Insights into the protein ubiquitinome in the host‒pathogen interplay during Mycobacterium tuberculosis infection by Qishun Feng, Qiao Lin, Guoxin Huang, Siqi Li, Yating Xu, Taosheng Ye, Guoliang Zhang

“…Furthermore, the ubiquitination levels of numerous proteins involved in conserved physiological processes, such as ribosome biogenesis, spliceosome function, nucleocytoplasmic transport, and mRNA surveillance, were also altered, suggesting that these pathways may be regulated by ubiquitination during Mtb infection. …”
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Rbm3 deficiency leads to transcriptome-wide splicing alterations by Steffen Erkelenz, Marta Grzonka, Antonios Papadakis, Heiner Schaal, Jan H. J. Hoeijmakers, Ákos Gyenis

“…On the basis of these findings, we propose a novel, undescribed function of Rbm3 in RNA splicing that contributes to the preservation of transcriptome integrity.…”
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Internal Optimization Stochastic Model of Virtual Power Plant Participating in Gas and Electricity Market by Yuanyuan PENG, Renjun ZHOU, Ziqi ZENG, Jian FENG, Yuanlin CHENG, Shaofeng FANG

“…In order to fully exploit the economic benefits of VPPs, a stochastic optimization scheduling model is proposed for electric-thermal-gas VPPs with consideration of the uncertainty of electricity price and wind-photovoltaic under gas and electricity market. The objective function of the model is the total benefit of VPPs, which is the difference between the sales of electricity, heat and gas and the cost for electricity to gas conversion, carbon capture, carbon emission and fuel. …”
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Dental approach in unilateral osteoarthritis of temporomandibular joint: case report by Carlos Wallace Cunha, Carolina Rodrigues, Lais Valencise Magri, Bruno Henrique Figueiredo Matos, Cesar Bataglion, Marcelo Oliveira Mazzetto

“…The patient underwent treatment by oclusal splint (night use), overlay removable partial dentures (daytime use), application of lower level laser therapy and transcutaneous electrical nervous stimulation (TENS). Masticatory function, mouth opening, and aesthetics improved. Conclusion: Conservative therapies may be a good option for the re-establishment of the quality of life in subjects with TMJ osteoarthritis, inasmuch as it can postpone or delete the indication of more invasive techniques (e.g. surgery).   …”
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Stem Cells and Gene Therapy for Cartilage Repair by Umile Giuseppe Longo, Stefano Petrillo, Edoardo Franceschetti, Alessandra Berton, Nicola Maffulli, Vincenzo Denaro

“…Predisposing factors include traumas, inflammatory conditions, and biomechanics alterations. Conservative management of cartilage defects often fails, and patients with this lesions may need surgical intervention. …”
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A Rare Encounter: Gastric Ulcer Penetration into the Splenic Hilum Presenting with Upper Gastrointestinal Bleeding and a Massive Splenic Haematoma—Case Report and Literature Review... by Ioana-Irina Rezuș, Vasile-Claudiu Mihai, Diana Elena Floria, Andrei Olteanu, Vlad Ionut Vlasceanu, Radu Petru Soroceanu, Alin Constantin Pinzariu, Brigitta Teutsch, Sergiu Tudose-Timofeiov

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Soil-Gradient-Derived Bacterial Synthetic Communities Enhance Drought Tolerance in <i>Quercus pubescens</i> and <i>Sorbus domestica</i> Seedlings by Ivan Aleksieienko, Mariana Fernandes Hertel, Jérôme Reilhan, Marie de Castro, Bertrand Légeret, Halley Caixeta Oliveira, Ilja M. Reiter, Catherine Santaella

“…SynComs were assembled based on functional complementarity and ecological origin. Biofilm assays showed that even weak individual producers could enhance community-level performance. …”
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Total tocopherol levels in maize grain depend on chlorophyll biosynthesis within the embryo by Sam Herr, Xiaowei Li, Di Wu, Charles T. Hunter, Maria Magallanes-Lundback, Joshua C. Wood, Nicholas Kaczmar, C. Robin Buell, Dean DellaPenna, Michael A. Gore

“…Abstract Background Tocopherols are a class of lipid-soluble compounds that have multiple functional roles in plants and exhibit vitamin E activity, an essential nutrient for human and animal health. …”
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Identification and expression profiling of the CoDof genes involved in fatty acid/lipid biosynthesis of tetraploid Camellia oleifera by Guang Zhao, Guang Zhao, Lina Chen, Lin Zhang, Chancan Liao, Jin Wang

“…After physiological data determination at various levels, differential expression analysis and correlation analysis of fatty acid/lipid synthesis genes revealed that CoDof30.1 is a typical candidate nuclear-localized transcription factor which significantly highly expressed in the middle period of seed development.DiscussionOur findings not only comprehensively characterize the genomic organization of CoDof family but also propose a functional candidate for lipid biosynthesis regulation, thereby advancing molecular breeding strategies and elite cultivar selection in COL-tetra.…”
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The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer by Li Qiu, Shourong Wu, Lei Zhang, Wenfang Li, Debing Xiang, Vivi Kasim

“…This review summarizes the current knowledge on the functional roles and underlying molecular mechanisms of IGF2BP1 in regulating cancer hallmarks. …”
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Characterization of Trileucine Motif in the C-Terminus of the Equine Lutropin/Choriogonadotropin Receptor by Sang-Gwon Kim, Munkhzaya Byambaragchaa, Sei Hyen Park, Ha-Rin Jeong, Jae-Hyek Park, Myung-Hum Park, Myung-Hwa Kang, Kwan-Sik Min

“…This study aimed to investigate the functional significance of the equine LH/CGR (eLH/CGR) trileucine motif in signal transduction. …”
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Genome-wide identification and expression analysis of sucrose phosphate synthase and sucrose-6-phosphate phosphatase family genes in Camellia sinensis by Shicai Liang, Huan Wang, Hiroto Yamashita, Shuning Zhang, Xuxu Lang, Jiaxuan Yue, Shan He, Yu Wang, Kai Fan, Zhaotang Ding, Takashi Ikka, Wenjun Qian

“…In conclusion, this study will provide a theoretical basis for further functional research of SPS and SPP in plants.…”
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Computational analysis of zoanthamine alkaloids from Zoanthus sp. as potential DKK1 and GSK-3β inhibitors for osteoporosis therapy via Wnt signaling by Ngoc-Thac Pham, Huong-Giang Le, Bo-Rong Peng, Lo-Yun Chen, Mohamed El-Shazly, Jui-Hsin Su, Mei-Hsien Lee, Kuei-Hung Lai

“…This study employed an integrated computational approach—combining molecular docking, extensive molecular dynamics (MD) simulations, and density functional theory (DFT) calculations—to assess the inhibitory potential of 69 zoanthamine-type alkaloids against DKK1 and GSK-3β. …”
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Genome-wide identification of GATA family genes in sweet potato (Ipomoea batatas L.) and their expression patterns under abiotic stress by Chong Wang, Mengjiao Lan, Manqiu Xiao, Ying Peng, Ying Peng, Hao Pan, Jiaqi Deng, Wensheng Wu

“…Overall, this experiment conducted a systematic exploration of GATA genes by investigating their evolutionary relationships, structural characteristics, functional properties, and expression patterns, thereby establishing a theoretical foundation for further in-depth research on the features of the GATA gene family.…”
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Genomic Organization and Expression Profiling of GOLDEN2-like Transcription Factor Genes in Eggplant and Their Role in Heat Stresses by Chuying Yu, Rui Xiang, Yaqin Jiang, Weiliu Li, Qihong Yang, Guiyun Gan, Liangyu Cai, Peng Wang, Wenjia Li, Yikui Wang

“…This study provides valuable candidate gene resources for further functional research and will benefit eggplant molecular breeding.…”
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Genome-wide identification and stress-responsive expression profiling of the TCP gene family in Cenchrus fungigraminus under drought and cold stress by Shijie Ke, Xin He, Mengmeng Zhang, Lin Luo, Yuxin Chen, Yixue Cui, Yelin Huang

“…Conclusions In total, 40 CfuTCP genes were identified in C. fungigraminus. Functional predictions suggested the roles of CfuTCPs in modulating multiple C. fungigraminus physiological processes and metabolic pathways. …”
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Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis by Cai-Ling Ke, Shi Qian Lew, Yi Hsieh, Szu-Cheng Chang, Ching-Hsuan Lin

“…Although the function of AMPK has been well studied in Saccharomyces cerevisiae and Candida albicans, the role of AMPK in Candida tropicalis has never been investigated. …”
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Changes in insulin, adiponectin and lipid concentrations with age are associated with frailty and reduced quality of life in dogs by Brennen McKenzie, Matthew Peloquin, Jessica L. Graves, Frances Chen, Ashley Tovar, Tennery A. Carttar, Katya Tucker, Kenny Vo, Michelle Nelson, Kaitlyn M. Super, Jessica Austriaco, Sunny Y. Weber, Alexander Naka, Erin E. McCandless, Karen Greenwood, Dina Juarez-Salinas, Celine-Lea Halioua-Haubold, Ellen R. Ratcliff

“…Abstract Declining metabolic function with aging is a conserved phenotype across many species. …”
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A novel neutralizing monoclonal antibody recognizes a linear antigenic epitope of the spike protein of swine acute diarrhoea syndrome coronavirus by Lin Zhang, Hui-Zhen Liu, Yuexiao Lian, Yujun Zhu, Miaoli Wu, Jianbo Liu, Feng Cong

“…Amino acid sequence alignment revealed that the epitope of the 5D6 mAb was conserved among SADS-CoV strains. This study helps elucidate the S protein function of SADS-CoV, and the 5D6 mAb may be used to develop diagnostic and treatment tools for detecting SADS-CoV infection.…”
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Mycobacterium tuberculosis Rv1048c affects the biological characteristics of recombinant Mycobacterium smegmatis by Dan-Ni Li, Xin-Yue Liu, Jin-Biao Xu, Kun Shi, Jian-Ming Li, Nai-Chao Diao, Ying Zong, Fan-Li Zeng, Rui Du

“…Rv1048c exists only in pathogenic Mycobacterium tuberculosis and is highly conserved; however its function is still unclear. The recombinant Mycobacterium smegmatis strain Ms_Rv1048c, with heterologous expression of the Rv1048c gene, was constructed by using the pMV261 expression plasmid. …”
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