presence of cubic vertices. …”
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6420
Identification of a large anion channel required for digestive vacuole acidification and amino acid export in Plasmodium falciparum.
Published 2025-05-01“…We propose that BVAC functions to maintain electroneutrality during H+ uptake, allowing DV acidification and efficient hemoglobin digestion. …”
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