Mitochondrial targeting of Candida albicans SPFH proteins and requirement of stomatins for SDS-induced stress tolerance by Hyunjeong Kim, Marienela Y. Heredia, Xiao Chen, Maisha Ahmed, Mohammad Qasim, Tracy L. Callender, Aaron D. Hernday, Jason M. Rauceo

“…Here, we sought to determine the cellular localization and functionally characterize stomatin-like protein 2 (Slp2), prohibitin-1 (Phb1), prohibitin-2 (Phb2), and prohibitin-12 (Phb12) in C. albicans. …”
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Experimental Evaluation of Relationship Between Radiofrequency Heating Near Implanted Conductive Devices, Scanner-Reported B_1+rms, and Transmit Power by David H. Gultekin, John T. Vaughan, Devashish Shrivastava

“…Additional studies across other MR scanners are needed to better understand the extent of variation in RF-induced heating near implanted conductive devices as a function of scanner-reported B_1+rms and RF power to develop conservative and reliable patient labeling.…”
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Monoclonal antibody and B-cell epitope mapping of the VP7 protein in bluetongue virus by Xin-Bing Hu, Jing Xu, Yu Zhang, Fan-Hua Meng, Zhan-Cheng Tian, Gui-Quan Guan, Jian-Xun Luo, Hong Yin, Jun-Zheng Du

“…These specific mAbs and identified B-cell epitopes provided key insights into the structure and function of VP7, while facilitating the development of BTV diagnostics and the design of epitope-based vaccines.…”
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Pore-Forming Protein LIN-24 Enhances Starvation Resilience in <i>Caenorhabditis elegans</i> by Modulating Lipid Metabolism and Mitochondrial Dynamics by Xinqiang Lan, Mengqi Yang, Jiali Wang, Chunping Huang, Andong Wu, Leilei Cui, Yingqi Guo, Lin Zeng, Xiaolong Guo, Yun Zhang, Yang Xiang, Qiquan Wang

“…However, the role of PFPs in non-immune functions, particularly in metabolic and structural adaptations to starvation, is less explored. …”
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Dose–response effectiveness of focused shockwave therapy on ultrasonographic muscular properties in patients with stroke exhibiting ankle spasticity by Shu-Mei Yang, Hung-Hsi Lin, Yen-Hua Chen, You-Lin Lu, Chueh-Hung Wu, Wen-Shiang Chen, Meng-Ting Lin

“…These findings suggest that increased ESWT dosage may enhance muscle architecture and function in stroke rehabilitation.…”
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O2-self-supplying and glutathione-depleting scaffold for synergistic cancer therapy by Jiajia Zeng, Chongxian He, Xinna Bai, Cijun Shuai, Hao Pan

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CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility by Bingbing Wu, Chenghong Long, Yuzhuo Yang, Zhe Zhang, Shuang Ma, Yanjie Ma, Huafang Wei, Jinghe Li, Hui Jiang, Wei Li, Chao Liu

“…Further analysis revealed that CCDC113 could bind to CFAP57 and CFAP91, and function as an adaptor protein for the connection of radial spokes, nexin-dynein regulatory complex (N-DRC), and doublet microtubules (DMTs) in the sperm axoneme. …”
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Fisiologi dan Gangguan Keseimbangan Natrium, Kalium dan Klorida serta Pemeriksaan Laboratorium by Rismawati Yaswir, Ira Ferawati

“…Electrolyte concentration<br />which abnormal can cause many troubles. Conservancy of osmotic pressure and distribution some human being<br />body fluid compartment are especial function four major electrolyte, that is natrium (Na+), potassium (K+), chloride<br />(Cl-), and bicarbonate (HCO3-). …”
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Lipoprotein N-terminal modification in Bacillus: a new paradigm for extracellular acetylation and species-dependent Toll-like receptor 2 immunomodulation by Gloria Komazin, Rachel M. Wigmore, Aditi M. Ranade, Amena A. Rizk, John H. Gardiner, Timothy C. Meredith

“…While Ac-LP biosynthetic pathway genes appear to be universally conserved in all Bacillus spp., those associated with pathogenic lineages have often lost function. …”
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Mitochondrial neurogastrointestinal encephalomyopathy in china: a novel TYMP variant and comprehensive clinical-genetic insights by Xuebi Xu, Junhui Xia, Fei Xu, Mingshan Wang, Lihong Yang, Xiaoli Chen

“…In silico analysis confirmed that both variants are highly conserved and likely pathogenic. Protein modeling revealed that both variants compromise structural integrity and conformation, impairing TP function. …”
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Pharmacologic treatment of attention deficit hyperactivity disorder in adults: A systematic review and network meta-analysis. by Jesse Elliott, Amy Johnston, Don Husereau, Shannon E Kelly, Caroline Eagles, Alice Charach, Shu-Ching Hsieh, Zemin Bai, Alomgir Hossain, Becky Skidmore, Eva Tsakonas, Dagmara Chojecki, Muhammad Mamdani, George A Wells

“…The primary outcome was clinical response; secondary outcomes were quality of life, executive function, driving behaviour, withdrawals due to adverse events, treatment discontinuation, serious adverse events, hospitalization, cardiovascular adverse events, and emergency department visits. …”
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Sucrose synthase gene family in common bean during pod filling subjected to moisture restriction by Norma Cecilia Morales-Elias, Eleazar Martínez-Barajas, Lilia Angélica Bernal-Gracida, Monserrat Vázquez-Sánchez, Iris Grisel Galván-Escobedo, Jose Salud Rodriguez-Zavala, Amelia López-Herrera, Cecilia Beatriz Peña-Valdivia, Antonio García-Esteva, Carlos Alberto Cruz-Cruz, María Teresa González-Arnao, José Cruz Jiménez-Galindo, Daniel Padilla-Chacón

“…The results provide a systematic overview of the PvSUS gene family in P. vulgaris, offering a framework for further research and the potential functional application of PvSUS genes.…”
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BdNRT2A and BdNRT3.2 Are the Major Components of the High‐Affinity Nitrate Transport System in Brachypodium distachyon by Laure C. David, Mathilde Grégoire, Patrick Berquin, Anne Marmagne, Marion Dalmais, Abdelhafid Bendahmane, Tony J. Miller, Anne Krapp, Françoise Daniel‐Vedele, Thomas Girin, Sylvie Ferrario‐Méry

“…An effective nitrate transport in the heterologous expression system Xenopus oocytes required the coexpression of BdNRT2A and BdNRT3.2 that characterizes two‐component system of the HATS. Functional interaction between BdNRT2A‐GFP and BdNRT3.2‐RFP fusion proteins was observed at the plasma membrane in Arabidopsis protoplasts in transient expression experiments with BdNRT3.2 being necessary for the plasma membrane localization of BdNRT2A. …”
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Integrin beta‐like 1 is regulated by DNA methylation and increased in heart failure patients by Lauren Kerrigan, Kevin Edgar, Adam Russell‐Hallinan, Oisin Cappa, Nadezhda Glezeva, Carlos Galan‐Arriola, Eduardo Oliver, Borja Ibanez, John Baugh, Patrick Collier, Mark Ledwidge, Ken McDonald, David Simpson, Sudipto Das, David J. Grieve, Chris J. Watson

“…Single nuclei RNA sequencing highlighted that Itgbl1 is primarily expressed in cardiac fibroblasts, while functional studies elucidated a role for ITGBL1 in cardiac fibroblast migration, evident in 50% reduced 24 h fibroblast wound closure occurring subsequent to siRNA‐targeted ITGBL1 knockdown. …”
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Deciphering the tumor ecosystem dynamics undergoing immunochemotherapy therapy across multiple cancer types unveils the immunosuppressive role of S100A4 in fibroblasts by promoting... by Bo Yang, Bo Yang, Ruiji Chen, Ruiji Chen, Mali Zu, Jie Yao, Hong Ren, Hong Ren, Yingxue Lin, Yingxue Lin, Bo Zhang, Tianjiao Ji, Yang Liu

“…Cell-cell communication analysis, Meta-Programs (MPs) via non-negative matrix factorization, and functional enrichment were performed. Immunohistochemistry (IHC) and Western blot validated S100A4 expression and PD-L1 induction in vitro.ResultsWe constructed a single-cell map across cancer types and systematically characterized dynamic changes in tumor cells and diverse microenvironmental cell populations following neoadjuvant therapy, along with thier gene expression and pathway alterations. …”
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Sedimentary records from human-made talavs reveal climate risks in semi-arid watersheds of India by Atreyee Bhattacharya, S. Sarkar, J.S. Leonard-Pingel, A.V. Michelson, A Anoop, P.K. Mishra, S. Chakraborty, K Bajaj, U Singh, V Petryshyn, R. Ray, P.D. Sabale, A Bhattacharya, M. Kirby, A. Bazaz

“…We also find that while run-off is sensitive to divisional expressions of hydroclimate variability (associated with the ISM), the intensity of run-off and resultant erosion is not a simple function of rainfall intensity; in fact, we find that land-surface erodibility is impacted by land-use patterns and incidence of prior climate events (e.g. flooding) and that these compunded effects are more prominent in drier catchments (which also experience more extreme climate events) than in the wetter parts of the watersheds. …”
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Interspecies signaling modulates the biosynthesis of antimicrobial secondary metabolites related to biological control activities of Pseudomonas fluorescens 2P24 by Nannan Zhang, Xianfeng Zhu, Xuanying Tao, Jie Li, Qi Tang, Xiaochun Liu, Li-Ming Luo, Pingping Zhang, Li-Qun Zhang, Yong-Xing He, Honghua Ge

“…Plant growth-promoting bacterium Pseudomonas produces a spectrum of important antibiotics to inhibit plant pathogens, albeit with an associated metabolic burden. Antibiotics could function as intra- and interspecies signals at subinhibitory concentrations to coordinate gene expression and microbial behaviors. …”
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A novel Alteromonas phage with tail fiber containing six potential iron-binding domains by Chen Yu, Meishun Yu, Ruijie Ma, Shuzhen Wei, Min Jin, Nianzhi Jiao, Qiang Zheng, Rui Zhang, Xuejin Feng

“…Remarkably, the prediction of the R22Y tail fiber structure revealed six conserved histidine residues (HxH motifs) that could potentially bind iron ions, suggesting that alterophages may function as organic iron-binding ligands in the marine environment. …”
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HilD-regulated chemotaxis proteins contribute to Salmonella Typhimurium colonization in the gut by Kendal G. Cooper, Laszlo Kari, Audrey Chong, Naman Tandon, Kathleen Doran, Lidiane Gomes Da Silva, Diane C. Cockrell, Arden Baylink, Olivia Steele-Mortimer

“…We found that the conserved cysteine is required for McpA function in the mouse gut, thus demonstrating a virulence role for the CZB Zn2+-binding site during infection.IMPORTANCEThe gut-adapted bacterium Salmonella Typhimurium causes inflammatory diarrhea via a process that involves active invasion of intestinal epithelial cells, secretion of inflammatory molecules, and recruitment of immune cells. …”
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Metabolic consequences of altered kidney glucose reabsorption under normoglycemic conditions by Majdoleen Ahmad, Anna Permyakova, Saja Baraghithy, Nilanjan Sahu, Ifat Abramovich, Bella Agranovich, Ori Shalev, Aviram Kogot-Levin, Alina Nemirovski, Eyal Gottlieb, Rinat Abramovitch, Gil Leibowitz, Liad Hinden, Joseph Tam

“…While GLUT2's role has been studied in diabetic conditions, its function in kidney proximal tubule cells (KPTCs) under normo-physiological conditions remains unclear. …”
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