Feasibility of occlusal plane in predicting the changes in anteroposterior mandibular position: a comprehensive analysis using deep learning-based three-dimensional models by Bingran Du, Kaichen Li, Zhiling Shen, Yihang Cheng, Jiayan Yu, Yaopeng Pan, Ziyan Huang, Fei Hu, Xiaohui Rausch-Fan, Yuanpeng Zhu, Xueyang Zhang

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X-Ray Crystal and Cryo-Electron Microscopy Structure Analysis Unravels How the Unique Thylakoid Lipid Composition Is Utilized by Cytochrome <i>b</i>₆<i>f</i> for Driving... by Radka Vladkova

“…These findings firmly validate the HMM model and underscore the STs as the first recognized functional process that fully utilizes the unique and evolutionarily conserved composition of just four thylakoid lipid classes. …”
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The clinical efficacy of hybrid surgery based on the Waveflex semi-rigid dynamic internal fixation system for the treatment of lumbar degenerative diseases: over three-year follow-... by Zhiwu Zhang, Jiashen Shao, Nan Su, Xiang Li, Qi Fei, Yong Yang, Hai Meng

“…Clinical efficacy was evaluated based on pain intensity (measured by the Visual Analogue Scale, VAS), functional disability (assessed via the Oswestry Disability Index, ODI), incidence of postoperative complications, and patient satisfaction level. …”
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Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains by Yue Xiang, Saixian Zhang, Yi Huang, Zhuqing Zheng, Jiahui Sun, Qiulin Zhao, Peng Zhou, Xiaolong Qi, Jingjin Li, Fuyang Xiong, Jing Xu, Shengquan Wang, Liangliang Fu, Xinyun Li

“…Finally, cross-species analysis suggested that, compared to humans, the proportion of sequence-conserved and functionally conserved regulatory elements in each cell type appears to be higher in pigs than in mice. …”
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Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease by Haixia Su, Guoqing Wu, Muya Xiong, Yuhang Wang, Junyuan Cao, Mengyuan You, Yingchun Xiang, Tianqing Nie, Minjun Li, Gengfu Xiao, Leike Zhang, Qiang Shao, Yechun Xu

“…Therefore, this work provides a comprehensive understanding of the MPXV I7L protease's structure, dynamics, and function, and presents an example of successful rational design of covalent peptidomimetic inhibitors, serving as a good starting point for drug development against MPXV.…”
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Macrophage-Specific Progranulin Deficiency Prevents Diet-Induced Obesity through the Inhibition of Hypothalamic and Adipose Tissue Inflammation by Chan Hee Lee, Chae Beom Park, Hyun-Kyong Kim, Won Hee Jang, Se Hee Min, Jae Bum Kim, Min-Seon Kim

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Treatment of Hallux Rigidus: Comparison of Hemiarthroplasty with Cartiva Implant, Allograft Interpositional Arthroplasty, and Arthrodesis by Ryan Sanii MD, MPH, Kevin Phan MD, Drew Krumm MD, Daniel J. Patton MD, Tyler Madden MD, John G. Anderson MD, John D. Maskill MD, Donald R. Bohay MD, FACS, Michelle A. Padley PhD, Cameron G. Patthanacharoenphon MD

“…Conclusion: Pain and function may be slightly more improved with interpositional arthroplasty and arthrodesis for the treatment of HR, when compared to hemiarthroplasty with the Cartiva implant. …”
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Diagnostics and treatment of cardiac achalasia and cardiospasm: guidelines of the Russian gastroenterological association by V. T. Ivashkin, A. S. Trukhmanov, E. A. Godzhello, I. V. Mayev, Yu. V. Evsyutina, T. L. Lapina, O. A. Storonova

“…Cardiac achalasia is primary esophageal motor function disorder manifested by impaired lower esophageal sphincter relaxation and defects of thoracic esophagus peristalsis. …”
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Intratentacular budding and zooid-dynamics in two coral genera by Matan Yuval, Amit Peleg, Elvan Ceyhan, Dan Tchernov, Yossi Loya, Avi Bar-Massada, Tali Treibitz

“…The patterns of addition of zooids (budding mechanics) determine much of the colony’s shape and function. Yet because zooids are small in size and large in numbers, ecological studies often focus on coral colonies as unitary organisms and little is known about how zooids vary within and between colonies and species. …”
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Cloning and Analysis of the Expansin Gene BdEXP1 from Migration Plant parasitic Nematode (Bursaphelenchus doui) by Kaiyang GUO, Shifeng LIN, Rengang WANG, Li LI, Jie ZHANG, Shizhou YU, Zili WANG, Guoqin LIU

“…【Objective】An expansin gene BdEXP1 was cloned from Bursaphelenchus doui, and its expression characteristics were investigated in order to provide reference for the in-depth study of the function of BdEXP1 gene in the interactions between B. doui and hosts.…”
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CRISPR/Cas9-mediated simultaneous targeting of GmP34 and its homologs produces T-DNA-free soybean mutants with reduced allergenic potential by Dongwon Baek, Byung Jun Jin, Mi Suk Park, Ye Jin Cha, Tae Hee Han, Ye Na Jang, Su Bin Kim, Sang In Shim, Jong-Il Chung, Hyun Jin Chun, Min Chul Kim, Min Chul Kim, Min Chul Kim

“…Phylogenetic analysis and domain characterization identified GmP34h1 and GmP34h2 as the closest homologs to GmP34, with conserved allergenic peptide motifs. Gene expression profiling revealed similar expression patterns of all three genes during seed maturation, indicating potential functional redundancy. …”
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Involvement of an orphan response regulator of the two-component regulatory system in the formation of physiologically mature sporangia in Actinoplanes missouriensis by Takuya Akutsu, Zhuwen Tan, Aiko Hirata, Takeaki Tezuka, Yasuo Ohnishi

“…Based on the amino acid sequence and predicted structure, the function of AsfR appeared to be controlled by the phosphorylation of Asp-72. …”
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Chlamydomonas IC97, an intermediate chain of the flagellar dynein f/I1, is required for normal flagellar and cellular motility by Ryosuke Yamamoto, Yui Tanaka, Shunsuke Orii, Kogiku Shiba, Kazuo Inaba, Takahide Kon

“…IC97 is an evolutionarily conserved intermediate chain of IDA f/I1, but the detailed molecular functions of IC97 in flagellar motility have not been elucidated. …”
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Impact of continuous cropping on microbial biomass and enzyme activities in the surface layer of gravel-sand mulched soils in arid Northwest China: A Meta-analysis by XUE Yinmin, JIA Zhenjiang, MA Dongxiang, WU Yangyang, HUANG Yahao, HE Xuezhong, WU Xiu, LI Wangcheng

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Genome-Wide Identification, Characterization, and Expression Analysis of <i>VQ</i> Gene Family in <i>Salix suchowensis</i> Under Abiotic Stresses and Hormone Treatments by Hongjuan Wang, Yujiao Wang, Yongle Wang, Jiabao Zhu, Lei Chen, Xiaoming Yan, Chun Yu, Benli Jiang

“…Certain <i>SsVQ</i> genes showed co-expression under abiotic/hormonal stresses, implying synergistic functions. Paralogous gene pairs exhibited stronger co-expression than non-paralogous pairs. …”
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Lower expression of miR-218 in human breast cancer is associated with lymph node metastases, higher grades, and poorer prognosis by Fereshteh Ahmadinejad, Seyed Javad Mowla, Mohammad-Amin Honardoost, Mostafa Gholami Arjenaki, Mohammad Moazeni-Bistgani, Soleyman Kheiri, Hossein Teimori

“…Finally, to better understand biological function of miR-218 in breast cancer, we performed in silico Gene Ontology and signaling pathway enrichment analysis on miR-218 targetome. …”
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ZmNF-YB10, a maize NF-Y transcription factor, positively regulates drought and salt stress response in Arabidopsis thaliana by Yimeng Wang, Peng Jiao, Chenyang Wu, Chunlai Wang, Ke Shi, Xiaoqi Gao, Shuyan Guan, Yiyong Ma

“…In yeast cells, ZmNF-YB10 exhibited a biological function that enhances salt and drought tolerance. …”
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Association of patent ductus arteriosus treatment in extremely low gestational age neonates with two year kidney outcomes: a secondary analysis of the preterm erythropoietin neurop... by Paige E. Condit, Ronnie Guillet, Dinushan Kaluarachchi, Russell L. Griffin, Shina Menon, David J. Askenazi, Matthew W. Harer

“…Little is known about how different management approaches to a PDA, either conservative management or active management and either medical or surgical treatment, in preterm neonates impact kidney function over the longer term. …”
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ABA-activated subclass III SnRK2s control kernel maturation in maize by Yayun Wang, Tiandan Long, Aying Qin, Qiang Liao, Hao Wang, Junjie Zhang, Hanmei Liu, Yinghong Liu, Yufeng Hu, Yubi Huang, Yangping Li

“…Knockout of ZmSnRK2s demonstrated that subclass III ZmSnRK2s are required for kernel maturation in maize, and the loss-of-function of subclass III ZmSnRK2s showed a disruption in kernel dehydration and dormancy. …”
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Disordered regions and folded modules in CAF-1 promote histone deposition in Schizosaccharomyces pombe by Fouad Ouasti, Maxime Audin, Karine Fréon, Jean-Pierre Quivy, Mehdi Tachekort, Elizabeth Cesard, Aurélien Thureau, Virginie Ropars, Paloma Fernández Varela, Gwenaelle Moal, Ibrahim Soumana Adamou, Aleksandra Uryga, Pierre Legrand, Jessica Andreani, Raphaël Guerois, Geneviève Almouzni, Sarah Lambert, Francoise Ochsenbein

“…This process relies on the evolutionary conserved histone chaperone CAF-1 for which the links between structure and functions are still a puzzle. …”
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