Brachyury co-operates with polycomb protein RYBP to regulate gastrulation and axial elongation in vitro by Lilla Kokity, Lilla Kokity, Zsolt Czimmerer, Bernadett Benyhe-Kis, Bernadett Benyhe-Kis, Anna Poscher, Anna Poscher, Emese Belai, Emese Belai, Gábor Steinbach, Zoltan Lipinszki, Zoltan Lipinszki, Melinda Katalin Pirity

“…Finally, we identified BRACHYURY as a novel binding partner of RYBP and presented evidence of possible cooperative function during mesoderm formation and axial elongation. …”
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On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa by Corinna Benz, Maximilian W. D. Raas, Pragya Tripathi, Drahomíra Faktorová, Eelco C. Tromer, Bungo Akiyoshi, Julius Lukeš

“…Interestingly, we still could not detect orthologs for most of the kinetoplastid or canonical kinetochore subunits with few exceptions including a putative centromere-specific histone H3 variant (cenH3/CENP-A), the spindle checkpoint protein Mad2, the chromosomal passenger complex members Aurora and INCENP, and broadly conserved proteins like CLK kinase and the meiotic synaptonemal complex proteins SYCP2/3 that also function at kinetoplastid kinetochores. …”
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Identification of the Cytotoxic Transglutaminase from <i>Mycobacterium</i> spp. That Is Involved in RIPK1 Activation by Xinting Zhang, Yikai Zhang, Xiao Feng, Yueying Wang, Si-Shang Li, Mei-Yi Yan, Yi-Cheng Sun, Qi Jin, Feng Jiang

“…Research on <i>M. microti</i> is significant as it is a zoonotic pathogen that can spread between animals and humans. By exploring the function of a transglutaminase in <i>M. microti</i> (MmTG), which is widely distributed in <i>Mycobacterium</i> and other species, a potential cytotoxic effector has been characterized. …”
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Comparative Mitogenomics Provides Valuable Insights for the Phylogeny and New DNA Barcodes of <i>Ganoderma</i> by Ti-Qiang Chen, Chi Yang, Xiao-Lan Xu, Lin Yang, Huan-Qing He, Meng-Ting Weng, Zheng-He Ying, Xiao-Kun Shi, Meng-Guang Ding

“…<i>leucocontextum</i> H4, <i>G. lucidum</i> G6, <i>G. sinense</i> MZ96 and <i>G. tsugae</i> SS) were de novo assembled and given detail functional annotations. Collinearity analysis revealed that the four mitogenomes shared 82.93–92.02% similarity with their corresponding reference mitogenomes at the nucleotide level. …”
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Genome-Wide Identification and Expression Analysis of the <i>PsTPS</i> Gene Family in <i>Pisum sativum</i> by Hao Yuan, Baoxia Liu, Guwen Zhang, Zhijuan Feng, Bin Wang, Yuanpeng Bu, Yu Xu, Zhihong Sun, Na Liu, Yaming Gong

“…Phylogenetic analysis delineated evolutionary relationships, while gene structure analysis revealed compositional insights, and motif analysis provided functional insights. Cis-regulatory element identification predicted gene regulation patterns. …”
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Genome-Wide Identification and Evolutionary Analysis of <i>Ionotropic Receptors</i> Gene Family: Insights into Olfaction Ability Evolution and Antennal Expression Patterns in <i>Or... by Wen-Qi Yang, Ge Ding, Lin-Lin Wang, Chi-Jie Yin, Hai-Yue Wu, Hua-Bin Zhang, Qiu-Ning Liu, Sen-Hao Jiang, Bo-Ping Tang, Gang Wang, Dai-Zhen Zhang

“…These findings lay a foundation for further investigations and elucidate the functional roles of olfactory receptor genes in crustaceans.…”
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The transcriptional repressor Ctbp2 as a metabolite sensor regulating cardiomyocytes proliferation and heart regeneration by Yanting Meng, Jianwen Ding, Yanping Wang, Jing Wang, Wei Huang, Wenkang Jiang, Jiayi Li, Xiujuan Lang, Sifan Zhang, Yumei Liu, Xijun Liu, Hulun Li, Bo Sun

“…Abstract Background C-terminal binding protein-2 (Ctbp2) is an evolutionarily conserved transcriptional repressor that regulates fundamental processes such as cell proliferation and apoptosis. …”
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miR-34-5p mediates 20E-induced autophagy in the fat body of Bombyx mori by targeting Atg1 by Huili Qiao, Ziqian Tong, Yuanzhuo Wang, Juanjuan Yang, Yanyan Sun, Huixuan Shi, Zhuo Liu, Jianping Duan, Dandan Li, Yunchao Kan

“…Results We constructed six small RNA libraries using Bombyx mori fat body treated with 20E. Expression and functional analyses were conducted to identify 20E-responsive miRNAs. …”
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The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor by Nikola Sozańska, Barbara P. Klepka, Anna Niedzwiecka, Lilia Zhukova, Michał Dadlez, Beata Greb-Markiewicz, Andrzej Ożyhar, Aneta Tarczewska

“…Although TCF4 is essential for the proper development and function of the human body, there is a lack of fundamental knowledge about the structure of TCF4 since structural studies were previously limited exclusively to its bHLH. …”
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Several groups of LysM-RLKs are involved in symbiotic signal perception and arbuscular mycorrhiza establishment by Yi Ding, Zélie Lesterps, Virginie Gasciolli, Anne-Laure Fuchs, Mégane Gaston, Lauréna Medioni, Annélie de-Regibus, Céline Remblière, Céline Vicédo, Sandra Bensmihen, Jean Jacques Bono, Julie Cullimore, Guilhem Reyt, Marion Dalmais, Christine Saffray, Solène Mazeau, Abdelhafid Bendahmane, Richard Sibout, Michiel Vandenbussche, Jacques Rouster, Tongming Wang, Guanghua He, Arnaud Masselin, Sylvain Cottaz, Sébastien Fort, Benoit Lefebvre

“…While LYR-IB knock out mutants had a reduced AMF colonization in several species, constitutive/ectopic expression in wheat increased AMF colonization. LYR-IB function is conserved in all tested angiosperms, but in most japonica rice a deletion creates a frameshift in the gene, explaining differences in AM phenotypes between rice and other monocot single LYR-IA mutants. …”
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Analyzing the Reproductive Characteristics of the Naked Carp Gymnocypris Przewalskii (Kessler) Based on the Oxygen Isotopes of Otolith Core Using SHRIMP by Ling ZHOU, Linbo QIAN, Sumei ZHAO, Xiulan ZHANG, Yinglie LIU, Qiaoling TANG, Jie YUAN

“…Otolith, a calcium carbonate mineral in bony fish, has both auditory and balancing functions and is known as the “recorder” of time and water environment. …”
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In vitro and ex vivo screening of microRNA combinations with enhanced cell penetrating peptides to stimulate intervertebral disc regeneration by Tara Ní Néill, Marcos N. Barcellona, Niamh Wilson, Fergal J. O'Brien, James E. Dixon, Caroline M. Curtin, Conor T. Buckley

“…Abstract Background Low back pain (LBP) is predominantly caused by degeneration of the intervertebral disc (IVD) and central nucleus pulposus (NP) region. Conservative treatments fail to restore disc function, motivating the exploration of nucleic acid therapies, such as the use of microRNAs (miRNAs). miRNAs have the potential to modulate expression of discogenic factors, while silencing the catabolic cascade associated with degeneration. …”
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Correlation of precancerous lesion incidence with duodenogastric reflux and N-nitroso compound duration at reflux and antireflux stomach surgery: An experimental study by Zlatić Aleksandar, Marinković Mirjana, Mihailović Dragan, Radojković Milan, Radovanović-Dinić Biljana, Đorđević Miodrag, Korica Milan, Veljković Radovan

“…Duodenogastric reflux occurs after gastroenteroanastomosis, with or without resection of the stomach (Billroth I, Billroth II), after vagotomy and pyloroplasty, gastroduodenostomy as well as in conservatively treated patients. The aim of this study was to analyse the effect of carcinogenic N-nitroso compounds (MNNG) influence in conjunction with duodenogastric reflux, in the function of time for precancerous lesions development in gastric mucosa. …”
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Experimental Study on Hydraulic Characteristics of Fish-friendly Culverts with Baffles by MAO Jing-qiao, LU Peng, GONG Yi-qing, GAO Huan, DAI Jie

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The AusAB non-ribosomal peptide synthetase of Staphylococcus aureus preferentially generates phevalin in host-mimicking media by Adriana Moldovan, Markus Krischke, Claudia Huber, Clara Hans, Martin J. Müller, Wolfgang Eisenreich, Thomas Rudel, Martin J. Fraunholz

“…In addition, owing to its minimal canonical NRPS structure and autonomous function (i.e., most NRPS pathways require the assembly of several NRPS proteins), AusA represents an excellent model system for studying such molecular assembly lines. …”
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Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation by Hongyan Xu, Hongyan Xu, Guocai Han, Yanyan Li, Qing Meng, Qing Meng, Yang Zhang, Yayi Wang, Songling Li

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Genome-Wide Identification and Pollen-Specific Promoter Analysis of the <i>DIR</i> Gene Family in <i>Rosa chinensis</i> by Qijing Dong, Qian Yang, Zitong Wang, Yuan Zhao, Sixu Guo, Yifang Peng, Qi Li, Yu Han

“…Dirigent proteins (DIRs) are pivotal regulators of lignin/lignan biosynthesis and play multifaceted roles in plant development and stress adaptation. Despite their functional significance, <i>DIR</i> genes remain unexplored in <i>Rosa chinensis</i>, a globally important woody ornamental species. …”
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Large-scale genomic analysis reveals significant role of insertion sequences in antimicrobial resistance of Acinetobacter baumannii by Fei Xie, Lifeng Wang, Song Li, Long Hu, Yanhua Wen, Xuming Li, Kun Ye, Zhimei Duan, Qi Wang, Yuanlin Guan, Ye Zhang, Qiqi Shi, Jiyong Yang, Han Xia, Lixin Xie

“…This significantly enhances the accuracy of AMR prediction, emphasizing the pivotal function of IS elements in antibiotic resistance. Notably, we uncover a series of conserved sequence patterns linking IS elements and ARGs, which outperform ARGs alone in phenotypic prediction. …”
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Organic substitution regulated the soil microbial communities by modifying nutrient limitations in saline-alkaline soils by Yue Han, Zhanli Ma, Rui Chen, Yue Wen, Yonghui Liang, Jinzhu Zhang, Wenhao Li, Zhenhua Wang

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Crosstalk of autophagy and ferroptosis in cardiovascular diseases: from pathophysiology to novel therapy by Changhao Hu, Siying Gao, Xinyi Li, Kaiqing Yang, Ye Cheng, Wei Guo, Huijun Wu, Xueqin Cheng, Weiwen Zhao, Yuxuan Kong, Haoyuan Hu, Songyun Wang

“…Key regulatory molecules, such as Beclin-1 and nuclear factor E2-related factor 2 (Nrf2), function as central hubs, orchestrating the intricate interplay between autophagy and ferroptosis. …”
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