Comparative Genomics of Rhamnolipid Synthesis and Monoaromatic Hydrocarbon Tolerance Genes in Environmental Pseudomonas aeruginosa strains [version 2; peer review: 2 approved] by Sandro B. Martel-Torres, Camila Castillo-Vilcahuaman, ROGER A. PALOMINO HUARCAYA, Susana M. Gutiérrez Moreno, Fernando A. Merino Rafael

“…DNA extraction, sequencing, and quality-controlled assembly, functional genome annotation was performed using BAKTA. …”
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Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus by Lea Zillich, Annasara Artioli, Veronika Pohořalá, Eric Zillich, Laura Stertz, Hanna Belschner, Ammar Jabali, Josef Frank, Fabian Streit, Diana Avetyan, Maja P. Völker, Svenja Müller, Anita C. Hansson, Thomas D. Meyer, Marcella Rietschel, Julia Ladewig, Rainer Spanagel, Ana M. M. Oliveira, Consuelo Walss-Bass, Rick E. Bernardi, Philipp Koch, Stephanie H. Witt

“…Abstract Structural and functional alterations in the brain’s reward circuitry are present in cocaine use disorder (CocUD), but their molecular underpinnings remain unclear. …”
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Approximating the Proportion of Individuals With Kidney Failure Who Die Without Kidney Replacement Therapy in Ontario, Canada by Andrea C. Cowan, Nivethika Jeyakumar, Amit X Garg, Stephanie Dixon, Bin Luo, Peter G Blake

“…In this last cohort, patients whose kidney function improved (evidence of an eGFR > 10 mL/min/1.73 m 2 ) or who received a transplant during follow-up were excluded from the analysis. …”
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Transcriptional regulatory network reveals key transcription factors for regulating agronomic traits in soybean by Wu Jiao, Mangmang Wang, Yijian Guan, Wei Guo, Chang Zhang, Yuanchun Wei, Zhenwei Zhao, Hongyu Ma, Longfei Wang, Xinyu Jiang, Wenxue Ye, Dong Cao, Qingxin Song

“…To accelerate utilization of SoyGRN, we develop an interactive webserver ( www.soytfbase.cn ) for soybean community to explore functional TFs involved in trait regulation. Conclusions Overall, our study unravels intricate landscape of TF-target interactions in soybean and provides a valuable resource for dissecting key regulators for control of agronomic traits to accelerate soybean improvement.…”
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Exceptional Heme Tolerance in <i>Serratia plymuthica</i>: Proteomic Insights into Oxidative Stress Adaptation in the <i>Aedes aegypti</i> Midgut by Sâmella da Hora Machado, Rívea Cristina Custódio Rodrigues, Maria Aparecida Aride Bertonceli, Analiz de Oliveira Gaio, Gabriela Petroceli-Mota, Ricardo de Souza Reis, Marília Amorim Berbert-Molina, Vanildo Silveira, Francisco José Alves Lemos

“…Upregulated proteins were associated with antioxidant defense, heme transport, and redox regulation, whereas downregulated proteins suggested metabolic reprogramming to conserve energy under stress. Functional enrichment analysis revealed significant alterations in transmembrane transport, oxidative stress response, and central metabolism. …”
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Loss of CTRP10 results in female obesity with preserved metabolic health by Fangluo Chen, Dylan C Sarver, Muzna Saqib, Leandro M Velez, Susan Aja, Marcus M Seldin, G William Wong

“…Transcriptional correlation of the differentially expressed gene (DEG) orthologs in humans also shows sex differences in gene connectivity within and across metabolic tissues, underscoring the conserved sex-dependent function of CTRP10. Collectively, our findings suggest that CTRP10 negatively regulates body weight in females, and that loss of CTRP10 results in benign obesity with largely preserved insulin sensitivity and metabolic health. …”
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Surgical Management of Osteochondritis Dissecans of the Glenoid via Autologous Bone Marrow Aspirate Concentrate and Extracellular Matrix Graft in an Eighteen-Year-Old College Pitch... by Mitchell T. Tingey BS, Mark A. Glover BS, Jeffery D. St. Jeor MD, Nicholas A. Trasolini MD, Benjamin S. Albertson MD, Anthony P. Fiegen MD, Brian R. Waterman MD

“…It allows for arthroscopic treatment with long-term success in the treatment of pain and function. Patient Consent Disclosure Statement: The author(s) attests that consent has been obtained from any patient(s) appearing in this publication. …”
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Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species by Kazuya Maeda, Takuya Sumita, Oumi Nishi, Hirotoshi Sushida, Yumiko Higashi, Hiroyuki Nakagawa, Tomoko Suzuki, Eishin Iwao, Much Zaenal Fanani, Yoshiaki Nishiya, Yuichiro Iida

“…Functional disruption of DPH1 orthologous genes encoding sesquiterpene cyclase in H. pulvinata, A. oryzae, and its close relative A. flavus revealed that deoxyphomenone in H. pulvinata had exogenic antifungal activity against C. fulvum and controlled endogenic sporulation in Aspergillus species. …”
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A plasmid-mediated type III secretion system associated with invasiveness and diarrheagenicity of Providencia rustigianii by Jayedul Hassan, Atsushi Hinenoya, Noritoshi Hatanaka, Sharda Prasad Awasthi, Goutham Belagula Manjunath, Nahid Rahman, Jyoji Yamate, Shota Nakamura, Daisuke Motooka, Akira Nagita, Shah M. Faruque, Shinji Yamasaki

“…This is the first report of a functional and mobile T3SS in P. rustigianii and its association with invasiveness and diarrheagenicity of this bacterium. …”
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Genome-Wide Identification and Characterization of the mTERF Gene Family in Spinach and the Role of <i>SomTERF5</i> in Response to Heat Stress by Ziyue Sun, Li Li, Yaqi Liu, Yanshuang Liu, Gaojian Li, Yueyue Li, Qingbo Yu, Meihong Sun, Xiaofeng Xu

“…Subcellular localization predictions indicated that these proteins predominantly target chloroplasts and mitochondria. Conserved domain analyses confirmed that all SomTERF proteins possess canonical mTERF domains and ten conserved motifs. …”
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Transcriptomic analysis of melatonin-mediated drought stress response genes in alfalfa during germination period by Xiaoxia Zhang, Wenxuan Zhu, Zirui Liu, Xiangling Ren, Yingao Li, Guomin Li, Jingzhuo Wang, Xiaoyan Zhu, Yinghua Shi, Chengzhang Wang, Defeng Li, Hao Sun

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The role of healthy wetlands in mitigating volcanic tephra impacts in Northern Patagonia by Andrea Soledad Enriquez, Manuela Fernández, Fernando Umaña, María Victoria Cremona

“…The plant growing season following the eruption generated, on average, 3929±2146 kg DM ha−1, indicating an active functional wet meadow recovery despite a 25-20% reduction in ANPP due to the tephra effect. …”
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Patients from low-middlProfile and management of patients from low-middle socioeconomic status with thoracic traumae socioeconomic status with thoracic trauma: A prospective observ... by Heleen van Aswegen, Ronel Roos, Elizma Haarhoff, Josslyn de Kock, Humairaa Ebrahim, Sameer Tootla, Muhammad Vally, Monika Fagevik Olsén

“…Management involved functional activities (cycling [n = 71/149; 48%], early mobilisation [n = 120/174; 69%]), lung volume enhancement (deep breathing exercises [n = 97/174; 56%], positive expiratory pressure [n = 98/174; 56%]), secretion removal (active coughing [n = 60/174; 34%]). …”
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The Mechanism of Aniline Blue Degradation by Short-Chain Dehydrogenase (<i>SDRz</i>) in <i>Comamonas testosteroni</i> by Chuanzhi Zhang, Yong Huang, Jiaxin He, Lei He, Jinyuan Zhang, Lijing Yu, Elshan Musazade, Edmund Maser, Guangming Xiong, Miao Xu, Liquan Guo

“…Functional validation using an <i>SDRz</i>-knockout strain (CT-ΔSDRz) and an <i>SDRz</i>-expressioning strains (E-SDRz) confirmed that SDRz is essential for aniline blue degradation. …”
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The male and female genomes of golden pompano (Trachinotus ovatus) provide insights into the sex chromosome evolution and rapid growth by Honglin Luo, Yongde Zhang, Fuyan Liu, Yongzhen Zhao, Jinxia Peng, Yuhui Xu, Xiuli Chen, Yin Huang, Changmian Ji, Qingyun Liu, Pingping He, Pengfei Feng, Chunling Yang, Pinyuan Wei, Zhenhua Ma, Jianguang Qin, Shengjie Zhou, Shiming Dai, Yaoyao Zhang, Zhongquan Zhao, Hongling Liu, Hongkun Zheng, Jisen Zhang, Yong Lin, Xiaohan Chen

“…Zebrafish model was used to investigate the functions of growth candidate gene. Results: Female (644.45 Mb) and male (652.12 Mb) genomes of golden pompano were assembled and annotated at the chromosome level. …”
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Beyond the closed-forest paradigm: Cross-scale vegetation structure in temperate Europe before the late-Quaternary megafauna extinctions by Elena A. Pearce, Florence Mazier, Charles W. Davison, Oliver Baines, Szymon Czyżewski, Ralph Fyfe, Krzysztof Bińka, Steve Boreham, Jacques-Louis de Beaulieu, Cunhai Gao, Wojciech Granoszewski, Anna Hrynowiecka, Małgorzata Malkiewicz, Tim Mighall, Bożena Noryśkiewicz, Irena Agnieszka Pidek, Jaqueline Strahl, Hanna Winter, Jens-Christian Svenning

“…This scale-explicit evidence of Last Interglacial vegetation complexity offers insights into the biodiversity and ecological functionality of pre-anthropogenic ecosystems, with implications for modern conservation and rewilding, particularly in maintaining diversity through disturbance and megafaunal interactions.…”
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Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice by George Ssebyatika, Katja Dinkelborg, Luisa J. Ströh, Florian Hinte, Laura Corneillie, Lucas Hueffner, Elina M. Guzman, Prossie L. Nankya, Nina Plückebaum, Lukas Fehlau, Jonathan Garn, Nele Meyer, Sarah Prallet, Ann-Kathrin Mehnert, Anke R. M. Kraft, Lieven Verhoye, Carina Jacobsen, Eike Steinmann, Heiner Wedemeyer, Abel Viejo-Borbolla, Viet Loan Dao Thi, Thomas Pietschmann, Marc Lütgehetmann, Philip Meuleman, Maura Dandri, Thomas Krey, Patrick Behrendt

“…Here, we report combined functional, biochemical, and X-ray crystallographic studies that characterize the human antibody response in convalescent HEV patients. …”
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Genomic island-encoded LmiA regulates acid resistance and biofilm formation in enterohemorrhagic Escherichia coli O157:H7 by Hongmin Sun, Lingyan Jiang, Jingnan Chen, Chenbo Kang, Jun Yan, Shuai Ma, Mengjie Zhao, Houliang Guo, Bin Yang

“…Our findings provide essential insight into the regulatory function of LmiA in EHEC O157:H7, particularly its role in regulating acid resistance and biofilm formation.…”
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Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa) by Mengmeng Shi, Yike Wang, Peng Lv, Yujie Gong, Qi Sha, Xinyan Zhao, Wen Zhou, Lingtao Meng, Zegang Han, Lingxiao Zhang, Lingxiao Zhang, Yongwang Sun, Yongwang Sun

“…These results provide comprehensive information on the MsADF gene family in alfalfa and lay a solid foundation for elucidating their biological function.…”
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The Ripple Effect: How Hallux Valgus Deformity Influences Ankle and Knee Joint Kinematics During Gait by Longzhou Hua, Chenglin Wu, Ye Luo, Longxiang Li, Mingwei Liu, Aoqing Huang, Fangfang Li, Zhongmin Shi, Shaobai Wang

“…The 6-DOF kinematics data of ankles and knees were collected using a joint motion function analysis system while level walking at adaptive speed. …”
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