Active protein quality control in quiescence: involvement of proteasomes, autophagy, and nucleus-vacuole junctions by Mihaela Pravica, Dina Franić, Mirta Boban

“…Quiescence is a conserved, reversible state of proliferative arrest, characterized by changes in cell physiology and metabolism. …”
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The term cotwin with spatial pulmonary lesions and elevated maternal-neonatal D-dimer levels following single intrauterine fetal death in a monochorionic-monoamniotic twin pregnanc... by Haiyan Liu, Xiaoyue Zhang, Zhenzhen Liu, Yi Yu, Weirong Gu

“…Abstract Background Complications such as cerebral impairment, preterm delivery, and even intrauterine death can occur in monochorionic twin pregnancies with singleton fetal death. The coagulation functions of the surviving fetus and mother remain controversial. …”
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Cost‐effective and simple flow cytometry quantification of receptor‐mediated autophagy using fluorescent tagging by Mija Marinković, Ana Rožić, Denis Polančec, Ivana Novak

“…Mitophagy, a selective clearance of damaged or superfluous mitochondria via autophagy machinery and lysosomal degradation, is an evolutionarily conserved process essential for various physiological functions, including cellular differentiation and immune responses. …”
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Fragments of viral surface proteins modulate innate immune responses via formyl peptide receptors by Heiko Heilmann, Lukas Busch, Celine Buchmann, Islam Mohamed, Adrian Theiß, Sabryna Junker, Stefan Lohse, Bernd Bufe

“…Peptides containing these motifs interact with all FPR family members and modulate various important immune functions in innate immune cells. Viral breakdown products comprising these motifs were found in patients with COVID-19. …”
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Epiploic Appendagitis: An Infrequent Offender in Abdominal Pain by George Sarin Zacharia, Anu Jacob, Mathew Vadukoot, Muhammed Ali

“…Epiploic appendages are fat-filled outpouchings arising from the serosal surface of the colon and have uncertain physiological functions. Epiploic appendagitis is characterized by inflammation of these appendages. …”
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Improved multi-objective decision-making in manufacturing processes through uncertainty quantification and robust pareto front modelling by Arne De Temmerman, Mathias Verbeke

“…We investigate the impact of aleatoric uncertainty on multi-objective optimization, demonstrating enhanced Pareto front creation and improved decision-making under non-linear process functions. The methodology is applied to a continuous manufacturing case, where probabilistic surrogate sampling generates a more conservative setpoint. …”
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Annexin A2 at the Interface of Actin and Membrane Dynamics: A Focus on Its Roles in Endocytosis and Cell Polarization by Adam G. Grieve, Stephen E. Moss, Matthew J. Hayes

“…They are structurally highly conserved and have been implicated in a wide range of cellular activities. …”
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Fha initiates the inside-out assembly of the type VI secretion system by Tong-Tong Pei, Xing-Yu Wang, Yi-Qiu Zhang, Ying An, Han Luo, Yumin Kan, Hao Li, Ming-Xuan Tang, Zi-Yan Ye, Jia-Xin Liang, Tao Jian, Hao-Yu Zheng, Zeng-Hang Wang, Xiaoye Liang, Xiaotian Liu, Mingjie Zhang, Tao Dong

“…The Fha homolog in the human pathogen Pseudomonas aeruginosa exhibits conserved functions in condensate formation. These findings unveil an inside-out model for T6SS assembly primed by an LLPS-mediator, Fha, that is crucial for promoting assembly efficiency.…”
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Mitochondrial genome characterization, evolution and intron dynamics of the entomopathogenic genus Cordyceps by Jinlong Jia, Jinlong Jia, Jinlong Jia, Chengpeng Li, Mei Tang, Mei Tang, Mei Tang, Hefa Liao, Hefa Liao, Hefa Liao, Zhuliang Yang, Zhuliang Yang, Yanan Wang, Ming Li, Wenbo Zeng, Yuanbing Wang, Yuanbing Wang

“…The rps3 gene appears to be under relaxed selection pressure across Cordyceps species. The non-conserved PCGs, such as homing endonucleases and proteins of unknown functions, show dynamic evolutionary patterns, highlighting the genetic diversity among the species. …”
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Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli by Martina Rudgalvyte, Zehan Hu, Dieter Kressler, Jörn Dengjel, Dominique A Glauser

“…Cell-specific manipulations indicate that CMK-1 acts in AFD and ASER thermo-sensory neurons, while TAX-6 functions in FLP thermo-sensory neurons and downstream interneurons. …”
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Variants of the human RAD52 gene confer defects in ionizing radiation resistance and homologous recombination repair in budding yeast by Alissa D. Clear, Glenn M. Manthey, Olivia Lewis, Isabelle Y. Lopez, Rossana Rico, Shannon Owens, M. Cristina Negritto, Elise W. Wolf, Jason Xu, Nikola Kenjić, J. Jefferson P. Perry, Aaron W. Adamson, Susan L. Neuhausen, Adam M. Bailis

“…RAD52 is a structurally and functionally conserved component of the DNA double-strand break (DSB) repair apparatus from budding yeast to humans. …”
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Konflik Sosial dalam Komunitas Virtual di Kalangan Remaja by Dony Arung Triantoro

“…This study found that social conflict in the virtual community of adolescents was caused by misunderstandings in understanding the text or opinions, sensitivity to symbols, time and community functions, cyberbullying, SARA issues and egocentric posts on differences in the background of community members. …”
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The conceptual problem of accounting for the innovation capital of the enterprise: reasons for the emergence by V.K.

“…The limitations of accounting in disclosing information about the innovative activity of the enterprise and its influence on the functioning of other management systems have been revealed. …”
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Application and Discussion of Intelligent Operation and Maintenance of BIM Visualization Platform for Drainage Pumping Stations by PENG Muzhan, ZANG Peiyuan, REN Weixu, GAO Ting, XU Zedian

“…The construction of a BIM visualization platform for the intelligent operation and maintenance of drainage pumping stations is an important part of smart water.It plays a crucial role in improving the project management level,reducing the loss of possible flood disasters,and strengthening the ability of water utilities to deal with risks.However,in the operation and maintenance management of traditional water utilities,the backward management methods and means often result in problems such as high costs,low efficiency,and slow response.Therefore,this paper puts forward a solution to the top-level design of the platform architecture.In view of the current management practice,we realize the functions including BIM model visualization,the unit operation status display,inventory asset management,statistical report query,and personnel management by combining the platform with the emerging technologies in the information field.This study demonstrates a good engineering application for the construction of the intelligent operation and maintenance platform and can be used for reference for the follow-up construction of smart water and the informatization of water conservancy.…”
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Synaptonemal Complex dimerization regulates chromosome alignment and crossover patterning in meiosis. by Spencer G Gordon, Lisa E Kursel, Kewei Xu, Ofer Rog

“…However, the molecular mechanisms by which the SC carries out these functions remain poorly understood. Here we isolated and characterized two mutations in the dimerization interface in the middle of the SC zipper in C. elegans. …”
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Healing of Large Endodontic Lesions Using Long-Term Application of a New Combination of Triple Antibiotics: A Series of Cases by Saeed Asgary, Ardavan Parhizkar

“…Additionally, complete functionality of the involved teeth as well as other favourable treatment outcomes of the addressed cases showed that the long-term use of PMC, as a modified combination of antibiotics, in non-surgical endodontic retreatments may successfully resolve large AP. …”
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Du sol foncier au sol vivant by Atelier Georges, Thibault Barbier, Mathieu Delorme, Charles Rives

“…The soil as a vaguely characterised two-dimensional surface which currently conditions the transformation of territories takes on essential ecological functions thus challenging our system of values and societal aspirations. …”
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Platforms, Personalism, and Propaganda: The Digital Investment of the Far Right in Brazil and the Reconfiguration of Political Mediation by Mércia Freitas Alves

“…It argues that this digital ecosystem functions as a «parallel party»,combining sophisticated campaign technologies with informal and unregulated practices. …”
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Modulation of epithelial homeostasis by HPV using Notch and Wnt by June See Chong, John Doorbar

“…Highly conserved signalling pathways such as Notch and Wnt are essential in the regulation of differentiation and proliferation processes during adult tissue homeostasis. …”
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An ER complex of ODR-4 and ODR-8/Ufm1 specific protease 2 promotes GPCR maturation by a Ufm1-independent mechanism. by Changchun Chen, Eisuke Itakura, Katherine P Weber, Ramanujan S Hegde, Mario de Bono

“…Thus, UfSP2 proteins have protease- and Ufm1-independent functions in GPCR biogenesis.…”
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