The recurrence of colonic volvulus due to nonrotation after intestinal resection in adulthood: a case report by Yusuke Sakimura, Hirotaka Kitamura, Noriyuki Inaki, Hiroyuki Bando

“…The involved transverse colon was resected, and the intestine was reconstructed by functional end-to-end anastomosis (FEEA). Six years after the initial surgery, the patient presented to the ER with abdominal fullness and lower abdominal pain. …”
Get full text

The yeast La related protein Slf1p is a key activator of translation during the oxidative stress response. by Christopher J Kershaw, Joseph L Costello, Lydia M Castelli, David Talavera, William Rowe, Paul F G Sims, Mark P Ashe, Simon J Hubbard, Graham D Pavitt, Chris M Grant

“…In paralell, transcriptome analysis of slf1Δ and sro9Δ mutant strains indicated altered gene expression in similar functional classes of mRNAs following loss of each factor. …”
Get full text

Protein hydrolysates are avoided by herbivores but not by omnivores in two-choice preference tests. by Kristin L Field, Alexander A Bachmanov, Julie A Mennella, Gary K Beauchamp, Bruce A Kimball

“…<h4>Background</h4>The negative sensory properties of casein hydrolysates (HC) often limit their usage in products intended for human consumption, despite HC being nutritious and having many functional benefits. Recent, but taxonomically limited, evidence suggests that other animals also avoid consuming HC when alternatives exist.…”
Get full text

Comprehensive genome-wide characterization of NAC transcription factors in Barley influence insights into stress tolerance and evolutionary dynamics by Muhammad Arif, Noman Mahmood, Ayesha Fazal Nawaz, Mohamed A. El-Sheikh, Saleh Alansi, Parvaiz Ahmad

“…The investigation of microRNA (miRNA) interactions identified miRNA164 and Hvu-miR156 as key regulators of HvNAC expression under drought stress, underscoring the functional importance of these genes in stress adaptation. …”
Get full text

Intracerebral Hemorrhage: A Fatal Complication of Severe Preeclampsia&amp;mdash;A Rare Case Report in a Resource-Limited Setting by Mohamed IA, Omar AA, Hassan MM, Hassan MA, Adan ZM, Mohamed ZA

“…Follow-up after four weeks demonstrated complete functional recovery, with resolution confirmed by repeat CT.Conclusion: This case uniquely underscores the critical importance of timely multidisciplinary care and robust antenatal monitoring in mitigating severe complications such as ICH associated with preeclampsia. …”
Get full text

Effectiveness of Lateral Column lengthening in Symptomatic Flexible Flatfoot of the Pediatric and Adolescent Population: An updated Systematic Review by Karthick Rangasamy, Akash K Ghosh, Vivek P Ksheerasagar, Jai P Khatri, Nirmal R Gopinathan

“…Background: Pes planovalgus is one of the most common pediatric foot deformities; one can manage it most conservatively. Surgery is only indicated for symptomatic flexible flatfoot with failed conservative treatment. …”
Get full text

Identification of key genes and immune infiltration mechanisms in limb ischemia-reperfusion injury: a bioinformatics and experimental study by Qiyun Shi, Taotao Tian, Yanfeng Li

“…Pharmacological inhibition confirmed their functional roles: Box5 and U-73122 treatment reduced expression of WNT5A and PLC versus IRI controls (P&lt;0.05), showing IRI-induced muscle fiber disruption, edema, and inflammation. …”
Get full text

The Requirement of Turkey Herpesvirus (HVT) Glycoprotein C During Natural Infection in Chickens and Turkeys by Huai Xu, Widaliz Vega-Rodriguez, Kathrine Van Etten, Keith Jarosinski

“…These data confirm the host-specific transmission of HVT in turkeys and suggest that the essential function of alphaherpesvirus gC proteins is conserved. …”
Get full text

Chest Wall Perforator Flaps in Partial Breast Reconstruction: A Systematic Review and Meta-analysis by Caterina M. Nava, MS, Gauthier Zinner, MS, Jérôme Martineau, MD, Carlo M. Oranges, MD, PhD

“…In such cases, muscle-sparing chest wall perforator flaps (CWPFs) offer a reliable, function-preserving reconstruction option with low donor-site morbidity, making them particularly useful for volume replacement. …”
Get full text

Minimization of the Bacillus subtilis divisome suggests FtsZ and SepF can form an active Z-ring, and reveals the amino acid transporter BraB as a new cell division influencing fact... by Ilkay Celik Gulsoy, Terrens N V Saaki, Michaela Wenzel, Simon Syvertsson, Taku Morimoto, Tjalling K Siersma, Leendert W Hamoen

“…After extensive phenotypic testing of these mutations, we found an unexpected cell division regulation function for the branched chain amino acid transporter BraB, which may be related to a change in fatty acid composition. …”
Get full text

Alpha-Synuclein Dysregulation in Systemic Pathophysiology of Synucleinopathies by Hallie H. Dolin, Bowen Zhou, Robert W. Maitta

“…This protein has been recognized as an essential factor in normal hematopoietic and immune systems function, and its deficiency leads to an abnormal phenotype, in hematopoietic and immune cell lineages. …”
Get full text

Regulatory role of MicroRNA164 in heat and salinity stress responses via candidate target genes during seed germination in petunia by Tao Jiang, Keila Rodriguez, Sameena Ejaz Tanwir, Fangchen Liu, Fida Hussain, Jaideep Chandranshu Cherukula, Heqiang Huo

“…Phylogenetic analysis revealed nine distinct clades, indicating both conserved and divergent functions of NAC proteins. …”
Get full text

A missense mutation in the Sin3 subunit of Rpd3 histone deacetylase complex bypasses the requirement for FNG1 in wheat scab fungus by Huaijian Xu, Ruoxuan Jiang, Xianhui Fu, Qinhu Wang, Yutong Shi, Xiaofei Zhao, Cong Jiang, Hang Jiang

“…Sin3, the largest subunit of Rpd3 complex, is conserved in a broad range of eukaryotes. Despite being a molecular scaffold for complex assembly, the functional sites and mechanism of action of Sin3 remain unexplored. …”
Get full text

Fragment Reattachment after Atypical Crown Fracture in Maxillary Central Incisor by Vanessa Torraca Peraro Vaz, Cristina Dupim Presoto, Keren Cristina Fagundes Jordão, André Gustavo Paleari, Andrea Abi-Rached Dantas, José Claudio Martins Segalla, Osmir Batista de Oliveira Junior

“…This technique restores the aesthetics and function of the dental element with minimal discomfort to the patient.…”
Get full text

FtsZ as a novel target for antibiotics development: Promises and challenges by Ming-Wei Wang, Kaini Hang, Wei Han, Xin Li, Qingtong Zhou, Dehua Yang

“…Filamenting temperature-sensitive mutant Z (FtsZ), a protein essential for bacterial cell division, is highly conserved across bacterial species but absent in humans, positioning it as a strategic target for the development of antibiotics. …”
Get full text

Cloning and expression analysis of maize fucosyltransferase gene SPINDLY by LI Bowen, WANG Zhiqin, ZHU Xiaona, ZHU Zhenyu, GAO Xiaoxiao*

“…In order to explore the function of maize fucosyltransferase gene(ZmSPY), this study first analyzed the conserved domain, amino acid sequence and physicochemical properties of ZmSPY protein by bioinformatics means, and cloned the gene from maize root tissue to construct the GFP fusion protein expression vector. …”
Get full text

The dual role of cyclin C connects stress regulated gene expression to mitochondrial dynamics by Randy Strich, Katrina F. Cooper

“…In addition, we will detail this new function mediating mitochondrial fission and PCD. Although both these roles of cyclin C are conserved, this review will concentrate on cyclin C's dual role in the budding yeast Saccharomyces cerevisiae.…”
Get full text

The Rvv two-component regulatory system regulates biofilm formation and colonization in Vibrio cholerae. by Giordan Kitts, Andrew Rogers, Jennifer K Teschler, Jin Hwan Park, Michael A Trebino, Issac Chaudry, Ivan Erill, Fitnat H Yildiz

“…The rvv operon encodes RvvA, the HK; RvvB, the cognate RR; and RvvC, a protein of unknown function. Deletion of rvvA increased transcription of biofilm genes and altered biofilm formation, while deletion of rvvB or rvvC lead to no changes in biofilm gene transcription. …”
Get full text

Altered Immune Profiles of Natural Killer Cells in Chronic Hepatitis B Patients: A Systematic Review and Meta-Analysis. by Qiong-Fang Zhang, Jian-Ying Shao, Wen-Wei Yin, Yang Xia, Ling Chen, Xing Wang, Huai-Dong Hu, Peng Hu, Hong Ren, Da-Zhi Zhang

“…Thus, we performed a meta-analysis to characterize reliably the immune profiles of NK cells after CHB infection, specifically frequency, phenotype, and function.<h4>Methods</h4>A literature search of the computer databases MEDLINE, PUBMED, EMBASE, and Cochrane Center Register of Controlled Trails was performed and 19 studies were selected. …”
Get full text

Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core. by Dagmara I Kisiela, Pearl Magala, Gianluca Interlandi, Laura A Carlucci, Angelo Ramos, Veronika Tchesnokova, Benjamin Basanta, Vladimir Yarov-Yarovoy, Hovhannes Avagyan, Anahit Hovhannisyan, Wendy E Thomas, Ronald E Stenkamp, Rachel E Klevit, Evgeni V Sokurenko

“…Our study shows that allosteric transitions in bacterial adhesins depend on toggle switch residues and that an antibody that blocks the switch effectively disables adhesive protein function.…”
Get full text