Natural variation of ClCCT promoter promotes flowering and dwarfing in adlay (Coix lacryma-jobi L.) by Jieliang Bao, Yanan Wang, Kuoshu Cui, Xiangdong Li, Hong Pan, Chaoyuan Shi, Xiang Yan, Jinglin Wang, Xiaotong Wang, Qing Dou, Xiaolong Dong, Yibing Yuan, Shufeng Zhou, Chao Guo

“…In this study, a major QTL associated with flowering time and plant height in adlay has been mapped and identified as ClCCT, a gene having a conserved function and regulatory pathway for inhibiting flowering time and increasing plant height in gramineous crops. …”
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Analysis of genomic ancestry and characterization of a new variant in MPS type VII by Andreza Juliana Moreira da Costa, Isabel Cristina Neves de Souza, Raimunda Helena Feio, Laurent Ketlen Leão Viana, Mislene Cisz, Célio Luiz Rafaelli, Franciele Barbosa Trapp, Maira Graeff Burin, Kristiane Michelin-Tirelli, Ana Carolina Brusius-Facchin, Alice Brinckmann Oliveira Netto, André Salim Khayat, Ney Pereira Carneiro dos Santos, Roberto Giugliani, Luiz Carlos Santana-da-Silva

“…The in silico prediction of the new variant indicated that it affects function by modifying a highly conserved region. Conclusions The p.Leu176Phe mutation may have originated in Europe, as suggested in this study. …”
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Impacts of human footprint on habitat quality and permafrost environment in Northeast China by Jianjun Tang, Xiaoying Jin, Haowei Mu, Sizhong Yang, Ruixia He, Xiaoying Li, Wenhui Wang, Shuai Huang, Jiaxing Zu, Hongwei Wang, Zuwang Li, Lin Yang, Shanzhen Li, Yanlin Shi, Suiqiao Yang, Raul-D. Serban, Mihaela Șerban, Alexander Fedorov, Leonid Gagarin, Ze Zhang, Mikhail N Zhelezniak, Huijun Jin

“…In Northeast China, intensified human footprints have greatly altered ecosystem service functions, leading to biodiversity decline, habitat fragmentation, and permafrost warming and thaw. …”
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Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence by Dana S. Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P. Whitelegge, Z. Hong Zhou, Andreas Tauch, Asis Das, Hung Ton-That

“…Here we investigated the molecular assembly, regulation, and function of BMCs in Fusobacterium nucleatum—a Gram-negative oral pathobiont that is associated with adverse pregnancy outcomes. …”
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LRP6 regulates growth in Litopenaeus vannamei via the Wnt/β-catenin signaling pathway by Sheng Wang, Xiaodi Wang, Hao Yang, Xuanzheng Di, Haoyang Li, Bin Yin, Ziwei Liu, Chaozheng Li, Jianguo He

“…Functional investigations via RNAi technology revealed that silencing LvLRP6 via dsRNA injection resulted in a significant reduction in shrimp growth, as indicated by lower weight gain than that in the control group. …”
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Exploring the mutational spectrum of key kinase genes PIK3CA, BRAF, EGFR, ALK and ROS1 in oral squamous cell carcinoma by Fouzia Nawab, Wafa Naeem, Sadia Fatima, Asif Ali, Ali Talha Khalil, Aamir Mehmood, Muhammad Fazeel, Hilal Ahmad, Mohammed Alorini, Muslim Khan, Ishtiaq Ahmad Khan, Muhammad Irfan, Syed Ali Khurram

“…., ROS1 p.N2240K (score 9) and ROS1 p.L567V (score 8), as highly conserved, likely disrupting kinase function and stability, unlike variable mutations with milder effects. …”
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Correlation between aboveground vegetation composition and soil seed bank of Raudhat desert habitat: a case study of Raudhat Alkhafs, Saudi Arabia by Asma A. Al-Huqail, Hanan F. Al-Harbi, Abdullah M. Alowaifeer, Mohamed A. El-Sheikh, Abdulaziz M. Assaeed, Turki S. Alsaleem, Hazem S. Kassem, Omar M. Azab, Basharat A. Dar, Jahangir A. Malik, Ahmed M. Abd-ElGawad

“…Abstract Plant diversity in arid environments is very important for ecosystem function and services. Raudhat habitat is among the most important ecosystems in the arid regions which is characterized by its rich biodiversity and specific environmental conditions. …”
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Candidate Dark Galaxy-2: Validation and Analysis of an Almost Dark Galaxy in the Perseus Cluster by Dayi (David) Li, Qing Liu, Gwendolyn M. Eadie, Roberto G. Abraham, Francine R. Marleau, William E. Harris, Pieter van Dokkum, Aaron J. Romanowsky, Shany Danieli, Patrick E. Brown, Alex Stringer

“…This ratio is likely to be much higher (∼33%) if CDG-2 has a canonical GC luminosity function (GCLF). In addition, if the previously observed GC-to-halo mass relations apply to CDG-2, it would have a minimum dark matter halo mass fraction of 99.94% to 99.98%. …”
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KDM6A facilitates Xist upregulation at the onset of X inactivation by Josephine Lin, Jinli Zhang, Li Ma, He Fang, Rui Ma, Camille Groneck, Galina N. Filippova, Xinxian Deng, Chizuru Kinoshita, Jessica E. Young, Wenxiu Ma, Christine M. Disteche, Joel B. Berletch

“…A subset of X-linked genes escape silencing and thus have higher expression in females, suggesting female-specific functions. One of these genes is the highly conserved gene Kdm6a, which encodes a histone demethylase that removes methyl groups at H3K27 to facilitate gene expression. …”
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Analysis of the SIRT Gene Family of Danio rerio and Its Expression at Different Developmental Stages of Follicles by Jiabao PENG, Ziyan WANG, Zhigang YANG, Aqin CHEN

“…Among the 10 motifs, motif 2, motif 3, and motif 5 were found in all zebrafish SIRT amino acid sequences, indicating that these protein motifs are highly conserved during development. Conserved domain analysis showed that all SIRT1-7 proteins contained the Sir2 domain. …”
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Dental and oral health assessments in the German National Cohort (NAKO) by Stefanie Samietz, Katrin Borof, Katrin Hertrampf, Ghazal Aarabi, Antonio Ciardo, Hannah Finke, Daniel Hagenfeld, Jan Kühnisch, Maurice Rütters, Sebastian-Edgar Baumeister, Stefan Lars Reckelkamm, Ti-Sun Kim, Thomas Kocher, Wolfgang Ahrens, Hermann Brenner, Carina Emmel, Beate Fischer, Amand Führer, Karin Halina Greiser, Jasmin Grischke, Kathrin Günther, Volker Harth, Stefanie Jaskulski, André Karch, Thomas Keil, Yvonne Kemmling, Alexander Kluttig, Lilian Krist, Oliver Kuss, Michael Leitzmann, Claudia Meinke-Franze, Karin B. Michels, Nadia Obi, Anette Peters, Nicole Pischon, Tobias Pischon, Sabine Schipf, Börge Schmidt, Henning Teismann, Stefan Rupf, Birte Holtfreter

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iMeta Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health by Yao Wang, Huiyu Hou, Hao Luo, Jiani Xun, Chuang Ma, Haifei Yang, Defeng Bai, Salsabeel Yousuf, Hujie Lyu, Tianyuan Zhang, Xiulin Wan, Xiaofang Yao, Tengfei Ma, Yuanping Zhou, Zhihao Zhu, Meiyin Zeng, Sanqi An, Qing Bai, Yao Bai, Guodong Cao, Tingting Cao, Yongkai Cao, Chihmin Chang, Lijia Chang, Bo Chen, Dai Chen, Dijun Chen, Hanqing Chen, Jiali Chen, Jinfeng Chen, Wei‐Hua Chen, Xinhai Chen, Yue Chen, Zhangran Chen, Cheng Cheng, Quan Cheng, Xi‐Jian Dai, Chaowen Deng, Feilong Deng, Jingwen Deng, Chang‐Sheng Dong, Lei Dong, Lianhui Duan, Yi Duan, Qingjie Fan, Chao Fang, Tingyu Fang, Wensheng Fang, Zhencheng Fang, Min Fu, Minjie Fu, Cong Gao, Hao Gao, Weiwei Gao, Xinrui Gao, Yi‐Zhou Gao, Yan Geng, Wenping Gong, Shaohua Gu, Xia Gu, Zhengquan Gu, Jian‐Wei Guo, Junjie Guo, Qiuyan Guo, Xiang Guo, Xiaoqian Guo, Dongfei Han, Ziyi Han, Yanan Hao, Jiale He, Jianquan He, Jianyu He, Ruolin He, Guosen Hou, Bin Hu, Haibo Hu, Yi Hu, Yongfei Hu, Yucan Hu, Guanyin Huang, Haiyun Huang, Jiaomei Huang, Shenghui Huang, Baolei Jia, Xingxing Jian, Chao Jiang, Kun Jiang, Lanyan Jiang, Shuaiming Jiang, Jian‐Yu Jiao, Hao Jin, Jiajia Jin, Siyuan Kong, Xinxing Lai, Yuxin Leng, Bang Li, Bing Li, Fang Li, Hao Li, Huanjie Li, Jing Li, Kai Li, Lanqi Li, Leyuan Li, Minghan Li, Pengsong Li, Wei Li, Wei Li, Xianyu Li, Li Xuemeng, Yafei Li, Yuantao Li, Zhi Li, Liqin Liang, Rong Liang, Zhuobin Liang, Qingya Liu, Dejian Liu, Huiheng Liu, Jinchao Liu, Li Liu, Lihui Liu, Moyang Liu, Ran Liu, Shuai Liu, Tianyang Liu, Wei Liu, Wenjuan Liu, Xiaomin Liu, Yang Liu, Yichen Liu, Yina Liu, Yuan Liu, Zhe Liu, Zhipeng Liu, Zhiquan Liu, Chunhao Long, Yun Long, Changying Lu, Chao Lu, Cheng Lu, Qi Lu, Yaning Luan, Peng Luo, Sheng Luo, Ning Ma, Xiao‐Ya Ma, Yan Ma, Wenjun Mao, Yuanfa Meng, Yan Ni, Yawen Ni, Kang Ning, Dongze Niu, Kai Peng, Zhengwu Peng, Xubo Qian, Zhiguang Qiu, Hui Qu, Zepeng Qu, Yan Ren, Zhigang Ren, Youming Shen, Lin Shi, Linlin Shi, Wenxuan Shi, Yongpeng Shi, Tianyuan Song, Xiaohui Song, Xiaoming Song, Xiaowei Song, Qi Su, Yufan Su, Lifang Sun, Qiang Sun, Tiefeng Sun, Yunke Sun, Hua Tang, Wenjing Tang, Tao Yu, Simon Tian, Shuo Wang, Bowen Wang, Cheng Wang, Wang Jin, Leli Wang, Liangliang Wang, Lixiao Wang, Mingbang Wang, Ming‐Ke Wang, Pingyi Wang, Shaolin Wang, Shaopu Wang, Xinxia Wang, Xueqiang Wang, Mi Wei, Yan Wei, Yanxia Wei, Yongjun Wei, Chaoliang Wen, Xin Wen, Linkun Wu, Shengru Wu, Yuting Wu, Shuting Xia, Xiaodong Xia, Yu Xia, Xionggen Xiang, Chuanxing Xiao, Weihua Xiao, Yingping Xiao, Ruohan Xie, Rui Xing, Hui Xu, Wei Xu, Zhimin Xu, Hongliang Xue, Chao Yan, Qiu‐Long Yan, Shaofei Yan, Xiuchuan Yan, Mengli Yang, Yufan Yang, Zhipeng Yang, Ziyuan Yang, Guixiang Yao, Yanlai Yao, Xianfu Yi, Chong Yin, Mingliang Yin, Shicheng Yu, Ying Yu, Yongyao Yu, Fusong Yuan, Shao‐Lun Zhai, Bo Zhang, Chen Zhang, Fang Zhang, Feng‐Li Zhang, Hengguo Zhang, Jinping Zhang, Junya Zhang, Kun Zhang, Li Zhang, Lin Zhang, Lingxuan Zhang, Meng Zhang, Qian Zhang, Runan Zhang, Tongtong Zhang, Tongxue Zhang, Weipeng Zhang, Yong Zhang, Yuchao Zhang, Yujun Zhang, Zeng Zhang, Zhengxiao Zhang, Zhi‐Feng Zhang, Boxi Zhao, Yanyan Zhao, Yibing Zhao, Ziwei Zhao, Diwei Zheng, Ying Zheng, Wenqiang Zhi, Jixin Zhong, Xiangjian Zhong, Wei Zhou, Xin Zhou, Zhemin Zhou, Zhichao Zhou, Congmin Zhu, Feiying Zhu, Xiaodie Zhu, Yutian Zou, Hongling Zhou, Lei Lei, Yanliang Bi, Hubing Shi, Hui‐Zeng Sun, Shuangxia Jin, Wenkai Ren, Lei Dai, Xin Wang, Canhui Lan, Hongwei Liu, Shuang‐Jiang Liu, Yulong Yin, Chun‐Lin Shi, Ren‐You Gan, Fangqing Zhao, Jun Yu, Tong Chen, Xin Hong, Hua Yang, Bangzhou Zhang, Shifu Chen, Xiaodong Li, Yunyun Gao, Yong‐Xin Liu

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HMGB1 in Septic Muscle Atrophy: Roles and Therapeutic Potential for Muscle Atrophy and Regeneration by Si‐Yuan Qi, Qiqi Wu, Peng‐Hui Xiang, Chao‐Yao Hou, Zhaofeng Kang, Meng‐Qi Chen, Chengla Yi, Xiangjun Bai, Tianyu Li, Zhanfei Li, Wei‐Ming Xie

“…These findings suggest that HMGB1 inhibition could be a viable therapeutic approach for septic myopathy. However, the function of promoting muscle regeneration in septic myopathy needs further research. …”
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Els discent assegut by Juan A. Canal

“…However, the school cannot ignore the structural and functional transformations that the social reality imposes, including the growing importance of ergonomics and its influence on the school in which the child spends a large part of his early years: in line with this idea, here we briefly recount a project undertaken in the “Vega del Prado” Secondary School in Valladolid in order to give an ergonomically appropriate response to the new biotypical needs of schoolchildren in the XXI century, whose backs should always be taken into consideration even though schools continue to insist in their task of educating seated scholars.…”
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ANALYSIS OF THE GINGIVAL RECESSION PREVALENCE AMONG DENTAL PATIENTS CONSIDERING ASSOCIATED AGE-RELATED, IATROGENIC AND PATHOLOGICAL CHANGES OF DENTAL STATUS by O.A. Krasnokutskyy, P.A. Hasiuk, M.Y. Goncharuk-Khomyn

“…Implementation of preventive measure among such risk groups could potentially optimize the prognosis of future conservative or surgical treatment of gingival recessions. …”
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High-Throughput Indirect Monitoring of TORC1 Activation Using the pTOMAN-G Plasmid in Yeast by Melissa Gómez, Guilherme Rocha, Diego Ruiz, Claudio Martínez, Francisco Salinas, Eduardo Kessi-Pérez

“…The target of rapamycin complex 1 (TORC1) is a highly conserved protein complex whose primary function is to link nutrient availability to cell growth in eukaryotes, particularly nitrogen sources. …”
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Improvement of the approach to definition of patient release criteria after radionuclide therapy by L. A. Chipiga, I. A. Zvonova, A. V. Vodovatov, A. V. Petryakova, A. A. Stanzhevsky, D. A. Vazhenina, M. A. Smoliarchuk, S. A. Ryzhov

“…Considering the fast-eliminated fraction in the first hours after the administration, it can be assumed that more patients with normal renal function can undergo radionuclide therapy with 177Lu-PSMA in the outpatient hospital. …”
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Advantages, disadvantages and optimization of organ-sparing methods for uterine fibroids treatment by A. L. Tikhomirov, V. V. Kazenashev, O. V. Maksimova, M. V. Maminova, N. L. Davydenko, N. V. Rurua, T. A. Sonina

“…In both groups, after assessing liver function tests in accordance with the instructions, a treatment course with SPRM group drug (ulipristal acetate) was used at a daily dose of 5 mg for 84 days (one course) with an interval until the onset of second menstruation after drug withdrawal. …”
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Synovial cesys in children: clinical features, diagnostics, treatment (analytical review of the literature and own observation) by V.S. Konoplitskyi, Yu. Ye. Korobko, B.L. Pavlenko, H.M. Rudenko, O.A. Korobko, S.V. Klymenko

“…However, the frequency of hygromas may actually be much higher, due to a certain underestimation of cases when the presence of pathology was not accompanied by impaired function and pain. The etiology of hygromas in children is multifactorial and includes both congenital and acquired factors. …”
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Genomic Survey, Characterization, and Expression Profile Analysis of the SBP Genes in Pineapple (Ananas comosus L.) by Hina Ali, Yanhui Liu, Syed Muhammad Azam, Zia ur Rahman, S. V. G. N. Priyadarshani, Weimin Li, Xinyu Huang, Bingyan Hu, Junjie Xiong, Umair Ali, Yuan Qin

“…Our study lays a foundation for further gene function and expression studies of SBP genes in pineapple.…”
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