Clinical outcomes over 2 years following arthroscopic ankle lateral ligament repair with os subfibulare by Shohei Sano, Noriyuki Kanzaki, Kiminari Kataoka, Koji Nukuto, Tetsuya Yamamoto, Yuta Nakanishi, Kyohei Nishida, Kanto Nagai, Yuichi Hoshino, Takehiko Matsushita, Ryosuke Kuroda

“…The mean scores for pain and related symptoms, foot function and activities of daily living, social functioning, shoe-related, and general health and well-being subscales of the SAFE-Q also showed significant improvements in both groups. …”
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GCN5 Is a Master Regulator of Gene Expression in the Malaria Parasite <i>Plasmodium falciparum</i> by Amuza Byaruhanga Lucky, Ahmad Rushdi Shakri, Xiaoying Liang, Hui Min, Xiao-Lian Li, Swamy Rakesh Adapa, Rays H. Y. Jiang, Liwang Cui, Chengqi Wang, Jun Miao

“…To directly test the PfGCN5 function, we performed conditional knockdown (KD) of <i>PfGCN5</i>. …”
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Evolutionary Analysis of Structural Protein Gene VP1 of Foot-and-Mouth Disease Virus Serotype Asia 1 by Qingxun Zhang, Xinsheng Liu, Yuzhen Fang, Li Pan, Jianliang Lv, Zhongwang Zhang, Peng Zhou, Yaozhong Ding, Haotai Chen, Junjun Shao, Furong Zhao, Tong Lin, Huiyun Chang, Jie Zhang, Yonglu Wang, Yongguang Zhang

“…The remaining sites were not located in known functional regions and were moderately conserved, and the reason for supporting all sites under positive selection remains to be elucidated because the power of these analyses was largely unknown.…”
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Changes in glycinergic neurotransmission alter mammalian retinal information processing by Anneka Joachimsthaler, Anneka Joachimsthaler, Katharina Hauf, Katharina Hauf, Anja Armbruster, Shiri Zayit-Soudry, Efrat Naaman, Ido Perlman, Rina Leibu, Alina Kurolap, Hagit Baris Feldman, Hagit Baris Feldman, Jan Kremers, Jan Kremers, Volker Eulenburg, Volker Eulenburg, Volker Eulenburg

“…To determine if the function of retinal GlyT1 is conserved in humans, we analyzed ERG recordings from a patient diagnosed with GlyT1 encephalopathy. …”
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Targeting EP300 in diffuse large b-cell lymphoma: efficacy of A485 and synergistic effects with XPO1 inhibition by Yanan Jiang, Donghui Xing, Xiang He, Wenqi Wu, Hong Xu, Huimeng Sun, Yixin Zhai, Kaiping Luo, Zhigang Zhao

“…Flow cytometry, colony formation, and western blotting were conducted to investigate the function of EP300. CCK8, proliferation, cell cycle, and apoptosis assays, as well as experiments in tumor-bearing mouse models were conducted to determine the therapeutic effect of the EP300 inhibitor A485 alone or in combination with the XPO1 inhibitor KPT8602. …”
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The efficacy of anterior repositioning splints in the management of temporomandibular disc displacement: a systematic review and meta-analysis by Liujing Wang, Yanni Zhang, Haiyan Chen, Chenxi Jin, Wei Shen, Ziyuan Li, Wei Zhang, Yuxin Shi, Yiyang Hou, Xiaoxuan Li, Jing Guo

“…Conclusion A total of 14 studies were included in this systematic review and meta-analysis, which compared the efficacy of ARS with other conservative treatments for disc displacement. While ARS did not demonstrate a significant difference compared to physical therapy in improving TMJ pain, popping, and mandibular motor function in the initial treatment phase, it exhibited more pronounced effects than physical therapy and behavioral therapy with continued use. …”
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Partner-Inflicted Brain Injury: Intentional, Concurrent, and Repeated Traumatic and Hypoxic Neurologic Insults by Julianna M. Nemeth, Clarice Decker, Rachel Ramirez, Luke Montgomery, Alice Hinton, Sharefa Duhaney, Raya Smith, Allison Glasser, Abigail (Abby) Bowman, Emily Kulow, Amy Wermert

“…Survivor behavior was then interpreted by staff as a “can’t” not a “won’t”, and social and functional supports were offered.…”
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Application of Jane Jacobs’ Theory in the Analysis of the Borders of Territory Monitoring in Urban Spaces from Citizens’ Points of View in Bandar Abbas by Amirhamzeh Shahbazi, Esmaeil zakerimnabi, Alireza Shahbazi

“…The study sought to identify and analyze the mental boundaries and functional areas of monitoring that manifested in citizens' behavioral patterns. …”
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Localization and expression of C1QTNF6 in chicken follicles and its regulatory effect on follicular granulosa cells by Chong Li, Qi Li, Xing Wu, Zihao Zhang, Jing Li, Ruirui Jiang, Guoxi Li, Xiaojun Liu, Xiangtao Kang, Zhuanjian Li, Donghua Li, Yadong Tian

“…However, its expression and function in chickens remain unclear. In this study, the full-length coding sequence (CDS) of chicken C1QTNF6 was cloned from adult chicken ovary. …”
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Characterization of full-length long noncoding RNAs and identification of virus-responsive lncRNAs in Sogatella furcifera by Yawen Ban, Yawen Ban, Ting Cui, Ting Cui, Lifei Zhao, Lifei Zhao, Xue Li, Xue Li, Qing Bai, Qing Bai, Qingfa Wu, Qingfa Wu

“…., 16 in pre-ecdysis), while sex-biased expression patterns emerged after 24 h. Functional enrichment analysis linked male-biased lncRNAs to metabolic pathways and molting-associated lncRNAs to tissue remodeling processes, including Wnt signaling. …”
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Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…Declines in CTRA gene expression did not vary significantly as a function of recent illness, COVID-19 hospitalization, demographic characteristics, or general medical history. …”
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Identification, characterization, and expression of Oryza sativa tryptophan decarboxylase genes associated with fluroxypyr‐meptyl metabolism by Hao Wen Wang, Xu Zhen Shi, Xiao Yu Zhong, Gan Ai, Yan Hui Wang, Zhi Zhong Zhou, Dan Lu, Xiao Liang Liu, Zhao Jie Chen

“…It is the enzyme involved in the first step of melatonin (MT) biosynthesis and mediates several key functions in abiotic stress tolerance. In Oryza sativa under pesticide‐induced stress, TDC function is unclear. …”
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Impact of Computer-Mediated Versus Face-to-Face Motivational-Type Interviews on Participants’ Language and Subsequent Cannabis Use: Randomized Controlled Trial by Karla D Llanes, Jon Amastae, Paul C Amrhein, Nadra Lisha, Katherina Arteaga, Eugene Lopez, Roberto A Moran, Lawrence D Cohn

“…A negative binomial regression with a log link function was used to probe this relationship after controlling for 2 covariates: gender and Time 1 (baseline assessment) marijuana use. …”
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Morphological evaluation of the fibrin framework in the treatment of dental pulp hyperemia: experimental study by K. D. Kirsh, E. S. Zaporozhskaya-Abramova, A. А. Adamchik, V. А. Ivashchenko, V. V. Tairov, U. A. Dotdaeva, V. M. Starchenko

“…The article is aimed at studying and analyzing the potential of regenerative dentistry, which consists in restoring the function and structure of the dental pulp using innovative technologies. …”
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Differential Adjuvant Activity by Flagellins from <i>Escherichia coli</i>, <i>Salmonella enterica</i> Serotype Typhimurium, and <i>Pseudomonas aeruginosa</i> by Shengmei Pang, Mei Liu, Longlong Wang, Mingqing Shao, Guoqiang Zhu, Qiangde Duan

“…The results provide insights into the structure–function relationships of these flagellins and support their application in enhancing immune responses against diverse pathogens.…”
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A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…Treatment options are stratified by DDD severity to include conservative management (grades 1 and 2), minimally-invasive intradiscal therapies (grades 3 to 7), and more invasive surgical procedures (grade 8). …”
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Histological Alterations and Interferon-Gamma and AKT-mTOR Expression in an Experimental Model of Achilles Tendinopathy—A Comparison of Stem Cell and Amniotic Membrane Treatment by Guilherme Vieira Cavalcante, Rosangela Fedato, Lucia de Noronha, Seigo Nagashima, Ana Paula Camargo Martins, Márcia Olandoski, Ricardo Pinho, Aline Takejima, Rossana Simeoni, Julio Cesar Francisco, Luiz César Guarita-Souza

“…However, as tendon repair mechanisms are very complex, further studies should be carried out to verify the benefits of the tendon structure and function.…”
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Comprehensive analysis of CYP78A family genes reveals the involvement of CYP78A5 and CYP78A10 in fruit development in eggplant by Mengya Zhou, Liying Zhang, Shuangxia Luo, Lijun Song, Shuxing Shen, Jianjun Zhao, Qiang Li, Xueping Chen

“…This study provides a comprehensive overview of the SmCYP78As family, which would lay a foundation for further understanding of evolution and function of the SmCYP78A family.…”
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Genome-Wide Analysis of the <i>CDPK</i> Gene Family in <i>Populus tomentosa</i> and Their Expressions in Response to Arsenic Stress and Arbuscular Mycorrhizal Fungi Colonization by Minggui Gong, Jiajie Su, Shuaihui Wang, Youjia Wang, Weipeng Wang, Xuedong Chen, Qiaoming Zhang

“…However, there is still limited knowledge regarding the genes of the <i>Populus tomentosa CDPK</i> family and their underlying functions in response to arsenic (As) stress and arbuscular mycorrhizal fungi (AMF) colonization. …”
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Complete Blood Count and Monocyte Distribution Width–Based Machine Learning Algorithms for Sepsis Detection: Multicentric Development and External Validation Study by Andrea Campagner, Luisa Agnello, Anna Carobene, Andrea Padoan, Fabio Del Ben, Massimo Locatelli, Mario Plebani, Agostino Ognibene, Maria Lorubbio, Elena De Vecchi, Andrea Cortegiani, Elisa Piva, Donatella Poz, Francesco Curcio, Federico Cabitza, Marcello Ciaccio

“…The cohorts were selected to exhibit a variety of data distribution shifts compared to the training set, including label, covariate, and missing data shifts, enabling a conservative validation of the developed models. To improve generalizability and robustness to different types of distribution shifts, the developed ML models combine traditional methodologies with advanced techniques inspired by controllable artificial intelligence (AI), namely cautious classification, which gives the ML models the ability to abstain from making predictions, and explainable AI, which provides health operators with useful information about the models’ functioning. …”
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