Bone Substitute in Diabetic Foot Osteomyelitis Treatment by Roberto Da Ros, Roberta Assaloni, Andrea Michelli, Barbara Brunato, Enrica Barro, Cesare Miranda

“…Individuals afflicted with DM exhibit an elevated risk for DFO development, attributable to a confluence of factors, including peripheral neuropathy, compromised circulation, and impaired immune function. Timely diagnosis and appropriate therapeutic intervention are paramount. …”
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Cell cycle-independent phospho-regulation of Fkh2 during hyphal growth regulates Candida albicans pathogenesis. by Jamie A Greig, Ian M Sudbery, Jonathan P Richardson, Julian R Naglik, Yue Wang, Peter E Sudbery

“…Here we have identified the Fkh2 transcription factor as a regulatory target of both Cdc28 and the cell wall biosynthesis kinase Cbk1, in a role distinct from its conserved function in cell cycle progression. In stationary phase yeast cells 2D gel electrophoresis shows that there is a diverse pool of Fkh2 phospho-isoforms. …”
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A stepped approach for the management of symptomatic internal derangement of the temporomandibular joint by Candan Efeoglu, Aylin Sipahi Calis, Huseyin Koca, Esra Yuksel

“…Parameters recorded were pain-free inter-incisal opening, spontaneous pain, pain on function, difficulty on chewing, and perceived disability on jaw movements. …”
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From the Uncharacterized Protein Family 0016 to the GDT1 family: Molecular insights into a newly-characterized family of cation secondary transporters by Louise Thines, Jiri Stribny, Pierre Morsomme

“…These proteins have all been identified as transporters of cations, more precisely of Mn2+, with an extra reported function in Ca2+ and/or H+ transport for some of them. …”
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Virus versus host plant microRNAs: who determines the outcome of the interaction? by Fatemeh Maghuly, Rose C Ramkat, Margit Laimer

“…These findings will improve the understanding of host- pathogen interaction pathways and the function of viral miRNAs in Euphorbiaceous crop plants.…”
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Elevating CLIC4 in Multiple Cell Types Reveals a TGF- Dependent Induction of a Dominant Negative Smad7 Splice Variant. by Anjali Shukla, Yihan Yang, Sara Madanikia, Yan Ho, Mangmang Li, Vanesa Sanchez, Christophe Cataisson, Jing Huang, Stuart H Yuspa

“…We now report that elevated CLIC4 alters Smad7 function, a feedback inhibitor of the TGF-β pathway. …”
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A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani. by Bhavna Chawla, Ravi Ranjan Kumar, Nidhi Tyagi, Gowri Subramanian, N Srinivasan, Myung Hee Park, Rentala Madhubala

“…We present here the molecular and structural basis of the function of DOHH from the protozoan parasite, Leishmania donovani, which causes visceral leishmaniasis. …”
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Identification and characterization of CONSTANS-like (COL) gene family in upland cotton (Gossypium hirsutum L.). by Darun Cai, Hui Liu, Na Sang, Xianzhong Huang

“…Tissue-specific expression showed that 42 GhCOL genes may function as tissue-specific regulators in different cells or organs. …”
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Noncanonical role for the host Vps4 AAA+ ATPase ESCRT protein in the formation of Tomato bushy stunt virus replicase. by Daniel Barajas, Isabel Fernández de Castro Martín, Judit Pogany, Cristina Risco, Peter D Nagy

“…In this paper, we show an unexpected key role for the conserved Vps4p AAA+ ATPase, whose canonical function is to disassemble the ESCRT complexes and recycle them from the membranes back to the cytosol. …”
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O POCZĄTKACH KLASYFIKACJI ZABYTKÓW.O WADACH I ZALETACH POLSKICH SYSTEMÓW WARTOŚCIOWANIA ZABYTKÓW by Jakub Lewicki

“…The lists must be verified by academic authorities from various communities (art and architecture historians, conservators, etc.) and all works must be carried out in compliance with currently binding regulations. …”
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Inwardly rectifying potassium channels: Critical insights for insect species and Apis mellifera by Fabien Sourisseau, Craig A. Doupnik, Pierre Charnet, Mohamed Chahine

“…Electrophysiological studies have confirmed that Drosophila Kir channels function in a way analogous to their mammalian counterparts, indicating that their roles in cellular and developmental signaling have been evolutionarily conserved. …”
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Application of a new dual localization-affinity purification tag reveals novel aspects of protein kinase biology in Aspergillus nidulans. by Colin P De Souza, Shahr B Hashmi, Aysha H Osmani, Stephen A Osmani

“…We demonstrate that the single TOR kinase of A. nidulans locates to vacuoles and vesicles, suggesting that the function of endomembranes as major TOR cellular hubs is conserved in filamentous fungi. …”
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Augmentation cystoplasty in children with stages III and IV chronic kidney disease secondary to neurogenic bladder by Sanjay Sinha, Mehul Shah

“…This improved further 1 year following AC (61 mL/min/1.73 m2, p=0.036) with stable function at 7 years. There was improvement in somatic growth, hydronephrosis, and fUTI despite no ureteric re-implantation. …”
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Metaphors of Political Identity: Disraeli and the Visual Rhetoric of Punch by Robert O’Kell

“…Such representations raise questions about the rhetorical function of humour so directed and about the relationship between Punch and its readers.…”
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Sensing of immature particles produced by dengue virus infected cells induces an antiviral response by plasmacytoid dendritic cells. by Elodie Décembre, Sonia Assil, Marine L B Hillaire, Wanwisa Dejnirattisai, Juthathip Mongkolsapaya, Gavin R Screaton, Andrew D Davidson, Marlène Dreux

“…Due to an evolutionarily conserved suboptimal cleavage of the precursor membrane protein (prM), DENV infected cells release uncleaved prM containing-immature particles, which are deficient for membrane fusion function. …”
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A Lightweight Citrus Object Detection Method in Complex Environments by Qiurong Lv, Fuchun Sun, Yuechao Bian, Haorong Wu, Xiaoxiao Li, Xin Li, Jie Zhou

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A new role for Holliday junction resolvase Yen1 in processing DNA replication intermediates exposes Dna2 as an accessory replicative helicase by Benoît Falquet, Ulrich Rass

“…A study by Ölmezer et al. (2016) has recently identified a role for the structure-specific nuclease Yen1 (GEN1 in human) in the resolution of dead-end DNA replication intermediates after RF arrest. This new function of Yen1 is distinct from its previously known role as a Holliday junction resolvase, mediating the removal of branched HR intermediates, and it becomes essential for viable chromosome segregation in cells with a defective Dna2 helicase. …”
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Regulation of the plastochron by three many-noded dwarf genes in barley. by Ken-Ichiro Hibara, Masayuki Miya, Sean Akira Benvenuto, Naoko Hibara-Matsuo, Manaki Mimura, Takanori Yoshikawa, Masaharu Suzuki, Makoto Kusaba, Shin Taketa, Jun-Ichi Itoh

“…We propose that MND genes function in the regulation of the plastochron and leaf growth and revealed conserved and diverse aspects of plastochron regulation via comparative analysis of barley and rice.…”
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RidA proteins contribute to fitness of S. enterica and E.coli by reducing 2AA stress and moderating flux to isoleucine biosynthesis by Ronnie L. Fulton, Bryce R. Sawyer, Diana M Downs

“…Because the phenotypes caused by a lack of RidA are dependent on the unique structure of each metabolic network, the link between RidA function and 2AA stress is difficult to demonstrate in some organisms. …”
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Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. by Anatoly Urisman, Ross J Molinaro, Nicole Fischer, Sarah J Plummer, Graham Casey, Eric A Klein, Krishnamurthy Malathi, Cristina Magi-Galluzzi, Raymond R Tubbs, Don Ganem, Robert H Silverman, Joseph L DeRisi

“…Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. …”
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